halides are readily prepared from the corresponding secondary alcohols through the conventional means using bromine phosphorous tribromide thionyl chloride etc as a halogenating agent the preparation of the grignard 39 s reagent or the lithium compound is well known to the art the inert solvent may be ethers such as ethyl ether and tetrahydrofuran aromatic hydrocarbons such as benzene toluene and xylene and a mixture thereof it is preferable to employ 1 to 5 mols of the organometallic compound per one mol of the compound i after the reaction water or an aqueous solution of ammonium chloride is added with cooling to the reaction mixture for hydrolysis the organic solvent layer containing the resultant product of the formula iii 1 phenyl 2 amino 3 hexanol derivatives is dried with sodium sulfate and the solvent is removed by distillation to recover the product when an acid is employed for hydrolysis the resultant product of the formula iii may be further dehydrated to produce the compound of the formula iv where the compound iii of high purity is required the product is purified by silica gel chromatography alternatively highly purified crystals of the compound iii may be obtained in the form of an acid addition salt by reacting the free base form of the compound with an inorganic acid such as hydrochloric acid or sulfuric acid or organic acid such as oxalic acid tartaric acid or citric acid some of the new 1 phenyl 2 amino 3 hexanol derivatives have an activity of female sex.