bis ethane sulfonate in acidic and basic aqueous media in a typical experiment 50 mg of 2 2 39 dithio bis ethane sulfonate as produced by using the above described method was dissolved in one ml of water and the ph was adjusted to 1 5 2 0 3 0 4 0 5 0 or 6 0 by adding 1n hydrochloric acid in water or the ph was adjusted to 8 0 or 9 0 by adding 1n sodium hydroxide in water the reaction mixture was stirred for 24 hours at room temperature the water was removed at reduced pressure dissolved in spectral grade d 2 o and the proton nmr spectrum was recorded one peak corresponding to the starting material was observed on the nmr spectra no additional peaks were observed the stability of 2 2 39 dithio bis ethane sulfonate at ph 1 5 was further studied by heating the reaction mixture to 100 degrees centigrade for 10 minutes no change in the proton spectrum was observed after heating the 2 2 39 dithio bis ethane sulfonate ph 1 5 the data indicate that 2 2 39 dithio bis ethane sulfonate is stable in aqueous solutions at ph values from 1 5 to 9 0 method 1 to produce a sterile solution containing cisplatin and 2 2 39 dithio bis ethane sulfonate this example is designed to detail one method to produce a sterile solution containing cisplatin and disodium 2 2 39 dithio bis ethane sulfonate for the purpose of this example cisplatin and cis diammine dichloro platinum are used interchangeably for.