She shot to repute as a Calendar girl and made her film debut with the Telugu film Rey, starring Sai Dharam Tej. She has earlier scorched the pages of Kingfisher Calendar. Saiyami has made a large debut in bollywood with the film Mirzya. Kher is the granddaughter of yesteryear actress Usha Kiran and niece of Tanvi Azmi. Her mother Uttara Mhatre Kher changed into an ex leave out India. As according to the reports, Saiyami is in a courting with a man who isn’t from this industry.