
{"publication_number": "US-2005261364-A1", "abstract": "compositions comprising bis - tetrahydrofuran benzodioxyolyl sulfonamide compounds that are surprisingly effective protease inhibitors and a second antiretroviral compound are disclosed . methods of inhibiting retrovirus proteases , in particular multi - drug resistant retrovirus proteases , methods of treating or preventing infection or disease associated with retrovirus infection in a mammal , and methods of inhibiting viral replication are also disclosed .", "application_number": "US-60634203-A", "description": "in order that the invention herein described may be more fully understood , the following detailed description is set forth . and n - oxides , salts , esters , stereoisomeric forms , racemic mixtures , prodrugs and metabolites thereof . the molecular structure depicted above is named hexahydrofuro [ 2 , 3 - b ] furan - 3 - yl - n -{ 3 -[( 1 , 3 - benzodioxol - 5 - ylsufonyl )( isobutyl ) amino ]- 1 - benzyl - 2 - hydroxypropyl 