the procedure of example 3 was repeated using 3 ethoxypropylamine in place of 2 methoxyethylamine n 3 ethoxypropyl 2 3 dimethyl 2 isopropylbutyramide 6 99 gc purity was obtained in almost quantitative yield the crude product was recrystallized from acetone water mixture m p 30 u00b0 c the procedure of example 3 was repeated using 3 isopropoxypropylamine in place of 2 methoxyethylamine n 3 isopropoxypropyl 2 3 dimethyl 2 isopropylbutyramide 7 99 gc purity was obtained in almost quantitative yield the product was further recrysallized from acetone water mixture m p 32 u00b0 c the procedure of example 3 was repeated using 3 butoxypropylamine in place of 2 methoxyethylamine n 3 butoxypropyl 2 3 dimethyl 2 isopropylbutyramide 8 99 gc purity was obtained in almost quantitative yield the product was further purified by recrystallization from acetone water mixture m p 40 u00b0 c the following testing procedure is aimed at determining physiological cooling ability of testing compounds with regard to ws 23 n 2 3 dimethyl 2 isopropylbutyramide the tests are carried out on a selected panel of 5 people the present test procedure is done on a statistical basis because sensitivity to cooling compounds will vary not only from compound to compound and from one part of.