the end face of the orifice in this example however each projection 31 contains a longitudinal bore 34 which traverses also the flange 32 the outer face 33 of the flange is formed as a seal surface and intended for cooperation with a slide element 36 rotatably guided at the orifice 24 by means of a fine thread 39 here therefore the closure 30 for substance discharge is not to be removed from the orifice but remains as a constituent part of a slide seal described below which can be opened and closed the essential advantages with respect to one piece manufacture of the double cartridge and in particular inhibition of diffusion exist also in this variant the material components filled into the cylinders do indeed normally fill the longitudinal bores 34 in the closure up to the seal surface 33 but because of the physical separation from the projections 31 to the ring 24 or the wall sections 28 diffusion of the content is made difficult fig6 and is possible inside the ring only via the sections 25 as a variant it would be possible also first to close the cylinder side entrance of the bores 34 by a thin film or foil not shown integrally formed at the closure and thus to keep the cartridge contents away from the bores 34 during storage as discharge begins these seal films are caused to burst by the internal pressure in the cylinder and the bores are thereby freed.