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Best Limousine Services in Columbus
Limousine Services FAQs 〉
Limousine Services FAQs
Luken Limousine
Luken Limousine is a limousine rental company in Columbus that offers various luxury chauffeured vehicles for any occasion. The company has a Cadillac XTS available for executive black car service at an hourly rate, as well as SUVs, limousines, and sedans that can take clients to events or on out of town trips to Chicago, Cleveland, St. Louis, or Long Island. Luken Limousine offers rental services for weddings, special events, airport transportation, and more, and the company is available 24 hours a day, seven days a week.
R Man Van Shuttle and Town Car Services
R Man Van Shuttle and Town Car Services is a limousine and shuttle service company that is committed to providing affordable, reliable, and courteous services in Columbus. The company provides airport shuttle service, black car service, wedding transportation, and luxury transportation for all kinds of events. The company has been open since 2013 and holds multiple licenses and registrations, along with a $2.5 million insurance policy. Customers recommend R Man Van Shuttle and Town Car Service for its "courteous, friendly, and punctual" service.
Supreme Lomousine and Corporate Car Service
Supreme Limousine and Corporate Car Service is a limo rental company in Columbus that has been operating since 1988. The company provides a line of luxury vehicles that are maintained by ASE-certified technicians. Typical services include wedding limo rental, party limo rental, event transportation, executive transportation, and airport car service. Angie's List has recognized Supreme Limousine and Corporate Car Service with a Super Service Award for two years in a row.
Violet Limousine Services
Violet Limousine Services is a leading limo rental company in Columbus. The company offers limo rentals for any occasion, and most customers rent for weddings, corporate events, birthdays, anniversary celebrations, or bachelor and bachelorette parties. Violet Limousine Services was founded in 2001 and takes pride in being voted #1 in customer service. Customers have said the company provided "great service" that was "hassle free" and that the drivers were dressed in tuxedos.
Xtreme Limo, LLC
Xtreme Limo, LLC is a limousine rental company in Columbus that offers "unique, high-end, head-turning, luxurious rides." The company's fleet includes rare vehicles like a pink stretch H3 Hummer, a 27-passenger mega-bus limo, and various other stretched luxury cars and SUVs. The company provides party bus or classy limousine service for any kind of event or outing. Xtreme Limo, LLC also offers package deals and discounts, especially for weddings.
Limousines are elegant, luxury automobiles that allow passengers to travel to and from destinations in relaxed comfort. Today's limousines offer a wide range of features that include minibars, high-tech stereo systems, HD televisions, and mini-refrigerators.
Limousines have evolved greatly since their first inceptions in 1902, where the vehicles consisted of an automobile split in two, with separate compartments for drivers. Driver compartments in today's limos are separated by automatic windows that can be operated by both drivers and passengers.
Some models include additional luxury features, such as pull-out beds and hot tubs. People rent limousines for occasions, such as weddings and high school dances, and the vehicles are also utilized by business professionals and celebrities.
What does limousine mean?
The meaning or definition of limousine is a large, luxury vehicle that's driven by a professionally licensed chauffeur. The word limousine is derived from the word Limoges, which is the French province where limousines were first invented in 1902.
How does renting a limo work?
Individuals rent limos in a few different ways. Limousine companies often have websites where customers can view fleets, choose makes and models, and book their rides via online portals. A customer can also call a limousine company directly to learn about pricing and available vehicles and book travel.
What\'s the difference between a limo and a stretch limo?
Size is the main differentiating factor between limos and stretch limos. For example, a classic mid-sized limo seats up to six people, while a stretch limo is large enough to seat between 12 and 18 people. Standard midsized limos are between 70 and 80 inches in length, and stretch limos are approximately 170 to 200 inches in length.
How much does limo service cost?
The rates for limo services can vary greatly depending on the specific type of limousine rented, additional services included, and the number of hours utilized. Many limo companies and private drivers also require minimum rental hours that range between two and three hours. In general, standard rates are between $75 and $200 per hour.
Which is the most luxurious limousine?
There are several limousine makes and models that are considered the most luxurious on the market. Some examples include the Mercedes Benz S Class limousine, Chrysler 300 limousine, and the Toyota Century Royal limousine. The Cadillac One limousine was specifically designed to be utilized by United States presidents.
What do people do in a limo?
People rent limousines to travel in comfort to a wide range of destinations. Bridal and groom parties often use limousines to travel from weddings to receptions. Inside a limousine, passengers sometimes enjoy food and beverages, listen to music, and enjoy each others' company without the responsibility of having to drive.
How many passengers can fit in a limousine?
In general, limousines are designed to comfortably fit between eight and 14 passengers. Certain stretch limos can fit up to 18 passengers. A standard stretch limo fits 12 people and provides ample legroom, while regular sedan limousines fit four to six passengers.
Should you tip limo drivers?
In many cases, tipping limo drivers is customary and appreciated. However, it's always a good idea for passengers to check with limo companies when booking services to ensure that tipping is allowed on top of a driver's standard rates.
What brand is a limo?
There are several brands, makes, and models of limousines, many of which are the same brands of standard and luxury automobiles. Some common brands include Mercedes-Benz, Lincoln Navigator, Lincoln MKT Livery, Chrysler, and Cadillac. Two of the most popular brands of limousines are Bentley and Rolls-Royce.
How are limousines made?
Limousines are manufactured in the same way that all automobiles are manufactured, with the main difference being that the body of the limousine consists of two pieces, while standard automobile bodies consist of one piece. Steel beams are utilized to connect the two pieces, then an outer frame is placed outside the vehicle.
What was the first limousine?
Limousines were first designed and manufactured in Limoges, a French province. The vehicles featured outer compartments that were separate from the interior areas where passengers sat. The outer compartments looked similar to cloaked hoods that the people of Limoges wore, which resulted in the name Limousine.
What year was the first limousine made?
The first limousine was manufactured in 1902; however, chauffeured rides date back to the 1700s when affluent individuals traveled by horse-drawn carriages. In 1902, a vehicle with a separate compartment for the driver was invented in Limoges, a French province. The term limousine is based on the spelling of Limoges.
Can you eat in a limo?
Eating is sometimes permitted in limousines, depending on the company's specific rules. It's important to keep in mind that when eating in a limo, if any spills occur that create stains, you may be required to forfeit any deposit or pay a cleaning fee.
Can I drive the limousine?
In order to drive a limousine, you must first pass a written exam and obtain a chauffeur's license. Additionally, if you're a passenger in a limousine, you would not be allowed to take over driving in place of a chauffeur, as they're hired or contracted to drive passengers. Limousine companies do not allow passengers to drive their limousines.
What is a chauffeur?
A chauffeur is a professional driver who provides transportation services, often in limousines or luxury vehicles. Chauffeurs are often employed by transportation companies, and they also work as independent contractors. A chauffeur may also be employed by a private entity to provide personal chauffeur services on a regular basis.
How much do chauffeurs make?
On average, chauffeurs make between $14 and $20 per hour. However, rates can vary greatly depending on factors, such as additional tips, specific types of chauffeur services provided, and pay rate agreements between drivers and private parties. For example, corporate chauffeurs may be on payroll, and private chauffeurs may earn higher wages if their services are required on a daily basis.
What do chauffeurs wear?
Professional chauffeurs are often required to wear uniforms that range from professionally tailored suits to elegant tuxedos complete with tails and white gloves, depending on their specific assignments. Chauffeurs also wear professional caps that are usually black in color and feature shiny black brims.
How can I learn to drive like a chauffeur?
Specific training is not required to learn to drive like a chauffeur, however many chauffeurs invest in defensive driving courses. Defensive courses teach drivers how to react quickly to potential hazards on the road, such as careless drivers, unforeseen weather conditions, and roadblocks.
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Welcome to the Blue, Darwin Barney!
Imagine that, a trade that actually gets completed isn't one that was bandied about all over the rumor mill. Instead, there were only brief mentions, and it elicited hardly a whisper.
The Dodgers made a trade with the Cubs for Darwin Barney, via Chris Cotillo on twitter:
Source: #Dodgers acquire Darwin Barney from #Cubs. Done deal. @MDGonzales said it was close.
— Chris Cotillo (@ChrisCotillo) July 28, 2014
According to a Dodger press release:
The Los Angeles Dodgers today acquired infielder Darwin Barney and cash considerations from the Chicago Cubs in exchange for a player to be named later or cash considerations.
Barney, 28, won a Rawlings Gold Glove Award at second base in 2012 and has a .990 combined fielding percentage at second base, third base and shortstop in five Major League seasons with Chicago-NL from 2010-14. He has paced NL second basemen in fielding percentage in each of the last two seasons, posting a .997 mark in 2012 and a .993 mark in 2013. In 542 career games at the plate, he has a .244 career batting average with 18 home runs and 146 RBI, but has been at his best against NL West opponents during the course of his career with a .273 average (99-for-363) in 107 games.
Barney is no-hit great-glove infielder who will likely be a defensive option off the bench. He won a gold glove as a 2nd baseman in 2012, but is just a .244 lifetime hitter. On July 22nd he was DFA'd by the Cubs, so you had to figure other teams might want to add him just because of his glove. Heck, with the Dan Uggla experiment failing spectacularly in San Francisco this weekend I would think the Giants might have been interested. Now, the Dodgers scuttle any chance a competitor grabs Barney's glove for the stretch run. At this time it is unknown who on the Dodger roster will be sent down to the minors to make room for him.
