sub 3 oh oh ch sub 3 c sub 6 h sub 4 ch sub 2 sub 8 ch sub 3 p 12 ch sub 3 ch sub 3 oh oh ch sub 3 ch sub 2 sub 12 ch sub 3 13 ch sub 3 ch sub 3 oh oh ch sub 3 ch sub 2 sub 7 chch ch sub 2 sub 7 ch sub 3__________________________________________________________________________ in a manner similar to that described in example 5 0 021 millimole of 1 4 5 dihydroxy n 2 p n decanoylamino benzoylornithine echinocandin b is suspended in 2 0 ml of dichloromethane and to it is added 0 10 ml 1 3 mmol of trifluoroacetic acid to the resulting homogeneous reaction mixture is added in one portion 14 mg 0 22 mmol of sodium cyanoborohydride after stirring at room temperature for 2 hours a small amount of methanol is added and the votaliles removed in vacuo the residue is purified by hplc 34 zorbax 34 using water acetonitrile 50 50 fractions which contain the bulk of the product as determined by uv absorption at 268 nm are combined and lyophilized to obtain the desired 1 4 hydroxy n 2 p n decanoylamino.