a demethylated dna product in the presence or absence of a test agent d analyzing the extent of demethylation and d comparing the extents of the demethylation in the presence and absence of the test agent and thereby identify the test agent as a modulator of the dna demethylation activity of the dna methyltransferase application_number US 201314647816 A description the present invention is more particularly described in the following examples that are intended as illustrative only since numerous modifications and variations therein will be apparent to those skilled in the art various embodiments of the invention are now described in detail referring to the drawings like numbers indicate like components throughout the views as used in the description herein and throughout the claims that follow the meaning of u201c a u201d u201c an u201d and u201c the u201d includes plural reference unless the context clearly dictates otherwise also as used in the description herein and throughout the claims that follow the meaning of u201c in u201d includes u201c in u201d and u201c on u201d unless the context clearly dictates otherwise moreover titles or subtitles may he used in the specification for the convenience of a reader which shall have no influence on the scope of the present invention additionally some terms used in this specification are.