He has worked for several years on the effects of exercise on the autonomic nervous system in elite sports subjects and in primary and secondary prevention of cardiovascular disease. More recently, he has focused his activity on the effects of exercise on the cardiovascular and autonomic nervous systems in neurodegenerative diseases including spinal muscular atrophy (SMA) and amyotrophic lateral scoliosis (ALS) within the Neuromuscular Degeneration and Plasticity team at Paris Descartes University. He is also the head of the Sport and Exercise Science Department at the University of Evry.