Dr. Malebranche provides medical care to patients at the Ponce Infectious Disease Center, a local clinic that focuses on comprehensive care to uninsured patients living with HIV/AIDS. He also supervises medical providers-in-training at the Primary Care Center at Grady Memorial Hospital in downtown Atlanta. Additionally, Dr. Malebranche conducts research exploring the social, structural, and cultural factors influencing sexual risk behavior and HIV testing practices of Black men, particularly among men who have sex with men (MSM).