She received her AB from Harvard in physics (1992), her PhD from UCLA in organic chemistry, working with Kendall N. Houk and Miguel Garcia-Garibay (1998), and she carried out postdoctoral studies with Peter S. Kim and Bruce Tidor at the Whitehead Institute and MIT from 1998-2002. Her lab is pursuing computational and experimental studies of protein-interaction specificity, including the design of protein-protein interactions.