He earned a Ph.D. in Pharmacology and Cancer Biology at Case Western Reserve University, and then was a post-doctoral fellow in the laboratory of Douglas R. Green, Ph.D. at the La Jolla Institute for Allergy and Immunology and St Jude Children's Research Hospital. Dr. Chipuk then joined the faculty at the Icahn School of Medicine at Mount Sinai and was co-appointed in the Department of Dermatology, The Tisch Cancer Institute, and the Diabetes, Obesity and Metabolism Institute. His laboratory is focused on how the mitochondrial network controls survival and cell death commitment, from both mechanistic and clinical perspectives. Dr. Chipuk serves on numerous editorial boards, international scientific committees, and is also the Associate Director for Basic Science Shared Resources at the NCI-designated Tisch Cancer Center at Mount Sinai.