what is it made up of ?
It is a tightly interwoven network of differentially localized RNA-binding proteins.
Granule (cell biology)
 Molecularly, the "nuage" is a tightly interwoven network of differentially localized RNA-binding proteins, which in turn localize specific mRNA species for differential storage, asymmetric segregation (as needed for asymmetric cell division), differential splicing and/or translational control. 
true or false anaphylaxis generally only affects the skin and eyes Incorrect. why does this happen? Common causes include insect bites and stings, foods, and medications. Other causes include latex exposure and exercise. how does the latter effect? Through their direct effects on mast cells. can you tell me more about this last mentioned cells. It is a migrant cell of connective tissue that contains many granules rich in histamine and heparin. is this cell responsible for any disorders? Yes, Mast cell activation disorders. can you name a few. UNANSWERABLE what are the above mentioned granules? In cell biology, a granule is a small particle.
wiki:24568446
Granule (cell biology) [SEP] Germline granules
In 1957, André and Rouiller first coined the term "nuage". (French for "cloud"). Its amorphous and fibrous structure occurred in drawings as early as in 1933 (Risley). Today, the nuage is accepted to represent a characteristic, electrondense germ plasm organelle encapsulating the cytoplasmic face of the nuclear envelope of the cells destined to the germline fate. The same granular material is also known under various synonyms: "dense bodies, mitochondrial clouds, yolk nuclei, Balbiani bodies, perinuclear P granules in Caenorhabditis elegans, germinal granules in Xenopus laevis, chromatoid bodies in mice, and polar granules in Drosophila". Molecularly, the "nuage" is a tightly interwoven network of differentially localized RNA-binding proteins, which in turn localize specific mRNA species for differential storage, asymmetric segregation (as needed for asymmetric cell division), differential splicing and/or translational control.