in this case the antibiotics are discharged through conduit 9 while the entrainer is conveyed to reservoir 13 through conduit 15 in most cases the antibiotics have sufficient purity and are merely dried further and sterilized from the separator 8 the antibiotic free extraction agent is returned to pump 10 which compresses it and conveys it to heat exchanger 11 where it is brought to the extraction tempeature the extraction agent is then conveyed into the base of high pressure column 4 extraction agent losses are replenished from reservoir tank 12 the entrainers to be added to the extraction agent are obtained from reservoir tank 13 the extraction residue is taken from high pressure column 4 through conduit 16 this is the extracted solution free of antibiotics or poor in antibiotics which may still contain remainders of entrainer several antibiotics have been isolated in pure form according to the process of the present invention from different compositions of antibiotic containing solutions an unpurified solution containing 72 2 ethanol 23 8 water and 4 penicillin v acid phenoxyethyl penicillin acid and small quantities of impurities which could only be detected by a hplc peak is continuously extracted with carbon dioxide at.