Dr. Irwin's research focuses on how exercise and weight influence cancer risk and survivorship. Dr. Irwin is the principal investigator of a number of research studies at Yale University and collaborates on various national projects and initiatives focused on exercise and cancer survivorship. She has received funding from the National Cancer Institute, American Cancer Society, Komen for the Cure, Lance Armstrong Foundation, and American Institute for Cancer Research and has published her research findings in top medical journals. Dr. Irwin also serves on various national advisory committees to develop consensus statements on physical activity, diet, weight control, and cancer prevention and control.