He completed his PhD under the supervision of Prof. Joseph Sung in the Department of Medicine and Therapeutics at CUHK in 2002 and completed post-doctoral training characterizing the roles of cyclooxygenase-2 in hepatitis B-induced hepatocarcinogenesis. From 2004 to 2007, he was trained as a post-doctoral researcher in Prof. Tim Huang’s lab at Ohio State University where he developed an integrated genome-wide and bioinformatics approach to interrogate gene regulatory network in cancer.