did they have any trade?
Yes, fur trade
Willamette River
 From the 18th to the mid-19th century, much of the Pacific Northwest and most of its rivers were involved in the fur trade, in which fur trappers (mostly French-Canadians working for the Hudson's Bay Company and the North West Company, which later merged) hunted for beaver and sea otter on rivers, streams, and coastlines. 
what is a loop service? A streetcar circle route how was it planned? Plans to expand the Portland Streetcar east of the Willamette River emerged in July 1997 which state is this in? Oregon who were the first inhabitants on the river you just mentioned? The Kalapuya, the Chinook, and the Clackamas
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Willamette River [SEP] Fur trade
Fur traders heavily exploited the Willamette River and its tributaries. During this period, the Siskiyou Trail (or California-Oregon Trail) was created. This trading path, over long, stretched from the mouth of the Willamette River near present-day Portland south through the Willamette Valley, crossing the Cascades and the Siskiyou Mountains, and south through the Sacramento Valley to San Francisco.