the solution is stirred until all the powder is wetted the heated solution is then placed in an ice bath and cooled until the methyl cellulose is fully hydrated or about 45 minutes to slightly less than 80 ml of water each ingredient is added until dissolved methylcellulose solution is added to the solution containing the other ingredients while stirring the solution is brought to 200 ml using distilled water ______________________________________each amountcontains ingredients per batch______________________________________0 84 or 8 4 phenylephrine oxazolidine 1 18 or 16 8 gm1 or 10 phenylephrine hcl 2 or 20 gm0 01 pluronic p 103 0 02 gm0 05 methylparaben 0 10 gm0 01 propylparaben 0 02 gm0 25 chlorabutanol 0 5 gmq s sesame oil 200 gm______________________________________ equivalent molar concentrations because of the instability of the prodrug aqueous solution an oil suspension was prepared the parabens and chlorobutanol are dissolved in about 105 gms of sesame oil the oil may be heated to about 50 u00b0 c to facilitate the dissolution of each ingredient the pluronic p103 is incorporated into the drug powder using a motar and pestle the remaining sesame oil is added to the wetted drug powder and triturated until an acceptable slurry is formed the sesame oil containing the preservatives is added to the slurry to form the suspension butylated hydroxytolunene 0 03 butylated hydroxyanisole 0 02 or.