title: PEX16
text: # PEX16
  
  Peroxisomal membrane protein PEX16 is a protein that in humans is encoded by the PEX16 gene.
  
  ## Function
  
  The protein encoded by this gene is an integral peroxisomal membrane protein. An inactivating nonsense mutation localized to this gene was observed in a patient with Zellweger syndrome of the complementation group CGD/CG9. Expression of this gene product morphologically and biochemically restores the formation of new peroxisomes, suggesting a role in peroxisome organization and biogenesis. Alternative splicing has been observed for this gene and two variants have been described.
  
  ## Interactions
  
  PEX16 has been shown to interact with PEX19.
  
  