His Lab is particularly interested in how commensal microbes help resist, and ultimately respond to, colonization by human pathogens. An active area of research is the longitudinal study of cholera infections among residents of Dhaka, Bangladesh. Primary research questions include: Can enteric microbial communities predict an individual’s susceptibility to cholera? Why do bacterial ecological successions follow cholera infection? What long-term effects do infection and treatment have on commensal gut microbes? The David Lab is also broadly interested in developing new modeling and visualization tools for time-series of complex microbial communities, as well as exploring the ecology of human microbiota in the developing world.