title: List of Cash Box Top 100 number-one singles of 1981
text: # List of Cash Box Top 100 number-one singles of 1981
  
  These are the number-one hits on the Top 100 Singles chart in 1981 as published by Cash Box magazine.
  
  Key :
  
  | † | Indicates best-performing single of 1981 |
  | - | - |
  | Issue date | Song | Artist |
  | January 3 | "(Just Like) Starting Over" | John Lennon |
  | January 10 | "(Just Like) Starting Over" | John Lennon |
  | January 17 | "(Just Like) Starting Over" | John Lennon |
  | January 24 | "(Just Like) Starting Over" | John Lennon |
  | January 31 | "The Tide Is High" | Blondie |
  | February 7 | "The Tide Is High" | Blondie |
  | February 14 | "Celebration" | Kool & the Gang |
  | February 21 | "I Love a Rainy Night" | Eddie Rabbitt |
  | February 28 | "9 to 5" | Dolly Parton |
  | March 7 | "Keep on Loving You" | REO Speedwagon |
  | March 14 | "Woman" | John Lennon |
  | March 21 | "Woman" | John Lennon |
  | March 28 | "Rapture" | Blondie |
  | April 4 | "Rapture" | Blondie |
  | April 11 | "Kiss on My List" | Daryl Hall and John Oates |
  | April 18 | "Morning Train (Nine to Five)" | Sheena Easton |
  | April 25 | "Morning Train (Nine to Five)" | Sheena Easton |
  | May 2 | "Morning Train (Nine to Five)" | Sheena Easton |
  | May 9 | "Morning Train (Nine to Five)" | Sheena Easton |
  | May 16 | "Morning Train (Nine to Five)" | Sheena Easton |
  | May 23 | "Being With You" | Smokey Robinson |
  | May 30 | "Bette Davis Eyes" | Kim Carnes |
  | June 6 | "Bette Davis Eyes" | Kim Carnes |
  | June 13 | "Bette Davis Eyes" | Kim Carnes |
  | June 20 | "Medley: Intro Venus / Sugar Sugar / No Reply / I'll Be Back / Drive My Car / Do You Want To Know a Secret / We Can Work It Out / I Should Have Known Better / Nowhere Man / You're Going To Lose That Girl / Stars on 45" | Stars on 45 |
  | June 27 | "Medley: Intro Venus / Sugar Sugar / No Reply / I'll Be Back / Drive My Car / Do You Want To Know a Secret / We Can Work It Out / I Should Have Known Better / Nowhere Man / You're Going To Lose That Girl / Stars on 45" | Stars on 45 |
  | July 4 | "Bette Davis Eyes" | Kim Carnes |
  | July 11 | "Bette Davis Eyes" | Kim Carnes |
  | July 18 | "The One That You Love" | Air Supply |
  | July 25 | "Jessie's Girl" | Rick Springfield |
  | August 1 | "Elvira" | Oak Ridge Boys |
  | August 8 | "Theme From “Greatest American Hero" | Joey Scarbury |
  | August 15 | "Endless Love" † | Diana Ross and Lionel Richie |
  | August 22 | "Endless Love" † | Diana Ross and Lionel Richie |
  | August 29 | "Endless Love" † | Diana Ross and Lionel Richie |
  | September 5 | "Endless Love" † | Diana Ross and Lionel Richie |
  | September 12 | "Endless Love" † | Diana Ross and Lionel Richie |
  | September 19 | "Endless Love" † | Diana Ross and Lionel Richie |
  | September 26 | "Endless Love" † | Diana Ross and Lionel Richie |
  | October 3 | "Endless Love" † | Diana Ross and Lionel Richie |
  | October 10 | "Endless Love" † | Diana Ross and Lionel Richie |
  | October 17 | "Arthur's Theme (Best That You Can Do)" | Christopher Cross |
  | October 24 | "Arthur's Theme (Best That You Can Do)" | Christopher Cross |
  | October 31 | "Arthur's Theme (Best That You Can Do)" | Christopher Cross |
  | November 7 | "Arthur's Theme (Best That You Can Do)" | Christopher Cross |
  | November 14 | "Private Eyes" | Daryl Hall and John Oates |
  | November 21 | "Physical" | Olivia Newton-John |
  | November 28 | "Physical" | Olivia Newton-John |
  | December 5 | "Physical" | Olivia Newton-John |
  | December 12 | "Physical" | Olivia Newton-John |
  | December 19 | "Physical" | Olivia Newton-John |
  | December 26 | "Physical" | Olivia Newton-John |
  