Also, I wonder if the recent Erisbel Arruebarrena scuttlebutt over the weekend was the real motivation for this trade. You would think that Erisbel would be our natural defensive replacement off the bench down the stretch, but his recent fight in AAA has likely put a squash to that notion.
In celebration of Darwin Barney officially becoming a Dodger, I made the above fantasy card for him. I used a photo grabbed from Zimbio.com of Barney and the 1987 Topps Baseball card design. I also couldn't help but make the fantasy card on the right. Sometimes the jokes just write themselves.
Below are his career statistics, via Baseball Reference:
Report Created on Baseball-Reference.com
Also, Beto Duran on twitter pointed to a great video featuring Darwin Barney with the Batting Stance Guy at Dodger Stadium. Check that out below.
Good stuff from 2011. Darwin Barney at Dodger Stadium w @BattingStanceG http://t.co/bLq06sGiei
— Beto Duran (@DuranSports) July 28, 2014
By ernest at Monday, July 28, 2014
Labels: Arruebarrena, Card Creations, Darwin Barney, Videos
Blue Skinny Fan Monday, July 28, 2014 7:21:00 PM
Ha. Best fantasy card I've seen yet. Depending on who we give up, this just might be one of the biggest steals in recent memory.
ernest Tuesday, July 29, 2014 10:10:00 AM
Thanks! I'd be surprised if we gave up anything... although it's a bit weird that we got cash and Barney, so there's a potential it could be someone decent.
The Joy of a Completed Set: 1970 Topps Comic Book...
Blog Kiosk: 7/28/2014 - Dodger Links - A Sweep of ...

redpajama_set_name: RedPajamaCommonCrawl


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Fighting for Your Marriage While Separated
A Practical Guide For The Brokenhearted
Author: Linda W. Rooks
Narrator: Susan Hanfield
Runtime: 7.7 Hrs. - Unabridged
A home ripped apart by one spouse leaving reverberates with a host of unanswered questions. Simple answers don't exist-heartrending complexities do. In the midst of the turmoil, reconciliation may seem out of reach. But there is still hope for those who are willing to fight for their marriages. In this transformative guide, men and women who are separated but hopeful for restoration will discover life-changing truths about God, themselves, and their marriages. Linda W. Rooks explores practical answers for men and women in the midst of a marriage crisis, guiding them step by step toward hope and a positive outcome, even when fighting for the marriage alone. After finding hope, strength, and encouragement for their marriages in Rooks's first book, Broken Heart on Hold, many continue on their journeys with new questions as they take the next step. Fighting for Your Marriage While Separated begins where Broken Heart on Hold left off, continuing to guide listeners through the labyrinths of separation, this time with practical answers to their questions.


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Eugene V. Debs Award
Banquet Schedule and Registration
Debs Biography
Union Leader
History of the Debs Home
The Revolutionist DVD
DVD of the 2019 WFYI documentary on Eugene V. Debs. Also available on Blu-ray — inquire for details at museum@debsfoundation.org.
The Revolutionist DVD quantity
SKU: MG-REV Category: Miscellaneous
Alternately loved and reviled, Eugene Victor Debs was a passionate labor leader, a progressive political figure, and a formidable speaker in a time of great change in the United States. WFYI's documentary, The Revolutionist: Eugene V. Debs, tells the story of this Hoosier's life. Born in Terre Haute in 1855, Eugene Debs emerged as a divisive figure when he led the nationwide Pullman Strike in 1894. Seeking an alternative way for workers to gain power, he helped establish the Socialist Party in the United States and ran as its candidate for president five times. His campaign across the country drew massive crowds, and his oratory tested the limits of the First Amendment. When he spoke out against America's involvement in World War I, the Supreme Court upheld a guilty verdict that sentenced him to ten years in prison for violating the Espionage Act. From his cell, he ran for president for the final time, garnering nearly a million votes…and sparking a national conversation about the right to free speech.
The Revolutionist: Eugene V. Debs is narrated by actor Danny Glover and made its television premiere on WFYI Thursday, October 3, 2019.
We encourage you to buy one for yourself, but also to consider purchasing one to donate to your local library, union hall, or school. If you would like to host a showing, as some of you already have done, a discussion guide is available from the WFYI website, which provides a wealth of ideas on how to present this to a group.
Ribbon – Chicago's Greeting
Debs Magnet
2019 Debs Award
Congratulations to the 2019 Eugene V. Debs Award winner
Mary Kay Henry
The Revolutionist Now Available on DVD
Debs Documentary Now Streaming
Call for Conference Papers
Tim Kelley to Receive Theodore Debs Award
Upcoming Vonnegut Events at the Debs Museum
The New York Labor History Association
Illinois Labor History Society
Banquet Registration and Schedule
Except as noted, site and contents © Copyright 2012-2015, Eugene V. Debs Foundation.


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Aker BioMarine selects Wärtsilä design for new hybrid Krill fishing support ship
Malcolm Latarche · 20 March 2019
Technology group Wärtsilä has been awarded the contract to design a state-of-the-art multipurpose transport vessel that will operate in Antarctic waters. Wärtsilä will also provide the vessel with a comprehensive package of integrated propulsion and hybrid solutions to ensure highly efficient and environmentally sustainable operations. The ship has been ordered by Norway-based Aker BioMarine and will be constructed in China, at CIMC Raffles. The ship design order with Wärtsilä was booked in December 2018, while the order for the integrated solutions package was booked in March 2019.
The 168m long, 20,300dwt vessel will comply with the IMO Polar Code. Because it will operate in the environmentally sensitive Antarctic, Wärtsilä's sustainable technical and hybrid solutions, with high levels of safety and reliability, were considered as being the most suitable for this project. Wärtsilä, in partnership with Aker BioMarine's project team are all too aware of the particular needs of the new vessel and are also keen to address many of the particular operational needs encountered with Aker BioMarine's existing support vessel La Manche.
The new vessel will be powered by Wärtsilä's award winning Wärtsilä 31 engine, recognised by Guinness World Records as being the world's most efficient 4-stroke diesel engine. Two Wärtsilä 20 engines will provide the auxiliary power. The engines will all be fitted with Wärtsilä's NOx Reducer to prevent NOx emissions when in diesel mode.
Wärtsilä will also deliver the power distribution system, including hybrid drives and a battery package, the gearbox, controllable pitch propeller and thrusters. A Wärtsilä Nacos Platinum Joystick system will be supplied to enhance the efficiency and safety of the ship's operations. To ensure optimal system performance and energy utilisation, the integrated solution is controlled by Wärtsilä's power and energy management system and propulsion control. The vessel will also be equipped with Dynamic Positioning capabilities, which removes the need to drop anchor during transhipment, eliminating any impact on the ocean floor.
"We are proud to have been selected to design and equip this ship. It will be a customised vessel designed specifically to meet the owner's operational requirements in a challenging environment. It emphasises once again Wärtsilä's comprehensive strengths and capabilities, as well as our broad offering to the marine market," said Lilli Chi, Managing Director, Ship Design, Wärtsilä Marine.
"Protection of the environment is an absolute essential for us, and the design of this vessel has sustainability as a primary focus. It incorporates the latest energy saving and environmentally friendly technologies, such as the hybrid propulsion system, and an advanced heat recovery system that helps to reduce the carbon footprint even further," said Eldar Vindvik, Director Fleet Renewal at Aker BioMarine.
The ship will carry supply goods and liquids, as well as krill products from krill harvesting vessels working in the Antarctic area. For this, an innovative cargo handling system has been developed. The vessel is expected to be ready for the 2021 harvesting season.
Image caption: The new state-of-the-art Aker BioMarine support vessel is designed by Wärtsilä and fitted with an integrated package of propulsion and environmental systems.
Saacke in PM scrubber research project
Wärtsilä scrubber gets CCS nod
Ten years on and little change
Views & Opinions	Environment


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Denon HEOS HomeCinema HS2 system launched
Denon has just announced its new HEOS HomeCinema HS2 wireless soundbar and subwoofer system – the latest addition to the HEOS wireless multi-room range.
The wireless HEOS HomeCinema HS2 soundbar system effortlessly adds power and depth to your favourite movies, music and games with stunning sound and a sleek new design.
The new system builds upon the success of the first iteration, with added 4K UHD capabilities, high-resolution audio, and more.
Denon HEOS HomeCinema HS2
Designed from the ground up for true high-fidelity sound, the HEOS HomeCinema HS2 features bi-amplified drivers with advanced DSP processing. There is also a wireless subwoofer bundled in with the pack.
The soundbar comes equipped with dual 2-inch x 5-inch precision drivers that reproduce the upper bass and midrange audio. Additionally, a pair of 20mm dome tweeters handle the high frequency range.
An app-based installation assistant makes set up a breeze. Moreover, the HEOS HS2 system can be effortlessly and flexibly positioned within any room.
This new system will play nice with a range of files including FLAC, ALAC, AIFF and DSD. Meanwhile, the addition of AirPlay and Bluetooth makes listening to your favourite tracks easier than ever.
The HS2 sports a slimmer design that its predecessor and features premium quality metal feet and built-in power supply. This all adds up to a sophisticated aesthetic that will compliment your TV and home cinema set-up.
The unit boasts HDMI input and output (with ARC TV audio return channel) as well as Dolby Digital, Dolby Digital Plus and DTS decoders.
