His research and teaching interests lie at the intersection of sociology, philosophy and history, and he is a member of Science and Technology Studies (STS). His current investigations focus on the ecology of AIDS research infrastructures and the shifting sociotechnical architectures and transformations in information technologies that have guided and shaped HIV/AIDS science over the past 30 years. He is a principal investigator on several National Science Foundation awards and has also been a participant in National Institutes of Health and Sloan Foundation grants studying the activities of scientists, and exploring new patterns of distributed collaboration. He frequently speaks at conferences focused on research infrastructures as well as the organization and production of scientific knowledge.