Her main research interests concern responsible innovation in the field of biotechnology and synthetic biology: how can the societal debate on biotechnology and synthetic biology be integrated in innovation trajectories? Lotte has worked as a researcher in the department of Philosophy at DUT, where she also received her PhD. Her PhD concerned societal decision making on technological risks. Lotte also worked as a researcher at the Rathenau Institute, focusing on the bioeconomy, and as a freelance researcher in China.