the fish gelatin water insoluble the insoluble particles can then be removed or collected from aqueous solution by conventional techniques such as ultracentrifugation or filtration or the like these harvested particles can be collected for conventional oral dosage forms examples of the product of this invention follow in all instances fish gelatin solution was obtained from norlund products inc new brunswick n j fish gelatin contained 45 solids in solution a fish gelatin solution containing 6 grams of fish gelatin at a 45 solids ratio was diluted with 54 mls of water and was mixed together with 56 ml aliquot of 20 of sodium sulfate which was added drop wise to the stirred solution over approximately 10 minutes after stirring for approximately 1 2 hour 1 ml of 5 v v glutaraldehyde was added after 31 2 minutes 60 mls of a 12 weight by weight solution of sodium metabisulfite was added to reduce the glutaradehyde to an alcohol to prevent further reaction the hardened soluble particles have a variety of size ranges with many below the 1 micron range particles below the micron range were not successfully harvested by filtration through a nylon 66 filter with a pore size of 0 45u the filter was however useful in sorting the larger particles it should be noted that particles of all sizes were prepared with sodium sulfate and then successfully harvested by lyophilization in addition particles in the 100 nm range have been harvested by ultracentrifugation after first sorting the larger particles.