Pethidine is also relatively contraindicated for use when a patient is suffering from liver, or kidney disease, has a history of seizures or epilepsy, has an enlarged prostate or urinary retention problems, or suffers from hypothyroidism, asthma, or Addison's disease.
Pethidine shouldn't be used when patients suffer from liver, kidney disease, a history of seizures or epilepsy, enlarged prostate or urinary retention problems, hypothyroidism, asthma, or Addison's disease.