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Home / Meetings & Education / Annual Meetings and Scientific Sessions / 2019 Annual Meeting and Scientific Sessions / Scientific Program / Schedule at a Glance / Schedule by Day / Wednesday, April 3, 2019
← BACK TO SCHEDULE BY DAY
*Schedule by Day - Wednesday, April 3, 2019
Speaker Ready Open
Exhibitor Registration Open (Registration South)
Registration Open (Grand Caribbean Foyer & Pre-Function North)
OPENING PLENARY SESSION (Grand Caribbean 1-7)
Visit the ISHLT2019 Online Program Viewer to see the full abstracts from this session
Primary Audience: ALL
Chairs: Jeffrey J. Teuteberg, MD and Lara Danziger-Isakov, MD, MPH
8:00 AM Welcome/Program Chair Report
Lara Danziger-Isakov, MD, MPH, Children's Hospital Medical Center, Cincinnati, OH, USA
8:10 AM Thoracic Registry Report
Josef Stehlik, MD, MPH, University of Utah School of Medicine, Salt Lake City, UT, USA
8:20 AM IMACS Registry Report
Daniel J. Goldstein, MD, Montefiore Medical Center, Bronx, NY, USA
8:30 AM Journal Editor's Report
Mandeep R. Mehra, MD, FRCP, FACC, FESC. Brigham and Women's Hospital, Boston, MA, USA
8:40 AM President's Report
Jeffrey J. Teuteberg, MD, Stanford University School of Medicine, Stanford, CA, USA
8:55 AM (1) Clinical Outcomes by Intended Goal of Therapy in the MOMENTUM 3 Clinical Trial: Final Analysis of the 1028 Patient Full Cohort
D. Goldstein1, M. R. Mehra2, MOMENTUM 3 Investigators2. 1Dept of Cardiothoracic Surgery, Montefiore Medical Center, Albert Einstein College of Medicine, Bronx, NY, 2Brigham and Women's Hospital, Boston, MA
9:10 AM Expert Interactive Discussant for Clinical Outcomes by Intended Goal of Therapy in the MOMENTUM 3 Clinical Trial: Final Analysis of the 1028 Patient Full Cohort
Robert Kormos, MD, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
9:15 AM (2) INSPIRE: A Phase 3 Open-Label, Multicenter Study to Evaluate the Safety and Tolerability of LIQ861 in Pulmonary Arterial Hypertension (PAH) (Investigation of the Safety and Pharmacology of Dry Powder Inhalation of Treprostinil NCT03399604)
N. S. Hill1, J. P. Feldman2, S. Sahay3, D. J. Levine4, R. F. Roscigno5, T. A. Vaughn5, T. M. Bull6. 1Tufts Medical Center, Boston, MA, 2Arizona Pulmonary Specialists, Ltd, Phoenix, AZ, 3Weill Cornell Medicine, Institute of Academic Medicine, Houston Methodist Lung Center, Houston Methodist, Houston, TX, 4University of Texas Health Sciences Center at San Antonio, San Antonio, TX, 5Liquidia Technologies, Morrisville, NC, 6Anschutz Medical Campus, University of Colorado Denver, Aurora, CO
8:55 AM Expert Interactive Discussant for INSPIRE: A Phase 3 Open-Label, Multicenter Study to Evaluate the Safety and Tolerability of LIQ861 in Pulmonary Arterial Hypertension (PAH) (Investigation of the Safety and Pharmacology of Dry Powder Inhalation of Treprostinil NCT03399604)
Jean-Luc Vachiery, MD, Erasme University Hospital, Brussels, Belgium
9:35 PM Lifetime Achievement Award Recipient Lecture
John Wallwork, FRCS, Papworth Hospital, Cambridge, UK
Poster Mount Session 1 (Timor, Banda, Gardenia, Hibiscus)
Press Office Open (Philippine Sea)
Exhibit Hall Open (Oceana 6-12)
Coffee Break (Oceana 6-12)
Industry Theater Open (Oceana 2)
Poster Hall Open (Timor, Banda, Gardenia, Hibiscus)
SESSION 01 (ORAL): The Next Frontier in Thoracic Transplantation: Diagnostics and Therapies (Pacifica 1-2)
Primary Audience: BSTR
Secondary Audience: LTX, PEDS, PATH
Chairs: Marilia Cascalho, MD, PhD and Matthew G. Hartwig, MD
10:30 AM (5) Early Detection of Post-Transplant Lymphoproliferative Disorder Using Circulating Tumor DNA
J. Soo, J. Schroers-Martin, A. Garofalo, D. Kurtz, N. D'Emilio, H. Luikart, A. Alizadeh, K. Khush. Stanford University, Stanford, CA
10:45 AM (6) Distinct Heart Failure Phenotypes Identified by Myocardial Transcriptome Sequencing: Targets for Reverse Remodeling
P. Shah1, W. Zhu2, S. Navankasattusas3, D. K. Ramadurai3, S. S. Desai1, I. Taleb3, I. Efimov4, R. Singh5, N. Aliyev3, R. K. Iyer2, O. Wever-Pinzon6, S. McKellar7, W. T. Caine8, C. R. deFilippi9, J. Zhu10, S. Drakos6. 1Heart Failure and Transplantation, Inova Heart and Vascular Institute, Falls Church, VA, 2Inova Translational Medicine Institute, Falls Church, VA, 3University of Utah, Salt Lake City, UT, 4George Washington University, Washington, DC, 5Cardiac Surgery, Inova Heart and Vascular Institute, Falls Church, VA, 6Heart Failure and Transplantation, University of Utah, Salt Lake City, UT, 7Cardiac Surgery, University of Utah, Salt Lake City, UT, 8Cardiac Surgery, Intermountain Medical Center, Salt Lake City, UT, 9Inova Heart and Vascular Institute, Falls Church, VA, 10Mokobio, Rockville, MD
11:00 AM (315) Exosome Proteomics and Machine Learning Identify Novel Biomarkers of Primary Graft Dysfunction
N. Giangreco1, G. Lebreton2, S. Restaino3, M. Farr3, P. C. Colombo3, E. Zorn4, N. Tatonetti1, P. Leprince2, J. Kobashigawa5, B. Fine3. 1Biomedical Informatics, Columbia University, New York, NY, 2Chirurgie Thoracique et Cardiovasculaire, Pitié-Salpêtrière University Hospital, Paris, France, 3Division of Cardiology, Columbia University, New York, NY, 4Center for Translational Immunology, Columbia University, New York, NY, 5Cedars-Sinai Heart Institute, Cedars-Sinai Medical Center, Los Angeles, CA
11:15 AM (8) Engineered Mesenchymal Stromal Cell Therapy during Pig Ex Vivo Lung Perfusion and Transplant
A. I. Nykanen1, A. Mariscal1, M. Takahashi1, A. Duong1, A. Ali1, M. Chen1, A. Takahagi1, H. Gokhale1, C. Estrada2, T. Martinu1, S. Juvet1, J. Yeung1, T. K. Waddell1, M. Cypel1, M. Liu1, J. E. Davies3, S. Keshavjee1. 1Toronto Lung Transplant Program, University Health Network, Toronto, ON, Canada, 2Tissue Regeneration Therapeutics, Toronto, ON, Canada, 3Institute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, ON, Canada
11:30 AM (9) Hydrogen-Rich Preservation Solution Attenuates Lung Ischemia-Reperfusion Injury after Prolonged Cold Ischemia in a Canine Left Lung Transplant Model
H. Kayawake1, T. F. Chen-Yoshikawa1, M. Saito1, S. Hirano2, R. Kurokawa2, H. Yamagishi1, R. Okabe1, F. Gochi1, J. Tokuno1, S. Ueda1, Y. Yokoyama1, M. Ikeda1, H. Oda1, Y. Yamada1, Y. Yutaka1, D. Nakajima1, A. Ohsumi1, M. Hamaji1, H. Date1. 1Department of Thoracic Surgery, Kyoto University, Kyoto, Japan, 2MiZ Company Limited, Kamakura, Japan
11:45 AM (10) Atorvastatin Preserves Cardiac Contractility via Reducing Matrix Metalloproteinase-2 Isoforms Expression in a Diabetic Heart Model
H. Lee1, S. Lee1, S. Song2, S. Bae3, S. Kim4, J. Choi5. 1Cardiology Department, Pusan National University Hospital, Busan, Korea, Republic of, 2Nephrology Department, Pusan National University Hospital, Busan, Korea, Republic of, 3MRC for Ischemic Tissue Regeneration and Department of Pharmacology, Medical Research Institute, Pusan National University Hospital, Busan, Korea, Republic of, 4Endocrinology Department, Pusan National University Hospital, Busan, Korea, Republic of, 5Department of Cardiology, Pusan National University Hospital, Busan, Korea, Republic of
12:00 PM (11) Triptolide Attenuates Graft Inflammation During Ex Vivo Lung Perfusion
S. Burki, K. Noda, B. Philips, P. G. Sanchez, A. Kumar, J. D'Cunha. Department of Cardiothoracic Surgery, University of Pittsburgh Medical Center, Pittsburgh, PA
SESSION 02 (SYMPOSIUM): Future Shock: Great Debates in Cardiogenic Shock (Pacifica 7)
Visit the ISHLT2019 Online Program Viewer to see the full details for this session
Primary Audience: HF/HTX
Secondary Audience: MCS
Session Summary: The incidence of cardiogenic shock is increasing, leading to an emerging focus on refining our approach to shock. This symposium will provide a framework for understanding goals of treatment, defining phenotypes and profiles of shock, exploring geographical differences in management, and reviewing trends in use of temporary MCS.
Chairs: Teresa De Marco, MD and Richard Cheng, MD
10:30 AM CASE PRESENTATION: 'Gimme Gimme Shock Treatment': Acute Cardiogenic Shock Patient Transferred for Advanced Heart Failure Therapy
Adriana Torres, MD, LosCobos Medical Center, Bogota, Colombia
10:35 AM DEBATE 1: 'Culture Shock': Tissue Perfusion is More Important than Hemodynamics in Managing Cardiogenic Shock (PRO)
10:50 AM DEBATE 1: 'Culture Shock': Tissue Perfusion is More Important than Hemodynamics in Managing Cardiogenic Shock (CON)
Jennifer Cowger, MD, MS, Henry Ford Hospitals, Detroit, MI, USA
11:05 AM DEBATE 2: 'Shock Rock': One Treatment Fits All in Cardiogenic Shock (PRO)
Shelley Hall, MD, Baylor University Medical Center, Dallas, TX, USA
11:20 AM DEBATE 2: 'Shock Rock': One Treatment Fits All in Cardiogenic Shock (CON)
Rebecca Cogswell, MD, University of Minnesota, Minneapolis, MN, USA
11:35 AM DEBATE 3: 'Shock Treatment': All Patients Should Receive Temporary MCS in Cardiogenic Shock to Maximize Survival (PRO)
Pascal Leprince MD, Hôpital de La Petie Salpetriere, Paris, France
11:50 AM DEBATE 3: 'Shock Treatment': All Patients Should Receive Temporary MCS in Cardiogenic Shock to Maximize Survival (CON)
David A. Baran, MD, Sentara Heart Hospital, Norfolk, VA, USA
12:05 PM 10-min Panel Discussion
SESSION 03 (ORAL): Chronic Lung Allograft Dysfunction: Anything New? (Pacifica 10-12)
Primary Audience: LF/LTX
Secondary Audience: BSTR, PATH
Chairs: Selim M. Arcasoy, MD, MPH and Mark Greer, MB Bch
10:30 AM (12) Diffusing Capacity for Carbon Monoxide (DLCO): A Predictor of CLAD and Death after Lung Transplantation in a 20-Year Longitudinal Study
D. R. Darley1, J. Ma2, E. Huszti2, R. Ghany1, M. Hutcheon1, C. Chow1, J. Tikkanen1, S. Keshavjee1, L. G. Singer1, T. Martinu1. 1Toronto Lung Transplant Program, Toronto General Hospital, University of Toronto, Toronto, ON, Canada, 2Biostatistics Research Unit, University Health Network, Toronto, ON, Canada
10:45 AM (13) Molecular Analysis of Transbronchial and Mucosal Biopsies in Patients with CLAD
M. Parkes1, P. F. Halloran1, J. Chang1, K. S. Famulski1, J. Reeve1, R. Hachem2, P. Jaksch3, S. Juvet4, W. Klepetko3, S. Keshavjee4, D. Kreisel2, A. Roux5, G. I. Snell6, E. Trulock2, I. L. Timofte7, G. P. Westall6, K. M. Halloran1. 1University of Alberta, Edmonton, AB, Canada, 2Washington University School of Medicine, St. Louis, MO, 3Medical University of Vienna, Vienna, Austria, 4University Health Network, Toronto, ON, Canada, 5Hôpital Foch, Surenes, France, 6Monash University, Melbourne, Australia, 7University of Maryland, Baltimore, MD
11:00 AM (14) Predictive Biomarkers for Bronchiolitis Obliterans
V. Kaza1, C. Zhu1, L. Feng1, A. Reddy2, C. Lacelle3, L. Terada1, M. Manish1, S. Bollineni1, A. Banga1, F. Torres1, J. Mullins1, Q. Li4. 1UT SW Med Ctr, Dallas, TX, 2Southwest Pulmonary Associates, Dallas, TX, 3UT Southwestern Medical Center, Dallas, TX, 4Ut SW Med Ctr, Dallas, TX
11:15 AM (15) Chest CT Has Prognostic Value at BOS Diagnosis after Lung Transplantation
A. Van Herck1, A. Sacreas1, T. Heigl1, J. Kaes1, A. Vanstapel1, S. E. Verleden1, B. M. Vanaudenaerde1, W. De Wever2, G. M. Verleden1, R. Vos1. 1Lung Transplant Unit, Department of Chronic Diseases, Metabolism & Ageing, University of Leuven, Leuven, Belgium, 2Department of Radiology, University Hospitals Leuven, Leuven, Belgium
11:30 AM (16) Regulatory T Cells in Asymptomatic ISHLT Grade A1 Rejection and the Risk of Chronic Lung Allograft Dysfunction
M. White, L. Levy, S. Moshkelgosha, G. Zehong, S. Keshavjee, T. Martinu, S. Juvet. Toronto Lung Transplant Program, Toronto General Research Institute, Toronto, ON, Canada
11:45 AM (17) Emergence of a Specific Intrapulmonary CD4+ T Cell Subset Prior to the Onset of Lung Allograft Dysfunction
S. Moshkelgosha1, L. Levy1, T. Martinu1, R. Zamel1, C. Guidos2, S. Keshavjee1, J. Yeung1, S. C. Juvet1. 1Toronto Lung Transplant Program, Latner Thoracic Surgery Research Laboratories, University Health Network, Toronto, ON, Canada, 2The Hospital for Sick Children (SickKids), Toronto, ON, Canada
12:00 PM (18) Increased Hazard of Chronic Lung Allograft Dysfunction in the Presence of Persistent and Complement Fixing Donor-Specific Antibodies
C. J. Iasella1, C. R. Ensor2, M. Marrari3, M. Mangiola3, C. A. Moore4, M. R. Morrell5, J. M. Pilewski5, J. D'Cunha6, P. Sanchez6, J. F. McDyer5, A. Zeevi3. 1Department of Pharmacy and Therapeutics, University of Pittsburgh, Pittsburgh, PA, 2Department of Pharmacy, Florida Hospital, Orlando, FL, 3Department of Pathology, University of Pittsburgh, Pittsburgh, PA, 4Department of Pharmacy, University of Pittsburgh Medical Center, Pittsburgh, PA, 5Department of Medicine, University of Pittsburgh, Pittsburgh, PA, 6Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, PA
