u00bc inch are used the density differential produces a clear vertical separation of micelles greater than 10 microns in diameter if a second aqueous solution is carefully added to the top of the first larger micelles will rise through it while microscopic micelles between 1 and 10 microns remain suspended in the original solution and may be extracted therefrom larger micelles containing materials which are more dense than oil will float in a layer containing smaller oil filled micelles vertical separation can thus be used to distinguish micelles by the density of the contents thereof once a layer has been selectively extracted the micelles can be separated by size exclusion glycoproteins may be altered in vivo by physical and chemical processes care must be taken to obtain fresh samples that have not been subjected to enzymatic degradation or lysis for example glycoproteins from the whites of fertilized hen eggs or juices of bruised fruits often fail to form lipo glycoprotein membranes micelles made with egg white as the source of glycoprotein when repeatedly passed through small pores adhere to each other in aqueous solution this phenomenon makes it possible to remove certain glycans mechanically during filtration glycoproteins stored on the surfaces of oil filled micelles can often be dried and then.