After graduating from the University of Nebraska in 2000 with a master's degree in physiology, he completed his medical education at the University of Nebraska Medical Center. In his final year, at the University of Nebraska Medical Center, he was selected as the National Student of the Year by the Society of Dermatology Physician Assistants. Isaac is a fellow member of the Society of Dermatology Physician Assistants, the American Academy of Physician Assistants, and the Nevada Academy of Physician Assistants