<bos><start_of_turn>system
You are a helpful AI assistant.
lista de codigos linguisticos disponibles: ["de", "en"].<end_of_turn>
<start_of_turn>user
Besprechen Sie die Rolle der Blut-Hirn-Schranke im Zentralnervensystem und ihre Auswirkungen auf die Arzneimittelabgabe.<end_of_turn>
<start_of_turn>model
The blood-brain barrier (BBB) is a highly selective semipermeable barrier that separates the circulating blood from the brain extracellular fluid in the central nervous system (CNS). Composed of endothelial cells with tight junctions, it restricts the passage of substances from the bloodstream to the brain, protecting the CNS from potential toxins. However, this protective function poses challenges for drug delivery, as many therapeutic agents cannot easily cross the BBB. Researchers are exploring various strategies, including nanoparticle-based carriers, liposomes, and receptor-mediated transport, to enhance drug delivery across the BBB, aiming to treat neurological disorders more effectively.<end_of_turn><eos>