His methodological research interests involve longitudinal data analysis with specific emphasis on extensions of epidemiological study designs for longitudinal data as well as the construction and evaluation of prognostic models using electronic health records data. He has worked on a variety of collaborative research projects including: health effects of air pollution on children with asthma, evaluation and improvement of a pre-emptive genotyping program for personalizing cardiac medication treatments. Other collaborative work has focused on the mechanisms by which high body mass increases risk for kidney injury following thoracic surgery, and the role of social and environmental factors on outcomes and readmission risk in patients with acute coronary syndrome.