with compound i in models of learning power and neuroprotection was to estimate the possible effects of these parameters since compound i inter alia displays a gaba ergic action since the epilepsy patient as a result of the repeated attacks often already suffers from a learning power deficit these experiments were carried out on animals which had been exposed to an amnesic factor and whose learning power was thus reduced to do this the animals were either repeatedly treated with electroshock or exposed to alcohol withdrawal to estimate the direct neuroprotective action a chronic reduced blood supply to the brain was produced by tying off afferent blood vessels all this damage leads to a reduction in the learning power which is to be assessed as an indicator of nerve cell damage gaba increasing antiepileptically active medicaments such as diazepam and sodium channel blockers such as phenytoin do not have any positive effects in these models and in higher doses adverse effects on the learning power can even occur learning power damage due to reduction of the blood supply to the brain in this model one of the carotid arteries of rats is tied off under anaesthesia the animals wake from the anaesthesia and then have a decreased learning power this was determined by means of the rod jumping test in this test the animals must learn to escape a slight electric shock to the foot which is announced to them beforehand by an acoustic signal by jumping onto a vertical rod suspended above the floor the learning power of the animals is measured in percent as the number of reactions caused jumping onto the rod during the acoustic signal phase untreated and sham operated animals anaesthetized and.