trpv1 receptor and can be used for the preparation of pharmaceutical compositions for the treatment of inflammatory states such as chronic pain and inflammatory hyperalgesia these formulations can be prepared by conventional methods and excipients such as those disclosed in remington 39 s pharmaceutical sciences handbook xvii ed mack pub n y u s a the invention will be hereinafter illustrated by means of the following examples and schemes 1 and 2 the examples are provided only for the purpose of illustrating the invention and are not to be deemed as limiting the invention in any manner the reactions were routinely monitored by thin layer chromatography tlc on silica gel precoated f 245 merck plates and the products visualized with an iodine or potassium permanganate solution 1 h nmr spectra were recorded in cdcl 3 cf 3 cood or dmso d 6 with a bruker ac 200 spectrometer peak positions are given in parts per million u03b4 downfield from tetramethylsilane as internal standard and j values are given in hz ir spectra were recorded on a pye unicam sp 300 spectrometer using the kbr wafer technique mass spectra were obtained with a shimadzu qp5050 di 50 spectrometer the expression u201c light petroleum ether u201d refers to petroleum fraction boiling at 40 60 u00b0 c melting points m p were determined on a buchi tottoli instrument and are uncorrected chromatographies were performed using merck 60 200 mesh silica gel the synthesized compounds showed 1 h nmr spectra in agreement with the.