octafluorocyclobutane freon 114 cryofluorane etc procedure dissolve compound a in the alcohol and isopropylmyristate add sufficient halogenated propellant and introduce into conventional aerosol containers either by pressure or by cold filing apply to affected area procedure heat the petrolatum to 60 u00b0 c add compound a and stir until thoroughly dispersed cool to room temperature apply to affected area sodium hydride 0 40 g 10 mm 60 in mineral oil was washed twice with hexane under nitrogen the sodium hydride was suspended in 15 ml of benzene and 5 hydroxy 2 3 dihydrobenzofuran 1 00 g 7 37 mm was added in 20 ml of benzene in one portion the suspension was stirred at room temperature for 1 5 hours giving a pale blue suspension cinnamyl bromide freshly distilled b p 76 u00b0 8 u00b0 at 0 2 torr 1 58 g 8 0 mm was added in 15 ml of benzene the reaction was then heated to reflux for 3 5 hours after cooling the reaction mixture was poured into 1n aqueous hydrochloric acid partitioned and back extracted with ether the combined organic layers were dried over magnesium sulfate filtered and stripped to a brown oil the crude reaction product was flash chromatographed with 600 ml of 20 ethyl acetate in hexane on a 30 mm by 6 34 column of silica gel this chromatography gave.