Her research focuses on LINC complexes - macromolecular complexes that span the nuclear envelope to physically couple the nucleus and the cytoskeleton. These molecular bridges allow the cytoskeleton to regulate nuclear position within the cell. In addition, they provide a mechanism for signals to be mechanically transduced between the cytoplasm and nucleus. Her research includes investigating how the association of DNA double strand breaks with the nuclear periphery (and in particular the LINC complex) impacts genome integrity. Her group also investigates the role that the nucleus plays in tissue level mechanics, particularly focusing on the skin, and has developed live-cell and force spectroscopy assays to define the mechanical behaviour of nuclei. She is the recipient of the NIH New Innovator Award and was named a Searle Scholar in 2011.