of example oximeters and other blood chemistry sensors are well known similarly lung capacity and tidal volume of the patient may be sensed environmental parameters such as temperature pressure and humidity are in common use other sensors may be utilized as desired to be considered in the treatment profile directed to the patient such profile may include such parameters as simply the total effort to generate no during the treatment u2014 setting the sparks energy level and allowing the inhaler to run for a prescribed period of time while such operation is considered the advantages of the supplied logic provide better options in the embodiments where a spark intensity sensor is provided the actual production of no may be closely monitored and the spark intensity is closely correlated to the amount of no produced treatment profiles which consider static parameters of the patient such as age sex weight specific disease other known conditions and the like may be provided monitoring of dynamic parameters such as blood chemistry pulmonary function motion and the like may be done and treatment profiles may be selected or adjusted to accommodate such changing conditions time dependent profiles such as providing no at intervals or varying the amount of no administered may over time may also be dictated by the treatment profiles profiles may be adjusted according to past history of prior treatment profiles may be set by the manufacturer set according to a patient specific prescription or a combination between the two options where the inhaler is pre programmed and adjustments to the program are created to provide best fit to each patient needs in.