Mandy received her undergraduate degree from the University of Washington. She worked as a nurse at Seattle Children's Hospital with the Hematology/Oncology Department before going on to be a nurse working specifically with the brain tumor population. She went on to receive her master's degree from University of Washington as a Pediatric Nurse Practitioner. Since obtaining her masters degree (2009), Mandy has been a member of the Neurosurgery team at Seattle Children's.