Dr. Cambronne has a longstanding interest in the molecular mechanisms that underlie physiology and disease. A theme throughout her work includes the development of new molecular tools to address previously unattainable questions. The current research focus of the Cambronne group is to understand how changes in free nicotinamide adenine dinucleotide (NAD+) levels contribute to the progression and onset of age-related diseases. Under her direction, a collaborative team composed of members from the Goodman and Cohen labs developed a genetically-encoded fluorescent biosensor to monitor subcellular free NAD+ regulation in cells.