SESSION 04 (ORAL): So Wrong It's Right: The Right Ventricle and MCS (Pacifica 6)
Primary Audience: MCS
Secondary Audience: PH, PHARM
Chairs: Bastian Smack, MD and Brent Lampert, MD
10:30 AM (19) Right Ventricular Strain as a Predictor of Post-LVAD Early Right Ventricular Failure
L. W. Liang, E. Y. Birati, C. Justice, Y. Han. Hospital of the University of Pennsylvania, Philadelphia, PA
10:45 AM (20) Serial Assessment of Pulmonary Artery Pulsatility Index Provides Incremental Risk Assessment for Early Right Ventricular Failure after Left Ventricular Assist Device Implantation
M. H. Gonzalez1, J. Wagener1, A. Aggarwal2, T. Buda1, V. Menon1, M. Jacob1, W. Tang1, E. Hsich1, M. Tong3, E. Soltesz3, R. Starling1, J. Estep1, E. Joyce1. 1Cardiology, Cleveland Clinic Foundation, Cleveland, OH, 2Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH, 3Cardiothoracic Surgery, Cleveland Clinic Foundation, Cleveland, OH
11:00 AM (21) Bridging Biventricular Failure to Successful Heart Transplants: HVAD BiVAD versus TAH
A. Salimbangon1, R. Chand1, C. Lum1, D. Vucicevic2, E. DePasquale1. 1UCLA, Los Angeles, CA, 2Newark Beth Israel, Newark, NJ
11:15 AM (22) New Insights into Right Ventricular Function among Patients with Left Ventricular Assist Devices Using High Fidelity Conductance Catheters to Generate Real Time Pressure Volume Loops
W. K. Cornwell1, G. Coe2, A. Levy2, T. Tran2, M. Bradley2, K. O'Gean2, M. Ostertag2, M. Spotts3, S. Laing2, J. Lawley4, C. DeSouza5, B. Stauffer2, A. Ambardekar2, J. Pal2, G. Wolfel2, W. Kohrt2. 1University of Colorado, Denver, CO, 2University of Colorado, Aurora, CO, 3Aurora, University of Colorado, Denver, CO, 4University of Innsbruck, Innsbruck, Austria, 5University of Colorado, Boulder, CO
11:30 AM (23) Early and Late Right Heart Failure Following LVAD Implantation: Epidemiology, Natural History and Outcomes. An Analysis of the STS INTERMACS Database
C. J. Kapelios1, L. H. Lund2, C. H. Selzman3, S. L. Meyers4, A. Koliopoulou3, J. Stehlik3, O. Wever-Pinzon3, A. G. Kfoury5, J. C. Fang3, J. K. Kirklin4, S. G. Drakos3. 1National and Kapodestrian University of Athens, Athens, Greece, 2Karolinska University Hospital, Stockholm, Sweden, 3University of Utah Health & School of Medicine, Salt Lake City, UT, 4Kirklin Institute for Research in Surgical Outcomes, University of Alabama at Birmingham, Birmingham, AL, 5Intermountain Medical Center, Salt Lake City, UT
11:45 AM (24) Pectoralis Muscle Attenuation Improves the Prediction of Right Ventricular Failure after LVAD Implantation
H. Shah1, T. Murray2, J. Estep3, R. Araujo4, A. El Rafei5, B. Trachtenberg4, L. Teigen6, J. Schultz1, R. John7, C. Martin1, R. Cogswell1. 1Cardiology, University of Minnesota, Minneapolis, MN, 2Biostatistics, University of Minnesota, Minneapolis, MN, 3Cardiology, Cleveland Clinic, Cleveland, OH, 4Cardiology, Houston Methodist, Houston, TX, 5Internal Medicine, University of Minnesota, Minneapolis, MN, 6Gastroenterology Hepatology and Nutrition, University of Minnesota, Minneapolis, MN, 7Cardiothoracic Surgery, University of Minnesota, Minneapolis, MN
12:00 PM (25) Oral Milrinone for the Treatment of Right Ventricular Failure in LVAD Patients
N. Uriel1, D. Burkhoff2, G. Kim1, T. Silverstein1, J. Raikhelkar1, B. Smith1, C. Juricek1, V. Jeevanandam1, R. M. Lang3, G. Sayer1. 1University of Chicago, Chicago, IL, 2Columbia University, New York, NY, 3University of Chicago Medicine, Chicago, IL
SESSION 05 (SYMPOSIUM): Limiting the Invasiveness of the VAD Therapy: Alternative to Limited Surgical Approaches (Grand Caribbean 1-7)
Session Summary: The ISHLT 2018 Annual Meeting included the highest number of abstracts on less invasive VAD implantation approach. This symposium will evaluate the potential advantages of minimal invasive approaches for VAD implantation, the usage of ECMO instead of CPB, and the feasibility and advantages of adding minimal invasive and off-pump techniques.
Chairs: George M. Wieselthaler, MD and Marian Urban, MD
10:30 AM Influence of the Surgical Technique on Post-Operative Outcome: Is Minimal Invasive Approach the Way to Go?
Victor Pretorius, MD, UCSD Medical Center, San Diego, CA, USA
10:45 AM Q&A
10:50 AM The Alternative Approach: Should We Be Using ECMO Instead of CPB?
Julia Riebandt, MD, Medical University of Vienna, Vienna, Austria
11:10 AM Going 'Off-Pump': Does It Make a Difference?
Diyar Saeed, MD, PhD, Leipzig Heart Center, Leipzig, Germany
11:30 AM Going 'BIVAD': Acute Pitfalls and Long-Term Threats
Evgenij V. Potapov, MD, PhD, Deutsches Herzzentrum, Berlin, Germany
11:50 AM Out with the Old: Pump Replacement/Upgrade Decommissioning Explant
Carmelo A. Milano, MD, Duke University Medical Center, Durham, NC, USA
12:05 PM Q&A
SESSION 06 (ORAL): Pediatric Donor Utilization, MCS, Readmissions and More (Pacifica 3-5)
Primary Audience: PEDS
Secondary Audience: HF/HTX, MCS
Chairs: Jonathan N. Johnson, MD and Francesco Parisi, MD
10:30 AM (26) Donor Utilization in the Australian National Paediatric Heart Transplant Program: Stretching the Limits
J. Wacker1, A. Shipp1, I. Konstantinov2, J. Brink2, R. Weintraub1, J. Mathew1. 1Cardiology, The Royal Children's Hospital Melbourne, Parkville, Australia, 2Cardiac Surgery, The Royal Children's Hospital Melbourne, Parkville, Australia
10:45 AM (27) Regional Variation in Donor Refusal Rates Correlates with Poor Wait List Outcomes
R. R. Davies1, R. Butts2, M. Bano2, R. D. Jaquiss1, R. C. Kirk1. 1Pediatric Cardiothoracic Surgery, UT Southwestern - Children's Health Dallas, Dallas, TX, 2Pediatrics (Cardiology), UT Southwestern - Children's Health Dallas, Dallas, TX
11:00 AM (417) Toward a New Strategy for Pediatric Heart Allocation: High Risk Organs for Less Ill Patients?
A. K. Morrison1, C. Gowda2, R. Gajarski1, D. Nandi1. 1The Heart Center, Nationwide Children's Hospital, Columbus, OH, 2Department of Pediatrics, Division of Infectious Diseases, Nationwide Children's Hospital, Columbus, OH
11:15 AM (29) Anti-Coagulation Management in Pediatric Ventricular Assist Device: A Quality Improvement Target
C. VanderPluym1, M. O'Connor2, A. Lorts3, M. Ploutz4, D. Peng5, S. Law6, M. Zinn7, R. Niebler8, D. Rosenthal9, J. Conway10, S. Auerbach11, D. Sutcliffe12, M. Mehegan13. 1Boston Children's Hospital, Boston, MA, 2Children's Hospital of Philadelphia, Philadelphia, PA, 3Cincinnati Children's Hospital, Cincinnati, OH, 4Phoenix Children's Hospital, Phoenix, AZ, 5C.S. Mott Children's Hospital, Ann Arbor, MI, 6Morgan Stanley Children's Hospital of New York Presbyterian, New York, NY, 7Children's Hospital of Pittsburgh, Pittsburgh, PA, 8Children's Hospital of Wisconsin, Milwaukee, WI, 9Lucile Packard Children's Hospital, Palo Alto, CA, 10Stollery Children's Hospital, Edmonton, AB, Canada, 11Children's Hospital Colorado, Aurora, CO, 12Children's Health Dallas, Dallas, TX, 13Children's Hospital St. Louis, St. Louis, MO
11:30 AM (30) Role of ECMO as Bridge to VAD Therapy in Critically Ill Pediatric Patients - An Analysis of the STS Pedimacs Database
S. M. Peer1, D. A. Koehl2, R. S. Cantor2, R. A. Jonas1, P. Sinha1. 1Cardiac Surgery, Children's National Health System, Washington, DC, 2Kirklin Institute for Research in Surgical Outcomes, University of Alabama at Birmingham, Birmingham, AL
11:45 AM (31) Hospital Readmission Following Pediatric Heart Transplantation
W. T. Mahle1, K. Mason2, A. Dipchand3, M. Richmond4, C. Canter5, D. Hsu6, T. P. Singh7, R. Shaddy8, B. Armstrong2, A. Zeevi9, D. Ikle2, H. Diop10, J. Odim10, S. Webber11. 1Children's Healthcare of Atlanta, Atlanta, GA, 2Rho, Chapel Hill, NC, 3Hospital for Sick Children, Toronto, ON, Canada, 4Columbia Presbyterian, New York, NY, 5St. Louis Children's, St. Louis, MO, 6Montefiore Children's Hospital, New York, NY, 7Boston Children's Hospital, Boston, MA, 8Los Angeles Children's Hospital, Los Angeles, CA, 9Children's Hospital of Pittsburgh, Pittsburgh, PA, 10NIH, Bethesda, MD, 11Vanderbilt University School of Medicine, Nashville, TN
12:00 PM (32) Slowed Progression of Maximal Intimal Thickening by Intravascular Ultrasound after Initiation of Sirolimus
A. Putschoegl1, L. Pyle1, M. Everitt1, S. Miyamoto1, B. Pietra2, S. Auerbach1. 1Children's Hospital Colorado, Aurora, CO, 2University of Florida Health, Gainesville, FL
SESSION 07 (SYMPOSIUM): Making Co-Morbidities Great Again: Practical Updates in Co-Morbidity Management (Coral Sea)
Primary Audience: PHARM
Secondary Audience: HF/HTX, LF/LTX
Session Summary: This symposium will review management of comorbidities and primary care needs that affect heart and lung transplant recipients before and after transplant including diabetes, dyslipidemia, osteoporosis, psychiatric disorders, complimentary/alternative medicine, and immunizations/travel. Best practices and recent guideline recommendations will be presented for each topic. New and novel medications available and any pros or cons for use in the transplant population will be discussed.
Chairs: Patricia Ging, PharmD and Nicole L. Casciello, PharmD, MBA
10:30 AM What to Do When the A1C is 'BIGLY': An Update on the Management of Post-Transplant Diabetes
Jennifer L. Day, PharmD, Baptist Health Heart Failure and Transplant Institute, Little Rock, AR, USA
10:45 AM Good Lipoproteins on Both Sides: Optimizing Treatment of Dyslipidemia and Obesity
Jill C. Krisl, PharmD, Houston Methodist Hospital, Houston, TX, USA
11:00 AM Skeletons in the Closet': Diagnosis, Prevention and Treatment of Osteoporosis
David Iturbe, MD, Hospital Universitario Marques de Valdecilla, Santander, Spain
11:15 AM 'Stable Genius': Managing Mental Health After Transplant
Melissa Sanchez, BSc, Hons, Royal Brompton & Harefield NHS Foundation Trust, Harefield, Middlesex, UK
11:30 AM Combating 'Alternative Facts': Complementary and Alternative Medicine in Transplant
Teena Sam, PharmD, Baylor University Medical Center, Dallas, TX, USA
11:45 AM 'Fake News': Immunization Practices and Travel Prophylaxis
Michele Estabrook, MD, St. Louis Children's Hospital, St. Louis, MO, USA
COUNCIL MEETING: Basic Science and Translational Research (Pacifica 1-2)
COUNCIL MEETING: Nursing, Health Sciences and Allied Health (Pacifica 3-5)
COUNCIL MEETING: Pharmacy and Pharmacology (Coral Sea)
Junior Faculty Mentor Lunch (South China Sea)
COMMITTEE MEETING: IMACS Registry (Admiralty Boardroom)
SESSION 08 (ORAL): ISHLT Spotlight: Heart Transplantation in Latin America (Pacifica 7)
Secondary Audience: EEP, ID, PATH
Chairs: Are M. Holm, MD, PhD, Howard Eisen, MD and Victor Rossel, MD
12:45 PM (33) Sequential Measurement of Trypanosoma cruzi Parasitic Load in Endomyocardial Biopsies for Early Detection and Follow-up of Chagas Disease Reactivation After Heart Transplantation
L. A. Benvenuti1, A. Roggério1, A. S. Nishiya2, S. Mangini1, J. E. Levi2. 1Heart Institute (InCor), Hospital das Clínicas da FMUSP, São Paulo, Brazil, 2Fundação Pró-Sangue, Hospital das Clínicas da FMUSP, São Paulo, Brazil
12:57 PM (34) The Paradigm of Gender: Mismatch and Its Influence on Short and Long-Term Outcomes after Heart Transplantation
M. D. Gilbert1, P. A. Morejón2, M. F. Renedo2, E. F. Giordanino2, L. E. Favaloro2, R. D. Ratto2, D. O. Absi1, R. R. Favaloro1, A. M. Bertolotti1. 1Cardiovascular, Thoracic Surgery, and Intrathoracic Transplantation, Hospital Universitario Fundación Favaloro, Buenos Aires, Argentina, 2Heart Failure and Heart Transplantation, Hospital Universitario Fundación Favaloro, Buenos Aires, Argentina
1:09 PM (35) Incidence of Right Ventricular Dysfunction in Adult Patients Submitted to Heart Transplantation According to the Presence of Pre-Transplant Pulmonary Hypertension
M. M. Lensi, A. S. Ramos, J. Xavier Junior, L. B. Seguro, S. Mangini, M. S. Ávila, I. W. Campos, A. P. Duque, F. Gaiotto, S. P. Steffen, F. Bacal, F. G. Marcondes-Braga. Heart Transplant Department, Heart Institute - InCor HC FMUSP, São Paulo, Brazil
1:21 PM (36) The Effect of Donor-Recipient Heart Mass and Size Matching in Primary Graft Dysfunction Development after Heart Transplantation
1:33 PM (37) Endomyocardial Biopsy after Heart Transplantation. When is Too Late?
