She obtained her doctoral degree at Colorado State University in 1999. There she trained at the Tri-Ethnic Center for Prevention Research. She also completed a postdoctoral fellowship with the Family Research Consortium - III at the University of Washington under the joint mentorship of Drs. Ana Mari Cauce and Marion Forgatch. Dr. Domenech Rodríguez was born and raised in Puerto Rico and currently lives in Logan, UT. She has two daughters.