hydroxyapatite resorbs very slowly over a period of years tricalcium phosphate resorbs slowly in about 3 6 months calcium sulfate resorbs more quickly in less than 3 months as shown in fig1 the tendency for the dbm to flow with the carrier is particularly noticeable when the mixture is delivered and packed into the mesh container 10 the dbm particles flow through the mesh pores under the force applied by the emptying of the filled tube into the confined mesh container the smaller of the dbm particles flow through the mesh pores into the bony defect these dbm particles are the sole osteoinductive elements in the mixture as the dbm is forced through the mesh pores the dbm makes intimate contact with the irregular surfaces of the bony defect and consequently causes new bone to grow precisely at the surfaces where bony fusion is intended the mesh pores generally about 250 5000 microns may act as a sieve or filter that preferentially retains the non demineralized granules this filtering feature may allow the larger irregularly shaped granules to pack tightly together within the mesh while the fluid component also carrying the particles of dbm may fill the interstices of the packed granules and flow through the pores of the mesh the relationship between the sizes of the dbm the mesh pores and the granules may generally be described as follows if the granules have a size equal to x then the dbm size may generally be in the range of 0 3 0 7x and the pore size may generally be in the range of 0 5 2 5x the formulation of the mixture may generally be in the range of.