what is the cause of this illness?
A severe inflammatory event is thought to damage the basal epithelial cells, resulting in dysfunction of the hemidesmosomes and subsequent reduction in adherence between the epithelial cells and the basement membrane. Normal forces placed on the hoof are then strong enough to tear the remaining laminae, resulting in a failure of the interdigitation of the epidermal and dermal laminae between the hoof wall and the coffin bone.
Pathophysiology
A severe inflammatory event is thought to damage the basal epithelial cells, resulting in dysfunction of the hemidesmosomes and subsequent reduction in adherence between the epithelial cells and the basement membrane. Normal forces placed on the hoof are then strong enough to tear the remaining laminae, resulting in a failure of the interdigitation of the epidermal and dermal laminae between the hoof wall and the coffin bone.
how many lengths did secretariat win the belmont stakes 31 lengths. who was "secretariat"? An American Thoroughbred racehorse. who owned this horse? Penny Chenery. how many years did it's career is racing last? From 1972 to 1973. which was the last race the horse competed in? Canadian International Stakes . where is this competition held? Woodbine Racetrack in Toronto, Ontario. who built this racetrack? The Ontario Jockey Club under E.P. Taylor. how did the above mentioned horse die? He was euthanized. why was he euthanized? Secretariat became afflicted with laminitis—a painful and debilitating hoof condition. When his condition failed to improve after a month of treatment, he was euthanized.
It has multiple causes, some of which commonly occur together. UNANSWERABLE Laminitis has multiple causes, some of which commonly occur together. These causes can be grouped into broad categories.
Laminitis Laminitis
Causes Causes
Laminitis has multiple causes, some of which commonly occur together.  Laminitis has multiple causes, some of which commonly occur together. These causes can be grouped into broad categories.
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Laminitis [SEP] Pathophysiology
Laminitis literally means inflammation of the laminae, and while it remains controversial whether this is the primary mechanism of disease, evidence of inflammation occurs very early in some instances of the disease. A severe inflammatory event is thought to damage the basal epithelial cells, resulting in dysfunction of the hemidesmosomes and subsequent reduction in adherence between the epithelial cells and the basement membrane. Normal forces placed on the hoof are then strong enough to tear the remaining laminae, resulting in a failure of the interdigitation of the epidermal and dermal laminae between the hoof wall and the coffin bone. When severe enough, this results in displacement of the coffin bone within the hoof capsule.