title: Naloxol
text: # Naloxol
  
  Naloxol is an opioid antagonist closely related to naloxone. It exists in two isomeric forms, α-naloxol and β-naloxol.
  
  α-naloxol is a human metabolite of naloxone. Synthetically, α-naloxol can be prepared from naloxone by reduction of the ketone group, and β-naloxol can be prepared from α-naloxol by a Mitsunobu reaction.
  
  Naloxol can be said to be the oxymorphol analogue of naloxone.
  
  