Trained as a neuropharmacologist, his research has focused on the signaling mechanisms of serotonin receptors including understanding the specific brain regions and neurotransmitters involved in the unique properties of hallucinogenic drugs. Dr. Gresch is currently the Director of the Bioanalytical Laboratory for the Conte Center for Neuroscience Research at Vanderbilt, which seeks to understand how early brain development shapes the serotonin system and how disruptions during development can impact such disorders as anxiety, depression, schizophrenia, and autism.