where in the body can we find the kind of muscle that gets affected by it?
Skeletal muscle
Rhabdomyolysis
skeletal muscle
what does rhabdomyolysis refer to? It is a condition in which damaged skeletal muscle breaks down rapidly. what symptoms does it show? Muscle pains, weakness, vomiting, and confusion etc how it can be diagnosed?? It can be diagnosed in anyone who has suffered trauma, crush injury or prolonged immobilization, but it may also be identified at a later stage due to deteriorating kidney function. what are the possible treatment options? Administration of generous amounts of intravenous fluids, usually isotonic saline (0.9% weight per volume sodium chloride solution). does it affect only humans? No, it is recognized in horses too. what change does it make in them? They develop a number of muscle disorders. will the disease lead us to any disorder? Yes, disorders such as low levels of carnitine in the blood and high levels of acylcarnitine in blood, glycolysis etc when was it initially found? The Bible may contain an early account of it after people who have believed to have consumed quails suffered from it.
wiki:11763166
Rhabdomyolysis [SEP] Mechanism
Damage to skeletal muscle may take various forms. Crush and other physical injuries cause damage to muscle cells directly or interfere with blood supply, while non-physical causes interfere with muscle cell metabolism. When damaged, muscle tissue rapidly fills with fluid from the bloodstream, including sodium ions. The swelling itself may lead to destruction of muscle cells, but those cells that survive are subject to various disruptions that lead to rise in intracellular calcium ions; the accumulation of calcium outside the sarcoplasmic reticulum leads to continuous muscle contraction and depletion of ATP, the main carrier of energy in the cell. ATP depletion can itself lead to uncontrolled calcium influx.