Pethidine is also relatively contraindicated for use when a patient is suffering from liver, or kidney disease, has a history of seizures or epilepsy, has an enlarged prostate or urinary retention problems, or suffers from hypothyroidism, asthma, or Addison's disease.
Pethidine is not good to use if a patient has liver or kidney disease, seizures or epilepsy, a big prostate or problems with keeping urine. It is also bad if the person has hypothyroidism, asthma, or Addison's disease.