He is the director of the Computational Neuroscience and Adaptive Systems (CNAS) lab, which focuses on the investigation of biological and artificial systems that adapt in order to solve problems. Dr. Mailler is an NSF Career award winner, whose research in distributed problem solving has had a significant impact on the practical applicability of these techniques, having designed several best-of-breed algorithms. His methods have been used to solve problems in sensor networks, airspace management, traffic management, resource allocation, and human coordination.