She obtained her dental degree from Nepal, M.Sc. from Singapore, and Ph.D. and M.Sc. (Endodontics) from the University of Toronto. She has received number of awards from the American Association of Endodontists and Canadian Association of Dental Research for her excellent research to improve root canal disinfection and strengthen diseased tooth. She has lectured internationally and published extensively in Endodontic literature. She serves in the Scientific Advisory Board of the Journal of Endodontics and is a reviewer for peer-reviewed journals. Dr. Shrestha has also commercialized a novel technology, Uno™ Topical Gel in partnership with Germiphene Inc. to treat teeth hypersensitivity.