L. M. Guerrero Cepeda, F. G. Marcondes-Braga, D. M. Costa, R. M. Mendes, S. Duarte, J. C. Oliveira, I. Wosniack, L. F. Seguro, S. Mangini, F. Gaiotto, R. H. Santos, M. S. Avila, F. Bacal. Heart Transplantion, Instituto do Coração INCOR, São Paulo, Brazil
SESSION 09 (SYMPOSIUM): Re-Focusing the Blurry Vision: Biomarkers of Thoracic Allograft Rejection (Pacifica 1-2)
Session Summary: The goal of this symposium is to review advances in molecular diagnostic assessments and novel biomarkers in thoracic (both heart and lung) organ transplantation. This will include approaches that are being applied clinically and others that are investigational but that can provide greater insight into the pathophysiology and immunology of allograft rejection.
Chairs: Daniel Kreisel, MD, PhD and Tereza Martinu, MD
2:00 PM Donor-Derived Cell Free DNA as a Marker of Allograft Injury
Hannah Valantine, MD, National Institutes of Health, Bethesda, MD, USA
2:15 PM Q&A
2:20 PM Monitoring Immune Responses
Glen Westall, MD, PhD, Alfred Hospital, Melbourne, Australia
2:40 PM MicroRNA and Exosomes
P. Christian Schulze, MD, PhD, University Hospital, Jena, Germany
3:00 PM Through the Looking Glass: Advances in Histology
Martin Goddard, FRCS, MRCPa, Papworth Hospital, Cambridge, UK
3:20 PM Gene Expression Signatures to Monitor Graft Rejection
Jean-Paul Duong Van Huyen, MD, Hospital Necker, Paris, France
SESSION 10 (ORAL): Heart Donor Management and Allocation: Setting It Up For Success (Pacifica 7)
Chairs: Victor Rossel, MD and Jamila Kremer, MD
2:00 PM (38) Non Ischemic Heart Preservation — Results from the Safety Study
J. Nilsson1, V. Jernryd2, G. Qin3, A. Paskevicius3, T. Sjöberg3, P. Höglund4, S. Steen3. 1Skanes University Hospital Cardiothoracic Surgery, Lund, Sweden, 2Clinical Sciences Lund, Cardiothoracic Surgery, Lund University, Skane University Hospital, Lund, Sweden, 3Clinical Sciences Lund, Cardiothoracic Surgery, Lund University and Skane University Hospital, Lund, Sweden, 4Laboratory Medicine, Lund, Clinical Chemistry and Pharmacology, Lund University and Skane University Hospital, Lund, Sweden
2:15 PM (39) Donation after Circulatory Death in Heart Transplantation May Increase the Donor Pool by 20% in the U.S
O. K. Jawitz1, V. Raman1, A. Devore2, R. Mentz2, C. B. Patel2, M. Hartwig1, M. Daneshmand1, J. Schroder1, C. Milano1. 1Department of Surgery, Duke University School of Medicine, Durham, NC, 2Department of Medicine, Duke University School of Medicine, Durham, NC
2:30 PM (40) DCD Donor Hearts Recipients Compared to DBD Donor Heart Recipients Present with Comparable Systolic Left Ventricular Function and Better Myocardial Strain at 1 Year Follow Up
A. Ciarka1, A. Page2, S. Messer2, E. Pavlushkov2, S. Colah2, R. Axell2, B. Parizkova2, S. Tsui2, J. Parameshwar2, S. Large2. 1Cardiovascular Diseases, Catholic University of Leuven, Leuven, Belgium, 2of Transplantation, Papworth Hospital, NHS Foundation Trust, Cambridge, United Kingdom
2:45 PM (41) A Data-Driven Framework for Monitoring and Improving Organ Donation Awareness among Minorities Using Optimal Social Network Intervention
D. Pinheiro1, M. Murphy2, R. Iyengar2, J. Lazareff3, J. Choi4, R. Menezes5, M. Cadeiras1. 1Department of Internal Medicine, University of California, Davis, Sacramento, CA, 2Department of Medicine, University of California, Los Angeles, Los Angeles, CA, 3Center for World Health, University of California, Los Angeles, Los Angeles, CA, 4Department of Sociology, State University of San Diego, San Diego, CA, 5Department of Computer Science, University of California, Davis, Exeter, United Kingdom
3:00 PM (42) The Impact of DCD Heart Transplantation on the Waiting List: A Single Centre Experience
A. Page, R. Duehmke, S. Messer, S. Barra, M. Berman, S. Bhagra, J. Parameshwar, S. Tsui, P. Catarino, S. Pettit, S. Large. Papworth Hospital NHS Foundation Trust, Cambridge, United Kingdom
3:15 PM (43) The Benefit of Heart Transplant Among Candidates Assigned Lower Priority in the New 6-Status US Heart Allocation System
W. F. Parker1, E. S. Huang1, R. D. Gibbons2, A. S. Anderson3, M. M. Churpek1. 1University of Chicago Medicine, Chicago, IL, 2Public Health Sciences, University of Chicago Medicine, Chicago, IL, 3Northwestern Medicine, Chicago, IL
3:30 PM (44) Clinical Factors Associated with Left Ventricular Recovery in Brain Dead Cardiac Donors
J. R. Peacock, J. Ji, A. Bhatia, J. C. Hartupee, G. A. Ewald. Washington University in St. Louis, St. Louis, MO
SESSION 11 (ORAL): Chronic Lung Allograft Dysfunction: Overcoming the Hurdle? (Pacifica 10-12)
Chairs: Edward R. Garrity, Jr., MD and Cynthia J. Gries, MD, MSc
2:00 PM (45) Increased Frequency Of regulatory CD127low T Cells and of IL2+ T Cells Early after Lung Transplant is Associated with Improved Graft Survival
F. Ius1, J. Salman1, A. Knöfel1, T. Nakagiri1, W. Sommer1, T. Siemeni1, C. Kh ün1, T. Welte2, C. S. Falk3, A. Haverich1, I. Tudorache1, G. Warnecke1. 1Department of Cardiothoracic, Transplant and Vascular Surgery, Hannover Medical School, Hannover, Germany, 2Department of Respiratory Medicine, Hannover Medical School, Hannover, Germany, 3Institute of Transplant Immunology, Hannover Medical School, Hannover, Germany
2:15 PM (46) Prognostic Significance of Mesenchymal Cell Colony Forming Units in Bronchoalveolar Lavage Fluid for Restrictive Chronic Lung Allograft Dysfunction
M. P. Combs1, M. Xia2, D. S. Wheeler1, E. A. Belloli1, D. M. Lyu1, N. M. Walker1, S. Murray2, V. N. Lama1. 1Department of Medicine, University of Michigan, Ann Arbor, MI, 2Department of Biostatistics, University of Michigan, Ann Arbor, MI
2:30 PM (47) Intragraft IgG Levels and Donor-Specific anti-HLA Antibodies in Different Phenotypes of Chronic Lung Allograft Dysfunction
A. Sacreas1, J. Taupin2, A. Van Herck1, J. Kaes1, T. Heigl1, A. Vanstapel1, M. Emonds3, L. Daniëls3, R. Vos1, G. M. Verleden1, B. M. Vanaudenaerde1, A. Roux4, S. E. Verleden1. 1Leuven Lung Transplant Unit, Department of Chronic Diseases, Metabolism, and Ageing (CHROMETA), KU Leuven, Leuven, Belgium, 2Laboratoire d'Immunologie et Histocompatibilité, Saint-Louis Hospital, Paris, France, 3Histocompatibility and Immunogenetics Laboratory, Belgian Red Cross-Flanders, Mechelen, Belgium, 4Service de Transplantation Pulmonaire, Foch Hospital, Suresnes, France
2:45 PM (48) Airway Transcriptome Analysis and Immune Proteome Profiling of the Lung Allograft Reveals Novel Immune Signatures in Chronic Lung Allograft Dysfunction
C. J. Iasella1, A. Hoji2, Y. Zhang2, W. Xu2, K. Chen2, M. Brown2, E. Lendermon2, B. A. Johnson2, S. Kilaru2, M. R. Morrell2, J. M. Pilewski2, J. F. McDyer2. 1Department of Pharmacy and Therapeutics, University of Pittsburgh, Pittsburgh, PA, 2Department of Medicine, University of Pittsburgh, Pittsburgh, PA
3:00 PM (49) Host miRNA Profile of Aspergillus Colonization Resulting in CLAD in Lung Transplant Recipients
W. Gohir1, W. Klement2, L. G. Singer3, S. M. Palmer4, S. Keshavjee3, S. Husain1. 1Multi Organ Transplant Unit, Division of Infectious Diseases, University Health Network, Toronto, ON, Canada, 2Organ Donation and Transplantation, Canadian Blood Services, Ottawa, ON, Canada, 3Toronto Lung Transplant Program, University Health Network, Toronto, ON, Canada, 4Division of Pulmonary and Critical Care Medicine, Duke University, Durham, NC
3:15 PM (50) Identification and Characterization of Patients With a Mixed Phenotype of CLAD
S. E. Verleden1, J. Von der Thusen2, A. Van Herck1, B. Weynand1, E. Verbeken1, J. Verschakelen1, A. Dubbeldam1, B. Vanaudenaerde1, D. Van Raemdonck1, R. Vos1, G. Verleden1. 1KU Leuven, Leuven, Belgium, 2Universitair Medisch Centrum Rotterdam, Rotterdam, Netherlands
3:30 PM (51) Exploring Chronic Lung Transplant (LTx) Allograft Dysfunction (CLAD): The Potential Clinical Prognostic Relevance of Single Bite Transbronchial Biopsy (TBB) Microarray
G. I. Snell1, G. Westall1, Y. Cristiano1, B. J. Levvey1, L. Sullivan1, K. Halloran2, P. Halloran3. 1Lung Transplant Service, Alfred Hospital, Melbourne, Australia, 2Lung Transplant and Pulmonary Medicine, University of Alberta, Edmonton, AB, Canada, 3Department of Medicine, University of Alberta, Edmonton, AB, Canada
SESSION 12 (ORAL): When Short-Term Becomes Long-Term: Transition from Temporary to Permanent Mechanical Support (Pacifica 6)
Chairs: Maria M. Mountis, DO and Christopher T. Salerno, MD
2:00 PM (52) Outcomes of Patients Supported with ECMO as a Bridge to Durable Mechanical Circulatory Support: An Analysis of the STS Intermacs Database
R. Y. Loyaga-Rendon1, T. Boeve2, J. Tallaj3, S. Lee1, M. Leacche2, D. A. Koehl4, R. S. Cantor4, K. Lotun5, D. Acharya5. 1Cardiology Division, Spectrum Health, Grand Rapids, MI, 2Cardiothoracic Surgery Division, Spectrum Health, Grand Rapids, MI, 3Cardiovascular Division, University of Alabama at Birmingham, Birmingham, AL, 4Kirklin Institute for Research in Surgical Outcomes, University of Alabama at Birmingham, Birmingham, AL, 5Cardiovascular Diseases Division, University of Arizona Sarver Heart Center, Tucson, AZ
2:15 PM (53) Comparison of ECMO Patients Bridged to LVAD vs Bridged to Transplantation
C. Lui, C. D. Fraser, A. Suarez-Pierre, X. Zhou, K. J. Zehr, C. W. Choi, A. Kilic. Johns Hopkins University, Baltimore, MD
2:30 PM (54) Short and Long-Term Adverse Events in Patients on Temporary Circulatory Support before LVAD: An IMACS Registry Analysis
V. Ton1, J. A. Hernandez-Montfort2, R. Xie3, B. P. Meyns4, T. Nakatani5, M. Yanase6, S. Shaw7, S. Pettit8, I. Netuka9, J. Kirklin10, D. J. Goldstein11, J. Cowger12. 1University of Maryland School of Medicine, Baltimore, MD, 2The University of Texas Medical Branch-Galveston, Galveston, TX, 3The University of Alabama at Birmingham, Birmingham, AL, 4Gasthuisberg University Hopital, Leuven, Belgium, 5National Cardiovascilar Center, Osaka, Japan, 6National Cerebral and Cardiovascular Center, Osaka, Japan, 7Wythenshawe Hospital, Manchester, United Kingdom, 8Royal Papworth Hospital, Cambridge, United Kingdom, 9IKEM - Institute for Clinical and Experimental Medicine, Prague, Czech Republic, 10University of Alabama at Birmingham, Birmingham, AL, 11Montefiore Medical Center, New York, NY, 12Henry Ford Health System, Detroit, MI
2:45 PM (55) Longitudinal Impact of Temporary Mechanical Circulatory Support on Durable Left Ventricular Assist Device Outcomes: An IMACS Registry Analysis
J. A. Hernandez-Montfort1, V. Khue Ton2, R. Xie3, A. Fisher4, B. Meyns5, T. Nakatani6, I. Netuka7, S. Pettit8, S. Shaw9, M. Yanase10, J. K. Kirklin11, A. Rowe12, D. J. Goldstein13, J. Cowger14. 1The University of Texas Medical Branch - Galveston, Galveston, TX, 2University of Maryland, Baltimore, MD, 3IMACS, Birmingham, AL, 4Newcastle University, Newcastle, United Kingdom, 5UZ Leuven, Leuven, Belgium, 6Maki Hospital, Osaka, Japan, 7Institut Clinical and Experimental Medicine, Prague, Czech Republic, 8Papworth, Cambridge, United Kingdom, 9Manchester University NHS Foundation Trust, Manchester, United Kingdom, 10National Cerebral and Cardiovascular Center, Osaka, Japan, 11University of Alabama- Birmingham, Birmingham, AL, 12ISHLT Headquarters, Addison, TX, 13Montefiore, Bronx, NY, 14Cardiology, Henry Ford Hospital, Detroit, MI
3:00 PM (56) Transition from Short-Term to Durable Mechanical Circulatory Support Systems. Outcome and Patient Selection. On Behalf of ECMO-VAD Study Group
D. Saeed1, E. Potapov2, A. Loforte3, M. Morchius4, D. Schibilsky5, D. Zimpfer6, J. Riebandt6, F. Pappalardo7, M. Attisani8, A. Haneya9, F. Ramjankhan10, D. Donker10, U. Jorde11, R. Wieloch1, R. Ayala12, D. Tsyganenko2, J. Cremer9, A. Lichtenberg1, J. Gummert4. 1Cardiovascular Surgery, Heinrich-Heine University Dusseldorf, Dusseldorf, Germany, 2Deutsches Herzzentrum Berlin, Berlin, Germany, 3Bologna University, Bologna, Italy, 4Herz und Diabetes Zentrum NRW, Bad Oeynhausen, Germany, 5Cardiovascular Surgery, Freiburg University, Freiburg, Germany, 6Medical University Vienna, Vienna, Austria, 7Cardiovascular Surgery, San Raffaele Hospital, Milan, Italy, 8Cardiovascular Surgery, University of Turin, Turin, Italy, 9Cardiovascular Surgery, University Hospital Schleswig Holstein, Kiel, Germany, 10Cardiovascular Surgery, University Medical Center Utrecht, Utrecht, Netherlands, 11Montefiore Medical Center, Bronx, NY, 12Freiburg University, Freiburg, Germany
3:15 PM (57) Risk Factors for Bleeding and Thrombosis Events on Veno-Arterial Extracorporeal Life Support: An ELSO Analysis
F. R. Cabezas1, E. W. Grandin1, R. Kociol1, M. R. Mehra2. 1Beth Israel Deaconess Medical Center, Boston, MA, 2Advanced Heart Failure, Brigham and Women's Hospital, Boston, MA
3:30 PM (58) Impact of Temporary Mechanical Circulatory Support Prior to Implantation of a Ventricular Assist Device with a Follow-Up of 1 Year- A EUROMACS Analysis
D. Schibilsky1, T. de By2, J. Gummert3, F. Ramjankhan4, J. Wolfinger1, E. Potapov5, I. Netuka6, F. Beyersdorf1, M. Siepe1. 1Department of Cardiovascular Surgery, University Heart Center Freiburg, Bad Krozingen, Freiburg Germany and Medical Faculty of the Albert-Ludwigs-University Freiburg, Germany, Freiburg, Germany, 2EUROMACS, Windsor, Germany, 3Department of Cardiovascular Surgery, Heart and Diabetes Center NRW, Bad Oeynhausen, Germany, 4Department of Cardiovascular Surgery, University Medical Center Utrecht, Utrecht, Germany, 5Department of Cardiothoracic and Vascular Surgery, German Heart Institute Berlin, Berlin, Germany, 6Department of Cardiac Surgery, Institute for Clinical and Experimental Medicine, Prague, Czech Republic
SESSION 13 (SYMPOSIUM): They Tell Me I Am Irregular: Why Do They Care? Arrhythmias in LVAD Recipients (Grand Caribbean 1-7)
Session Summary: CF-LVAD patients are living longer, and cardiac implantable electronic devices and arrhythmia management have assumed a significant role. More data is available to guide management, and expert speakers including MCS & EP specialists will discuss existing data and provide recommendations regarding appropriate management of ICD/CRT and arrhythmias in LVAD recipients.
