title: MINK1
text: # MINK1
  
  Misshapen-like kinase 1 is an enzyme that in humans is encoded by the MINK1 gene.
  
  ## Function
  
  Misshapen-like kinase 1 is a serine/threonine kinase belonging to the germinal center kinase (GCK) family. The protein is structurally similar to the kinases that are related to NIK and may belong to a distinct subfamily of NIK-related kinases within the GCK family. Studies of the mouse homolog indicate an up-regulation of expression in the course of postnatal mouse cerebral development and activation of the cJun N-terminal kinase (JNK) and the p38 pathways. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified.
  
  ## Interactions
  
  MINK1 has been shown to interact with NCK1.
  
  