title: TTI2
text: # TTI2
  
  TELO2 interacting protein 2 is a protein that in humans is encoded by the TTI2 gene.
  
  ## Function
  
  This gene encodes a regulator of the DNA damage response. The protein is a component of the Triple T complex (TTT) which also includes telomere length regulation protein and TELO2 interacting protein 1.
  
  The TTT complex is involved in cellular resistance to DNA damage stresses and may act as a regulator of phosphoinositide-3-kinase-related protein kinase (PIKK) abundance.
  
  