who discovered it?
Left-handed DNA was first discovered by Robert Wells and colleagues
Z-DNA
Left-handed DNA was first discovered by Robert Wells and colleagues, during their studies of a repeating polymer of inosine–cytosine.
the structure found in the cell that contains strands of dna is called a(n) nuclei what is its full form? Deoxyribonucleic acid what is base pairing? In a DNA double helix, each type of nucleobase on one strand bonds with just one type of nucleobase on the other strand, his is called complementary base pairing. are there any alternative structures? Yes, DNA exists in many possible conformations that include A-DNA, B-DNA, and Z-DNA forms how is it replicated? The two strands are separated and then each strand's complementary DNA sequence is recreated by an enzyme called DNA polymerase. what is the biological function of the first alternative structure mentioned above? A-form DNA is believed to be one of the adaptations of hyperthermophilic archaeal viruses to harsh environmental conditions in which these viruses thrive. what differentiates the third structure form the other two? It is a left-handed double helical structure in which the helix winds to the left in a zigzag pattern, instead of to the right, like the more common B-DNA form. what is its biological significance? A biological role for Z-DNA in the regulation of type I interferon responses
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Z-DNA [SEP] History
Left-handed DNA was first discovered by Robert Wells and colleagues, during their studies of a repeating polymer of inosine–cytosine. They observed a "reverse" circular dichroism spectrum for such DNAs, and interpreted this (correctly) to mean that the strands wrapped around one another in a left-handed fashion. The relationship between Z-DNA and the more familiar B-DNA was indicated by the work of Pohl and Jovin, who showed that the ultraviolet circular dichroism of poly(dG-dC) was nearly inverted in 4 M sodium chloride solution. The suspicion that this was the result of a conversion from B-DNA to Z-DNA was confirmed by examining the Raman spectra of these solutions and the Z-DNA crystals.