
{"publication_number": "US-9328088-B2", "abstract": "the present invention relates to organic compounds , usable as ligands in the preparation of lanthanide complexes or of certain water - soluble transition metals , a method for preparation thereof , and the use of said organic compounds as fluorescent probes .", "application_number": "US-201214345705-A", "description": "the present invention is illustrated by the following examples , to which it is not , however , limited . a compound of formula ( i - 1 ) was synthesized according to the following reaction scheme : to a solution of compound 5 ( prepared according to the reference p . kadjane et al ., inorg . chem ., 2009 , 48 , 4601 - 4603 ) ( 267 . 6 mg , 0 . 562 mmol ) in anhydrous acetonitrile ( 10 ml ) were added 270 . 5 mg of glyphosate derivate of formula nh [ po ( oet ) 2 ( cooet )] ( prepared according to the reference s . aime et al ., chem . eur . j . 2006 , 6 , 2609 - 2617 ) ( 1 . 068 mmol ) and 310 . 8 mg of k 2 co 3 ( 2 . 249 mmol ). the resulting solution was heated with stirring at 60 \u00b0 c . for 48 hours under argon . the product was purified by column chromatography on silica using a mixture of solvents ( from 0 / 10 to 2 / 8 ( v / v ) meoh / ch 2 cl 2 ). the expected compound 6 was obtained in the form of a white solid in a yield of 59 %. 1 h nmr ( 300 mhz , cdcl 3 ) \u03b4 ( ppm ): 8 . 37 ( d , j = 2 . 6 hz , 2h ); 7 . 87 ( s , 2h ); 6 . 47 ( d , j = 2 . 6 hz , 2h ); 4 . 02 - 4 . 18 ( m , 12h ); 3 . 99 ( s , 4h ); 3 . 58 ( s , 4h ); 3 . 18 ( s , 2h ); 3 . 14 ( s , 2h ); 1 . 14 - 1 . 32 ( m , 18h ). 31 p { 1 h 