Dr Yeo graduated from the National University of Singapore, and went on to complete an internal medicine residency at the University of Hawaii as well as an infectious disease fellowship at the University of Utah. He did his PhD at the Menzies School of Health Research and University of Queensland on the treatment and pathogenesis of severe malaria based in Indonesia Papua. Upon completion of his PhD, he worked as a research fellow at the Menzies School of Health Research and as an infectious physician at Royal Darwin Hospital in Australia.