title: List of antiretroviral fixed-dose combinations
text: # List of antiretroviral fixed-dose combinations
  
  Antiretroviral drugs are used to manage HIV/AIDS. Multiple antiretroviral drugs are often combined into a single pill in order to reduce pill burden.
  
  Some of these combinations are complete single-tablet regimens; the others must be combined with additional pills to make a treatment regimen.
  
  | Brand name(s) | Ingredients (INN) | Ingredients (INN) | Ingredients (INN) | Ingredients (INN) | Ingredients (INN) | Food and Drug Administration (FDA) approval date | European Medicines Agency (EMA) approval date | Health Canada approval date | Company | Single-tablet regimen? |
  | - | - | - | - | - | - | - | - | - | - | - |
  | Brand name(s) | NRTIs / NtRTIs | NNRTI | INSTI | PI | PK enhancer | Food and Drug Administration (FDA) approval date | European Medicines Agency (EMA) approval date | Health Canada approval date | Company | Single-tablet regimen? |
  | Combivir | lamivudine zidovudine | | | | | September 26, 1997 | | | ViiV Healthcare | No |
  | Kaletra (developed countries) Aluvia (developing countries) | | | | lopinavir | ritonavir | September 15, 2000 | | | Abbott Laboratories | No |
  | Trizivir | abacavir lamivudine zidovudine | | | | | November 15, 2000 | | | ViiV Healthcare | Yes |
  | Epzicom (US) Kivexa (EU, RU) | abacavir lamivudine | | | | | August 2, 2004 | | | ViiV Healthcare | No |
  | Generics, e.g., Triomune | lamivudine stavudine | nevirapine | | | | (not approved) | | | (many companies) | Yes |
  | Generics, e.g., Duovir-N | lamivudine zidovudine | nevirapine | | | | (not approved) | | | (many companies) | Yes |
  | Truvada | emtricitabine tenofovir disoproxil | | | | | August 2, 2004 | | | Gilead Sciences | No |
  | Atripla | emtricitabine tenofovir disoproxil | efavirenz | | | | July 12, 2006 | | | Gilead Sciences Bristol-Myers Squibb | Yes |
  | Complera (US) Eviplera (EU, RU) | emtricitabine tenofovir disoproxil | rilpivirine | | | | August 10, 2011 | | | Gilead Sciences Janssen Pharmaceutica | Yes |
  | Stribild | emtricitabine tenofovir disoproxil | | elvitegravir | | cobicistat | August 27, 2012 | | | Gilead Sciences | Yes |
  | Triumeq | abacavir lamivudine | | dolutegravir | | | August 22, 2014 | | | ViiV Healthcare | Yes |
  | Evotaz | | | | atazanavir | cobicistat | January 29, 2015 | | | Bristol-Myers Squibb | No |
  | Prezcobix (US) Rezolsta (EU) | | | | darunavir | cobicistat | January 29, 2015 | | | Janssen Pharmaceutica | No |
  | Dutrebis | lamivudine | | raltegravir | | | February 6, 2015 | | | Merck & Co. | No |
  | Genvoya | emtricitabine tenofovir alafenamide | | elvitegravir | | cobicistat | November 5, 2015 | | | Gilead Sciences | Yes |
  | Odefsey | emtricitabine tenofovir alafenamide | rilpivirine | | | | March 1, 2016 | | | Gilead Sciences | Yes |
  | Descovy | emtricitabine tenofovir alafenamide | | | | | April 4, 2016 | | | Gilead Sciences | No |
  | Juluca | | rilpivirine | dolutegravir | | | November 21, 2017 | | | ViiV Healthcare | Yes |
  | Symfi, Symfi Lo | lamivudine tenofovir disoproxil | efavirenz | | | | February 5, 2018 (Symfi Lo) March 22, 2018 (Symfi) | | | Mylan | Yes |
  | Biktarvy | emtricitabine tenofovir alafenamide | | bictegravir | | | February 7, 2018 | | | Gilead Sciences | Yes |
  | Cimduo, Temixys | lamivudine tenofovir disoproxil | | | | | February 28, 2018 | | | Mylan | No |
  | Symtuza | emtricitabine tenofovir alafenamide | | | darunavir | cobicistat | July 17, 2018 | | | Janssen Pharmaceutica | Yes |
  | Delstrigo | lamivudine tenofovir disoproxil | doravirine | | | | August 30, 2018 | | | Merck & Co. | Yes |
  | Dovato | lamivudine | | dolutegravir | | | April 8, 2019 | | | ViiV Healthcare | Yes |
  | Cabenuva | | rilpivirine | cabotegravir | | | January 21, 2021 | | March 18, 2020 | ViiV Healthcare | No |
  