the interaction between gp iib iiia on the platelet membranes and fibrinogen adsorbed to the surface of the circuit gluszko et al amer j physiol 252 h 615 621 1987 platelets released from artificial surfaces show impaired hemostatic function compounds of the invention may be administered to prevent adhesion other applications of these compounds include prevention of platelet thrombosis thromboembolism and reocclusion during and after thrombolytic therapy and prevention of platelet thrombosis thromboembolism and reocclusion after angioplasty or coronary artery bypass procedures they may also be used to prevent myocardial infarction the dosage regimen utilizing the compounds of the present invention is selected in accordance with a variety of factors including type species age weight sex and medical condition of the patient the severity of the condition to be treated the route of adminstration the renal and hepatic function of the patient and the particular compound or salt thereof employed an ordinarilly skilled physician or veterinarian can readily determine and prescribe the effective amount of the drug required to prevent counter or arrest the progress of the condition oral dosages of the present invention when used for the indicated effects will range between about 0 01 mg per kg of body weight per day.