He is currently leading the development of a simulation platform to derive “what-if” results from Global Burden of Disease estimates and is engaged in methodological and operational research on verbal autopsy. Dr. Flaxman has previously designed software tools such as DisMod-MR that IHME uses to estimate the Global Burden of Disease, and the Bednet Stock-and-Flow Model, which has produced estimates of insecticide-treated net coverage in sub-Saharan Africa. This work uses Integrative Systems Modeling to combine a system dynamics model of process with a statistical model of data to bring together all available sources of information.