Her research focuses on biomechanics, specifically musculoskeletal spine health and the development of low back pain. Dr. Gregory's research uses both a tissue-based (in vitro) approach as well as a human-based (in vivo) approach to improve the understanding of spine injuries, and how such injuries can be rehabilitated. Her work has earned international recognition and has been awarded two prizes from the International Society for the Study of the Lumbar Spine.