Chairs: Michael M. Givertz, MD and Stephan Schueler, MD, PhD, FRCS
2:00 PM Atrial Fibrillation and Flutter in LVAD Patients: Incidence, Significance and Management
Sean P. Pinney, MD, Mount Sinai Medical Center, New York, NY, USA
2:20 PM Optimal Device Programming and Role of Catheter and Surgical Ablation in Arrhythmia Management Post-LVAD
Joshua D. Moss, MD, UCSF Medical Center, San Francisco, CA, USA
2:40 PM DEBATE: All VAD Patients Should Have ICD and All VT Should Be Ablated (PRO)
Anique Ducharme, MD, MSC, Montreal Heart Institute, Montreal, QC, Canada
2:55 PM DEBATE: All VAD Patients Should Have ICD and All VT Should Be Ablated (CON)
Shashank S. Desai, MD, Inova Fairfax Hospital, Falls Church, VA, USA
3:10 PM DEBATE: BiV Pacing Improves Outcomes in LVAD Patients (PRO)
Gabriel Sayer, MD, University of Chicago, Chicago, IL, USA
3:25 PM DEBATE: BiV Pacing Improves Outcomes in LVAD Patients (CON)
Jens Garbade, MD, University of Leipzig Medical Center, Leipzig, Germany
SESSION 14 (SYMPOSIUM): Part of (Their) World: Discharging Patients Home with a New Device (Pacifica 3-5)
Primary Audience: NHSAH
Secondary Audience: MCS, PEDS
Session Summary: A successful discharge for patients with VAD or other supportive therapies (continuous infusions for pulmonary hypertension and heart failure patients) requires thoughtful planning and education. This symposium addresses topics geared towards helping patients successfully discharge to (and remain) home, including self-management/self-efficacy, discharge medications, avoiding readmission, preparing caregivers of patients with devices, and addressing the issues most important to patients: driving, showering, drinking, sex and traveling.
Chairs: Sarah E. Schroeder, ACNP-BC, MSN, RN, AACC and Mark E. Puhlman, DNP, ANP-C
2:00 PM I Can Go the Distance: Building Self Care and Self-Empowerment in Patients
Jesus Casida, PhD, RN, Johns Hopkins University, Baltimore, MD, USA
2:20 PM You've Got a Friend in Me: Preparing Caregivers
Jodie Lantz, MSN, RN, PCNS-BC, Children's Health Dallas, Richardson, TX, USA
2:40 PM A Spoonful of Sugar Makes the Discharge Medications Go Down
Cassandra Vale, PharmD, The Prince Charles Hospital, Queensland, Australia
3:00 PM How Far I'll Go: Preventing Returns to the Hospital
Nicola Robinson Smith, RN, Freeman Hospital, Newcastle Upon Tyne, UK
3:20 PM The Bare Necessities: The Do's and Don'ts of Living with a New Device
Wendy Gin-Sing, CNS, Hammersmith Hospital, London, UK
SESSION 15 (ORAL): Pharmacotherapy in Transplantation: Reading the Tea Leaves to Improve Outcomes (Coral Sea)
Chairs: Adam B. Cochrane, PharmD and Keyur B. Shah, MD
2:00 PM (59) Omega-3 Suppresses Gastrointestinal Bleeding by Reducing Angiopoietin-2 Expression in LVAD Patients
T. Imamura, A. Nguyen, D. Nitta, S. Kalantari, B. Smith, J. Raikhelkar, N. Narang, B. Chung, I. Ebong, L. Holzhauser, T. Fujino, C. Juricek, P. Combs, D. Onsager, T. Song, T. Ota, V. Jeevanandam, G. Sayer, G. Kim, N. Uriel. University of Chicago, Chicago, IL
2:15 PM (60) Effect of Methylene Blue Administration on Vasoplegia Following Left Ventricular Assist Device Implantation
A. Saha1, D. L. Jennings2, J. Sanchez1, A. Melehy1, M. Yuzefpolskaya3, P. C. Colombo3, M. A. Farr3, H. Takayama4, Y. Naka4, K. Takeda4. 1Columbia University Vagelos College of Physicians and Surgeons, New York, NY, 2Department of Pharmacy, Columbia University Irving Medical Center, New York, NY, 3Department of Medicine, Division of Cardiology, Columbia University Irving Medical Center, New York, NY, 4Department of Surgery, Division of Cardiac, Thoracic & Vascular Surgery, Columbia University Irving Medical Center, New York, NY
2:30 PM (61) Comparative Efficacy of Bortezomib and Carfilzomib Desensitization Protocols in Highly Sensitized Cardiac Transplant Candidates
M. Sobhanian1, J. Saltarrelli2, P. Weeks1, S. Nathan2, R. Radovancevic2, B. Kar2, I. Gregoric2. 1Memorial Hermann Hospital - Texas Medical Center, Houston, TX, 2The University of Texas Health Science Center at Houston, Houston, TX
2:45 PM (62) Mycophenolic Acid Area under the Curve Monitoring via Limited Sampling Strategy in Pediatric Heart Transplant Recipients
S. A. Crow, S. H. Dahl, J. N. Johnson. Mayo Clinic, Rochester, MN
3:00 PM (63) Association between Cumulative Pre-Transplant Amiodarone Dose and Post-Transplant Outcomes after Heart Transplantation
L. M. Lourenco1, K. Lang1, P. Simone1, S. Patel1, J. Powers2, T. Riley2, C. Murks2, B. Smith2, S. Kalantari2, J. Raikhelkar2, N. Sarswat2, G. Kim2, G. Sayer2, N. Uriel2. 1Pharmacy Services, University of Chicago Medicine, Chicago, IL, 2Cardiology, University of Chicago Medicine, Chicago, IL
3:15 PM (64) Retrospective Nested Case Control Study of the Impact of Immunosuppression on Post Transplant Malignancy among Adult Heart Transplant Patients
S. A. Crow, R. J. Bubik, N. L. Pereira, K. C. Mara, R. A. Dierkhising, S. S. Kushwaha. Mayo Clinic, Rochester, MN
3:30 PM (65) Past is Not Prologue - Immune Function Assay Results as a Predictor of Malignancy Post-Heart Transplant (HT)
T. Khuu1, M. Kamath2, M. Moore1, A. Salimbangon1, T. Daun1, A. Chang1, L. Sweet1, E. DePasquale2, A. Nsair2, R. Ardehali2, A. Baas2, M. Deng2, M. Cadeiras3, A. Ardehali4. 1Transplant Services, UCLA, Los Angeles, CA, 2Medicine, Cardiology, UCLA, Los Angeles, CA, 3Medicine, Cardiology, UC Davis, Davis, CA, 4Surgery, UCLA, Los Angeles, CA
SESSION 16 (ORAL): Junior Faculty and Trainees Clinical Case Dilemmas: The Best of the Best (Coral Sea)
Chairs: Ryan Butts, MD and Lavanya Bellumkonda, MD
4:15 PM (66) Stop the Leak! Transcatheter Aortic Valve Replacement in Pediatric VAD Patient
H. P. Tunuguntla1, I. Adachi2, A. Khan1, B. A. Elias2, S. Choudhry1, A. G. Cabrera1, J. F. Price1, W. J. Dreyer1, S. W. Denfield1, J. A. Spinner1, A. Jeewa3, A. M. Qureshi1. 1Pediatric Cardiology, Texas Children's Hospital, Houston, TX, 2Congenital Heart Surgery, Texas Children's Hospital, Houston, TX, 3Pediatric Cardiology, The Hospital for Sick Children, Toronto, ON, Canada
4:20 PM Expert Discussant for Stop the Leak! Transcatheter Aortic Valve Replacement in Pediatric VAD Patient
Christopher Almond, MD, Stanford University, Stanford, CA, USA
4:25 PM Discussion
4:32 PM (67) The Utility of CardioMEMS Implantable Hemodynamic Monitoring Device in Heartware HVAD Patient with Recurrent Gastrointestinal Bleeding
H. Singh1, V. Kittipibul2, R. Flowers2, S. V. Chaparro3. 1University of Miami Miller School of Medicine, Miami, FL, 2Department of Medicine, University of Miami Miller School of Medicine, Miami, FL, 3Cardiovascular Medicine Division, University of Miami Miller School of Medicine, Miami, FL
4:37 PM Expert Discussant for The Utility of CardioMEMS Implantable Hemodynamic Monitoring Device in Heartware HVAD Patient with Recurrent Gastrointestinal Bleeding
Robert L. Kormos, MD, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
4:49 PM (68) Inverted Lung Transplantation: Interposition of Pericardial Conduit for Pulmonary Venous Anastomosis
H. Yamamoto1, K. Miyoshi2, T. Kurosaki1, S. Otani1, M. Okazaki1, S. Sugimoto1, M. Yamane1, S. Toyooka1, T. Oto1. 1General Thoracic Surgery, Organ Transplant Center, Okayama University Hospital, Okayama, Japan, 2General Thoracic Surgery, Okayama Medical Center, Okayama, Japan
4:54 PM Expert Discussant for Inverted Lung Transplantation: Interposition of Pericardial Conduit for Pulmonary Venous Anastomosis
Christopher H. Wigfield, MD, FRCS, Advocate Christ Medical Center, Chicago, IL, USA
5:06 PM (69) Successful Bacteriophage Therapy for Treatment of Multidrug-Resistant Pseudomonas aeruginosa Infection in a Cystic Fibrosis Patient
N. Law1, C. Logan1, C. Furr2, S. Lehman2, S. Morales2, F. Rosas2, A. Gaidamaka2, I. Bilinsky2, P. Grint2, R. Schooley1, S. Aslam1. 1University of California, San Diego, San Diego, CA, 2AmpliPhi Biosciences Inc, San Diego, CA
5:11 PM Expert Discussant for Successful Bacteriophage Therapy for Treatment of Multidrug-Resistant Pseudomonas aeruginosa Infection in a Cystic Fibrosis Patient
Nicolas Mueller, MD, University Hospital Zurich, Zurich, Switzerland
5:23 PM (70) Tocilizumab for Antibody-Mediated Rejection in the Setting of Cardiac Allograft Vasculopathy
S. January1, A. Pottebaum1, D. Raymer1, K. Lavine2. 1Barnes-Jewish Hospital, St Louis, MO, 2Washington University School of Medicine, St Louis, MO
5:28 PM Expert Discussant for Tocilizumab for Antibody-Mediated Rejection in the Setting of Cardiac Allograft Vasculopathy
Jon A. Kobashigawa, MD, Cedars-Sinai Heart Institute, Los Angeles, CA, USA
5:40 PM (71) Expanding Benefits from Cardiac Resynchronization Therapy to Exercise-Induced Left Bundle Branch Block in the Setting of Advanced Heart Failure: A Case Report
F. L. Scolari, W. R. Menegazzo, A. D. Silveira, A. C. Mendes, M. Pimentel, N. Clausell, L. Goldraich. Hospital de Clínicas Porto Alegre, Porto Alegre, Brazil
5:45 PM Expert Discussant for Expanding Benefits from Cardiac Resynchronization Therapy to Exercise-Induced Left Bundle Branch Block in the Setting of Advanced Heart Failure: A Case Report
Sharon A. Hunt, MD, Stanford University Medical Center, Stanford, CA, USA
SESSION 17 (ORAL): Tolerance Is All We Need in Thoracic Transplantation (Pacifica 1-2)
Secondary Audience: HTX, LTX, PATH
Chairs: Fabio Ius, MD and Thalachallour Mohanakumar, PhD
4:15 PM (72) 31 Day Xeno Lung Recipient Survival - Progress towards the Clinic
L. Burdorf1, C. Laird2, S. Sendil2, N. O'Neill2, T. Zhang2, D. Parsell2, I. Tatarov3, Z. Abady1, B. M. Cerel1, S. Pratts1, C. J. Phelps4, D. L. Ayares4, A. M. Azimzadeh1, R. N. Pierson III1. 1Surgery, Center for Transplantation Sciences, MGH, Charlestown, MA, 2Surgery, University of Maryland, Baltimore, MD, 3Surgery, University of Maryland, Baltimore, MA, 4Revivicor, Blacksburg, VA
4:30 PM (73) Tolerance Induction by Myeloid Progenitor Cells Does Not Require Lethal Preconditioning or Hematopoietic Stem Cell Transplantation
Y. Li1, A. Sedello2, J. Domen1. 1Ward Family Heart Center, Children's Mercy Hospital and Clinics, Kansas City, MO, 2Cellerant Therapeutics, San Carlos, CA
4:45 PM (74)IL-22 Regulates Induction of Foxp3-Rich Tertiary Lymphoid Organs in Tolerant Lung Allografts
S. Tanaka1, J. M. Gauthier1, A. Fuchs1, W. Li1, R. Higashikubo1, A. Y. Tong1, A. S. Krupnick2, A. E. Gelman1, D. Kreisel1. 1Department of Surgery, Washington University in St. Louis, St. Louis, MO, 2Department of Surgery, The University of Virginia, Charlottesville, VA
5:00 PM (75) Intrapulmonary Immune Regulation by Pre-Transplant Infusion of Recipient-Derived Regulatory T Cells in a Rat Model of Ex Vivo Lung Perfusion Followed by Transplantation
E. Miyamoto, T. Martinu, D. Hwang, A. Ohsumi, K. Boonstra, B. Joe, M. Umana, M. Liu, M. Cypel, S. Keshavjee, S. Juvet. Latner Thoracic Surgery Research Laboratories, University Health Network, Toronto, ON, Canada
5:15 PM (76) PI3-Kinase Inhibition Promotes Tolerogenic CD8+ T Cell Function in Lung Transplant Recipients with a History of Cigarette Smoke Exposure
K. J. Patel1, Q. Cheng2, D. P. Allen1, C. Li1, C. Wallace1, A. Alawieh1, L. Cardenas3, J. Kilkenny1, S. N. Nadig1, M. Goddard4, J. Christie5, C. Krieg3, C. Atkinson1. 1Surgery, Medical University of South Carolina, Charleston, SC, 2Department of Surgery, Tongji Hospital, Wuhan, China, 3Microbiology and Immunology, Medical University of South Carolina, Charleston, SC, 4Pathology, Royal Papworth Hospital NHS Trust, Cambridgeshire, United Kingdom, 5Division of Pulmonary and Critical Care Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA
