benefit the patient table xii______________________________________immunomodulating effect of npt 16416 enhancement of e rosettes active e rosettes active compound conc m x increase______________________________________control 37 npt 16416 5 u00d7 10 sup 10 42 7 6npt 16416 5 u00d7 10 sup 9 58 5 34npt 16416 5 u00d7 10 sup 8 62 5 36 5npt 16416 5 u00d7 10 sup 7 55 5 23npt 16416 5 u00d7 10 sup 5 43 10______________________________________ the subject compounds of this invention have been shown to inhibit the replication of a representative sample of both an rna influenza and a dna virus herpes virus using standard tissue culture techniques in the case of the rna virus a 48 to 78 inhibition of influenza virus growth was demonstrated in vitro table vi over a concentration range of 0 05 150 u03bcg ml and in the case of the dna virus a 33 to 65 inhibition was noted from 37 5 150 u03bcg ml other members of the rna and dna class of viruses are shown in table a above and are responsible for the diseases specified in addition a number of viruses have been isolated which cause tumors and thus antiviral agents may have antitumor properties it is an established fact that many infectious agents such as viruses influenza virus hsv friend leukemia virus bacteria and fungi cause an immune suppressed state in the host weakening his defenses to infection by infectious agents most other antiviral antimetabolite substances like arac cause a suppresion of host immune.