Her main research interest is on the understanding of the biological underpinning of the clinical phenomenon of psychosis ranging from symptoms to clinical outcomes. Psychosis is one of the most severe and chronic mental illness, a condition that has huge impact to patients, their family and the society Currently Dr Chan’s main research focuses are on the understanding the development of treatment resistant schizophrenia, development of psychotic-like experiences in general population and symptoms of psychosis including lack of insight and delusion from a biological and neurocognitive perspective.