Pulcino currently serves as medical director for both the UR Medicine Complex Care Center and URMC DSRIP and AHP, and is clinic director of the Intellectual and Developmental Disabilities Leadership Initiative. She specializes in the care of adults with pediatric onset conditions and has launched projects related to this specialization, such as aligning with a statewide Medicaid delivery reform, working with Eastman Institute for Oral Health on interdisciplinary education and improved access to care for adults with intellectual and developmental disabilities, and serving on the Sickle Cell Action Committee to reform regional access to care for this patient population. Pulcino makes a difference for her patients not only as a physician, but as an advocate across disciplines and systems.