His research focuses on corporate tax policy, the interactions of financial and tax reporting, and the behavior of loss firms. Plesko joined the University of Connecticut in 2005 after nine years on the faculty of the MIT Sloan School of Management. While at Sloan, Plesko received both school and institute-wide teaching awards for the first-year MBA accounting class. He has also served on the faculty of the John F. Kennedy School of Government at Harvard University, the International Tax Program at the Harvard Law School, and Northeastern University.