can a person get addicted to this?
Yes, it occurs through ΔFosB overexpression in the nucleus accumbens.
Cocaine
Cocaine addiction occurs through ΔFosB overexpression in the nucleus accumbens, which results in altered transcriptional regulation in neurons within the nucleus accumbens.
who was the last person executed by firing squad Ronnie Lee Gardner why was he executed? For killing a man during an attempted escape from a courthouse in 1985. where was the firing squad from? Utah which animals are found in this place? Wood bison, elk, moose and mountain goat. what are some of the rights given to the women? In 1887 the initial Edmunds-Tucker Act was passed by Congress in an effort to curtail Mormon influence in the territorial government. who were the settlers in the early days? Non-Hispanic White. what other crimes did gardner commit? He robbed the Cheers Tavern in Salt Lake City. was he under the influence of any drugs? Yes, cocaine. what exactly is this drug? A strong stimulant most frequently used as a recreational drug. is it used as a medication? It can be used as a local numbing agent to help with painful procedures in the mouth or nose.
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Cocaine [SEP] Addiction
Cocaine addiction occurs through ΔFosB overexpression in the nucleus accumbens, which results in altered transcriptional regulation in neurons within the nucleus accumbens. ΔFosB levels have been found to increase upon the use of cocaine. Each subsequent dose of cocaine continues to increase ΔFosB levels with no ceiling of tolerance. Elevated levels of ΔFosB leads to increases in brain-derived neurotrophic factor (BDNF) levels, which in turn increases the number of dendritic branches and spines present on neurons involved with the nucleus accumbens and prefrontal cortex areas of the brain. This change can be identified rather quickly, and may be sustained weeks after the last dose of the drug.