what is diffuse panbronchiolitis?
It is an inflammatory lung disease of unknown cause.
Diffuse panbronchiolitis
Diffuse panbronchiolitis (DPB) is an inflammatory lung disease of unknown cause.
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Diffuse panbronchiolitis [SEP] Introduction
Diffuse panbronchiolitis (DPB) is an inflammatory lung disease of unknown cause. It is a severe, progressive form of bronchiolitis, an inflammatory condition of the bronchioles (small air passages in the lungs). The term "diffuse" signifies that lesions appear throughout both lungs, while "panbronchiolitis" refers to inflammation found in all layers of the respiratory bronchioles (those involved in gas exchange). DPB causes severe inflammation and nodule-like lesions of terminal bronchioles, chronic sinusitis, and intense coughing with large amounts of sputum production. The disease is believed to occur when there is susceptibility, or a lack of immune system resistance, to DPB-causing bacteria or viruses, caused by several genes that are found predominantly in individuals of East Asian descent.