His main areas of research are applied ethics (especially the ethics of technology), ethical theory, and the history of ethics. More specifically, he has recently published on love-relationships and biomedical enhancements, sex robots, motivation-enhancements, accident-algorithms for self-driving cars, deep brain stimulation, happiness and well-being, meaning in life, and interpersonal respect and moral reasoning. Nyholm’s work also focuses on the ethics of automated driving, human-robot collaboration, deep brain stimulation (including its effect on the self), and disability and the goods of life. He is especially interested in how robotization and other types of automation affect traditional human values, as well as in existential questions raised by new technological developments.