She also serves as Director of Research in the Center for Weight, Eating and Lifestyle Science (WELL Center). Her research interests and expertise lie in weight management, physical activity promotion and dietary change. She specializes in developing and evaluating behavioral interventions for obesity, including those that are rooted in traditional and acceptance-based behavioral principles. Butryn has been funded as a principal investigator or co-investigator on 8 NIH-funded clinical trials in the areas of eating and weight. She has authored over 75 peer-reviewed manuscripts, co-authored two books, and edited one book. She serves as a member of the NIH PRDP study section and as an editorial board member for the journal Obesity Science & Practice.