He joined the Psychophysiology Lab as a post-doctorate in 1995 and is now Professor of Clinical Neurobiology at the Department of Psychiatry at Columbia University and NYSPI. While his undergraduate work at the TU Berlin in Germany has focused on laterality of ANS/CNS function and dysfunction, his research contributions since range from methodological improvements to electrophysiology (e.g., principal components analysis of current source density as a generic and reference-free technique for ERP/EEG data analysis) to the identification of clinically-relevant functions and biomarkers in psychosis and mood disorders.