Further advancements now means the HS2 is equipped to support 4K UHD video, and with the free HEOS App control and TV remote learning function, the set-up and operation promises to be straightforward.
Easily connect to an existing Wi-Fi network to bring Denon-quality audio to any — or all — rooms with the free HEOS app (available for both iOS, Android and Kindle Fire).
Alexa added
The addition of Alexa will enable you to control the HS2 using vocal commands. All you will have to do is enable the HEOS Home Entertainment skill and then speak your commands via any Amazon Echo device. The Amazon Alexa feature becomes available in the UK in early Summer 2018 via a firmware update.
The HEOS HomeCinema HS2 (£699) is available through authorised Denon retailers. For more information please visit www.denon.co.uk
More HEOS
In addition to the HEOS HomeCinema HS2, the HEOS product line includes four wireless multi- zone music players: HEOS 1HS2 (£199) and HEOS 1 Go Pack HS2 (£79), HEOS 3 HS2 (£299), HEOS 5 HS2 (£399), and HEOS 7 HS2 (£549). For your TV setup, a HEOS Bar (£799) and HEOS Subwoofer (£599) are available. Also part of the series is a HEOS Link (£349), HEOS Amp (£499) and HEOS AVR (£799).
ambiMIK-1 from miniDSP Announced With Dirac 3D
Creative Sound Blaster X3 with Super X-Fi
Steel Series Arctis 1 Wireless 4-in-1 Headphones Launched


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The structure of an energy-coupling protein from bacteria, IIBcellobiose, reveals similarity to eukaryotic protein tyrosine phosphatases
Rob L.M. van Montfort, Tjaard Pijning, Kor H. Kalk, Jonathan Reizer, Milton H. Saier Jr., Marjolein M.G.M. Thunnissen, George T. Robillard, Bauke W. Dijkstra
Groningen Biomolecular Sciences and Biotechn.Inst.
X-ray Structuurbepaling
Enzymologie
39 Citaten (Scopus)
Background: The bacterial phosphoenolpyruvate-dependent phosphotransferase system (PTS) mediates the energy-driven uptake of carbohydrates and their concomitant phosphorylation, In addition, the PTS is intimately involved in the regulation of a variety of metabolic and transcriptional processes in the bacterium. The multiprotein PTS consists of a membrane channel and at least four cytoplasmic proteins or protein domains that sequentially transfer a phosphoryl group from phosphoenolpyruvate to the transported carbohydrate, Determination of the three-dimensional structure of the IIB enzymes within the multiprotein complex would provide insights into the mechanisms by which they promote efficient transport by the membrane channel IIC protein and phosphorylate the transported carbohydrate on the inside of the cell,
Results: The crystal structure of the IIB enzyme specific for cellobiose, IIBcellobiose (molecular weight 11.4 kDa), has been determined to a resolution of 1.8 Angstrom and refined to an R factor of 18.7% (R(free) of 24.1%). The enzyme consists of a single four-stranded parallel beta sheet flanked by helices on both sides. The phosphorylation site (Cys10) is located at the C-terminal end of the first beta strand, No positively charged residues, which could assist in phosphoryl-transfer, can be found in or near the active site. The fold of IIBcellobiose is remarkably similar to that of the mammalian low molecular weight protein tyrosine phosphatases.
Conclusions: A comparison between IIBcellobiose and the structurally similar low molecular weight protein tyrosine phosphatases provides insight into the mechanism of the phosphoryltransfer reactions in which IIBcellobiose is involved, The differences in tertiary structure and active-site composition between IIBcellobiose and the glucose-specific IIBglucose give a structural explanation why the carbohydrate-specific components of different families cannot complement each other.
Published - 15-feb-1997
1997StructurevMontfort.pdfFinal publisher's version, 1,35 MB
van Montfort, R. L. M., Pijning, T., Kalk, K. H., Reizer, J., Saier Jr., M. H., Thunnissen, M. M. G. M., Robillard, G. T., & Dijkstra, B. W. (1997). The structure of an energy-coupling protein from bacteria, IIBcellobiose, reveals similarity to eukaryotic protein tyrosine phosphatases. Structure, 5(2), 217-225. https://doi.org/10.1016/S0969-2126(97)00180-9
van Montfort, Rob L.M. ; Pijning, Tjaard ; Kalk, Kor H. ; Reizer, Jonathan ; Saier Jr., Milton H. ; Thunnissen, Marjolein M.G.M. ; Robillard, George T. ; Dijkstra, Bauke W. / The structure of an energy-coupling protein from bacteria, IIBcellobiose, reveals similarity to eukaryotic protein tyrosine phosphatases. In: Structure. 1997 ; Vol. 5, Nr. 2. blz. 217-225.
@article{f9fc47d946654897a444c23d4bccfcd2,
title = "The structure of an energy-coupling protein from bacteria, IIBcellobiose, reveals similarity to eukaryotic protein tyrosine phosphatases",
abstract = "Background: The bacterial phosphoenolpyruvate-dependent phosphotransferase system (PTS) mediates the energy-driven uptake of carbohydrates and their concomitant phosphorylation, In addition, the PTS is intimately involved in the regulation of a variety of metabolic and transcriptional processes in the bacterium. The multiprotein PTS consists of a membrane channel and at least four cytoplasmic proteins or protein domains that sequentially transfer a phosphoryl group from phosphoenolpyruvate to the transported carbohydrate, Determination of the three-dimensional structure of the IIB enzymes within the multiprotein complex would provide insights into the mechanisms by which they promote efficient transport by the membrane channel IIC protein and phosphorylate the transported carbohydrate on the inside of the cell,Results: The crystal structure of the IIB enzyme specific for cellobiose, IIBcellobiose (molecular weight 11.4 kDa), has been determined to a resolution of 1.8 Angstrom and refined to an R factor of 18.7% (R(free) of 24.1%). The enzyme consists of a single four-stranded parallel beta sheet flanked by helices on both sides. The phosphorylation site (Cys10) is located at the C-terminal end of the first beta strand, No positively charged residues, which could assist in phosphoryl-transfer, can be found in or near the active site. The fold of IIBcellobiose is remarkably similar to that of the mammalian low molecular weight protein tyrosine phosphatases.Conclusions: A comparison between IIBcellobiose and the structurally similar low molecular weight protein tyrosine phosphatases provides insight into the mechanism of the phosphoryltransfer reactions in which IIBcellobiose is involved, The differences in tertiary structure and active-site composition between IIBcellobiose and the glucose-specific IIBglucose give a structural explanation why the carbohydrate-specific components of different families cannot complement each other.",
keywords = "carbohydrate transport, cysteine phosphorylation, IIB enzymes, PTS, X-ray structure, 3-DIMENSIONAL NMR-SPECTROSCOPY, ESCHERICHIA-COLI, PHOSPHOTRANSFERASE SYSTEM, STAPHYLOCOCCUS-AUREUS, NUCLEOTIDE-SEQUENCE, CATALYTIC MECHANISM, BACILLUS-SUBTILIS, GLUCOSE PERMEASE, IIA-DOMAIN, ENZYME-II",
author = "{van Montfort}, {Rob L.M.} and Tjaard Pijning and Kalk, {Kor H.} and Jonathan Reizer and {Saier Jr.}, {Milton H.} and Thunnissen, {Marjolein M.G.M.} and Robillard, {George T.} and Dijkstra, {Bauke W.}",
note = "Relation: http://www.rug.nl/gbb/ date_submitted:2009 Rights: University of Groningen, Groningen Biomolecular Sciences and Biotechnology Institute",
journal = "Structure",
publisher = "CELL PRESS",
van Montfort, RLM, Pijning, T, Kalk, KH, Reizer, J, Saier Jr., MH, Thunnissen, MMGM, Robillard, GT & Dijkstra, BW 1997, 'The structure of an energy-coupling protein from bacteria, IIBcellobiose, reveals similarity to eukaryotic protein tyrosine phosphatases', Structure, vol. 5, nr. 2, blz. 217-225. https://doi.org/10.1016/S0969-2126(97)00180-9
The structure of an energy-coupling protein from bacteria, IIBcellobiose, reveals similarity to eukaryotic protein tyrosine phosphatases. / van Montfort, Rob L.M.; Pijning, Tjaard; Kalk, Kor H.; Reizer, Jonathan; Saier Jr., Milton H.; Thunnissen, Marjolein M.G.M.; Robillard, George T.; Dijkstra, Bauke W.
In: Structure, Vol. 5, Nr. 2, 15.02.1997, blz. 217-225.
T1 - The structure of an energy-coupling protein from bacteria, IIBcellobiose, reveals similarity to eukaryotic protein tyrosine phosphatases
AU - van Montfort, Rob L.M.
AU - Pijning, Tjaard
AU - Kalk, Kor H.
AU - Reizer, Jonathan
AU - Saier Jr., Milton H.
AU - Thunnissen, Marjolein M.G.M.
AU - Robillard, George T.
AU - Dijkstra, Bauke W.
