product as an off white solid in 78 9 yield 3 32 g mp 38 40 u00b0 c ir kbr 2956 1749 1637 1607 1500 1484 1378 1266 1236 1159 1059 1024 953 912 853 811 cm u2212 1 1 h nmr cdcl 3 u2202 1 23 t j 7 2 hz 3h 3 87 s 2h 3 91 s 3h 4 19 m 2h 4 63 s 2h 7 11 s 1h 7 15 d j 2 7 hz 1h 7 40 dd j 1 8 8 4 hz 1h 7 68 s 1h 7 71 d j 4 5 hz 2h fabms nba m z 302 m rat paw edema and hydrolysis data are provided data are provided in tables 1 and 3 in reaction flask 1 nah 60 suspension in oil 0 43 g 0 011 mol was suspended under nitrogen in anhydrous dmf and 6mna 2 g 0 00926 mol was added dropwise reaction mixture was stirred for 2 hours and cannulated into another reaction flask 2 containing solution of dibromoacetone 7 9 g 0 0379 mol in dmf reaction mixture was stirred overnight u02dc 17hours and tlc was checked then deionized water was added and the product was.