Prior to joining Columbia, Dr. Olive performed his postdoctoral studies at the University of Pennsylvania and the University of Cambridge. While there, he established a preclinical therapeutics testing facility to utilize advanced genetically engineered mouse models of pancreatic cancer for assessing therapeutics. Prior to this, Dr. Olive received a B.S. in Biology from Bucknell University in 1998 and a Ph.D. in Biology from MIT in 2005. While at MIT, he used a knock-in model of Li-Fraumeni Syndrome to support the p53 “gain-of-function” hypothesis and collaborated on the development of a mouse model of advanced lung adenocarcinoma. His laboratory now studies the response of pancreatic tumors to therapeutic intervention using mouse models of pancreatic cancer.