Tig was exploring how she might have a baby with medical assistance and her comedy career was picking up with gigs on late night shows, a TV pilot, and a movie. In the midst of filming she collapsed and was rushed to a hospital where she was diagnosed with C. Diff. This gastrointestinal illness caused her to lose over 20 pounds in a couple weeks and she nearly died. By some stroke of fortune or grace, Tig recovered, but soon after her mother unexpectedly died. Shortly after that, she was diagnosed with breast cancer. A short time later she was scheduled to do a stand up act at the Largo in Los Angeles. Tig felt afraid and defeated. She had just received her diagnosis and had no idea whether she would survive the ordeal and telling jokes in front of a room of strangers did not seem like the most natural thing for her to do given her circumstances.