In managing this patient's hypertension and osteoporosis, how do lisinopril and amlodipine work together to potentially benefit the patient's condition?
Lisinopril directly increases bone mineral density, while amlodipine reduces calcium excretion. Lisinopril reduces blood pressure and protects against bone loss, while amlodipine further aids in blood pressure control. Both lisinopril and amlodipine work by decreasing bone resorption, thereby treating osteoporosis. Amlodipine enhances the antihypertensive effect of lisinopril by increasing its bioavailability.