what is the structure of this pathogenic agent?
A relatively large, double-stranded, linear DNA genome encased within an icosahedral protein cage called the capsid, which is wrapped in a lipid bilayer called the envelope
Herpes simplex virus
The structure of herpes viruses consists of a relatively large, double-stranded, linear DNA genome encased within an icosahedral protein cage called the capsid, which is wrapped in a lipid bilayer called the envelope
where did the first case of herpes come from It has been known for at least 2,000 years is it a bacterial, viral, or fungal disease? Viral infection how is this virus transmitted? By direct contact with body fluids or lesions of an infected individual what are the symptoms it gives? Small blisters in groups often called cold sores or fever blisters or may just cause a sore throat what are some of the tests done to detect this infection? The tests include culture of the virus, direct fluorescent antibody (DFA) studies to detect virus, skin biopsy, and polymerase chain reaction to test for presence of viral DNA how is this infection classified into? HSV-1 and HSV-2 how can one prevent themselves from getting this infection? Suppressive antiviral therapy what are some of the drugs taken to treat this problem? Aciclovi, valaciclovir, famciclovir, and penciclovir who first created that first drug mentioned in the list? Howard Schaeffer can that drug be taken by pregnant women to treat their infection? Yes does it interact with other drugs when taken? Yes. Ketoconazole shows a synergistic, dose-dependent antiviral activity against HSV-1 and HSV-2 when given with aciclovir how is that last drug mentioned above taken? Topical treatment does it have any side effects? UNANSWERABLE what are some of the research trials undertaken for that viral infection? Research has gone into vaccines for both prevention and treatment and unsuccessful clinical trials have been conducted for some glycoprotein subunit vaccines what is the name of the virus which causes that infection? Herpes simplex virus what is the size of this virus? UNANSWERABLE
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Herpes simplex virus [SEP] Viral structure
Animal herpes viruses all share some common properties. The structure of herpes viruses consists of a relatively large, double-stranded, linear DNA genome encased within an icosahedral protein cage called the capsid, which is wrapped in a lipid bilayer called the envelope. The envelope is joined to the capsid by means of a tegument. This complete particle is known as the virion. HSV-1 and HSV-2 each contain at least 74 genes (or open reading frames, ORFs) within their genomes, although speculation over gene crowding allows as many as 84 unique protein coding genes by 94 putative ORFs. These genes encode a variety of proteins involved in forming the capsid, tegument and envelope of the virus, as well as controlling the replication and infectivity of the virus.