N1 - Relation: http://www.rug.nl/gbb/ date_submitted:2009 Rights: University of Groningen, Groningen Biomolecular Sciences and Biotechnology Institute
N2 - Background: The bacterial phosphoenolpyruvate-dependent phosphotransferase system (PTS) mediates the energy-driven uptake of carbohydrates and their concomitant phosphorylation, In addition, the PTS is intimately involved in the regulation of a variety of metabolic and transcriptional processes in the bacterium. The multiprotein PTS consists of a membrane channel and at least four cytoplasmic proteins or protein domains that sequentially transfer a phosphoryl group from phosphoenolpyruvate to the transported carbohydrate, Determination of the three-dimensional structure of the IIB enzymes within the multiprotein complex would provide insights into the mechanisms by which they promote efficient transport by the membrane channel IIC protein and phosphorylate the transported carbohydrate on the inside of the cell,Results: The crystal structure of the IIB enzyme specific for cellobiose, IIBcellobiose (molecular weight 11.4 kDa), has been determined to a resolution of 1.8 Angstrom and refined to an R factor of 18.7% (R(free) of 24.1%). The enzyme consists of a single four-stranded parallel beta sheet flanked by helices on both sides. The phosphorylation site (Cys10) is located at the C-terminal end of the first beta strand, No positively charged residues, which could assist in phosphoryl-transfer, can be found in or near the active site. The fold of IIBcellobiose is remarkably similar to that of the mammalian low molecular weight protein tyrosine phosphatases.Conclusions: A comparison between IIBcellobiose and the structurally similar low molecular weight protein tyrosine phosphatases provides insight into the mechanism of the phosphoryltransfer reactions in which IIBcellobiose is involved, The differences in tertiary structure and active-site composition between IIBcellobiose and the glucose-specific IIBglucose give a structural explanation why the carbohydrate-specific components of different families cannot complement each other.
AB - Background: The bacterial phosphoenolpyruvate-dependent phosphotransferase system (PTS) mediates the energy-driven uptake of carbohydrates and their concomitant phosphorylation, In addition, the PTS is intimately involved in the regulation of a variety of metabolic and transcriptional processes in the bacterium. The multiprotein PTS consists of a membrane channel and at least four cytoplasmic proteins or protein domains that sequentially transfer a phosphoryl group from phosphoenolpyruvate to the transported carbohydrate, Determination of the three-dimensional structure of the IIB enzymes within the multiprotein complex would provide insights into the mechanisms by which they promote efficient transport by the membrane channel IIC protein and phosphorylate the transported carbohydrate on the inside of the cell,Results: The crystal structure of the IIB enzyme specific for cellobiose, IIBcellobiose (molecular weight 11.4 kDa), has been determined to a resolution of 1.8 Angstrom and refined to an R factor of 18.7% (R(free) of 24.1%). The enzyme consists of a single four-stranded parallel beta sheet flanked by helices on both sides. The phosphorylation site (Cys10) is located at the C-terminal end of the first beta strand, No positively charged residues, which could assist in phosphoryl-transfer, can be found in or near the active site. The fold of IIBcellobiose is remarkably similar to that of the mammalian low molecular weight protein tyrosine phosphatases.Conclusions: A comparison between IIBcellobiose and the structurally similar low molecular weight protein tyrosine phosphatases provides insight into the mechanism of the phosphoryltransfer reactions in which IIBcellobiose is involved, The differences in tertiary structure and active-site composition between IIBcellobiose and the glucose-specific IIBglucose give a structural explanation why the carbohydrate-specific components of different families cannot complement each other.
KW - carbohydrate transport
KW - cysteine phosphorylation
KW - IIB enzymes
KW - PTS
KW - X-ray structure
KW - 3-DIMENSIONAL NMR-SPECTROSCOPY
KW - ESCHERICHIA-COLI
KW - PHOSPHOTRANSFERASE SYSTEM
KW - STAPHYLOCOCCUS-AUREUS
KW - NUCLEOTIDE-SEQUENCE
KW - CATALYTIC MECHANISM
KW - BACILLUS-SUBTILIS
KW - GLUCOSE PERMEASE
KW - IIA-DOMAIN
KW - ENZYME-II
JO - Structure
JF - Structure
van Montfort RLM, Pijning T, Kalk KH, Reizer J, Saier Jr. MH, Thunnissen MMGM et al. The structure of an energy-coupling protein from bacteria, IIBcellobiose, reveals similarity to eukaryotic protein tyrosine phosphatases. Structure. 1997 feb 15;5(2):217-225. https://doi.org/10.1016/S0969-2126(97)00180-9


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Twitter revamps sign-up flow in bid to boost numbers
1 Sep 2014103 Views
In its quest to increase its number of users, microblogging site Twitter has introduced a new streamlined sign-up flow that includes recommendations and subject preferences.
This is the first update to the sign-up process in three years and endeavours to make Twitter easier to understand and start using from the get-go.
One of the main problems for users starting out on Twitter has been who to follow and how to start interacting in a meaningful way with other users.
Rather than suggesting a few users to follow, the new sign-up flow allows people to pick subjects that interest them, such as music, sports, entertainment, news, technology, fashion, humour and popular accounts.
Users can also see sample tweets from suggested accounts before deciding who to follow.
Twitter has been battling the perception that user growth is stalling.
However, in June, the company reported it had 271m monthly active users, up 6.3pc.
Twitter bird image at top via Shutterstock
Twitter is a Silicon Republic Featured Employer, comprised of top tech companies that are hiring now
Related: social media, Twitter, internet


text:
Park opens for play
After years of planning by county officials, DeVaul Henderson Park finally opened up to the public on Saturday, March 7.
The park is not totally completed, but Saturday marked the unveiling of the soccer/football fields, a walking trail, a senior boys' baseball field and the concession stands.
"I think it's great that the county in investing in our kids," RHRA President Sanford Carter said. "This facility is definitely needed because we've outgrown the facilities that we have."
Carter said one of the goals of the rec association is to bring rec events, like the popular 'Battle of the Hill' football event, onto the new fields.
"Most people don't realize this has been 14 years in the making," County Commissioner Toby Roberts said.
Roberts said the park is designed not just for kids, but for people of all ages. He said the park's walking trail will eventually stretch all the way to J.F. Gregory Park and is accessible for golf carts, walking and bicycles.
Roberts said the park would have been built earlier, but it took many years of negotiating with land owners Rayonier to attain the land. He said Henderson, as county attorney, began working on the project in 1996 and was instrumental in keeping everyone on track and beginning the legal process on the land.
Just as they were about to give up on the property, Johnny Murphy, who has a long track record in negotiating with Rayonier, was brought in to help, and Murphy helped sealed the deal.
"Murphy helped negotiate the contract down to $6,000 an acre, which is a great deal by any stretch of the imagination," County Commission Chairman Jimmy Burnsed said. "So we owe a great deal of gratitude for Bryan Land and Timber for this as well as donating about $800,000 worth of clearing."
Burnsed said the park is a "state of the art complex. There's nowhere you'll see synthetic athletic fields like this outside of Atlanta." He said the park has thus far costed $7 million, but "all of this is being paid for with the one cent SPLOST money. It's not being added to your home taxes. Probably two-thirds of that tax money comes from money spent by people passing through South Bryan County."
"At the end of the day, the citizens of Bryan County are the winner in this deal," Roberts said. "The word is not completely out yet, but I think everyone will get excited about this project once they spend some time in the park."
A ribbon cutting was conducted, but, before that, Henderson's children and widow took part in a dedication ceremony. Henderson's eldest son Frank Henderson said he and his brothers spent many years playing RHRA sports and their dad spent many years as an RHRA coach.
"This park would be a dream fulfilled for him," Frank Henderson said. "I remember when we used to travel to places like Statesboro and he would always comment on how nice the facilities were there. He would always say, 'We need something like this in Richmond Hill,' and now we have that. I know our dad would be proud of this wonderful place and be truly honored to know that kids will now have an opportunity to play in a place that bears his name."
The remainder of day included a live concert by local musician Larry Barker, softball and soccer clinics, and the kick-off of Little League Baseball season.
South Bryan Recreation Director Kay Green said phase one of the park is almost complete. Weather conditions halted the completion of the grass soccer fields, but she said that and three additional softball fields will be completed by fall. She anticipates another celebration to be held in early fall when the remainder of phase one is complete.
Also coming soon is a connecting walkway to hook the park trail up to the existing walking trail on Hwy. 144. Green said the grants have already been applied for, so it is in the works.
Future phases will feature tennis courts, a new gymnasium with basketball courts, a disc golf course and a dog park. For more information on the park, call 756-4626 or visit www.RHRASports.org.


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Seabrook, TX (Bayport Blvd / Repsdorph Rd)
Bayport Blvd / Repsdorph Rd
About Seabrook, TX (Bayport Blvd / Repsdorph Rd)
Bayport Blvd / Repsdorph Rd median real estate price is $302,142, which is more expensive than 80.5% of the neighborhoods in Texas and 64.1% of the neighborhoods in the U.S.
The average rental price in Bayport Blvd / Repsdorph Rd is currently $1,283, based on NeighborhoodScout's exclusive analysis. Rents here are currently lower in price than 45.0% of Texas neighborhoods.
Bayport Blvd / Repsdorph Rd is an urban neighborhood (based on population density) located in Seabrook, Texas.
Bayport Blvd / Repsdorph Rd real estate is primarily made up of medium sized (three or four bedroom) to large (four, five or more bedroom) single-family homes and apartment complexes/high-rise apartments. Most of the residential real estate is occupied by a mixture of owners and renters. Many of the residences in the Bayport Blvd / Repsdorph Rd neighborhood are established but not old, having been built between 1970 and 1999. A number of residences were also built between 2000 and the present.
