wells each test well having a biological chip having a molecular probe array introducing samples into the test wells subjecting the biological chip plate to manipulation by a fluid handling device that automatically performs steps to carry out reactions between target molecules in the samples and probes and subjecting the biological chip plate to a biological chip plate reader that interrogates the probe arrays to detect any reactions between target molecules and probes application_number US 63005196 A description the following terms are intended to have the following general meanings as they are used herein a complementary refers to the topological compatibility or matching together of interacting surfaces of a probe molecule and its target thus the target and its probe can be described as complementary and furthermore the contact surface characteristics are complementary to each other b probe a probe is a surface immobilized molecule that can be recognized by a particular target examples of probes that can be investigated by this invention include but are not restricted to agonists and antagonists for cell membrane receptors toxins and venoms viral epitopes hormones e g opioid peptides steroids etc hormone receptors peptides enzymes enzyme substrates cofactors drugs lectins sugars oligonucleotides nucleic acids oligosaccharides proteins and monoclonal antibodies c target a molecule that.