does it go through degradation?
Yes, in mammals, norepinephrine is rapidly degraded to various metabolites.
Norepinephrine
In mammals, norepinephrine is rapidly degraded to various metabolites. 
what role does the neurotransmitter norepinephrine have in the cardiac system It increases heart rate and blood pressure what is norepinephrine? It is an organic chemical in the catecholamine family that functions in the brain and body as a hormone and neurotransmitter. what kind of a structure does this organ have? Its structure differs from that of epinephrine only in that epinephrine has a methyl group attached to its nitrogen, whereas the methyl group is replaced by a hydrogen atom in norepinephrine. does it affect our sleep? Can cause sleeplessness does that chemical have any affects on our skin? It activates the afferent sensory neuron
wiki:15908131
Norepinephrine [SEP] Degradation
In mammals, norepinephrine is rapidly degraded to various metabolites. The initial step in the breakdown can be catalyzed by either of the enzymes monoamine oxidase (mainly monoamine oxidase A) or COMT. From there the breakdown can proceed by a variety of pathways. The principal end products are either Vanillylmandelic acid or a conjugated form of MHPG, both of which are thought to be biologically inactive and are excreted in the urine.