title: Comparison of force-field implementations
text: # Comparison of force-field implementations
  
  This is a table of notable computer programs implementing molecular mechanics force fields.
  
  | Program | OPLS | AMBER | CHARMM | GAFF | MMFF | QVBMM | UFF | Comments |
  | - | - | - | - | - | - | - | - | - |
  | Abalone | UA | 94, 96, 99SB, 03, GS, ii, Automatic FF generator | No | No | No | No | UFF-Dreiding-like field | For proteins, DNA, ligands |
  | AMBER | Yes | Yes | Via chamber tool since v11 | Yes | No | No | No | |
  | Ascalaph Designer | UA | 94, 99SB, 03 | No | No | No | No | No | |
  | Avogadro | No | No | No | Yes | 94, 94s | No | Yes | |
  | Balloon | No | No | No | No | 94 | No | No | MMFF94-like |
  | BOSS | Yes | No | No | No | No | No | No | |
  | CHARMM | Yes* | Yes* | Yes* | Via CHARMM-GUI | Full MMFF94, but code rumored unmaintained | No | No | * in standard distribution |
  | Gabedit | No | Yes | No | Yes | Yes | No | No | |
  | Gaussian mm utility | No | Yes | No | No | No | No | Yes | Dreiding field available |
  | GROMACS | Yes | Yes* | Yes* | Yes | No | No | No | * in standard distribution since v4.5.0 |
  | MOE | AA | 89, 94, 99, also with Extended Hückel Theory | 22, 27 | No | 94(s) | No | No | |
  | NAMD | Yes | Yes | Yes | Yes | No | No | No | |
  | Q | Yes | Yes | Yes | No | No | No | No | For biopolymers |
  | Tinker | UA, AA, AA/L | 94, 96, 98, 99 | 19, 27 | No | 94 | No | No | For proteins, organic molecules |
  | Towhee | UA, AA | 86 | 19, 22, 27 | No | 94 | No | Yes | Monte Carlo |
  | Yasara | No | 94, 96, 99, 03 | No | No | No | No | No | Plus custom fields for hires refinement |
  