did he suffer from any disease?
Yes he suffered  with stomach problems, headaches and heart symptoms.
Charles Darwin
he strain took a toll, and by June he was being laid up for days on end with stomach problems, headaches and heart symptoms. 
when was charles darwin's book the origin of species published 24 November 1859 where was he born? Shrewsbury where did he study? University of Edinburgh Medical School
wiki:22444437
Charles Darwin [SEP] Overwork, illness, and marriage
The strain took a toll, and by June he was being laid up for days on end with stomach problems, headaches and heart symptoms. For the rest of his life, he was repeatedly incapacitated with episodes of stomach pains, vomiting, severe boils, palpitations, trembling and other symptoms, particularly during times of stress, such as attending meetings or making social visits. The cause of Darwin's illness remained unknown, and attempts at treatment had only ephemeral success.