She started her career in 1992. Colleen worked at Fox News Magazine in from 1992-1994. She then worked as Producer at NBC News. She afterward was a correspondent for NBC News for shows such as “The Today Shows,” “NBC Nightly News” and “MNSBC” from 1996 to 2003. Dominguez later changed to sports telecaster when she joined ESPN in 2004. She in the past was seen on programs like “Sports Centre” and “Outside the Lines.”