He obtained a PhD in Medical Biophysics from Indiana University and postdoctoral training in Immunology at Johns Hopkins University. Dr Shaikh's laboratory studies how mitochondrial inner membrane biophysical organization is impaired in a range of diseases including cardiac ischaemia–reperfusion injury. The laboratory is also seeking to understand mechanisms by which obesity dysregulates humoral immunity upon viral infection and testing select therapeutics for improving antibody production. Dr Shaikh is supported by several NIH and industry grants using human and rodent models.