in a capillary with a diameter of less than 1 mm or a fine groove with a width of less than 100 u03bcm on a substrate the fine groove may be connected to form a continuous flow channel in the present invention the monolithic reactive porous support has the reactive sites on the surface of the backbone and the pores with a diameter of 100 nm or greater a plurality of the monolithic reactive porous supports can be combined to use as a system device for example a multi dimensional liquid chromatography system according to the present invention it is possible to obtain the reactive porous support having the reactive sites on the surface thereof and the continuous open pores the supports formed in a column shape can be combined for multiple reactions first formamide a polar solvent was uniformly dissolved in 1 mol nitric acid aqueous solution with a molar ratio of formamide methanol water 1 3 5 a mixture of tetramethoxysilane and vinyltrimethoxysilane in a molar ratio of 2 8 was added to the solution to perform the hydrolysis reaction after stirring the solution for 5 minutes the resultant solution was gelled in a closed container at a temperature of 40 u00b0 c to obtain a gel.