Her main research interest is identifying the molecular mechanisms of aging using the model organism C. elegans. Her lab investigates abnormal proteostasis stress responses, similar to those that occur as part of the normal aging process, in the context of a whole metazoan, as it ages. Her long-term aim is to develop new ways to overcome age-related proteostasis collapse and improve lifespan and healthspan. Her research combines methodologies of molecular biology, cell biology and genetics to study ER homeostasis and ageing in C. elegans.