Mike received his PhD from UCSD in 2004, his dissertation research included some of the first evidence for brain somatic mosaicism. After post-doctoral training at Harvard Medical School and Stanford University, he was awarded a Crick-Jacobs Junior Fellowship from the Salk Institute. At Salk, Mike worked with Dr. Fred H. Gage to develop single cell approaches to study neuronal genomes and found that large copy number variants are common contributors to brain somatic mosaicism. His laboratory uses primary human neurons and human induced pluripotent stem cell-derived neurons to understand the cause and consequence of mosaicism among neuronal genomes.