He directs the Informatics and Visualization Research Laboratory in SILS and leads the Center for Research in Digital Libraries at UNC. His primary research interests are in scholarly communications, digital libraries, human computer interaction, information searching, information visualization and bioinformatics. He has published over 80 journal articles across a number of disciplines. He has developed a number of innovative technologies including the standardization of medical image displays, real–time 3D volume visualization for surgical planning, and capturing and sharing museum exhibits as virtual realities. His current interest is in studying ways to globally share collaborative annotations for scientific research in the NeoNote project.