In 1993, he founded Urban-Think Tank in Caracas, Venezuela. Since May 2010, Brillembourg has held the chair for Architecture and Urban Design at the ETH Zürich in Switzerland. An interdisciplinary practice focusing on the design and research of issues relating to architecture and urbanism; Urban Think Tank recently won the Golden Lion at the 13th Architectural Biennale in Venice for their installation and research, in collaboration with Justin McGuirk and Iwan Baan, on Torre David/ Gran Horizonte.