title: 2,4,5-Trimethoxyphenethylamine
text: # 2,4,5-Trimethoxyphenethylamine
  
  2,4,5-Trimethoxyphenethylamine (2C-O or 2C-OMe) or is a phenethylamine of the 2C family and was first synthesized by Jansen in 1931. It is a positional isomer of the drug mescaline (3,4,5-trimethoxy).
  
  ## Chemistry
  
  2C-O is a member of a class of chemical compounds commonly known as phenethylamines. Its full chemical name is 2-(2,4,5-trimethoxyphenyl)ethanamine; it is also known as 2,4,5-trimethoxyphenethylamine and 2,4,5-TMPEA.
  
  ## Effects
  
  Although not centrally active itself, 2C-O appeared to potentiate the action of mescaline when employed as pretreatment 45 minutes prior to the administration of mescaline.
  
  ## Dangers
  
  The toxicity of 2C-O is not known.
  
  ## Law
  
  ### Canada
  
  As of October 31, 2016, 2C-O is a controlled substance (Schedule III) in Canada.
  
  ### United States
  
  2C-O is a Schedule I substance, as a positional isomer of mescaline.
  
  ### United Kingdom
  
  2C-O and all other compounds featured in PiHKAL are Class A drugs in the United Kingdom.
  
  