a latin square strategy and a reactor for effecting a chts method on the catalyzed chemical experimental space to produce results application_number US 94331801 A description according to the invention a set of reactant factors and their levels and a set of process factors and their levels are selected by an experimenter the levels are ordered by a latin square strategy to define an experimental space a chts method is effected by performing runs of the experimental space in a chts system the data from the runs are analyzed with graphical and statistical tools to determine a set of factor levels that provides a best result from the experimental space a determination can be made as to whether the set of factor levels is a minimal set by examination by a statistical technique such as percent of variance explained and tukey simultaneous test if the values of the best factor levels are not significant the process is reiterated either by replication with the same or a reduced number of factor levels to reduce overall error or by application of a different design such as a split plot design a latin square is a two dimensional array or matrix of symbols such that each row and each column contains each symbol exactly once a latin square matrix representing t number of factors can be generated by 1 postulating a t u00d7 t sized matrix 2 designating the factors with letters of.