A patient with hypertension is on a regimen including lisinopril, amlodipine, and hydrochlorothiazide. Despite this, their diastolic blood pressure remains elevated at 103 mmHg. Considering the symptom progression, what is the most likely reason for the persistent hypertension in this patient?
Development of malignant hypertension requiring urgent intervention Drug interaction between amlodipine and lisinopril reducing efficacy Incorrect initial diagnosis leading to inappropriate treatment regime Suboptimal medication adherence due to limited social contact and housing issues