title: Cardoreovirus
text: # Cardoreovirus
  
  Cardoreovirus is a genus of double-stranded RNA viruses in the family Reoviridae and subfamily Sedoreovirinae. Crabs serve as natural hosts. There is only one species in this genus: Eriocheir sinensis reovirus. Diseases associated with this genus include: trembling disease. The name derives from Latin words "carcinus" which means crab and "doeca" which means twelve in reference to the number genome segments.
  
  ## Structure
  
  Viruses in the genus Cardoreovirus are non-enveloped. They have an icosahedral capsid that is three-layered. The inner shell has T=2 symmetry and the middle shell has T=13 symmetry. The diameter is around 55 nm.
  
  ## Genome
  
  The genome is made of double-stranded RNA. It is linear and has twelve segments.
  
  ## Life cycle
  
  Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment to host receptors, which mediates endocytosis. Replication follows the double-stranded RNA virus replication model. Double-stranded RNA virus transcription is the method of transcription. The virus exits the host cell by monopartite non-tubule guided viral movement. Crabs serve as the natural host. Transmission routes are passive diffusion.
  
  ## Taxonomy
  
  The genus contains one species:
  
  * Eriocheir sinensis reovirus
  