be converted to ctp a rate limiting factor in pc biosynthesis wurtman et al biochemical pharmacology 60 989 992 2000 useful uridine containing compounds include without limitation any compound comprising uridine utp udp or ump a preferred uridine containing compound is triacetyl uridine uridine and uridine containing compounds and analogs are well tolerated in humans creatine and creatine containing compounds provide useful therapies because these compounds by virtue of increasing brain phospholipid levels can raise the levels of atp creatine and creatine containing compounds are known to be well tolerated at relatively high doses in humans conventional pharmaceutical practice is employed to provide suitable formulations or compositions for administration to patients oral administration is preferred but any other appropriate route of administration may be employed for example parenteral intravenous subcutaneous intramuscular intracranial intraorbital ophthalmic intraventricular intracapsular intraspinal intracistemal intraperitoneal intranasal or aerosol administration therapeutic formulations may be in the form of liquid solutions or suspensions as for example for intravenous administration for oral administration formulations may be in the form of liquids tablets or capsules and for intranasal formulations in the form of powders nasal drops or aerosols methods well known in the art for making formulations are described for example in u201c remington the science and practice of pharmacy u201d 20th ed ed a r.