Real estate vacancies in Bayport Blvd / Repsdorph Rd are 6.7%, which is lower than one will find in 63.2% of American neighborhoods. Demand for real estate in Bayport Blvd / Repsdorph Rd is above average for the U.S., and may signal some demand for either price increases or new construction of residential product for this neighborhood.
Many things matter about a neighborhood, but the first thing most people notice is the way a neighborhood looks and its particular character. For example, one might notice whether the buildings all date from a certain time period or whether shop signs are in multiple languages. This particular neighborhood in Seabrook, the Bayport Blvd / Repsdorph Rd neighborhood, has some outstanding things about the way it looks and its way of life that are worth highlighting.
Bayport Blvd / Repsdorph Rd has the amazing distinction of housing more same sex couples living together than 98.9% of neighborhoods in the U.S. If you are seeking such a neighborhood, NeighborhoodScout's analysis shows that this is one place that you should consider.
In addition, the Bayport Blvd / Repsdorph Rd neighborhood stands out within Texas for its college student friendly environment. NeighborhoodScout's analysis reveals that this neighborhood is home to a number of college students, is relatively walkable, and above average in safety. In combination, this makes it stand out for a good place for college students to consider. Because a number of college students live here, this neighborhood may be close to a college campus and offer certain amenities nearby geared towards the student body. While it's not an environment for everyone, ambitious scholars can enjoy seasonal excitement between semesters and school breaks, and parents can rest easy knowing that the area has an above average safety rating. For each of these reasons, the neighborhood is rated among the top 6.7% of college-friendly places to live in TX. In addition to being an excellent choice for college students, this neighborhood is also a very good choice for highly educated executives.
Did you know that the Bayport Blvd / Repsdorph Rd neighborhood has more West Indian ancestry people living in it than nearly any neighborhood in America? It's true! In fact, 0.1% of this neighborhood's residents have West Indian ancestry.
The neighbors in the Bayport Blvd / Repsdorph Rd neighborhood in Seabrook are upper-middle income, making it an above average income neighborhood. NeighborhoodScout's exclusive analysis reveals that this neighborhood has a higher income than 84.6% of the neighborhoods in America. In addition, 1.0% of the children seventeen and under living in this neighborhood are living below the federal poverty line, which is a lower rate of childhood poverty than is found in 85.5% of America's neighborhoods.
In the Bayport Blvd / Repsdorph Rd neighborhood, 49.5% of the working population is employed in executive, management, and professional occupations. The second most important occupational group in this neighborhood is sales and service jobs, from major sales accounts, to working in fast food restaurants, with 24.3% of the residents employed. Other residents here are employed in manufacturing and laborer occupations (14.4%), and 11.8% in clerical, assistant, and tech support occupations.
The most common language spoken in the Bayport Blvd / Repsdorph Rd neighborhood is English, spoken by 87.2% of households. Some people also speak Spanish (9.2%).
Boston's Beacon Hill blue-blood streets, Brooklyn's Orthodox Jewish enclaves, Los Angeles' Persian neighborhoods. Each has its own culture derived primarily from the ancestries and culture of the residents who call these neighborhoods home. Likewise, each neighborhood in America has its own culture – some more unique than others – based on lifestyle, occupations, the types of households – and importantly – on the ethnicities and ancestries of the people who live in the neighborhood. Understanding where people came from, who their grandparents or great-grandparents were, can help you understand how a neighborhood is today.
In the Bayport Blvd / Repsdorph Rd neighborhood in Seabrook, TX, residents most commonly identify their ethnicity or ancestry as German (22.4%). There are also a number of people of Irish ancestry (17.4%), and residents who report Mexican roots (13.0%), and some of the residents are also of English ancestry (11.3%), along with some French ancestry residents (5.4%), among others.
How you get to work – car, bus, train or other means – and how much of your day it takes to do so is a large quality of life and financial issue. Especially with gasoline prices rising and expected to continue doing so, the length and means of one's commute can be a financial burden. Some neighborhoods are physically located so that many residents have to drive in their own car, others are set up so many walk to work, or can take a train, bus, or bike. The greatest number of commuters in Bayport Blvd / Repsdorph Rd neighborhood spend between 15 and 30 minutes commuting one-way to work (41.6% of working residents), which is shorter than the time spent commuting to work for most Americans.
Here most residents (84.6%) drive alone in a private automobile to get to work. In addition, quite a number also carpool with coworkers, friends, or neighbors to get to work (10.9%) . In a neighborhood like this, as in most of the nation, many residents find owning a car useful for getting to work.
AGE OF Seabrook, TX (Bayport Blvd / Repsdorph Rd) HOMES
TYPE OF Seabrook, TX (Bayport Blvd / Repsdorph Rd) HOMES
SIZE OF Seabrook, TX (Bayport Blvd / Repsdorph Rd) HOMES
Employment Industries in Bayport Blvd / Repsdorph Rd
in Bayport Blvd / Repsdorph Rd
in Seabrook
in Texas
Seabrook VIOLENT CRIMES
Seabrook Property CRIMES
CLEAR CREEK ISD
District Quality Compared to Texas
Better than of TX school districts.
Houston-The Woodlands-Sugar Land, TX Metro Area regional investment potential
Housing Affordability Trends: Houston-The Woodlands-Sugar Land, TX Metro Area
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Forgive Us Our Debts
June 10, 2015 April 11, 2018 Leave a Comment on Forgive Us Our Debts
I spent my first two years of college at a private liberal arts school in Michigan. I chose the school not because of its academic excellence or even necessarily its "vibrant Christian faith"—although faith was becoming increasingly important to me as decision time approached. No, I did not choose the school because of its rigor or research but because I really liked its downtown area.
The downtown was basically one road, Eighth Street, and it had heated sidewalks and beautiful old buildings. There were two coffee shops brimming with life on the same block. It had a store that sold greeting cards from Curly Girl Designs, which were my favorite thing ever as a teenager.
It was fate.
It might seem silly, but I'm being honest with you. And as an 18 year-old girl with extremely sound logic, I declared that God was calling me to this school and I could not be shaken. No matter that a year's tuition was half the price of my parents' house, I was going to be an elementary school teacher! I'd be able to pay those loans off in no time.
Why my parents let me go there I'll never understand. Maybe it was all the tears and begging. How can you say no when your child tells you, "I know it's God's plan for me?" It was against all rationale that I enrolled at Hope College. I'm still figuring out why that sweet, naïve 18 year-old was so obediently bold in the pursuit of a college based primarily on the type of greeting card sold at a store downtown.
So there I was, sitting in a small, windowless room in the financial aid office between both of my parents. A short woman sat across from us, pushing paper after paper our way until we had signed this and initialed that. She said words like "interest rate" and "unsubsidized" and "cosign" and I just smiled and nodded, not realizing at the time how easy it was to find your self (and, in my case, my parents) in tens of thousands of dollars in debt.
I wasn't thinking about the money during my freshman year. I had a good amount of savings from my summer job as a hostess, which I didn't hesitate to spend on lattes and clothes from the Gap Outlet. My days were spent doing classic freshman things: spending hours singing "Eye of the Tiger" with 150 other girls and perfecting hand motions so that we could perform in a beloved traditional competition between freshman and sophomores, going to house parties in which the hosts make you pancakes and sing worship songs, and taking trips to the local donut shop, Good Time Donuts, where you were never 100 percent sure whether the owner would be entirely clothed.
Oh, you didn't do that as a freshman?
I was much too wrapped up in a whirlwind of crazy traditions and changing friend groups to remember—or even care—that I was $35,000 in the hole.
Sophomore year was a little different. My dear grandmother died early in the fall which was a devastating loss for our family. Only two weeks after, we got the news that my dad was diagnosed with Parkinson's disease. What started as a small twitch in his shoulder quickly spiraled into his drastic loss of balance, coordination and energy.
I remember talking to him on the phone one evening. I was sitting on an old, mustard brown corduroy couch, keeping watch on the residents entering to and from the dorm. I was a RA, so this was a weekly tradition of mine. After a minute of talking to him, I laughed and asked, "Dad, are you drunk?" He had been slurring his words and talking slowly. He wasn't a heavy drinker, so it seemed uncharacteristic of him, but who knows what parents do when you leave for school?
He said no, he was not drunk. When I had my mom back on the line, she told me that it was slowly becoming harder for him to speak. Just a couple of months after that, we accepted it as his new way of life. The pills weren't helping and the doctors didn't know why it was progressing so fast.
Meanwhile, at Hope College, we were entering the season of housing decisions. For sophomores at Hope College, this is a cruel time where friends become enemies and loyalties are out the window. Junior year is the transition from on-campus dorms to on-campus cottages and apartments, meaning everyone has to decide who they do—and don't—want to live with next year. Tears are shed. Backs are stabbed.
I wanted no part of it. As hard as I tried, I couldn't shake the feeling that I wasn't supposed to be there next year. I still loved the town, but I couldn't take one more year at that school.
So? Said God. Don't.
So, after much prayer and debate and anxiety and more prayer, I signed up for a tour at the university 20 miles away and decided to commute there while still living in town. I finished up my sophomore year at Hope and then said goodbye without much sadness and with zero regret. In fact, I felt more confident about leaving Hope than I had felt about going there initially. And it's not easy to surpass that level of confidence. I'm generally a very indecisive person.