5:30 PM (77) Donor T and NK Cells are Derived from the Donor Lung Parenchyme and Represent Tissue-Resident Memory Cells - An Important Feature for Tolerance Development
R. Bellmàs Sanz1, A. Hitz1, B. Wiegmann2, K. Bläsing1, F. Ius2, A. Knöfel2, I. Tudorache2, M. Avsar2, D. Jonigk3, A. Haverich2, G. Warnecke2, C. Falk1. 1Institute of Transplant Immunology, Hannover Medical School, Hannover, Germany, 2Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany, 3Institute of Pathology, Hannover Medical School, Hannover, Germany
5:45 PM (78) Cardiac Allograft Vasculopathy is Linked to Impaired Generation of Regulatory M2 Macrophages
L. Holzhauser, T. Imamura, K. A. Arnold, A. Schroeder, C. Murks, J. Powers, T. Riley, G. Kim, J. Raikhelkar, B. Smith, A. Nguyen, S. Nathan, B. Chung, V. Jeevanandam, N. Narang, I. Ebong, G. Sayer, N. Uriel, A. Francis. University of Chicago, Chicago, IL
SESSION 18 (ORAL): Ex-Vivo Heart Perfusion and Preservation: Some Like It Hot - or Not! (Pacifica 7)
Chairs: Luanda P. Grazette, MD and Maryl R. Johnson, MD
4:15 PM (79) Successful Utilization of Extended Criteria Donor (ECD) Hearts for Transplantation - Results of the OCS™ Heart EXPAND Trial to Evaluate the Effectiveness and Safety of the OCS Heart System to Preserve and Assess ECD Hearts for Transplantation
J. N. Schroder1, D. D'Alessandro2, F. Esmailian3, T. Boeve4, P. Tang5, K. Liao6, I. Wang7, A. Anyanwu8, A. Shah9, K. Mudy10, E. Soltesz11, J. W. Smith12. 1Duke University Medical Center, Durham, NC, 2Massachusetts General Hospital, Boston, MA, 3Cedars-Sinai Medical Center, Los Angeles, CA, 4Spectrum Health, Grand Rapids, MI, 5University of Michigan, Ann Arbor, MI, 6University of Minnesota, Minneapolis, MN, 7Indiana University, Indianapolis, IN, 8Mount Sinai, New York, NY, 9Vanderbilt University, Nashville, TN, 10Minneapolis Heart Institute, Minneapolis, MN, 11Cleveland Clinic Foundation, Cleveland, OH, 12University of Washington, Seattle, WA
4:30 PM (80) Ex-vivo Perfusion on Marginal Donors in Heart Transplantation: Clinical Resuts and Pathological Findings
S. Sponga1, V. Ferrara1, A. P. Beltrami2, A. Bonetti2, C. Cantarutti2, A. Caragnano2, F. Ortolani2, A. Lechiancole1, R. Esposito1, C. Di Nora1, V. Tursi3, C. Nalli1, U. Livi1. 1Cardiothoracic Department, Udine University Hospital, Udine, Italy, 2Medical Area Department (DAME), Udine University Hospital, Udine, Italy, 3Udine University Hospital, Udine, Italy
4:45 PM (81) First to 50: Early Outcomes Following Heart Transplantation at Royal Papworth Hospital from Donation after Circulatory Determined Death (DCD) Donors
S. Messer, A. Page, M. Berman, S. Colah, J. Dunning, E. Pavlushkov, P. Kaul, J. Parameshwar, Y. Abu-Omar, S. Pettit, C. Lewis, A. Kydd, S. Bhagra, A. Cockell, R. Quigley, J. Baxter, C. Ellis, D. Jenkins, C. Sudarshan, A. Ali, S. Tsui, P. Catarino, S. Large. Transplant Surgery, Royal Papworth Hospital, Cambridgeshire, United Kingdom
5:00 PM (82) Cardiac Transplantation in Higher Risk Patients: Is Ex Vivo Heart Perfusion a Safe Preservation Technique? A Two Center Experience
S. V. Rojas1, F. Ius1, D. Schibilsky2, T. Kaufeld1, W. Sommer1, C. Benk2, T. Goecke1, T. Siemeni1, R. Poyanmehr1, S. Rümke1, A. Mogaldea1, D. Bobylev1, J. Salman1, M. Avsar1, I. Tudorache1, C. Bara1, F. Beyersdorf2, A. Haverich1, M. Siepe2, G. Warnecke1. 1Department of Cardiothoracic-, Transplantation- and Vascular Surgery, Hannover Medical School, Hannover, Germany, 2Department of Thoracic and Cardiovascular Surgery, University of Freiburg, Freiburg, Germany
5:15 PM (83) Keeping It Cool: Extended Myocardial Protection with Topical Cooling to Reduce PGD
S. Avtaar Singh1, S. Das De1, K. Morcos1, Y. Hegazy1, H. Al-Haideri1, S. Nair1, J. Dalzell2, H. Doshi1, N. Al-Attar1, P. Curry1. 1Cardiothoracic Surgery, Golden Jubilee National Hospital, Glasgow, United Kingdom, 2Scottish National Advanced Heart Failure Service, Golden Jubilee National Hospital, Glasgow, United Kingdom
5:30 PM (84) The First Clinical Use of a Novel Cold Storage System of Donor Hearts
N. Naito1, M. Funamoto1, R. Pierson1, M. Villavicencio1, W. Riley2, G. Lewis3, D. D'Alessandro1. 1Cardiac Surgery, Massachusetts General Hospital, Boston, MA, 2Perfusion Services, Massachusetts General Hospital, Boston, MA, 3Cardiology, Massachusetts General Hospital, Boston, MA
5:45 PM (85) Heart Ablation Avoiding Asystolia with an Always- Beating Heart
I. G. Berra1, M. L. Berra2, M. A. Lewis3, S. Berra4, A. O. Irusta5, G. Berra6, P. A. Takeuchi5. 1Heart, Lung and Kidney Transplant Team, Hospital Nacional de Pediatría JP Garrahan, Moron, Argentina, 2Clinica Medica, Hospital Nacional Alejandro Posadas, Morón, Argentina, 3Vice President, Lew Insumos e Innovaciones, Moron, Argentina, 4Facultad de Ingeniería, Universidad de Buenos Aires, Buenos Aires, Argentina, 5Design Team, Lew Insumos e Innovaciones, Moron, Argentina, 6President, Lew Insumos e Innovaciones, Moron, Argentina
SESSION 19 (SYMPOSIUM): Chronic Lung Allograft Dysfunction (CLAD): The End of the Beginning? (Pacifica 10-12)
Session Summary: The recognition that not all cases of lung allograft dysfunction could be described accurately within the bronchiolitis obliterans syndrome (BOS) terminology led to the development of a new overarching descriptor (CLAD) to embrace both obstructive and restrictive allograft dysfunction. How to detect, diagnose, and manage suspected cases is described based on sound physiological and radiological principles. Exclusion criteria are discussed as well as special circumstances.
Chairs: Christian Benden, MD and Sofya Tokman, MD
4:15 PM CLAD: Definition and Beyond
Geert Verleden, MD, Univ Hospital Gasthuisberg, Belgium, Belgium
4:30 PM CLAD Phenotypes: Why Split?
Jamie Todd, MD, Duke University, Durham, NC, USA
4:45 PM Restrictive Allograft Syndrome: Definition and Diagnosis
Masaaki Sato, MD, University of Tokyo, Tokyo, Japan
5:00 PM Restrictive Allograft Syndrome: Pathology
Jan H. von der Thüsen, MD PhD, Erasmus Medical Center, Rotterdam, Netherlands
5:15 PM Risk Factors and Prognosis of Restrictive Allograft Syndrome
Gregory I. Snell, MBBS, FRAP, MD, Alfred Hospital, Melbourne, Australia
5:30 PM CLAD Treatment: The Kingdom of the Near Dead?
Lianne G. Singer, MD, FRCPC, Toronto General Hospital, Toronto, ON, Canada
5:45 PM 15-min Panel Discussion
SESSION 20 (ORAL): The Beat Goes On: Arrhythmias and Pacing During MCS (Pacifica 6)
Secondary Audience: NHSAH
Chairs: Melana Yuzefpolskaya, MD and Joseph Rogers, MD
4:15 PM (86) Atrial Fibrillation is a Predictor of Poor Physical Capacity 6 Months after Implantation of a Full Magnetically Levitated Left Ventricular Assist Device: An Analysis from ELEVATE
K. K. Mirza1, F. Gustafsson1, Y. Pya2, S. Shaw3, A. Diegeler1, I. Netuka4, J. Lavee5, J. Garbade6, M. Morshuis7, J. Heatley8, D. Saeed9, E. V. Potapov10, J. Schmitto11, D. Zimpfer12. 1Department of Cardiology, Rigshospitalet, Copenhagen, Denmark, 2National Research Center for Cardiac Surgery, Astana, Kazakhstan, 3Southmoor Road, M23 9LT, Manchester University NHS Foundation Trust, Manchester, United Kingdom, 4Institute for Clinical and Experimental Medicine, Prague, Czech Republic, 5Heart Transplantation Unit, Leviev Heart Center, Sheba Medical Center and Sackler Faculty of Medicine, Tel Aviv University, Tel Aviv, Israel, 6Struempellstr. 39, 4289, Department of Cardiac Surgery, Heart Center Leipzig, University of Leipzig, Leipzig, Germany, 7Georgstrasse 11, 32545, Department of Cardiothoracic Surgery, Herz- und Diabeteszentrum NRW, Bad Oeynhausen, Germany, 8Abbott, Chicago, IL, 9Strümpellstrasse 39, 04289, University Department for Cardiac Surgery, Leipzig Heart Center, Leipzig, Germany, 10Department of Cardiothoracic and Vascular Surgery, German Heart Center Berlin; DZHK (German Centre for Cardiovascular Research), Partner Site Berlin, Berlin, Germany, 11Department of Cardiothoracic, Transplantation and Vascular Surgery, Medizinische Hochschule Hannover, Hannover, Germany, 12Department of Surgery, Waehringer Guertel 18–20, Division of Cardiac Surgery, Medical University of Vienna, Vienna, Austria
4:30 PM (87) Impact of Atrial Fibrillation on Mortality and Thromboembolic Complications after Left Ventricular Assist Device Implantation
V. Blumer1, M. Ortiz2, G. Hernandez3, A. Gage4, E. Joyce5, S. Chaparro1. 1University of Miami, Miami, FL, 2University of Iowa, Io, IA, 3Univ. of Miami, Miami, FL, 4Cleveland Clinic, Cleveland, OH, 5Mater Misericordiae University Hospital, Dublin, Ireland
4:45 PM (88) Peak Left Atrial Appendage Emptying Velocity Remains Reduced in Atrial Fibrillation during Continuous Flow Left Ventricular Assist Device Support
A. Rahman1, E. Tam1, L. ZHeng1, J. Fontes1, S. Forest2, S. Vukelic1, D. Sims1, J. Shin1, S. Patel1, D. J. Goldstein2, U. P. Jorde1, O. Saeed1. 1Medicine (Cardiology), Montefiore Medical Center, Bronx, NY, 2Cardiothoracic Surgery, Montefiore Medical Center, Bronx, NY
5:00 PM (89) Comparison of Amiodarone and Beta Blockers to Suppress Tachyarrhythmias in Patients with Left Ventricular Assist Devices
B. El-Sabawi1, J. V. Hull2, H. Tun3, A. S. Vaidya3, J. E. Rahman3, K. Pandya3, L. Grazette3, M. W. Fong3. 1Department of Medicine, Mayo Clinic, Rochester, MN, 2Keck School of Medicine of the University of Southern California, Los Angeles, CA, 3Division of Cardiology, Keck School of Medicine of the University of Southern California, Los Angeles, CA
5:15 PM (90) Functional Status, Quality of Life and Ventricular Tachyarrhythmias Improve with Right Ventricular Pacing Compared to Biventricular Pacing in LVAD Patients
B. Chung1, J. Grinstein2, S. Weatherford1, S. Tayazime1, D. Rodgers1, A. Nguyen1, N. Narang1, G. Kim1, J. Raikhelkar1, U. Jorde3, C. LaBuhn1, V. Jeevanandam1, G. Sayer1, N. Uriel1. 1University of Chicago, Chicago, IL, 2MedStar Health, Washington, DC, DC, 3Montefiore Medical Center, New York City, NY
5:30 PM (91) Acute Hemodynamic Effects of Different Pacing Strategies in LVAD Recipients
G. Gulati1, M. Brisco-Bacik2, C. Madias1, S. Joseph3, A. Kilic4, J. Rich5, I. Gosev6, M. Kiernan1. 1Cardiology, Tufts Medical Center, Boston, MA, 2Cardiology, Temple University Hospital, Philadelphia, PA, 3Cardiology, Baylor University Medical Center, Dallas, TX, 4Surgery, Johns Hopkins Medical Institutions, Baltimore, MD, 5Cardiology, Northwestern University, Chicago, IL, 6Surgery, University of Rochester, Rochester, NY
5:45 PM (92) Ventricular Arrhythmias in Patients with Biventricular Assist Devices
A. Lin, H. Tran, J. Hsu, K. Hoffmayer, G. Feld, E. Adler, V. Pretorius, D. Krummen, G. Ho. University of California San Diego, San Diego, CA
SESSION 21 (SYMPOSIUM): Short Term Mechanical Support: Taking the Next Leap Forward (Grand Caribbean 1-7)
Secondary Audience: HF/HTX
Session Summary: This symposium will focus on short term mechanical support with a view to optimizing results, whether as a bridge to recovery, long term mechanical support or transplant. Current and future management trends will be discussed to identify best practices for these complex patients.
