Dr. Wyles graduated from the Northwestern University Feinberg School of Medicine in 1998. He completed his Internal Medicine residency and Infectious Diseases fellowship at the University of Colorado Health Sciences Center. In 2005 he moved from the University of Colorado to UCSD. Dr. Wyles' research interests include the laboratory evaluation of new antiviral therapies for Hepatitis C virus (HCV), drug resistance to HCV antivirals, and HCV viral fitness. Clinically Dr. Wyles is involved in trials of novel therapies for chronic HCV and the care of patients co-infected with HIV-1 and HCV.