Dr. Hewlett is also the Medical Director of the Nebraska Biocontainment Unit which was selected to care for Americans affected by the recent Ebola epidemic in West Africa. Her work with the BCU allows her to collaborate with the Department of Justice and Department of Health and Human Services to ensure that personnel are always trained to be ready for any possible global health threat. Dr. Hewlett also has an interest in Orthopedic Infectious Diseases, which comprises much of her outpatient clinical practice. She attends on the inpatient General Infectious Disease service, and is an adviser for the medical student ID interest group on campus.