Little kicked off her career at the El Paso Times, where she had the opportunity to write about a group of Ft. Bliss soldiers captured during the Iraq War. She has written for the Robert C. Maynard Institute for Journalism Education and blogged for Change.org's Race in America team and Bitch magazine's Race Card. School districts and social advocacy organizations have featured her writing about race in their lesson plans. Kareem has also written nearly 180 articles for ThoughtCo.