I think the decision to leave was influenced by a myriad of events. I didn't want to put my parents into more debt, especially now that medical bills were becoming part of the picture. My boyfriend, Brenin, and I were talking seriously about marriage and I couldn't let him marry a woman $80,000 in debt (and at that point I had given up on wanting to teach so I wouldn't be bringing in the big bucks anymore…). There were plenty of other small reasons, too, including being fed up with the culture and politics of the school.
So I left, went to another school, then went to another school, then got married, and now I'm living in Minnesota and will finish up school in December.
For a while there, I was really questioning God's purpose for my enrollment at Hope. Had I been that off? Did He really not want me to go to Hope and I just screwed myself into a huge pile of debt? Why had I felt so strongly that it was where I was supposed to go?
I wrestled with this question for almost two years. I knew that being tied down with debt was not God's best for His children, but He seemed to lead me right into the trap.
But He knew what He was doing. Even in my doubt and anger, He stayed patient and faithful. See, my dad had to apply for full-time disability this year. He's no longer in a physical condition to do his job as a civil engineer. But, when someone goes on disability, they're somehow potentially eligible for loan forgiveness. And after jumping through hoops and making phone calls and faxing papers, after cosigning their lives away that fateful day four years ago, my parents told me that those loans—$55,000—have been forgiven.
Wiped clean.
It's as if, financially, I never went to Hope College.
I fell to the ground and cried. A mountain so impossible to climb and it was simply pushed out of the way to make a clear path.
I was speechless in awe of my God.
At Hope, we had chapel every Monday, Wednesday and Friday. Each morning, our worship leader, a young guy with great facial hair and horn-rimmed glasses, would remind us of the gracious words of Psalm 103. "As far as the east," he'd say, stretching out his left arm, "is from the west," he continued, right arm outstretched, "so far has he removed our transgressions from us."
That reminder was like sweet honey each time. I would believe anew each morning that God really did find pleasure in purifying His children, relieving us of our burdens and forgiving us our trespasses.
But those words I heard every other day at Hope…those words I recited as a toddler in Catholic school: "forgive us our debts as we forgive our debtors"…Never did I think God would work so tangibly as to take a serious material burden and lift it as if it had been light as a feather, throwing it as far from me as the east is from the west.
Because what would've taken me my entire life to pay off—a life of strict budgeting and sacrifice—took God but a moment. What would've been back-breaking work for me was a characteristic act of grace, love, and kindness from the Father who says, "For it is by grace you have been saved, through faith—and this is not from yourselves, it is the gift of God—not by works, so that no one can boast."
Thanks be to God for His abundant, unconditional, fierce love for His children.
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I'm so glad you're here! My name is Bailey, and these are my Invitations to Abundant Living. Grab a cup of coffee and make yourself at home!
I want to be rich in memories not money / Our love is our inheritance, honey Florida 2020
To sum up our Hogwarts experience in 3 words: Magical. Butterbeer. Terigettingreallyexcited.
Merry Christmas from the Richardson's! ...I'd like to say this is 2 days late because we were so busy living in the moment and soaking in all the wonder and family time...really it's just because I napped all day yesterday #holidayhangover 😆
For us who long to experience Hope & Joy this season but seem to be surrounded by grief & suffering instead— Maybe it's not either/or. Maybe it's impossible to experience true Joy without deep suffering. Maybe Hope comes alive when we've persevered through the muck of grief and despair. Perhaps joy to the world is less about sparkly holiday parties and shiny gifts and peaceful nights around the soft glow of the tree, but Joy is a weary world met by a humble baby who showed us how to keep going in spite of brokenness because there is glory to come. Perhaps Hope & Joy are born in the lowliest, dirtiest of places— reminding us we don't have to clean up in order to get them. But then how do we get Hope & Joy? Maybe we lean in and embrace the reality of our brokenness— walking right through (not dodging around!) the door of suffering, armed with the hope that we'll meet His glory and grace? "Therefore, since we have been justified through faith, we have peace with God through our Lord Jesus Christ, through whom we have gained access by faith into this grace in which we now stand. And we boast in the hope of the glory of God. Not only so, but we also glory in our sufferings, because we know that suffering produces perseverance; perseverance, character; and character, hope. And hope does not put us to shame, because God's love has been poured out into our hearts through the Holy Spirit, who has been given to us." Romans 5:1-5 Hope is ultimately produced by suffering. It's okay to be suffering this holiday season. In fact, suffering may be the one absolutely necessary thing for Hope to come alive. Hope arrived by way of an unlikely woman in a low place; Hope surrounded Himself with the broken and beat up; and Hope was eventually hung on a cross. Hope endures and embraces suffering because Hope believes in the glory to come.


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E-SPORT ATHLETE ALLERT VAN DER WAL WINS THE FIRST FORMULA V CHALLENGE
Winning time even a second faster than Buemi!
On Sunday, at the Auto Zürich, the four best of the four-day qualification determined the first winner of the Formula V Challenge. Allert van der Wal, Fabian Heggli, Roy Ricklin and Phillip Schellenberg competed against each other at 3:00 pm. The semi-finals contested the pilots in an 8-minute race. Allert van der Wal was able to prevail in the first semi-final against Phillip Schellenberg and thus secured his place in the final. In the second semi-final, Roy Ricklin won against Fabian Heggli. The two finalists contested two 4-minute races, after the first four minutes, they exchanged places. The best lap time won, and so Allert van der Wal won the challenge. With his winning time of 1: 11.228 minutes, the Dutchman was even able to completed the Formula E track of New York faster than Formula E star Sébastien Buémi!
Allert van der Wal can look forward to an exciting weekend in Maranello, this was the prize for the winner. The second and third place winners did not go empty-handed: they won a voucher for the first Formula V Racing Lounge, which will be opened in Cham in April 2019. We thank you again for your huge interest in our simulators in Zurich and look forward to seeing you soon in Cham.


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43 days in Europe Itinerary
Created using Inspirock Europe Trip Planner
Start: Brisbane, Australia
Naples, Italy
Syracuse, Italy
Marne-la-Vallee, France
Versailles, France
Fly to Mulhouse, Bus to Basel SBB, Train to Zurich
Fly to Milan Malpensa, Train to Verona
End: Brisbane, Australia
Fri, Sep 15 - Fri, Oct 27 Edit
Eternal City
Aptly nicknamed the Eternal City, Rome is the birthplace of the Roman Empire, one of the world's greatest civilizations ever.
You'll discover tucked-away gems like Church of St. Louis of the French and Chiesa di Sant'Ignazio di Loyola. Relax by the water at Acqua e Sale - Stabilimento Balneare and Stabilimento Balneare Amerigo. The adventure continues: take in the architecture and atmosphere at St. Peter's Basilica, admire the local landmark of Trevi Fountain, explore the galleries of Vatican Museums, and take a stroll through Via Condotti.
To find other places to visit, ratings, where to stay, and other tourist information, read Rome trip planner.
Brisbane, Australia to Rome is an approximately 26-hour flight. The time zone difference when traveling from Brisbane to Rome is minus 9 hours. When traveling from Brisbane in September, plan for a bit warmer days and about the same nights in Rome: temperatures range from 32°C by day to 18°C at night. Finish your sightseeing early on the 20th (Wed) to allow enough time to take a train to Naples.
Historic Sites · Beaches · Parks · Outdoors
Vatican City, Acqua e Sale - Stabilimento Balneare, Stabilimento Balneare Amerigo
See Italy Travel Guide
Naples is the capital of the Italian region Campania and the third-largest municipality in Italy after Rome and Milan. Start off your visit on the 20th (Wed): get to know the fascinating history of Lungomare Caracciolo, then wander the streets of Chiaia, and then get a taste of the local shopping with Via Toledo.
To find other places to visit, more things to do, where to stay, and other tourist information, read Naples route planning website.
Getting from Rome to Naples by train takes about 2 hours. Other options: drive; or fly. September in Naples sees daily highs of 31°C and lows of 20°C at night. Wrap up your sightseeing on the 20th (Wed) early enough to travel to Palermo.
Things to do in Naples
Shopping · Historic Sites · Neighborhoods
Chiaia
Scenic Walking Area
Lungomare Caracciolo
The capital of Sicily, Palermo was founded by the Phoenicians under the name of Ziz.
On the 21st (Thu), take in the architecture and atmosphere at Church of San Cataldo, stop by La Bottega nella Roccia, step into the grandiose world of Castello di Caccamo, then pause for some serene contemplation at Duomo di Monreale, and finally stroll the grounds of Catacombe dei Cappuccini. On the 22nd (Fri), you'll have a packed day of sightseeing: take in the architecture and atmosphere at Cattedrale di Palermo, admire the striking features of Norman Palace, pause for some serene contemplation at Chiesa del Gesu, then admire the masterpieces at Museum of tiles Stanze al Genio, and finally contemplate the long history of Palazzo Steri - Chiaramonte - Carcere dei penitenziati.
To find where to stay, traveler tips, reviews, and other tourist information, you can read our Palermo trip itinerary builder tool.
Traveling by flight from Naples to Palermo takes 4 hours. Alternatively, you can take a bus; or take a train. Cap off your sightseeing on the 23rd (Sat) early enough to go by car to Syracuse.
Things to do in Palermo
Historic Sites · Shopping · Museums
Caccamo, Duomo di Monreale
Duomo di Monreale
Norman Palace
Pearl of the Mediterranean
Philosopher Cicero once described Syracuse as "the greatest Greek city and the most beautiful of them all." A powerful city-state of ancient Greece, Syracuse now is the capital of the eponymous Italian province on the eastern coast of Sicily.
