hsv 1 based vectors for gene therapy of neurological diseases and brain tumours part ii vector systems and applications neoplasia 1 5 402 16 louis d n 2006 molecular pathology of malignant gliomas ann rev pathol mech dis 1 97 117 mackay j a deen d f szoka f c 2005 distribution in brain of liposomes after convection enhanced delivery modulation by particle charge particle diameter and presence of steric coating brain res 103 139 53 markert j m medlock m d rabkin s d gillespie g y todo t hunter w d palmer c a feigenbaum f tornatore c tufaro f martuzo r l 2000 conditionally replicating herpes simplex virus mutant g207 for the treatment of malignant glioma results of a phase 1 trial gene therapy 7 867 74 marmarou a takagi h shulman k 1980 in brain edema eds cervos navarro j and ferszt r raven new york 28 345 58 mastakov m y baer k kotin r m during m j 2002 recombinant adeno associated virus serotypes 2 and 5 mediated gene transfer in the mammalian brain quantitative analysis of heparin co infusion mol ther 5 4 371 380 mcmahon e j bailey s l miller s d 2006 cns dendritic cells critical participants in cns inflammation neurochem int 49 2 195 203 morrison p f laske d w bobo h oldfield e h dedrick r l 1994 high flow microinfusion tissue penetration and pharmacodynamics am j physiol 35 8292 305 neeves k b sawyer a.