Upon completing his B.S. degree in electrical engineering, he finished medical school and underwent an internship and residency in Neurological Surgery at the University of Kansas. He is chief of Neurosurgery at Frederick Memorial Hospital and has served as vice-chief and as chief of the Department of Surgery. Dr. Yalamanchili has served on several boards of local community charities and agencies including the Red Cross. He served in the U.S. Naval Reserve as a lieutenant commander. He is a member of the American Association of Neurological Surgeons, Congress of Neurological Surgeons, and the CyberKnife Society.