Buehler�s research focuses on bottom-up modeling and simulation of structural and mechanical properties of biological, bio-inspired, and synthetic materials across multiple scales, with a specific focus on materials failure from a nanoscale and molecular perspective. Buehler has published more than 190 articles on computational materials science, nanotechnology, and nanoscience; authored two monographs; and given several hundred invited, keynote, and plenary talks across the world. He was cited as one of the top engineers in the United States between the ages of 30-45 through invitation to the National Academy of Engineering-Frontiers in Engineering Symposium of the National Academy of Engineering.