3 antibodies to il 8 specifically neutralizes il 8 in psoriatic lesions not anything else to produce a more effective cream other neutralizing agents may be introduced into the topical composition the neutralizing agent may be a il 8 receptor blocking agent for example a peptide that binds to il 8 receptor site or antibodies to il 8 receptor il 8r or soluble il 8 receptors although the invention has been described with preferred embodiments it is to be understood that modifications may be resorted to as will be apparent to those skilled in the art such modifications and variations are to be considered within the purview and scope of the present invention 1 krueger g g and m duvic 1994 epidemiology of psoriasis clinical issues j invest dermatol 102 14s 18s 3 boehncke w h et al 1996 pulling the trigger on psoriasis nature 379 777 4 bruch gernarz d et al 1996 a proinflammatory activity of interleukin 8 in human skin expression of the inducible nitric oxide syntase in psoriatic lesion and cultured keratinocytes j exp med 184 2007 2012 5 baggrolin m et al 1994 interleukin 8 and related chemotactic cytokines cxc and c chemokines advances in immunology academic press inc 55 97 179 6 guzzo c 1997 the recent advances in the treatment of psoriasis advances in clincal research 15 59 68 7 kemeny l et al 1994 role of interleukin 8 receptor in skin int arch allergy immunol 104 317 322 8 gillitzer r et.