Chairs: Bart Meyns, MD, PhD and Luciano Potena, MD, PhD
4:15 PM IABPs Work, But in Whom?
Jerry D. Estep, MD, Cleveland Clinic, Cleveland, OH, USA
4:35 PM In It for the Long Haul? What is the Role of ECMO in Short-Term Support?
Martin Strueber, MD, Newark Beth Israel Medical Center, Newark, NJ, USA
4:55 PM DEBATE: Six Months After the Change in the US Allocation System: It Still Makes Sense to Transplant Patients Off ECMO (PRO)
Danny Ramzy, MD, PhD, Cedars-Sinai Med Ctr, Los Angeles, CA, USA
5:10 PM DEBATE: Six Months After the Change in the US Allocation System: It Still Makes Sense to Transplant Patients Off ECMO (CON)
Jose Gonzalez-Costello, MD, Belvitge Hospital, Barcelona, Spain
5:25 PM Debate Rebuttal (PRO) - Danny Ramzy, MD, PhD
5:30 PM Debate Rebuttal (CON) - Jose Gonzalez-Costello, MD
5:35 PM Do All Roads Lead to Rome? Access Strategies for Temporary Percutaneous Mechanical Support
Jennifer A. Cowger, MD, MS, Henry Ford Hospitals, Detroit, MI, USA
SESSION 22 (SYMPOSIUM): What Do We Do? Burning Platforms in Pediatric Thoracic Transplant (Pacifica 3-5)
Secondary Audience: HF/HTX, NHSAH
Session Summary: The goal of the symposium is to address the challenges we are currently facing within the field of pediatric thoracic transplant. From donor selection to indications for transplant in the failing Fontan population, a potpourri of topics will be covered.
Chairs: Melanie D. Everitt, MD and Tajinder P. Singh, MD, MSc
4:15 PM Pediatric Heart Donors with Low Ejection Fraction - How Low Can You Go?
Claire A. Irving, MBChB, MRCPCH, MD, Children's Hospital Westmead, Sydney, Australia
4:30 PM But It's Legal Here: Addressing Legalized Marijuana and Illicit Drug Use with Thoracic Transplant Patients
Carol K. Conrad, MD, Lucille Packard Children's Hospital, Palo Alto, CA, USA
4:45 PM How Low Should We Go? Outcomes of Infant VAD and Transplant
Kathleen Simpson, MD, Washington University/St Louis Children's Hospital, St. Louis, MO, USA
5:00 PM Practical Strategies for Transitioning Our GenZ Patients
Jo Wray, PhD, Great Ormond Street Hospital, London, UK
5:15 PM Routine Use of mTOR inhibitors in Pediatric Thoracic Transplant Recipients: Show Me the Evidence
Kevin P. Daly, MD, Boston Children's Hospital, Boston, MA, USA
5:30 PM When to Refer: Advanced Cardiac Support for the Failing Fontan
Kurt R. Schumacher, MD, CS Mott Children's Hospital, Ann Arbor, MI, USA
Exhibit Hall Opening Reception (Oceana 6-12)
Council Networking Receptions
Basic Science & Translational Research (Hibiscus 1 & 2)
Pathology (Hibiscus 1-2)
Nursing, Health Sciences & Allied Health (Gardenia 2)
Pharmacy & Pharmacology (Gardenia 1)
POSTER SESSION 01
(BSTR) Poster Numbers: 573-604, 606-634
Economics, Ethics, Public Policy (Gardenia 2)
(EEP, HTX, LTX, MCS) Poster Numbers: 635-642
Heart Transplantation (Adult) (Timor Sea 1 & 2)
(HTX) Poster Numbers: 643-737
Junior Faculty Clinical Case Reports: Mechanical Circulatory Support, Infectious Diseases, Pediatrics (Banda Sea 2)
(MCS, ID, PEDS) Poster Numbers: 1245-1289
Junior Faculty Clinical Case Reports: Mechanical Circulatory Support, Pulmonary Hypertension (Banda Sea 1)
(MCS, PH) Poster Numbers: 1290-1336
Nursing, Health Sciences, Allied Health (Gardenia 2)
(NHSAH) Poster Numbers: 738-754
Pathology (Hibiscus 2)
(PATH) Poster Numbers: 605
Pharmacy and Pharmacology (Gardenia 1)
(PHARM) Poster Numbers: 755-763
MINI ORAL 01: Deciphering the Role of Antibodies and Inflammation in Thoracic Rejection (Pacifica 1-2)
Chairs: Yoshito Yamada, MD, PhD and Sebastian G. Michael, MD
6:15 PM (357) Downregulation of Alloimmunity in Lung Allograft by Eosinophils is Orchestrated by PD-L1 Dependent Contact with CD8+ T Cells
O. O. Onyema1, Y. Guo1, B. Mahgoub1, A. Manafi1, Q. Wang1, S. Criswell2, J. Lannigan3, E. A. Jacobsen4, A. E. Gelman5, D. Kreisel5, A. S. Krupnick1. 1Department of Surgery and Carter Immunology Center, University of Virginia, Charlottesviile, VA, 2Department of Cell Biology and Advanced Microscopy Core Laboratory, University of Virginia, Charlottesviile, VA, 3Flow Cytometry Core Facility, University of Virginia, Charlottesviile, VA, 4Department of Biochemistry and Molecular Biology, Mayo Clinic, Scottsdale, AZ, 5Department of Surgery, Washington University, St Louis, MO
6:20 PM (358) Donor-Derived Factors Influence NK Cell Effector Activity in a Model of Antibody-Mediated Chronic Rejection
C. M. Lin1, B. Mehrad1, R. G. Gill2. 1Medicine, University of Florida, Gainesville, FL, 2Surgery, University of Colorado, Aurora, CO
6:25 PM (359) Proteomic Profiling of Extracellular Vesicles during Acute Cellular Rejection
O. Gidlöf, I. Sukma Dewi, J. Öhman, M. Evander, T. Laurell, G. Smith. Lund University, Lund, Sweden
6:30 PM (360) Recipient CD103+ Classical Dendritic Cells Enhance Acute Rejection in Response to Airway Inflammation after Mouse Lung Transplantation
T. Watanabe, T. Martinu, K. Boonstra, J. M. Umana, M. Horie, Z. Guan, D. Hwang, M. Liu, S. Keshavjee, S. Juvet. University Health Network, Toronto, ON, Canada
6:35 PM (361) Development of Novel Murine Antibody Mediated Rejection Model after Orthotopic Lung Transplant
Y. Shiina, H. Suzuki, T. Kaiho, A. Hata, T. Yamamoto, J. Morimoto, Y. Sakairi, H. Wada, T. Nakajima, I. Yoshino. Department of General Thoracic Surgery, Chiba University Graduate School of Medicine, Chiba, Japan
6:40 PM (362) Recipient HLA-G Single Nucleotide Polymorphisms Predict Post-Lung Development of Donor Specific Antibodies
D. C. Birriel, A. Ulahannan, J. Ma, J. Lazarte, T. Martinu, L. Singer, V. Rao, S. Keshavjee, D. Delgado, J. Tikkanen, S. Juvet. UHN, Toronto, ON, Canada
6:45 PM (363) Alpha1-Antitrypsin Therapy Suppresses Acute Rejection in an Orthotopic Murine Lung Transplantation Model
T. Nakagiri1, A. Knöfel1, S. Janciauskiene2, P. Zardo1, S. Wrenger2, T. Welte2, A. Haverich1, G. Warnecke1. 1Cardiothoracic, Transplantation, and Vascular Surgery, Hannover Medical School, Hannover, Germany, 2Respiratory Medicine, Hannover Medical School, Hannover, Germany
6:50 PM (364) Circulating Exosomes with Lung Self-Antigens, Kα1Tubulin and Collagen V, and Immune Responses to Lung Self-Antigens Precedes Histological Evidence of Chronic Rejection Following Orthotopic Murine Lung Transplantation
M. Rahman, M. Sharma, W. Liu, M. A. Smith, R. M. Bremner, T. Mohanakumar. Norton Thoracic Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ
6:55 PM (365) Reconstruction of Transcriptional Programs of Monocyte to Macrophage Sequential Cell Fate Transition Using Single Cell RNA Sequencing in Sex Mis-Matched Lung Transplantation
B. O'Sullivan1, J. Powell2, S. Lukowski3, M. Tan1, P. Hopkins1, D. Chambers1. 1Queensland Lung Transplant Research, Brisbane, Australia, 2Garvan Institute, Sydney, Australia, 3Institute for Molecular Bioscience, Brisbane, Australia
7:00 PM (366) Clonal Composition and Single-Cell Characterization of T-Cell Infiltrates in Cardiac Allograft Vasculopathy
M. V. Habal1, A. Myung2, S. Rao2, S. See2, R. R. Shihab2, P. Roy2, C. Marboe3, S. Restaino1, A. S. Han2, M. Givertz4, J. C. Madsen5, L. J. Addonizio6, M. Farr1, E. Zorn2. 1Cardiology, Columbia University, New York, NY, 2Columbia Center for Translational Immunology, Columbia University, New York, NY, 3Pathology & Cell Biology, Columbia University, New York, NY, 4Cardiology, Brigham and Women's Hospital, Boston, MA, 5Surgery, Massachusetts General Hospital, Boston, MA, 6Pediatric Cardiology, Columbia University, New York, NY
7:05 PM (367) The Frequency of Tissue-Resident Donor T and NK Cells in Peripheral Blood after Lung Transplantation is Modulated by Normothermic Ex Vivo Lung
C. Falk1, B. Wiegmann2, A. Hitz1, R. Bellmas-Sanz1, K. Bläsing1, F. Ius2, C. Kühn2, M. Avsar2, I. Tudorache2, A. Haverich2, G. Warnecke2. 1Institute of Transplant Immunology, Hannover Medical School, Hannover, Germany, 2Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany
7:10 PM (368) Persisting Donor Alveolar Macrophages Have Increased Expression of Scavenger Receptor CD206 Compared to Graft-Infiltrating Recipient-Derived Macrophages Following Lung Transplantation
M. E. Snyder1, S. P. Weisberg2, T. Connors3, L. Benvenuto4, L. Shah4, H. J. Robbins4, J. L. Hook4, F. D'Ovidio5, J. Sonett5, S. Arcasoy4, D. L. Farber5. 1Medicine, University of Pittsburgh, Pittsburgh, PA, 2Pathology, Columbia University, New York, NY, 3Pediatrics, Columbia University, New York, NY, 4Medicine, Columbia University, New York, NY, 5Surgery, Columbia University, New York, NY
MINI ORAL 02: Cardiac Donor Selection: More Than Meets the Eye (Pacifica 7)
Chairs: Steven SL Tsui, MD, FRCS and Alanna A. Morris, MD
6:15 PM (369) How Big is Too Big? An Analysis of Morbidly Obese Heart Donors in the UNOS Database
E. D. Krebs, J. P. Beller, J. H. Mehaffey, N. R. Teman, J. L. Kennedy, G. Ailawadi, L. T. Yarboro. University of Virginia, Charlottesville, VA
6:20 PM (370) Label-Free Proteomics Approach Characterizes Plasma Protein Signature of Donor Brain Death
J. Lukac1, M. Saraswata2, S. Joenvääräa2, E. Holmström1, K. Dhaygude3, R. Krebs1, A. Nykänen1, R. Renkonen2, K. Lemström1. 1Cardiopulmonary Research Group, Transplantation Laboratory University of Helsinki, Helsinki, Finland, 2Mass Spectrometry Group, Transplantation Laboratory University of Helsinki, Helsinki, Finland, 3Cardiovascular Research Group, Transplantation Laboratory, University of Helsinki, Helsinki, Finland
6:25 PM (371) Donor Hormonal Thyroid Therapy is Associated with Increased Risk of Primary Graft Dysfunction after Heart Transplantation
Y. Peled, J. Lavee, E. Nachum, Y. Kassif, M. Arad, A. Kogan, D. Freimark, E. Ram. Sheba Medical Center Tel Hashomer and Tel-Aviv University, Ramat Gan, Israel
6:30 PM (372) Matchmaking Just Got Easier: Impact of Phenotypic Donor-Recipient Likeness in Open Heart Transplantation
B. D. Lo, A. Suarez-Pierre, X. Zhou, C. Lui, M. F. Hunt, G. J. Whitman, C. W. Choi, A. Kilic. Division of Cardiac Surgery, The Johns Hopkins University School of Medicine, Baltimore, MD
6:35 PM (373) Oversizing Donors - Is It Necessary for ACHD Patients?: An Analysis of the United Network for Organ Sharing Registry
D. E. Clark1, R. D. Byrne2, D. S. Burnstein3, M. R. Danter4, R. Fowler1, B. P. Frischhertz1, J. Lindenfeld1, J. A. Mazurek5, B. A. Mettler6, A. Opotowsky7, T. L. Richardson2, E. M. Sandhuas1, K. H. Schlendorf1, J. Schmeckpeper1, A. S. Shah4, A. J. Weingarten8, S. Zalawadiya1, J. N. Menachem1. 1Cardiovascular Medicine, Vanderbilt University Medical Center, Nashville, TN, 2Internal Medicine-Pediatrics, Vanderbilt University Medical Center, Nashville, TN, 3Cardiology, Children's Hospital of Philadelphia, Philadelphia, PA, 4Cardiac Surgery, Vanderbilt University Medical Center, Nashville, TN, 5Cardiovascular Medicine, University of Pennsylvania, Philadelphia, PA, 6Pediatric Cardiac Surgery, Vanderbilt University Medical Center, Nashville, TN, 7Cardiology, Harvard Medical School, Boston, MA, 8Cardiovascular Medicine, Vanderbilt University, Nashville, TN
6:40 PM (374) Mitigating the Impact of Gender Mismatch in Heart Transplantation Using BMI and BSA Ratios
Y. D. Barac, O. Jawitz, V. Raman, M. Hartwig, J. Klapper, J. Schroder, M. Daneshmand, C. Patel, C. Milano. Duke University Medical Center, Durham, NC
6:45 PM (375) Characteristics and Short-Term Outcomes of Hepatitis C Antibody Positive Organs for Heart Transplantation: UNOS Analysis
E. M. DeFilippis, R. C. Givens, A. R. Garan, F. Latif, S. W. Restaino, Y. Naka, K. Takeda, H. Takayama, P. C. Colombo, M. A. Farr, V. K. Topkara. Columbia University Medical Center, New York, NY
6:50 PM (376) Heart Transplant Recipient and Donor Age: Should the Younger Recipient Be Matched with the Younger Donor?
