cannula terminating in the outer wall of the inside cannula at a point below the top of the inside cannula the outer cannula having a port which permits entry or exit of gases and liquids and having an aperture which aligns with the opening in the wall of the sipper tube insert when the transfer probe is docked with the filter sipper tube constricted region the sipper tube insert being sized to fit within a vessel containing a septum port and the transfer probe being capable of piercing the septum port and entering the top of the sipper tube such that fluid or gas may be delivered to the environment surrounding the sipper tube insert by dispensing the fluid or gas from the inner cannula onto the top of the docking point of the sipper tube insert and the fluid or gas moves into the environment through he aperture in the wall of the sipper tube and fluids or gases may be removed from the environment surrounding the sipper tube insert by moving the beveled end of the inner cannula into the docking point of the sipper tube and withdrawing the liquid or gas through the frit and into the inner cannula the device of this invention permits fluid addition and waste or product removal from a vessel while maintaining an inert atmosphere over a range.