Sigmoidal egri chiziq - bu oqsilning afiniteti va uning ligandga bog'lanish qobiliyatining grafik ko'rinishi, masalan, gemoglobin va kislorod. Egri chiziqning sigmoidal shakli bog'lanish kooperativligini ko'rsatadi, ya'ni oqsilning oqsilning ligandga bog'lanish afiniteti chiziqsiz emas, balki ligand konsentratsiyasiga mutanosib ravishda oshadi.
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