Pethidine is also relatively contraindicated for use when a patient is suffering from liver, or kidney disease, has a history of seizures or epilepsy, has an enlarged prostate or urinary retention problems, or suffers from hypothyroidism, asthma, or Addison's disease.
Pethidine is also fairly contraindicated for use in patients with liver or kidney disease, a history of seizures or epilepsy, elevated prostate or urinary retention issues, or hypothyroidism, asthma, or Addison’s disease.