volume but not in excess of 10 volume volume a sensor strip 422 composed of solid base member 420 chemical entity 430 binding agent layer 440 and packaging layer is present in the container 485 when sample 480 is added the packaging layer 450 dissolves bottom fig4 to allow for binding of analyte 457 bound analyte bound analyte 457 leads to increased charge concentration fig1 right that catalyzes increased degradation of hydrogen peroxide to water and oxygen oxygen is detected by po 2 electrode 496 the oxygen electrode 496 may be in sample 480 as shown in fig4 or it may alternatively measure po 2 in the vapor 491 immediately above sample 480 not shown increase in po 2 signals analyte presence and its interaction with bound binding agent layer 440 reference is now made to fig5 which is a schematic of an alternative embodiment of a sensor detection system 500 that is constructed and operative in accordance with a preferred embodiment of the invention container 585 holds sample 580 that contains un bound analyte top 555 and buffered hydrogen peroxide h 2 o 2 not shown at a concentration of greater than 0 001 volume volume but not in excess of 10 volume volume a sensor strip 522 composed of wafer silicon 520 optional chemical entity 530 binding agent layer 540 and packaging layer is present in the container 585 when sample 580 is added the packaging layer 550 dissolves bottom fig5.