For several years, she worked for Rogelio Salmona, and in 1993 founded her own architectural practice in Bogotá. In 2006, Barco participated in establishing Fundación Rogelio Salmona; she remains its vice-president. Her aim is to communicate the importance of public space as a source of social cohesion. Diana Barco is a member of the jury for the Audi Urban Future Award 2012.