Kick off your visit on the 23rd (Sat): look for gifts at Mercato Di Siracusa, then head off the coast to Ortigia, then explore the ancient world of Temple of Apollo (Tempio di Apollo), and finally take in the architecture and atmosphere at Duomo di Siracusa. On the 24th (Sun), you'll have a packed day of sightseeing: pause for some serene contemplation at St. Nicholas Cathedral, take in the architecture and atmosphere at Chiesa Santa Chiara, and then explore the world behind art at Monastero del San salvatore.
For traveler tips, reviews, other places to visit, and more tourist information, read Syracuse trip itinerary tool.
Getting from Palermo to Syracuse by car takes about 3 hours. Other options: take a bus; or take a train. Wrap up your sightseeing by early afternoon on the 24th (Sun) to allow enough time to travel to Florence.
Things to do in Syracuse
Duomo di Siracusa
St. Nicholas Cathedral
Chiesa Santa Chiara
Birthplace of the Italian Renaissance
Considered a cultural, artistic, and architectural jewel of Italy, Florence is the birthplace of the Italian Renaissance.
Kick off your visit on the 25th (Mon): snap pictures at Ponte Vecchio, then relax in the rural setting at Castello di Verrazzano, and then get into the urban bustle at Comune Di Certaldo. On your second day here, admire the masterpieces at Gallerie Degli Uffizi, then stroll through Easy Living - Spiaggia sull'Arno, and then explore the world behind art at Florence Academy of Fine Arts.
To see reviews, photos, maps, and other tourist information, go to the Florence trip planner.
You can fly from Syracuse to Florence in 5.5 hours. Other options are to do a combination of car and ferry; or do a combination of train and ferry. In September, daily temperatures in Florence can reach 30°C, while at night they dip to 17°C. Cap off your sightseeing on the 27th (Wed) early enough to go by car to Nice.
Things to do in Florence
Museums · Beaches · Parks · Historic Sites
Comune Di Certaldo, Castello di Verrazzano
Gallerie Degli Uffizi
Gallerie Degli Uffizi tickets
Skip the Line: Uffizi Gallery Ticket Including Special Exhibits
Skip the Line: Uffizi Gallery Visit with Audio-Guided Tour
Skip the Line: Florence Uffizi Gallery Tickets
Florence Academy of Fine Arts
Florence Academy of Fine Arts tickets
Skip the Line: Florence Accademia Gallery and Michelangelo's David Ticket
Skip the Line: Accademia Gallery Visit with Audio-Guided Tour
Skip the Line: Florence Accademia Gallery Tickets
Nissa la Bella (Nice the Beautiful)
Well-known for the beautiful views of its famous Promenade des Anglais waterfront, Nice is an ethnically-diverse coastal port city on the French Riviera and the fifth most populated city in France.
Start off your visit on the 27th (Wed): get up close and personal with brilliant marine life at Marineland. Get ready for a full day of sightseeing on the next day: enjoy the sand and surf at Paloma Beach, then steep yourself in history at Villa Kerylos, and then steep yourself in history at Villa & Jardins Ephrussi de Rothschild.
For more things to do, other places to visit, and tourist information, read Nice attractions planner.
Traveling by car from Florence to Nice takes 4.5 hours. Alternatively, you can fly; or take a bus. Traveling from Florence in September, you can expect nighttime temperatures to be somewhat warmer in Nice, with lows of 21°C. Finish up your sightseeing early on the 28th (Thu) so you can travel to Marne-la-Vallee.
Parks · Zoos & Aquariums · Historic Sites · Beaches
St-Jean-Cap-Ferrat, Villa Kerylos, Marineland
Villa & Jardins Ephrussi de Rothschild
Paloma Beach
As a "new town" best known for its Euro Disney Park and resorts, Marne-la-Vallée is a modern family resort town.
Kick off your visit on the 29th (Fri): stop by Disney Store, admire the masterpieces at Barbizon School Museum (Musee de l'Ecole de Barbizon), and then tee off at Fontainebleau Golf Club. Keep things going the next day: look for gifts at Disney Village, then look for gifts at World of Disney, and then tee off at Golf Disneyland.
To see where to stay, traveler tips, more things to do, and other tourist information, read our Marne-la-Vallee trip planner.
Getting from Nice to Marne-la-Vallee by flight takes about 4.5 hours. Other options: take a train; or drive. Plan for slightly colder temperatures traveling from Nice in September, with highs in Marne-la-Vallee at 24°C and lows at 13°C. Finish up your sightseeing early on the 30th (Sat) so you can go by car to Paris.
Things to do in Marne-la-Vallee
Golf · Outdoors · Shopping · Museums
Fontainebleau Golf Club, Barbizon School Museum (Musee de l'Ecole de Barbizon)
Fontainebleau Golf Club
Barbizon School Museum (Musee de l'Ecole de Barbizon)
A beautiful and romantic city fit for any itinerary, Paris brims with historic associations and remains vastly influential in the realms of culture, art, fashion, food and design.
Shop till you drop at Le Marais and Champs-Elysees. Family-friendly places like Louvre Museum and Seine River will thrill your kids. When in Paris, make a side trip to see Chateau de Fontainebleau in Fontainebleau, approximately Fontainebleau away. There's still lots to do: explore the world behind art at Musee d'Orsay, pause for some photo ops at Arc de Triomphe, visit Montmartre, and take a stroll through Île de la Cité.
To find photos, more things to do, and tourist information, use the Paris online journey planner.
Paris is just a short distance from Marne-la-Vallee. In September, plan for daily highs up to 24°C, and evening lows to 13°C. Wrap up your sightseeing on the 5th (Thu) to allow time to drive to Versailles.
Museums · Historic Sites · Neighborhoods · Parks
Chateau de Fontainebleau
Musee d'Orsay
Royal Paradise
Renowned for its vast royal palace and gardens built by King Louis XIV, Versailles is also one of the wealthiest suburbs of Paris and home to a new cultural notability, such as a thriving artistic and musical scene.
Kick off your visit on the 6th (Fri): admire the striking features of The Trianons & The Hamlet, then get a sense of history and politics at Hotel de Ville, and then tee off at Golf National. On the 7th (Sat), you'll have a packed day of sightseeing: learn about wildlife with up-close encounters at Parc Zoologique et Chateau de Thoiry and then tee off at Golf des Yvelines.
To see where to stay, reviews, and other tourist information, refer to the Versailles trip maker site.
Getting from Paris to Versailles by car takes about an hour. Other options: take a train; or take a bus. October in Versailles sees daily highs of 19°C and lows of 9°C at night. Finish your sightseeing early on the 7th (Sat) so you can travel to Zurich.
Things to do in Versailles
Golf · Outdoors · Parks · Zoos & Aquariums
Golf des Yvelines, Golf National, Parc Zoologique et Chateau de Thoiry
Golf des Yvelines
The Trianons & The Hamlet
Golf National
Big Small Town
The financial hub of Switzerland, Zurich is most often associated with money and banks.
Start off your visit on the 8th (Sun): make a trip to Niederdorf, get curious at Swiss Science Center Technorama, and then get engrossed in the history at Landesmuseum. On the next day, wander the streets of Bahnhofstrasse, pause for some photo ops at Lion Monument, then tour the pleasant surroundings at Glacier Garden (Gletschergarten), and finally explore the world behind art at The Rosengart Collection.
To see traveler tips, where to stay, and other tourist information, read our Zurich day trip planning website.
Traveling by combination of flight, bus, and train from Versailles to Zurich takes 5.5 hours. Alternatively, you can fly; or drive. In October, daytime highs in Zurich are 17°C, while nighttime lows are 8°C. Wrap up your sightseeing on the 10th (Tue) early enough to travel to Verona.
Things to do in Zurich
Museums · Neighborhoods · Parks · Shopping
Lucerne, Swiss Science Center Technorama
The Rosengart Collection
Glacier Garden (Gletschergarten)
Swiss Science Center Technorama
See Switzerland Travel Guide
City of Romeo and Juliet
The famous setting for Shakespeare's star-crossed lovers, Romeo and Juliet, Verona is one of northern Italy's main tourist destinations, largely owing to its incredibly rich artistic heritage.
On the 10th (Tue), get in on the family fun at Gardaland Park. On your second day here, explore the historical opulence of Museo di Castelvecchio, contemplate in the serene atmosphere at Basilica di San Zeno Maggiore, get a taste of the local shopping with Piazza delle Erbe, see the grandeur of opera at Arena di Verona, then examine the collection at Casa di Giulietta, and finally take in the architecture and atmosphere at San Fermo Maggiore, Verona.
To see other places to visit, ratings, maps, and more tourist information, refer to the Verona trip itinerary app.
You can do a combination of flight and train from Zurich to Verona in 5 hours. Other options are to drive; or fly. While traveling from Zurich, expect somewhat warmer days and about the same nights in Verona, ranging from highs of 22°C to lows of 11°C. Wrap up your sightseeing on the 11th (Wed) early enough to travel to Berlin.
Things to do in Verona
Theme Parks · Historic Sites · Neighborhoods · Nightlife
Gardaland Park
Basilica di San Zeno Maggiore
Piazza delle Erbe
Athens of the Spree
The country's capital and largest city, Berlin is a diverse urban center boasting a lively nightlife and countless things to do.
