Pethidine is also relatively contraindicated for use when a patient is suffering from liver, or kidney disease, has a history of seizures or epilepsy, has an enlarged prostate or urinary retention problems, or suffers from hypothyroidism, asthma, or Addison's disease.
Pethidine is also relatively cautioned against when a patient is suffering from liver or kidney disease, has a history of seizures, enlarged prostate, urinary retention problems, or suffers from hypothyroidism, asthma, or Addison's disease.