His main research interests are in the area of social networks, recommender systems, and user profiling. De Meo has a PhD in systems engineering and computer science from the University of Calabria. His PhD thesis was selected as the Best Italian PhD thesis in Artificial Intelligence by the AI*IA (Italian Association for Artificial Intelligence). He has been the Marie Curie Fellow at Vrije Universiteit Amsterdam. He has extensively published on top Computer Science Journals like Communications of the ACM, IEEE Transactions on Knowledge and Data Engineering, ACM Transactions on Internet Technology, ACM Transactions on Intelligent Systems, IEEE Transactions on Systems, Man and Cybernetics, Information Systems.