10 days a1 fermentation mycelium powder b2 culture supernatant concentrated fluid c1 sporophore powder a2 water extract of fermentation mycelium b2 fermentation concentrated fluid c2 water extract of sporophore powder dexamethasone sodium phosphate asthma as a chronic airway inflammatory disease is characterized by significant increase of eosinophils of bronchus and lung eosinophils can release tens of inflammatory substances such as cytokines leukotriene and prostapar etc which may cause inflammation edema injury and thickening of airway make narrow airway and therefore lead to dyspnea thus eosinophil is considered as a target of screening drugs for relieving cough at present the medicine which can inhibit inflammation of airway eosinophils would probably be used for preventing and treating asthma in this test substance b fermentation concentrated fluid shows good inhibition on eosinophils of bronchus and lung of sensitized cavies after being attacked by antigen as described in table 3 3 effect of fermentation product of cryptoporus volvatus peck schear with different dose on leukocyte total number and eosinophils in bronchial lung lavage solution of sensitized cavies after being attacked by antigen 75 sd cavies are divided into 8 groups and treated with 2 egg albumin gel solution to cause allergy subcutaneous injection is given into four soles of each cavy 0 1 ml each part and the operation is repeated for one time 10 days later the cavies are administered with the medicine samples since the fourteenth day after allergy has been caused the cavies are administered by intragaster method.