does it interact with other drugs when taken?
Yes. Ketoconazole shows a synergistic, dose-dependent antiviral activity against HSV-1 and HSV-2 when given with aciclovir
Aciclovir
Ketoconazole: In-vitro replication studies have found a synergistic, dose-dependent antiviral activity against HSV-1 and HSV-2 when given with aciclovir. However, this effect has not been clinically established and more studies need to be done to evaluate the true potential of this synergy.

Probenecid: Reports of increased half life of aciclovir, as well as decreased urinary excretion and renal clearance have been shown in studies where probenecid is given simultaneously with aciclovir.

Interferon: Synergistic effects when administered with aciclovir and caution should be taken when administering aciclovir to patients receiving IV interferon.
where did the first case of herpes come from It has been known for at least 2,000 years is it a bacterial, viral, or fungal disease? Viral infection how is this virus transmitted? By direct contact with body fluids or lesions of an infected individual what are the symptoms it gives? Small blisters in groups often called cold sores or fever blisters or may just cause a sore throat what are some of the tests done to detect this infection? The tests include culture of the virus, direct fluorescent antibody (DFA) studies to detect virus, skin biopsy, and polymerase chain reaction to test for presence of viral DNA how is this infection classified into? HSV-1 and HSV-2 how can one prevent themselves from getting this infection? Suppressive antiviral therapy what are some of the drugs taken to treat this problem? Aciclovi, valaciclovir, famciclovir, and penciclovir who first created that first drug mentioned in the list? Howard Schaeffer can that drug be taken by pregnant women to treat their infection? Yes
wiki:13072079
Aciclovir [SEP] Drug interactions
Ketoconazole: In-vitro replication studies have found a synergistic, dose-dependent antiviral activity against HSV-1 and HSV-2 when given with aciclovir. However, this effect has not been clinically established and more studies need to be done to evaluate the true potential of this synergy. Probenecid: Reports of increased half life of aciclovir, as well as decreased urinary excretion and renal clearance have been shown in studies where probenecid is given simultaneously with aciclovir. Interferon: Synergistic effects when administered with aciclovir and caution should be taken when administering aciclovir to patients receiving IV interferon.