Koch Institute for Integrative Cancer Research at MIT. She is currently an Associate Member of the Broad and the Director of Transcriptional Chemical Biology in the Broad Institute’s Chemical Biology Program. Her research group aims to discover and develop functional small-molecule probes of transcriptional regulators, including chromatin modifying enzymes and oncogenic transcription factors. Validated probes may be used to advance the understanding of transcription in development and disease. Selected probes may be developed into imaging agents, diagnostic tools, or therapeutic leads.