She received her medical degree from the University of California, Irvine, and completed her residency in Internal Medicine at the Massachusetts General Hospital in Boston, Massachusetts. She completed her fellowship in Gastroenterology and Hepatology at John H. Stroger Jr. Hospital of Cook County in Chicago, Illinois. Lee's clinical focus is on colorectal disorders, colon cancer screening and surveillance, and advanced polypectomy. Her research interest is in colorectal cancer detection and prevention with an emphasis on quality and access, in particular, amongst the underserved minority population. ​