mixture of ethyl acetate 75 and hexane 25 as the eluent the fractions containing the pure product as determined by silica gel tlc were combined and the solvents removed to obtain the title b compound as an off white glassy solid 47 00 g elemental analysis calc 39 d c 22 h 26 i 3 n 3 o 10 c 30 38 h 3 03 i 43 38 n 4 79 found c 30 85 h 2 93 i 43 77 n 4 75 to a stirred solution of the title b compound 8 73 g 10 mmol in n n dimethylacetamide 30 ml was added in drops the title a compound 1 8 g 13 mmol at 0 u00b0 5 u00b0 after the addition the mixture was stirred at 0 u00b0 5 u00b0 for 0 5 hours then at room temperature for 20 hours nitrogen gas was purged through the solution for 0 25 hours and the dma was removed in vacuo the residue was dissolved in ethyl acetate 200 ml and the solution was washed successively with cold aq sodium bicarbonate 2 u00d7 50 ml water 2 u00d7 50 ml and saturated sodium chloride 2 u00d7 50 ml after drying over sodium sulfate the solvent was removed in vacuo to obtain the crude furanilide as an off white foamy material 9 27 g.