His cross-disciplinary research is community based. His research interests focus on Health Virtual Communities, Mobile Communities, e-collaboration, particularly in the domain of Chronic Disease Management and health promotion: Peripheral Arterial Disease, Kidney Diseases and Mental Health. He also has research interests in Hospital Patient Services and Patient Quality of Care (e.g. readmission patterns, radiation dose reduction), and Picture Archiving and Communication Systems (PACS). He has published books, chapters, and articles in these areas. Christo particularly enjoys working in applied research in partnerships with IT industry, he received funds from the Ontario Center of Excellence - Voucher for Innovation Program (OCE - VIP) and the Canadian Institute for Health Research - eHealth Innovations Partnership Program (CIHR-eHIPP).