title: Mischivirus
text: # Mischivirus
  
  Mischivirus is a genus of viruses in the order Picornavirales, in the family Picornaviridae. Bats serve as natural hosts. There are five species in this genus.
  
  ## Taxonomy
  
  The genus contains the following five species:
  
  * Mischivirus A
  * Mischivirus B
  * Mischivirus C
  * Mischivirus D
  * Mischivirus E
  
  ## Structure
  
  Viruses in Mischivirus are non-enveloped, with icosahedral, spherical, and round geometries, and T=pseudo3 symmetry. The diameter is around 30 nm. Genomes are linear and non-segmented, around 8.5kb in length.
  
  | Genus | Structure | Symmetry | Capsid | Genomic arrangement | Genomic segmentation |
  | - | - | - | - | - | - |
  | Mischivirus | Icosahedral | Pseudo T=3 | Non-enveloped | Linear | Monopartite |
  
  ## Life cycle
  
  Viral replication is cytoplasmic. Entry into the host cell is achieved by attachment of the virus to host receptors, which mediates endocytosis. Replication follows the positive stranded RNA virus replication model. Positive stranded RNA virus transcription is the method of transcription. Translation takes place by ribosomal skipping. The virus exits the host cell by lysis, and viroporins. Bats serve as the natural host.
  
  | Genus | Host details | Tissue tropism | Entry details | Release details | Replication site | Assembly site | Transmission |
  | - | - | - | - | - | - | - | - |
  | Mischivirus | Bats | None | Cell receptor endocytosis | Lysis | Cytoplasm | Cytoplasm | Unknown |
  