confined to the clinic and conditioned with standardized meals maintaining both sodium and potassium intakes and fixed quantity of water at predetermined intervals during the equilibration periods urine samples were collected at the end of equilibrium period days 5 6 and days 13 14 and on dosing days days 7 and 15 for timed intervals of 0 1 1 2 2 4 4 6 6 8 8 12 12 16 16 24 the urine samples collected during the be study were tested for potassium and creatinine concentrations using validated bioanalytical methods even though the tablets of example 10 were bioequivalent to k dur 20 the tablets were not considered to be generically equivalent to k dur 20 because the tablets of example 10 failed to disperse in water within 2 minutes as required for k dur u00ae see physicians 39 desk reference page 3047 of pdr edition 57 2003 microcapsules of kcl crystals batch size 400 kg were coated to achieve a weight gain of 2 with an aqueous dispersion of ethylcellulose commercially available as aquacoat ecd30 latex dispersion from fmc philadelphia pa and diethyl phthalate at a ratio of 76 24 in a fluid bed coater a compression blend comprising 85 5 parts of compressible coated microcaps kcl 11 9 parts of ceolus 2 0 part of crospovidone 0 3 part of colloidal silicon dioxide and 0 3 part of sodium lauryl sulfate were compressed into 20 meq er tablets the capsule shaped monogrammed tablets u00be u2033 u00d7 u215c u2033 weighing about 2 g exhibited a mean hardness of about 19 1 kp and.