His foci are pharmacology and physiology of smooth muscle, from the single-channel level all the way to the whole animal. His research explores the roles of ion channels as signaling regulators in the urinary bladder urothelium, detrusor muscle, vasculature, and sensory nerves. Ultimately, these studies aim to uncover the mechanisms responsible for bladder dysfunction that develops with stress and aging, as well as with diseases like diabetes and hypertension.