He has served on the faculties of both the University of Washington and the University of Tennessee, and in 1992 was recruited by the prestigious Swedish Medical Center to develop a neuroscience institute. In 2002, he left active practice to become medical director for a startup med-tech company (that went public in 2006) and he now chairs the Institutional Review Board of a major medical center in the Pacific Northwest. Leveraging a love for thrillers since the early 1970s, Wyler devoted himself to fiction writing in earnest, eventually serving as vice president of the International Thriller Writers organization for several years. After publishing his first two medical thrillers Deadly Errors (2005) and Dead Head (2007), he officially retired from medicine to devote himself to writing full time.