4h 7 6 doublet j 14 hz 1h a solution of 374 g 2 03 moles of 4 fluorocinnamoyl chloride in 2 l of dioxane was added drop by drop at 20 u00b0 c to a solution of 297 g 4 87 moles of ethanolamine in 2 l of dioxane the reaction medium was stirred for 3 hours at room temperature left overnight and concentrated under low pressure the residue was taken up by a sodium bicarbonate solution the precipitate of n 2 hydroxyethyl 4 fluorocinnamamide was filtered washed with water and dried yield 351 g or 83 of theory the product was purified by recrystallization in ethylacetate melting point 100 u00b0 102 u00b0 c ______________________________________percentage analysis c sub 11 h sub 12 fno sub 2 m 209 22 c h f n ______________________________________calculated 63 14 5 78 9 08 6 70found 6309 5 68 9 32 6 72______________________________________ a mixture of 9 5 g 0 05 mole of 4 acetylcinnamic acid obtained according to g h cleland j org chem 34 744 1969 of 30 g of thionyl chloride and 40 cc of benzene was brought to reflux for 20 minutes the solution was concentrated dry under low pressure the residual solid was dissolved in 100 cc of dioxane and the resulting solution was added dropy by drop at a temperature of 20 u00b0 c to a solution of 9 3 g 0 15 mole of ethanolamine in 50 cc of dioxane the mixture was stirred for 1 hour at room temperature poured into a mixture of 500 g of ice and 20 cc of 10n hydrochloric acid then.