His research focuses on the design of combinatorial and statistical algorithms for the interpretation of genomes. Recent areas of emphasis include analysis of structural variation in human and cancer genomes, network/pathway analysis of genetic variants, and phylogenetic inference of tumor heterogeneity. Dr. Raphael received an SB in Mathematics from MIT, a PhD in Mathematics from the University of California, San Diego (UCSD), and completed postdoctoral training in Bioinformatics and Computer Science at UCSD. He is the recipient of the Alfred P. Sloan Research Fellowship, the NSF CAREER award, and a Career Award at the Scientific Interface from the Burroughs Wellcome Fund.