As an animal physiologist, his research focuses on the functional biology of blood-feeding arthropods such as mosquitoes and ticks, which are vectors of various animal and human diseases. Dr. Paluzzi's research aims to discover regulatory hormones that control feeding, digestion, excretion, electrolyte balance, reproduction, and development. His research has important implications for understanding basic biology of organisms, aiding in the future development of new compounds to control paths of diseases.