ejaculation both of which are neurally governed the first stage erection has been thought to be mediated by the parasympathetic nervous system whose activity may be inhibited by alpha adrenergic tone cholinergic impulses from the spinal cord cause arterial dilatation and venous constriction in the penis the arterial blood in the erectile tissue of the penis builds up under high pressure due to the venous constriction which blocks the outflow of blood from the penis the second stage ejaculation is thought to be mediated by the sympathetic nervous system sensory nerves in the penis respond to sexual stimulation by sending sensory impulses to the spinal cord after processing these impulses the spinal cord sends sympathetic impulses to the male reproductive organs these sympathetic impulses stimulate alpha 1 adrenergic receptors in these reproductive organs causing them to contract this contraction results in the filling of the internal urethra with sperm and prostatic fluid the corresponding pressure increase in the internal urethra stimulates pressure receptors which send impulses to the spinal cord cholinergic impulses are then sent from the spinal cord to the penis where the skeletal muscle surrounding the erectile tissue is stimulated to contract causing ejaculation of the sperm from the internal urethra the method and compositions described herein is a system of enteral drug therapy to correct impotence in patients having no demonstrable organic cause for the disorder the method employs antihypertensive drugs of the same type often used in normotensive states wherein they have little or no effect.