publication_number US 2011137318 A1 abstract a method for filling a bone defect in a subject in need thereof is disclosed the method includes heating a bone cement composition at a first temperature where the bone cement composition is fluidic and delivering an effective amount of the fluidic bone cement composition at a second temperature to the bone defect thereby filling the bone defect and allowing the fluidic bone cement composition to solidify the second temperature being sufficiently high for maintaining the bone cement composition fluidic without causing thermal necrosis also disclosed are systems for carrying out the method application_number US 63007809 A description this invention relates to a method for repairing a bone defect in a subject in need thereof by injecting a molten bone cement composition into the defect thereby filling it upon solidification of the composition preferably the composition includes a thermoplastic biocompatible polymer such as plga and optionally a biocompatible salt containing calcium such as calcium phosphate e g beta tricalcium phosphate or calcium sulfate the bone cement composition can be prepared via conventional method in one embodiment the composition is prepared by mixing plga and tricalcium phosphate tcp more specifically plga is first dissolved in dichloromethane dcm to afford a viscous solution 30 w v next tcp and nacl are added into the solution the resulting mixture is stirred to form a homogeneous solution the solvent is then removed to form a dried mixture which is then rinsed with deionized water to remove water.