title: Neuropeptide Y receptor Y1
text: # Neuropeptide Y receptor Y1
  
  Neuropeptide Y receptor type 1 is a protein that in humans is encoded by the NPY1R gene.
  
  ## Selective ligands
  
  ### Agonists
  
  * Neuropeptide Y (endogenous agonist, non subtype selective)
  * Peptide YY
  
  ### Antagonists
  
  **Peptide**
  
  * BVD-10 (selective $NPY_1$ antagonist, CAS# 262418-00-8)
  * GR-231,118 (mixed $NPY_1$ antagonist / $NPY_4$ agonist, CAS# 158859-98-4)
  
  **Non-peptide**
  
  * BIBO-3304 (CAS# 191868-14-1)
  * BIBP-3226 (CAS# 159013-54-4)
  * PD-160,170 (CAS# 181468-88-2)
  
  ## Available Structures
  
  * 5ZBH (Neuropeptide Y1 bound to antagonist BMS-193835)
  * 5ZBQ (Neuropeptide Y1 bound to antagonist UR-MK299)
  