He studied medicine at the University of Cambridge where he also gained a PhD for a thesis entitled The cone dystrophies. Matthew's clinical training was undertaken at Sydney Eye Hospital, Australia, the University of British Columbia, Vancouver, Canada, Moorfields Eye Hospital, London and the the Nuffield Laboratory of Ophthalmology/Oxford Eye Hospital. He is currently a consultant vitreoretinal surgeon at Sydney Eye Hospital and an Associate Professor of Ophthalmology at the University of Sydney, where he holds a Career Development Award from the Foundation Fighting Blindness. He is an honorary clinical research associate in Professor Robert MacLaren’s group where his work is primarily directed at quantifying photoreceptor function in choroideremia patients following gene therapy.