title: Dynein axonemal light chain 1
text: # Dynein axonemal light chain 1
  
  Dynein axonemal light chain 1, (LC1) is a protein that in humans is encoded by the DNAL1 gene.
  
  ## Function
  
  LC1 is a component of outer dynein arms, which contain the molecular motors for ATP-dependent cilia movement.
  
  ## Clinical significance
  
  Mutations in the DNAL1 gene are associated with primary ciliary dyskinesia.
  
  