mg of coenzyme q10 u201c ubiquinone u201d and seek emergency medical treatment although the physician must be aware of the possibility of myopathy when treating any patient with a statin for any reason it bears emphasizing that this occurrence is exceedingly rare and that expected interferon side effects are almost always the correct explanation for mild muscle and joint complaints under no circumstances should the patient make this determination should you initiate this plan the presence or absence of myopathy will then be documented and treated appropriately if myopathy is not present upon specific testing the regimen may be resumed immediately if the patient has not taken lovastatin for more than 48 hrs treatment should resume with 40 mg and return to the full target dose of 60 mg under your direction over a period of four days 9 if surgical treatment is anticipated or the patient withstands significant injury or inflammation protocol modification may be necessary the recommended change consists of cessation of lovastatin beginning one day before surgery until three days after surgery dosage may then resume at 40 mg and gradually increase back to the full target dosage over a period of two weeks if impaired wound healing is evident further cessation may be warranted.