Y. Ravi1, N. Srikanth2, I. W. Paul3, B. A. Whitson4, S. Emani5, C. B. Sai-Sudhakar1. 1Cardiac Surgery, Scott & White, Texas A&M, Temple, TX, 2Medical Student, Saveetha Institute of Medical Sciences, Chennai, India, 3Medical Student, Sree Mookambika Institute of Medical Sciences, Kulasekaram, India, 4Cardiac Surgery, The Ohio State University, Columbus, OH, 5Internal Medicine, The Ohio State University, Columbus, OH
6:55 PM (377) Impact of Donor to Recipient Size Match on Survival after Heart Transplant Bridged with Continuous Flow Left Ventricular Assist Device
R. Yanagida1, A. Okoh2, S. Fugar3, M. Camacho4, M. Strueber4, M. J. Zucker2. 1Newark Beth Israel Medical Center, Newark, NJ, 2Department of Medicine, Newark Beth Israel Medical Center, Newark, NJ, 3Department of Medicine, Rush University Medical Center, Chicago, IL, 4Department of Cardiothoracic Surgery, Newark Beth Israel Medical Center, Newark, NJ
7:00 PM (378) Older Donors Portend Worse Survival in Older and Younger Recipients after Heart Transplant: A UNOS Database Analysis
V. Raman, O. K. Jawitz, C. White, M. Daneshmand, J. Schroder, C. Milano, M. Hartwig. Duke University Medical Center, Durham, NC
7:05 PM (379) Cardiac Allografts from Overdosed Donors: An Underutilized Resource?
N. K. Ranganath1, K. G. Phillips1, J. Malas1, B. E. Lonze2, D. E. Smith1, Z. N. Kon1, C. G. Gidea3, A. Reyentovich3, N. Moazami1. 1Cardiothoracic Surgery, NYU Langone Health, New York, NY, 2Surgery, NYU Langone Health, New York, NY, 3Medicine, NYU Langone Health, New York, NY
7:10 PM (380) Donors after Circulatory Death at the Medical College of Wisconsin and Potential for Increased Volume in Cardiac Transplantation
A. Cole1, A. Mohammed2, L. Durham1, N. Gaglianello2, D. Ishizawar2, L. Joyce1, R. Kursel2, M. Saltzberg2, D. Joyce1. 1Cardiothoracic Surgery, Medical College of Wisconsin, Milwaukee, WI, 2Advanced Heart Failure, Medical College of Wisconsin, Milwaukee, WI
MINI ORAL 03: Chronic Lung Allograft Dysfunction (Pacifica 10-12)
Secondary Audience: BSTR, PATH, PHARM
Chairs: Joshua Mooney, MD and Tanya J. McWilliams, MD, PhD
6:15 PM (1030) Early Shift of Lung Perfusion to the Unilateral Lung Predicts the Development of Unilateral Chronic Lung Allograft Dysfunction after Bilateral Living-Donor Lobar Lung Transplantation
H. Yamamoto, S. Sugimoto, T. Kurosaki, S. Otani, M. Okazaki, M. Yamane, S. Toyooka, T. Oto. General Thoracic Surgery, Organ Transplant Center, Okayama University Hospital, Okayama, Japan
6:20 PM (382) Bronchoalveolar Lavage Pentraxin 3 Levels during Clinically-Stable Minimal Acute Rejection are Associated with CLAD and Death Risk
L. Levy1, E. Huszti2, R. Ghany1, M. Ahmed1, S. Hunter1, K. Zhang1, K. Boonstra1, W. Klement1, S. Moshkelgosha1, J. Tikkanen1, L. Singer1, S. Keshavjee1, S. Juvet1, T. Martinu1. 1Toronto Lung Transplant Program, Toronto, ON, Canada, 2Biostatistics Research Unit, University Health Network, University of Toronto, Toronto, ON, Canada
6:25 PM (383) Impact of mir21 Expression in Chronic Lung Allograft Dysfunction after Lung Transplantation
N. Miyahara1, A. Benazzo1, F. Oberndorfer2, P. Jaksch1, W. Klepetko1, K. Hoetzenecker1. 1Thoracic Surgery, Medical University of Vienna, Vienna, Austria, 2Pathology, Medical University of Vienna, Vienna, Austria
6:30 PM (384) Quantiferon®-Monitor: A Potential Biomarker of Immunosuppression in Lung Transplantation
B. J. Gardiner1, Y. Cristiano2, B. J. Levvey2, G. I. Snell2, A. Y. Peleg1, G. P. Westall2. 1Infectious Diseases, Alfred Hospital & Monash University, Melbourne, Australia, 2Respiratory Medicine & Lung Transplantation, Alfred Hospital & Monash University, Melbourne, Australia
6:35 PM (385) Lung Bacterial Burden is Increased Following the Onset of Chronic Rejection
M. P. Combs, D. S. Wheeler, J. Luth, N. M. Walker, R. P. Dickson, V. N. Lama. Department of Medicine, University of Michigan, Ann Arbor, MI
6:40 PM (386) The Impact of Pharmacogenomics on Tacrolimus Dosing and Levels among Lung Transplant Recipients
A. W. Brown1, J. Peterson1, M. Fregoso1, M. Nayyar1, A. Cochrane1, J. Pluhacek1, M. Lemma1, S. Aryal1, O. A. Shlobin1, C. S. King1, R. Iyer2, J. F. Deeken2, S. D. Nathan1. 1Inova Advanced Lung Disease & Transplant, Fairfax, VA, 2Inova Translational Medicine Institute, Fairfax, VA
6:45 PM (387) Extracorporeal Photopheresis (ECP) in the Management of Chronic Lung Allograft Dysfunction
Y. Furuya1, C. Witt1, E. P. Trulock1, D. Byers1, H. Kulkarni1, L. K. Tague1, P. Aguilar1, D. Kreisel2, V. Puri2, A. Gelman2, R. Hachem1. 1Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, Saint Louis, MO, 2Division of Cardiothoracic Surgery, Washington University School of Medicine, Saint Louis, MO
6:50 PM (388) Five-Year Results of an IgA and IgM-Enriched Human Immunoglobulin G-Based Therapy for Early Anti-HLA Donor Specific Antibodies in 158 Lung-Transplanted Patients
F. Ius1, M. Verboom2, W. Sommer1, C. Müller3, M. Hallensleben2, J. Salman1, T. Siemeni1, C. Kühn1, M. Avsar1, D. Bobylev1, N. Schwerk3, A. Haverich1, I. Tudorache1, G. Warnecke1. 1Department of Cardiothoracic, Transplant and Vascular Surgery, Hannover Medical School, Hannover, Germany, 2Department of Transfusion Medicine, Hannover Medical School, Hannover, Germany, 3Department of Paediatrics, Hannover Medical School, Hannover, Germany
6:55 PM (389) Donor-Specific Antibodies and Antibody-Mediated Rejection after Alemtuzumab Induction Therapy: A Retrospective Analysis of a High-Volume Lung Transplant Center
A. Benazzo1, S. Schwarz1, S. Geleff2, D. Weber3, G. Murakozy1, C. Lambers3, B. Moser1, J. Matilla1, G. Lang3, S. Taghavi1, W. Klepetko1, K. Hoetzenecker1, P. Jaksch1. 1Thoracic Surgery, Medical University of Vienna, Vienna, Austria, 2Clinical Institute of Pathology, Medical University of Vienna, Vienna, Austria, 3Division of Thoracic Surgery, Medical University of Vienna, Vienna, Austria
7:00 PM (390) Extravascular Lung Water Quantification in Donor Lungs
K. S. Ayyat1, T. Okamoto1, H. Niikawa1, Y. Itoda1, S. Dugar1, S. Q. Latifi1, D. J. Lebovitz2, A. Moghekar1, K. R. McCurry1. 1Cleveland Clinic, Cleveland, OH, 2Lifebanc, Cleveland, OH
7:05 PM (391) Precision Proteomics as Protein Biomarker Discovery in Detecting Chronic Lung Allograft Dysfunction
H. Ghaider, M. Fakhro, S. Lindstedt. Cardiothoracic Surgery, Lund University Hospital, Lund, LUND, Sweden
7:10 PM (392) Mid-Term Results of Lung Transplantation (LTx) after Bridging with Extracorporeal Membrane Oxygenation - Influence of Concomitant Invasive Mechanical Ventilation (iMV
M. Monteagudo Vela1, D. Garcia Saez1, P. Mohite1, A. Reed2, F. De Robertis1, U. Stock1, B. Mahesh1, M. Carby2, A. Simon1, B. Zych1. 1Cardiothoracic Transplantation and Mechanical Circulatory Support, Harefield Hospital, London, United Kingdom, 2Respiratory Medicine, Harefield Hospital, London, United Kingdom
MINI ORAL 04: A Focus on Stroke (Coral Sea)
Chairs: Paolo C. Colombo, MD and Anique Ducharme, MD, MSC
6:15 PM (393) Pulmonary Effective Arterial Elastance and Pulmonary Artery Capacitance after Left Ventricular Assist Device Implantation is Associated with Hemocompatibility-Related Adverse Events
D. Nitta, T. Imamura, T. Fujino, A. Nguyen, B. Chung, D. Rodgers, J. Raikhelkar, B. Smith, L. Holzhauser, N. Narang, I. Ebong, C. Juricek, V. Jeevanandam, G. Kim, G. Sayer, N. Uriel. University of Chicago, Chicago, IL
6:20 PM (394) Decoupling between Pulmonary Artery and Wedge Pressure is Associated with Hemocompatibility-Related Adverse Events Following LVAD Implantation
T. Imamura, S. Kalantari, B. Smith, D. Rodgers, J. Raikhelkar, G. Kim, A. Nguyen, N. Narang, B. Chung, I. Ebong, L. Holzhauser, D. Nitta, T. Fujino, C. Juricek, P. Combs, D. Onsager, T. Song, T. Ota, V. Jeevanandam, G. Sayer, N. Uriel. University of Chicago, Chicago, IL
6:25 PM (396) Hemocompatibility-Related Adverse Events: Is the Burden Different among Available Centrifugal Flow Pumps?
K. A. Holst1, M. P. Weber2, V. Tchantchaleishvili2, S. Dunlay1, S. Maltais1, R. Daly1, J. Stulak1. 1Mayo Clinic, Rochester, MN, 2Thomas Jefferson University, Philadelphia, PA
6:30 PM (397) Digoxin is Associated with Decreased Survival Free from Hemocompatibility-Related Adverse Events in LVAD Patients - A Propensity Score Matched Analysis
A. Pinsino1, A. Gaudig2, K. L. Hoffman3, D. D'Angelo3, E. A. Royzman2, G. M. Mondellini2, F. Castagna2, A. M. Zuver2, A. R. Garan2, H. Takayama4, K. Takeda4, Y. Naka4, R. T. Demmer5, M. Yuzefpolskaya2, P. C. Colombo2. 1Jacobi - Albert Einstein College of Medicine, Bronx, NY, 2Department of Medicine, Columbia University Medical Center, New York, NY, 3Healthcare Policy and Research, Weill Cornell Medicine, New York, NY, 4Department of Surgery, Columbia University Medical Center, New York, NY, 5Epidemiology and Community Health, University of Minnesota, Minneapolis, MN
6:35 PM (398) Influence of Device Type on Stroke Risk in Women Undergoing LVAD Implantation
R. J. Vela1, J. Pruszynski1, A. Amin2, M. Drazner2, L. C. Huffman1, M. Peltz1. 1Cardiovascular & Thoracic Surgery, UT Southwestern Medical Center, Dallas, TX, 2Internal Medicine, UT Southwestern Medical Center, Dallas, TX
6:40 PM (399) Concentrated Factor Administration and Subsequent Stroke Rates on HeartMate II LVAD Support
J. Schultz1, A. Shaffer2, J. Misialek1, H. Shah1, R. John2, C. Martin1, T. Thenappan1, T. Alexy1, F. Kamdar1, R. Cogswell1. 1Department of Medicine, Division of Cardiology, University of Minnesota, Minneapolis, MN, 2Department of Surgery, Division of Cardiovascular Surgery, University of Minnesota, Minneapolis, MN
6:45 PM (400) Current Smoking and Increased Risk of Stroke in Patients with Left Ventricular Assist Device
S. Sherazi1, I. Goldenberg1, S. McNitt1, V. Kutyifa1, I. Gosev2, K. Wood2, L. Chen1, S. Polonsky1, H. Vidula1, J. Alexis1. 1Cardiology, University of Rochester Medical Center, Rochester, NY, 2Cardiothoracic Surgery, University of Rochester Medical Center, Rochester, NY
6:50 PM (401) Carotid Artery Blood Flow and Its Association with Stroke during Left Ventricular Assist Device Support
M. E. Kiyatkin1, A. M. Zuver1, A. Gaudig2, M. Tiburcio1, B. J. McDonnell3, M. Yuzefpolskaya1, P. C. Colombo1, E. J. Stöhr4, J. Z. Willey1. 1Columbia University Irving Medical Center, New York, NY, 2University of Münster, Münster, Germany, 3Cardiff Metropolitan University, Cardif, United Kingdom, 4Cardiff Metropolitan University, Cardiff, United Kingdom
6:55 PM (402) Different Risk Factors for Ischemic and Hemorrhagic Stroke on Continuous Flow Left Ventricular Assist Device Support
H. K. Lamba1, M. Kim1, L. Hart1, B. Chou1, C. Rao1, S. Chatterjee1, S. Sattee2, F. Cheema1, A. Civitello1, R. Delgado1, A. Nair1, A. Shafii1, G. Loor1, T. Rosengart1, O. Frazier1, J. Morgan3. 1Division of Cardiothoracic Transplantation and Mechanical Circulatory Support, Texas Heart Institute at Baylor College of Medicine, Houston, TX, 2Baylor College of Medicine, Houston, TX, 3Texas Heart Institute at Baylor College of Medicine, Houston, TX
7:00 PM (403) Strokes in LVADS. Insights from Modelling Flow in the Circle of Willis
K. Balakrishnan1, R. Krishnakumar2, S. Krishna2. 1Fortis Malar Hospital, Chennai, India, 2Engineering Design, Indian Institute of Technology, Madras, Chennai, India
7:05 PM (404) Does Left Atrial Appendage Occlusion in LVAD Patients Impact Outcomes: A Single Centre Study
F. Yu1, J. Alvarez1, R. Ribeiro1, M. B. Adamson1, F. Amin1, M. Degen1, F. Foroutan2, J. Duero Posada2, T. Yau1, R. Cusimano1, F. Billia2, C. Alba2, M. Badiwala1, V. Rao1. 1Cardiovascular Surgery, Toronto General Hospital, Toronto, ON, Canada, 2Cardiology, Toronto General Hospital, Toronto, ON, Canada
MINI ORAL 05: Do It Quick and Do It Now: ECMO Update (Pacifica 6)
Chairs: Hire Takayama, MD and Alastair Proudfoot, MBChB
6:15 PM (405) Use of Extracorporeal Membrane Oxygenation (ECMO) in Acute Myocarditis - Insights from a National Inpatient Database
