also excluded the panelists appear to be in normal health and do not have signs of acute or chronic disease including dermatologic problems upon examination at the site of testing the participating panelists are examined to determine that they are devoid of excessive warts nevi moles sunburn suntan scars or active dermal lesions finally the panelists do not use systemic or topical retinoids antihistamines or similar agents during the course of the study and two weeks prior to the commencement of the study distinct areas of about 4 cm 2 are marked on the backs of each of the panelists each for applying the two samples i e lotion with 2 kojic acid and the lotion with 1 saccharomyces cerevisiae enzyme extract of the present invention an additional area is marked as the untreated irradiated control each panelist receives twice the med of uv b on each site area the sites are radiated with a xenon arc solar simulator 150 watt with filters mm ug 5 to expose the skin to uv b and uv a radiation tanning is observed for 5 days after irradiation at which point baseline color measurements are made using a minolta chromameter which measures the difference in reflectance of the skin l the change in the value of the difference in reflectance is u03b4l the delta values are measured against a baseline.