title: VCHSR
text: # VCHSR
  
  VCHSR is a drug used in scientific research which acts as a selective antagonist of the cannabinoid receptor $CB_1.$ It is derived from the widely used $CB_1$ antagonist rimonabant, and has similar potency and selectivity for the $CB_1$ receptor, but has been modified to remove the hydrogen bonding capability in the C-3 substituent region, which removes the inverse agonist effect that rimonabant produces at high doses, so that VCHSR instead acts as a neutral antagonist, blocking the receptor but producing no physiological effect of its own.
  
  