On the 12th (Thu), take a stroll through Potsdamer Platz, stroll around Kurfurstendamm, then browse the range of quality goods at Kaufhaus des Westens (KaDeWe), then look for gifts at Rausch Schokoladenhaus, and finally learn something new at Ritter Sport Bunte Schokowelt.
To see reviews, ratings, where to stay, and tourist information, use the Berlin online trip itinerary builder.
Traveling by flight from Verona to Berlin takes 6 hours. Alternatively, you can drive; or take a train. Finish your sightseeing early on the 12th (Thu) to allow enough time to travel to Munich.
Shopping · Neighborhoods · Parks · Classes
Kaufhaus des Westens (KaDeWe)
Kurfurstendamm
See Germany Travel Guide
Village of a Million People
Often described as the city of laptops and lederhosen, Munich is an international center of business, engineering, research, and medicine that still maintains a rich cultural heritage and age-old traditions.
BMW Museum and Deutsches Museum are good opportunities to explore the local culture. Explore hidden gems such as Munich Residenz and Lake Tegernsee. Go for a jaunt from Munich to Augsburg to see Fuggerei about 1h 5 min away. Next up on the itinerary: explore the world behind art at Alte Pinakothek, hunt for treasures at Viktualienmarkt, and make a trip to Olympic Tower.
For maps, photos, and tourist information, use the Munich online day trip planner.
Traveling by flight from Berlin to Munich takes 3.5 hours. Alternatively, you can take a train; or drive. In October, plan for daily highs up to 16°C, and evening lows to 5°C. Finish up your sightseeing early on the 15th (Sun) so you can go by car to Salzburg.
Museums · Childrens Museums · Shopping · Parks
Lake Tegernsee, Fuggerei
Munich Residenz
Alte Pinakothek
Rome of the North
Surrounded by mountain ranges and boasting a well-preserved city center, Salzburg melds culture and history.
Start off your visit on the 16th (Mon): take in nature's colorful creations at Mirabell Palace, browse the different shops at EUROPARK, stroll the grounds of Petersfriedhof, then contemplate in the serene atmosphere at St. Peter's Abbey (Stift St. Peter), and finally stop by Steingasse. Keep things going the next day: steep yourself in history at Mozart Residence (Mozart Wohnhaus), take an in-depth tour of Mozarts Geburtshaus, steep yourself in history at Kapitelplatz & Kapitelschwemme, then take your sightseeing to a higher altitude at Untersberg, and finally explore the historical opulence of Schloss Hellbrunn.
To find reviews, where to stay, traveler tips, and more tourist information, read Salzburg attractions planner.
Traveling by car from Munich to Salzburg takes 1.5 hours. Alternatively, you can take a train; or take a bus. In October, daily temperatures in Salzburg can reach 17°C, while at night they dip to 7°C. Finish your sightseeing early on the 17th (Tue) so you can drive to Vienna.
Things to do in Salzburg
Historic Sites · Museums · Neighborhoods · Parks
Steingasse
Schloss Hellbrunn
Untersberg
See Austria Travel Guide
The cultural, economic, and political center of the country, Vienna has developed from its early Celtic and Roman roots into a medieval and Baroque city, with an old town that was designated a World Heritage Site in 2001.
Deepen your sense of the past at sights like Schonbrunn Palace and St. Stephen's Cathedral. Explore hidden gems such as The Hofburg and Wachau Valley. There's lots more to do: contemplate the long history of Ringstrasse, take a stroll through Mariahilfer Strasse, make a trip to Graben and Kohlmarkt, and admire the landmark architecture of Hundertwasserhaus.
To find maps, ratings, reviews, and other tourist information, refer to the Vienna travel route planner.
You can drive from Salzburg to Vienna in 3 hours. Other options are to take a train; or fly. In October, plan for daily highs up to 17°C, and evening lows to 8°C. Wrap up your sightseeing on the 22nd (Sun) to allow time to travel to Venice.
Parks · Historic Sites · Theme Parks · Neighborhoods
Wachau Valley
Schonbrunn Palace
The Hofburg
City of Romance
Virtually unchanged for the last six centuries, Venice is actually a group of islands made famous by a series of canals, bridges, monuments, piazzas, and narrow pedestrian lanes.
Step off the beaten path and head to Peggy Guggenheim Collection and Cannaregio. Attractions like Canal Grande and Piazza San Marco make great kid-friendly stops. And it doesn't end there: don't miss a visit to Basilica di San Marco, take in panoramic vistas at St Mark's Campanile, snap pictures at Ponte di Rialto, and pause for some serene contemplation at Basilica di Santa Maria della Salute.
To see traveler tips, where to stay, photos, and tourist information, read our Venice day trip planning app.
You can fly from Vienna to Venice in 4.5 hours. Other options are to drive; or take a train. Traveling from Vienna in October, expect Venice to be a bit warmer, temps between 22°C and 12°C. Wrap up your sightseeing on the 25th (Wed) to allow time to travel back home.
Things to do in Venice
Doge's Palace
Peggy Guggenheim Collection
60 days in Switzerland BY A USER FROM MALAYSIA Zurich · Meiringen · Bern 60 days in Europe BY A USER FROM AUSTRALIA Rome · Florence · Venice 60 days in Africa, Europe & United States BY A USER FROM AUSTRALIA Johannesburg · Cape Town · Cairo 22 days in Europe BY A USER FROM INDIA Vienna · Salzburg · Neustift im Stubaital 15 days in Austria, Switzerland & Italy BY A USER FROM INDIA Vienna · Zurich · Venice 19 days in Italy, Germany & Paris BY A USER FROM COSTA RICA Rome · Florence · Venice 42 days in Italy, France & United Kingdom BY A USER FROM AUSTRALIA Rome · Florence · Venice 3 days in Paris BY A USER FROM UNITED STATES Cathédrale Notre-Dame de Paris · Musee d'Orsay · Louvre Museum 5 days in Switzerland BY A USER FROM UNITED KINGDOM Geneva · Interlaken · Zurich 17 days in Italy BY A USER FROM CANADA Florence · Assisi · Palermo 14 days in Italy BY A USER FROM MALAYSIA Rome · Assisi · Florence 2 days in Venice BY A USER FROM ITALY Campo del Ghetto · Centro Storico · Natural History Museum
Venice trip planner
Austria trip planner
Province of Venice trip planner
Landmarks · Ruins · Sacred & Religious Sites
Italy is a land of high fashion, fine art, exquisite architecture, luxury sports cars, outstanding cuisine--and an insatiable taste for "la dolce vita." It's also home to the greatest number of World Heritage Sites in the world, making it an ideal place for your next holiday. The country boasts a varied landscape of mountain ranges, alpine lakes, and coastal towns, so it's no wonder travelers often refer to it as the bel paese (beautiful country). With so many places to visit, visitors often have a difficult time planning their itinerary. The smaller villages each feature a distinct character and a blend of architecture, art, and cuisine. In the country, you'll find countless archeological sites dating back to Roman times and beyond. The country's cities and seaside resorts are cosmopolitan powerhouses with museums, galleries, restaurants, shops, open-air markets, and pedestrian-friendly historic areas.
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Bodies of Water · Mountains · Landmarks
Immerse yourself in a snow-capped mountain wonderland in Switzerland's serene Alpine setting. See the world-renowned Matterhorn, Switzerland's second-highest mountain at 4,478 m (14,962 ft) tall, or zoom down the mountains on toboggan, ski, or snowboard. In the warmer seasons hike around the rolling green hillsides covered with pine trees and picturesque aqua blue lakes. Luxurious cities dotted with cozy wooden chalets and colorful flowerbeds balance quaintness with first-class cultural offerings. Indulge in the country's opulence of milk chocolate, cheese fondue, and keg-carrying St. Bernard dogs.
Specialty Museums · Landmarks · Historic Sites
Germany is the home of high culture, fine art, classical music, world-class sports, award-winning cuisine--and some of the world's best beers. It's also one of the major economic and political powers of the European continent. One of the founding members of the European Union, Germany is a federation of 16 states. Each boasts its own distinct culture, art, cuisine, regional traditions, and array of things to do. The country is known worldwide for its precision engineering and high-tech products. Equally, though, Germany is admired for its old-world charm and what is locally known as gemutlichkeit (coziness). This is one of the easiest countries in the world to explore, offering an abundance of sightseeing opportunities. German transportation runs with German efficiency. Therefore, getting around the various regions is almost always easy, quick, and pleasant. Visit the cities to explore museums, art galleries, modern restaurants, and trendy shops. Also be sure to venture deeper into the countryside. Here, you can discover ancient castles and bustling little villages. Often in these off-the-beaten-path areas, the main tourist attraction remains the simple hospitality of the friendly locals.
Castles · Art Museums · Specialty Museums
Situated in the Central European Alps, Austria combines an alluring bundle of elegant urban architecture, cultural centers, and dramatic landscapes. This German-speaking country of 8.5 million residents is known for its rich history, dating back to the Hapsburg Empire, as well as its art, music, and scenery. Along with the neighboring country of Switzerland, Austria serves as the winter sports capital of Europe and is home to some of the continent's most popular ski resorts. This landlocked nation draws visitors from across the globe to its mountains, historical villages, and culturally rich cities. Experience trekking in the Alps one day and drinking regional wine at a crowded pub after a day of sightseeing in the capital Vienna the next.


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