M. S. Panhwar1, A. Karim1, M. Ginwalla2. 1Internal Medicine, Case Western Reserve Univ/Univ Hospitals of Cleveland, Cleveland, OH, 2Division of Cardiology, Case Western Reserve Univ/Univ Hospitals of Cleveland, Cleveland, OH
6:20 PM (406) Assessing Left Ventricular Unloading and Wall Tension to Predict the Need for Durable Mechanical Circulatory Support after Peripheral VA-ECMO
A. Prasad1, C. E. Brehm2, M. Goldenberg3, A. Ghodsizad4, M. M. Koerner5, A. El Banayosy5, K. Singbartl6. 1Anesthesiology and Perioperative Medicine, PennState Health, Hershey, PA, 2Heart and Vascular Institute, PennState Health, Hershey, PA, 3PennState College of Medicine, Hershey, PA, 4Miami Transplant Institute, University of Miami, Miami, FL, 5Advanced Cardiac Care and Transplant Institute, INTEGRIS Baptist Medical Center, Oklahoma City, OK, 6Critical Care Medicine, Mayo Clinic, Phoenix, AZ
6:25 PM (407) Bridging VA ECMO to Durable MCS: Keys to Success
A. M. El Banayosy, M. M. Koerner, D. A. Horstmanshof, A. Phancao, B. V. Jassman, C. Elkins, J. W. Long, A. El Banayosy. INTEGRIS Baptist Medical Center, Oklahoma City, OK
6:30 PM (408) Hematological Complications of Impella as an Unloading Device in Patients with Cardiogenic Shock and Veno-Arterial ECMO. A Systematic Review and Metanalysis
J. E. Pino1, E. Grajeda1, F. Ramos-Tuarez1, S. Sundaravel1, S. Sehatbakhsh2, E. Donath1, R. Chait2. 1Medicine, University of Miami/ JFK Medical Center, West Palm Beach, FL, 2Medicine, University of Miami/ JFK Medical Center, Atlantis, FL
6:35 PM (409) Lactate Predicts Mortality 12 Hours after VA ECMO Initiation
A. Melvin, B. C. Ayers, K. Wood, S. Prasad, B. Barrus, I. Gosev. University of Rochester, Rochester, NY
6:40 PM (410) Prognostic Value of Neutrophil Lymphocyte Ratio for Early Renal Failure in ECMO Patients
M. Sargin, M. T. Mete, S. B. Erdogan, H. Kuplay, M. Bastopcu, S. Akansel, M. Acarel, S. A. Aka. Cardiovascular Surgery, Siyami Ersek Hospital, Istanbul, Turkey
6:45 PM (411) Differences in Post-Thoracotomy Outcomes in Patients Implanted off ECMO
J. D. Schmitto1, M. Ozbaran2, C. Engin2, A. Simon3, V. Horvath4, J. Roussel5, M. Pac6, U. Kervan6, S. Klotz7, F. Wagner8, T. Schloeglhofer9, D. Zimpfer9. 1Cardiac Surgery, Hannover Medical School, Hannover, Germany, 2Cardiac Surgery, Ege University Medical Center, Izmir, Turkey, 3Cardiac Surgery, Royal Brompton and Harefield Hospital, London, United Kingdom, 4Cardiac Surgery, Center for Cardiovascular and Transplant Surgery, Brno, Czech Republic, 5Cardiac Surgery, University of Nantes, Nantes, France, 6Cardiac Surgery, Turkiye Yuksek Ihtisas Education & Research Hospital, Ankara, Turkey, 7Cardiac Surgery, University Hospital Luebeck, Luebeck, Germany, 8Cardiac Surgery, Uniklinik Hamburg Eppendorf, Hamburg, Germany, 9Cardiac Surgery, Medical University Vienna, Vienna, Austria
6:50 PM (412) Mid Term Survival after VA ECMO Weaning
A. Vincentelli1, N. Rousse1, V. Loobuyck1, M. Moussa2, A. Mugnier1, J. Soquet1, E. Robin2, F. Juthier1, C. Goeminne1, C. Banfi1. 1Cardiac Surgery, Centre Hospitalier Universitaire Regional de Lille, Lille, France, 2Cardiac Surgery, Anesthesiology, Centre Hospitalier Universitaire Regional de Lille, Lille, France
6:55 PM (413) Does Transport Time or Distance from Hospital Affect Survival in Extracorporeal Membrane Oxygenation (ECMO) Patients?
J. S. Nelson, A. Eisenbeiss, E. Stauder, K. Graham, R. Alharethi, W. Caine, H. Smith, B. Reid, M. McCulloch, B. Rasmusson, V. Hebl, B. Kfoury. Intermountain Medical Center, Murray, UT
7:00 PM (414) Predictors of Survival to Discharge and Ventricular Recovery after VA-ECMO Support for Acute Myocardial Infarction Complicated by Cardiogenic Shock
J. A. Fried1, M. Cevasco2, L. Witer2, A. Masoumi1, D. Brodie3, J. Griffith1, V. Topkara1, K. Clerkin1, A. Zuver1, D. Karmpaliotis1, A. Kirtane1, H. Takayama2, M. Yuzefpolskaya1, Y. Naka2, P. Colombo1, K. Takeda2, A. R. Garan1. 1Cardiology, Columbia University Medical Center, New York, NY, 2Cardiothoracic Surgery, Columbia University Medical Center, New York, NY, 3Pulmonary and Critical Care Medicine, Columbia University Medical Center, New York, NY
7:05 PM (415) Effect of Time from Cardiogenic Shock to Initiation of Complete Cardiovascular Support on Survival: "Shock to Support Time"
A. Scatola1, A. Singh1, K. Singh2, N. Singh2, P. Meraj1. 1Cardiology, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Manhasset, NY, 2New York Institute of Technology, New York, NY
7:10 PM (416) Risk and Causes of 30-Day Readmissions Following Extracorporeal Membrane Oxygenation Support for Cardiogenic Shock
N. Tashtish1, S. Al-Kindi2, M. Karnib1, C. Di Felice3, E. Zanath4, G. Oliveira2, F. Lytle4, C. Elamm2. 1Internal Medicine, University Hosptials Cleveland Medical Center, Cleveland, OH, 2Cardiovascular Medicine, University Hosptials Cleveland Medical Center, Cleveland, OH, 3Pulmonary and Critical Care, University Hosptials Cleveland Medical Center, Cleveland, OH, 4Department of Anesthesia, University Hosptials Cleveland Medical Center, Cleveland, OH
MINI ORAL 06: Pediatrics (Pacifica 3-5)
Secondary Audience: HTX, MCS
Chairs: Jacob Matthew, MD and Beth Kaufman, MD
6:15 PM (1203) Expanding the Donor Pool for Transplant Candidates with Congenital Heart Disease: Use of Recipient Total Cardiac Volumes
S. B. Shugh1, N. A. Szugye1, C. R. Villa1, F. Zafar2, R. Bryant III2, A. Lorts1, D. L. Morales2, R. A. Moore1. 1Pediatric Cardiology, The Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Cardiothoracic Surgery, The Heart Institute, Cincinnati Children's Hospital Medical Center, Cincinnati, OH
6:20 PM (418) Transplant Center Refusal Rate and Waitlist Outcomes in Pediatric Heart Transplantation
N. Baez1, R. Davies2, R. Kirk2, M. Bano2, D. Sutcliffe2, R. Jaquiss2, R. Butts3. 1Children's Medical Center, Dallas, Dallas, TX, 2Pediatric Cardiology, Children's Medical Center, Dallas, Dallas, TX, 3Pediatric Cardiology, Children's Medical Center, Dallas, Coppell, TX
6:25 PM (419) Pediatric Heart Transplant Recipients Bridged with Biventricular Assist Device Have Worse One-Year Graft Survival: An Analysis of the United Network of Organ Sharing Database
K. Watanabe1, A. Joong1, P. T. Thrush1, N. Srdanovic2, M. C. Monge1, E. Pahl1. 1Ann and Robert Lurie Children's Hospital, Northwestern University Feinberg School of Medicine, Chicago, IL, 2Biostatistics Collaboration Center, Northwestern University Feinberg School of Medicine, Chicago, IL
6:30 PM (420) Variability in Donor Selection among Pediatric Heart Transplant Providers - Results from an International Survey
J. Godown1, R. Kirk2, A. Joong3, A. Lal4, M. McCulloch5, D. M. Peng6, J. Scheel7, R. Davies8, A. I. Dipchand9, O. Miera10, J. G. Gossett11. 1Pediatric Cardiology, Monroe Carell Jr. Children's Hospital at Vanderbilt, Nashville, TN, 2Pediatric Cardiology, University of Texas Southwestern Medical Center, Dallas, TX, 3Pediatric Cardiology, Ann and Robert H Lurie Children's Hospital of Chicago, Chicago, IL, 4Pediatric Cardiology, Primary Children's Hospital, University of Utah, Salt Lake City, UT, 5Pediatric Cardiology, University of Virginia Children's Hospital, Charlottesville, VA, 6Pediatric Cardiology, C.S. Mott Children's Hospital, Ann Arbor, MI, 7Pediatric Cardiology, St. Louis Children's Hospital, St. Louis, MO, 8Pediatric Cardiothoracic Surgery, University of Texas Southwestern Medical Center, Dallas, TX, 9Pediatric Cardiology, The Hospital for Sick Children, Toronto, ON, Canada, 10Deutsches Herzzentrum Berlin, Berlin, Germany, 11UCSF Benioff Childrens' Hospitals, San Francisco, CA
6:35 PM (421) Non-Infant, Single Ventricle Patients Enjoy the Same Post-Transplant Survival as Other Congenital Heart Patients
K. W. Riggs1, J. T. Broderick1, F. Zafar1, C. Chin2, R. Bryant III1, D. L. Morales1. 1Cardiothoracic Surgery, Cincinnati Children's Hospital, Cincinnati, OH, 2Pediatric Cardiology, Cincinnati Children's Hospital, Cincinnati, OH
6:40 PM (422) Lifetime Achievement and Quality of Life in Adult Survivors of Pediatric Heart Transplant
N. T. Stanford1, J. McAllister2, L. Addonizio2, M. Richmond2, S. Law2, T. Lee2, M. Farr3, M. Gibbons2, K. Jensen2, H. Lee2, A. Rothkopf2, R. Jackson3, W. Zuckerman2. 1Department of Pediatrics, Columbia University Medical Center, New York, NY, 2Division of Pediatric Cardiology, Columbia University Medical Center, New York, NY, 3Division of Cardiology, Columbia University Medical Center, New York, NY
6:45 PM (423) De Novo Development of Antibodies to Cardiac Myosin and Vimentin in Pediatric Heart Transplant Recipients: A Single Center Pilot Study
S. Zangwill1, M. Ploutz1, S. Bansal2, T. Mohanakumar2. 1Cardiology, Phoenix Children's Hospital, Phoenix, AZ, 2Norton Thoracic Institute, St. Joseph's Hospital and Medical Center, Phoenix, AZ
6:50 PM (1185) Antithymocyte Globulin Induction is Associated with Complement Deposition in Pediatric Cardiac Transplant Biopsies
S. Ghaleb1, H. Martinez1, S. Wittekind1, D. Witte2, T. Hengehold3, C. Chin1. 1Pediatric Cardiology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 2Department of Pathology and Laboratory Medicine, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, 3University of Cincinnati College of Medicine, Cincinnati, OH
6:55 PM (425) Retransplantation: An Underutilized Resource or Only for a Select Few?
M. Vazquez Alvarez1, E. Pruitt2, D. Nandi3, M. S. Kemna4, S. Urschel5, S. C. West6, K. Y. Lin7, H. M. Lim8, T. Allain-Rooney1, A. I. Dipchand1. 1Labatt Family Heart Center, Hospital for the Sick Children, Toronto, ON, Canada, 2University of Alabama at Birmingham, Birmingham, AL, 3The Heart Center, Nationwide Children's Hospital, Columbus, OH, 4Seattle Children's Hospital, Seattle, WA, 5Stollery Children's Hospital, Edmonton, AB, Canada, 6UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, 7Children's Hospital of Philadelphia, Philadelphia, PA, 8C.S. Mott Children's Hospital, Ann Arbor, MI
7:00 PM (426) First Clinical Experience of Jarvik 2015 in North America: The New Era of Pediatric-Specific VAD Support
I. Adachi1, J. A. Spinner2, Z. Spigel1, H. Tunuguntla3, B. Elias1, E. O. McCullum1, A. G. Cabrera3, S. Tume4, W. J. Dreyer3, H. Justino3, J. S. Heinle1, C. A. Caldarone1. 1Congenital Heart Surgery, Texas Children's Hospital, Houston, TX, 2Pediatrics, Baylor College of Medicine, Houston, TX, 3Pediatric Cardiology, Texas Children's Hospital, Houston, TX, 4Critical Care, Texas Children's Hospital, Houston, TX
7:05 PM (1204) Heterogenerous Outcomes of Liver Disease after Heart Transplantation for a Failed Fontan Procedure
A. M. Ybarra1, G. Khanna2, Y. P. Turmelle1, J. M. Stoll1, C. D. Castleberry1, J. N. Scheel1, V. Exil3, R. Ameduri4, C. E. Canter1, K. E. Simpson1. 1Pediatrics, Washington University in Saint Louis School of Medicine, St Louis, MO, 2Radiology, Washington University in Saint Louis School of Medicine, St Louis, MO, 3Pediatrics, University of Iowa Carver College of Medicine, Iowa City, IA, 4Pediatrics, University of Minnesota School of Medicine, Miineapolis, MN
7:10 PM (428) Real World Data from the ACTION Quality Improvement Network - Preliminary Experience with a Magnetically Levitated Ventricular Assist Device in US Pediatric Centers
M. J. O'Connor1, A. Lorts2, C. Mascio3, D. Sutcliffe4, R. Davies4, S. Law5, P. Chai5, D. Rosenthal6, K. Maeda6, D. Nandi7, P. McConnell7, D. Morales2. 1Division of Cardiology, The Children's Hospital of Philadelphia, Philadelphia, PA, 2Cincinnati Children's Hospital, Cincinnati, OH, 3The Children's Hospital of Philadelphia, Philadelphia, PA, 4Children's Medical Center Dallas, Dallas, TX, 5Morgan Stanley Children's Hospital, New York, NY, 6Lucile Packard Children's Hospital Stanford, Palo Alto, CA, 7Nationwide Children's Hospital, Columbus, OH
Poster Session 1 Removal (Timor, Banda, Gardenia, Hibiscus)
*This schedule at a glance is updated each Friday to reflect any changes in information, including room names, session times, speaker information
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