She was a clinician in the South African public and private sector and an oral medicine and periodontology lecturer for dental and oral hygiene students at the Wits School of Oral Health Sciences for almost 8 years. She also authored several publications in the South African Dental Journal. Simitha was the 2013 recipient of the Margot Lachmann Fellowship, for excellence in cancer research, with a focus on early diagnostic biomarkers in premalignant and autoimmune conditions and their conversion rate to oral cancer. She was invited to present her findings at the 9th International Congress on Autoimmunity in Nice, France.