Given the patient's current medication regimen and clinical findings, which health risk should be prioritized for management?
Increased risk of hypoglycemia due to metformin use without insulin. Increased risk of cardiovascular events due to combined use of NSAIDs and antihypertensives. Increased risk of renal impairment due to tramadol and naproxen. Increased risk of gastrointestinal bleeding due to tramadol use.