His research focuses on the integration of microelectronics, microfluidics, nanomaterials and molecular targeting, and their application to medicine. This multidisciplinary approach enables Issadore's lab to explore new technologies to bring medical diagnostics from expensive, centralized facilities, directly to clinical and resource-limited settings for applications including early detection of pancreatic cancer, tuberculosis diagnosis in patients co-infected with HIV, and prognosis of traumatic brain injury. His academic background in electrical engineering and applied physics (PhD, Harvard 2009) and his research experience in a hospital research laboratory (MGH) have prepared him to work and collaborate effectively on these inherently cross-disciplinary problems.