phenyl ethylamine hydrochloride was refluxed for 0 75 hr under nitrogen and then the solvent was removed under reduced pressure the viscous residue was redissolved in 7 ml of absolute ethanol and evaporated again under high vacuum the pale yellow residue was redissolved in 7 ml of absolute ethanol diluted with 25 ml of ethylacetate and induced to crystallize by scratching the crystalline product was filtered off dissolved in 30 ml of water and basified with sodium hydrogen carbonate and the free amine was extracted exhaustively with ethyl acetate the solid residue obtained after removal of the solvent was dissolved in 8 ml of absolute ethanol and treated with hydrochlorine acid saturated absolute ether this yielded a colorless viscous oil as a precipitate which was centrifuged off and triturated with ether until it changed into a sticky solid this was recrystallized from 5 ml of warm ethanol diluted with 65 ml of ethylacetate the resulting n methyl n n butyl u03b2 3 4 dihydroxyphenyl ethylamine hydrochloride exhibited a melting point of 146 u00b0 to 148 u00b0 c to a solution of 35 ml of chloroform and 11 24 g 0 19 m of n methyl n n butylamine was added dropwise with agitation a solution of 35 ml of chloroform and 13 6 g 0 063 mol of 3 4 dimethoxy phenylacetyl chloride at 0 u00b0 the reaction was completed after 1 hr of heating at 50 u00b0 55 u00b0 the chloroform.