His research interests include solving practical networking and systems problems, with a focus on Software Defined Networking, data centers, clouds, and configuration management. In the past, Theophilus has conducted large scale measurement studies of data centers and enterprise networks; and he has developed several networked and distributed systems -- one of which was purchased in 2012. To date, his study on data center traffic characteristics has been used by over 15 groups to evaluate their designs and architectures.