She has worked in the area of iron homeostasis and neurodegeneration for the past decade. At MGH, she and her colleagues were the first to discover an iron response element in the 5’UTR of the, Amyloid precursor protein mRNA and in several other neurodegenerative disease associated genes. High through put screens using the 5’UTRs of these mRNAs have landed several small molecules that modulate Iron homeostasis.