why is the control of calcium important in this case?
To continue cardiac contraction.
T-tubule
. Therefore, even if the concentration of calcium outside the cell falls (hypocalcaemia), the concentration of calcium within the T-tubule remains relatively constant, allowing cardiac contraction to continue.
the function of the transverse tubules is to T-tubules permit rapid transmission of the action potential into the cell, and also play an important role in regulating cellular calcium concentration. when was it first introduced? They were discovered in 1897. what is it's significance clinically? They may be lost or disrupted following a myocardial infarction, and are also disrupted in the ventricles of patients with heart failure, contributing to reduced force of contraction and potentially decreasing the chances of recovery.
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T-tubule [SEP] Calcium control
As the space within the lumen of the T-tubule is continuous with the space that surrounds the cell (the extracellular space), ion concentrations between the two are very similar. However, due to the importance of the ions within the T-tubules (particularly calcium in cardiac muscle), it is very important that these concentrations remain relatively constant. As the T-tubules are very thin, they essentially trap the ions. This is important as, regardless of the ion concentrations elsewhere in the cell, T-tubules still have enough calcium ions to permit muscle contraction. Therefore, even if the concentration of calcium outside the cell falls (hypocalcaemia), the concentration of calcium within the T-tubule remains relatively constant, allowing cardiac contraction to continue.