from a metal material such as a stainless steel a superelastic alloy a cobalt alloy a noble metal such as gold platinum or tungsten or an alloy containing such a noble metal in particular the coil 4 is preferably made from a radiopaque material such as a noble metal if the coil 4 is made from such a radiopaque material the guide wire 1 a can exhibit an x ray contrast performance this makes it possible to insert the guide wire 1 a in a living body while confirming the position of the distal end portion of the guide wire 1 a under fluoroscopy the distal side and proximal side of the coil 4 may be made from different alloys for example the distal side of the coil 4 may be formed of a coil made from a radiopaque material and the proximal side of the coil 4 be formed of a coil made from a relatively radiolucent material such as a stainless material the entire length of the coil 4 is not particularly limited but may be in a range of about 5 to 500 mm the proximal end portion and the distal end portion of the coil 4 are fixed to the first wire 2 by a fixing material 11 and a fixing material 12 respectively and an intermediate portion close to the distal end of the coil 4 is fixed to the first wire 2 by a fixing material 13 each of the fixing materials 11 12 and 13 is a solder brazing material alternatively each.