title: SASS6
text: # SASS6
  
  Spindle assembly abnormal protein 6 homolog (SAS-6) is a protein that in humans is encoded by the SASS6 gene.
  
  ## Function
  
  SAS-6 is necessary for centrosome duplication and functions during procentriole formation; SAS-6 functions to ensure that each centriole seeds the formation of a single procentriole per cell cycle.
  
  ## Clinical significance
  
  Mutations in SASS6 are associated to MCPH.
  
  