He received his PhD in 1993 at the University of Munich, Germany. From 1993-2000, he was a Research Fellow at the Institute of Statistics at the University of Munich, also at the Institute for Epidemiology, GSF Neuherberg, and at the Institute of Medical Statistics, University of Cologne. He also works as a statistical consultant for the pharmaceutical industry. His major research interest is in the field of statistical procedures for group sequential and adaptive plans in clinical trials.