He is the Director of the Cardiac Psychiatry Research Program at Massachusetts General Hospital, and his team is focused on improving the mental and physical health of patients with heart disease and other medical conditions. Their program has begun to develop team-based approaches to depression and anxiety disorders in patients hospitalized for heart problems, and they are also developing positive psychological interventions to promote healthy lifestyle and well-being in persons with medical illness. Dr. Huffman has over 120 peer-reviewed publications, and his team is composed of psychiatrists, psychologists, cardiologists, diabetologists, social workers, nurses, and research fellows. He is a Greater Good Science Center gratitude research grant recipient.