In 2005, Dr. Barrios joined the BC Centre for Excellence in HIV/AIDS (BC-CfE) as Assistant Director, and is also the Principal Investigator of the Pharmacovigilance Program and Co-Chair of the Committee for Drug Evaluation and Therapy at the BC-CfE. In this capacity, he leads important programs in the areas of patient safety, pharmacovigilance and continuous quality improvement. As of July 2017, Dr. Barrios is also the Acting Director of Epidemiology and Population Health at the BC-CfE. In addition to his work at the BC-CfE, Dr. Barrios is the Senior Medical Director of Vancouver Coastal Health (Community Health Services), where he is leading key health system redesign initiatives aimed at creating efficiencies and better aligning resources to population needs.