His group operates a two-pronged research program. The first thrust of their research is to study the fundamental properties of protein-protein interactions, and the second is to create synthetic disruptors of certain protein-protein interactions that are known to drive particularly aggressive cancers. The group uses synthetic chemistry, molecular design by computational modelling, and a variety of biophysical assays for determining the activities of synthesized compounds. These efforts are anchored by a basic understanding of the chemical and physical properties of the molecules involved. The CNC-IUPAC Travel Award will fund Dr. Hof’s attendance at the International Conference on Physical Organic Chemistry in Durham, UK, in September 2012.