Dr. DeRenne received his MD from Indiana University, School of Medicine in Indianapolis. He completed an internship at Memorial Hospital of South Bend in South Bend, Indiana and his residency in Anatomic and Clinical Pathology at the University of California Davis, Sacramento Medical Center. He then went on to complete a research fellowship in Cardiovascular Pathology at the Mayo Graduate School of Medicine in Rochester, Minnesota and a Surgical Pathology Fellowship in the Department of Pathology at The Ohio State University.