title: YM-348
text: # YM-348
  
  YM-348 is an indazole derivative drug which acts as a potent and selective $5-HT_{2C}$ receptor agonist, with an $EC_{50}$ of 1nM and 15x selectivity over $5-HT_{2A},$ although it only has moderate selectivity of 3x over the closely related $5-HT_{2B}$ receptor. It has thermogenic and anorectic effects in animal studies, making it potentially useful for the treatment of obesity.
  
  