Her research focuses on colorectal cancer screening for both average-risk and high-risk populations. Her research has involved a survey of primary care providers to further understand potential sources of variation in colorectal cancer screening rates. She is currently working with the UW Health Colon Cancer Prevention Initiative to develop and implement system-wide colorectal cancer screening interventions. She is interested in identifying patient, provider, and system barriers to colorectal cancer screening and determining if interventions targeted at these barriers are more successful and sustained over time compared to the current approach. Dr. Weiss is also interested in screening in high-risk patients with hereditary colon cancer syndromes such as Lynch Syndrome and Familial Adenomatous Polyposis.