As lead counsel, Denning has successfully represented some of the world's best-known companies in their most important patent cases, both as patent holders and accused infringers. In addition to trying over a dozen cases to jury verdict throughout the country — particularly in the patent-heavy dockets in California, Texas, and Delaware — he also has tried many cases to the bench, including Hatch-Waxman cases and Section 337 cases before the International Trade Commission.