can be potential product for perfume industry alkylation reaction can be done using stork enamine conditions to substitute the macrocycles with different alkyl groups see fig1 macrocycles with potential melanin production inhibition activity which can be used in skin care products u201c melanin production inhibitors u201d n d diethyl 9 octadecenedioate product from invention embodiment 1 can undergo acyloin condensation to give 2 hydroxy macrocyclic ketones which can inhibit melanin production as shown in fig1 civetone can be reduced to give product c which is a potential melanin production inhibitor and hydrogenation of product c gives civetol d alamu o j waheed m a amp jekayinfa s o 2008 effect of ethanol palm kernel oil ratio on alkali catalyzed biodiesel yield fuel 87 8 9 1529 1533 doi 10 1016 j fue1 2007 08 011 burdett k a harris l d margl p maughon b r mokhtar zadeh t saucier p c amp wasserman e p 2004 renewable monomer feedstocks via olefin metathesis fundamental mechanistic studies of methyl oleate ethenolysis with the first generation grubbs catalyst organometallics 23 9 2027 2047 doi 10 1021 om0341799 choo y may ooi k e amp ooi i hong 1994 synthesis of civetone from palm oil products 71 8 911 913 dinger m b amp mol j c 2002 high turnover numbers.