52 of 18i as an orange solid mp 144 7 146 1 u00b0 c 1 h nmr 300 mhz cdcl 3 u03b4 8 03 s 1h 8 00 dd j 8 25 hz j 2 1 hz 1h 7 82 m 1h 7 27 7 11 m 4h 6 92 m 2h 6 79 m 2h anal calcd for c 24 h 20 fn 3 o 5 s c 59 87 h 4 19 n 8 73 found c 59 59 h 4 27 n 8 48 2 pyridin 3 yl oxymethyl pyrrolidine 1 carboxylic acid tert butyl ester 19 was prepared according to the same procedure for compound 9 except using 3 hydroxypyridine the crude product was purified with ether to afford 1 70 g 61 of 19 as a colorless oil 1 h nmr 300 mhz cdcl 3 u03b4 8 32 s 1h 8 21 s 1h 7 21 m 2h 4 16 m 2h 3 99 3 86 m 1h 3 38 m 2h 2 05 1 84 m 4h 1 47 s 9h 5 2 pyridin 3 yl oxymethyl pyrrolidine 1 sulfonyl 1h indole 2 3 dione 20 was prepared according to the same procedure for compound 10 except using compound 19 and the crude product was recrystallized from ethyl.