to give the title compound cmr dmso d 6 u03b4 167 6 153 9 136 4 127 1 121 5 119 6 114 1 107 5 51 9 31 3 and 26 5 concentrated hydrochloric acid 425 ml is added to a slurry of 5r methylamino 5 6 dihydro 4h imidazo 4 5 1 ij quinolin 2 1h one maleate vii example 9 850 g in ethanol 7 65 liters the mixture is stirred at 20 25 u00b0 and concentrated while adding additional ethanol the product is isolated by filtration and the cake is washed with ethanol and dried to give the title compound u03b1 25 d u2212 35 u00b0 water uv 206 59400 227 7020 279 5540 282 5570 nmr 400 mhz d 2 o u03b4 7 05 7 09 6 95 6 99 4 73 4 09 4 13 3 96 4 01 3 88 3 93 2 94 3 25 and 2 76 cmr 100 mhz d 2 o u03b4 155 25 126 26 126 08 123 08 120 88 114 27 108 97 52 60 39 72 31 49 and 26 34 a solution of 5r 5 methylamino 5 6 dihydro 4h imidazo 4 5 1 ij quinoline 2 1h one hydrochloride viii example 10 11 0 kg and phosphorous pentasulfide 20 4 kg in pyridine is refluxed until the reaction is complete the reaction is quenched with aqueous potassium hydroxide the solution is vacuum distilled and diluted with water concentrated hydrochloric acid is added to lower the ph to 10 0 10 5 and the solution is extracted with a mixture of n butyl alcohol ethyl acetate 20.