title: Cefazaflur
text: # Cefazaflur
  
  Cefazaflur (INN) is a first-generation cephalosporin antibiotic.
  
  ## Synthesis
  
  Cefazaflur stands out among this group of analogues because it lacks an arylamide C-7 side chain (see cephacetrile for another example).
  
  Cefazaflur is synthesized by reaction of 3-(1-methyl-1H-tetrazol-5-ylthiomethylene)-7-amino-cephem-4-carboxylic acid (1) with trifluoromethylthioacetyl chloride (2).
  
  