He received his MD/PhD from the University of Pennsylvania and residency training at MGH. He completed a clinical fellowship in Gastroenterology at MGH and his postdoctoral research training in the laboratory of Richard Young at the Whitehead Institute. As a postdoctoral fellow, he studied how TGF-beta signaling regulates transcriptional networks. This work led to the identification of long noncoding RNAs that regulate development and disease. His lab currently focuses on understanding how long noncoding RNAs regulate embryonic stem cell differentiation and liver fibrosis.