been diagnosed as having it inhibiting the disease disorder or condition e g impeding its progress and relieving the disease disorder or condition e g causing regression of the disease disorder and or condition treating the disease or condition includes ameliorating at least one symptom of the particular disease or condition even if the underlying pathophysiology is not affected such as treating the neurological condition such as moderate to severe pain of a subject by administration of an agent even though such agent does not treat the cause of the condition the term u201c treating u201d u201c treat u201d or u201c treatment u201d as used herein includes curative preventative e g prophylactic adjunct and palliative treatment the phrase u201c therapeutically effective amount u201d is an art recognized term in certain embodiments the term refers to an amount of a salt or composition disclosed herein that produces some desired effect at a reasonable benefit risk ratio applicable to any medical treatment in certain embodiments the term refers to that amount necessary or sufficient to eliminate or reduce medical symptoms for a period of time the effective amount may vary depending on such factors as the disease or condition being treated the particular targeted constructs being administered the size of the subject or the severity of the disease or condition one of ordinary skill in the art may empirically determine the effective amount of a particular composition without necessitating undue experimentation in certain embodiments the pharmaceutical compositions described herein are formulated in a manner such that said compositions will be delivered to a patient in a therapeutically effective amount.