She is an expert on the structure-based computational manipulation of proteins and their interactions. She has cochaired the area of protein structure and function at major bioinformatics conferences, such as ISMB and ECCB, in the last years. She received her PhD degree in computational structural biology in 2000 from the Hebrew University in Jerusalem, Israel. She then joined the group of David Baker in the Department of Biochemistry in Seattle, Washington, where she developed tools for the accurate structural modeling of protein-protein interactions and their manipulation through computational design. In 2005, she returned to Israel and started her own group at the Hebrew University, which focuses on various aspects of the basic energetic and evolutionary principles that govern protein-protein interactions, in particular those mediated by peptides.