Dr. Coleman’s research focus is on evaluating treatments and techniques central to the surgical care of patients with urologic cancers. He is investigating the unique mechanisms of a novel light-activated phototherapeutic agent, WST-11, with the goal of developing this form of therapy for the treatment of locally and regionally advanced malignancy. Dr. Coleman is also leading a phase II study of neoadjuvant chemotherapy for high-risk transitional cell carcinomas of the renal pelvis and ureter and a phase III trial evaluating the role of mannitol in the mitigation of nephron damage from renal ischemia during kidney surgery.