Her research examines social interactions mediated by communication and information technology in dyads, groups, and networks, with a particular emphasis on self-disclosure and relational communication. Among her research interests are disclosure and privacy in social media, attributional judgments, virtual groups, personal relationships, and intercultural collaboration. Natalie's work has appeared in Human Communication Research, Communication Yearbook, Communication Research, and Small Group Research, and has been recognized by several top paper awards from national and international communication conferences.