and the like were dissolved one hundred 100 milligrams each of leaves stem skins and roots of scopolia japonica nakai ephedra sinica stapf and cephalotaxus wilsoniana hayta and the like were placed into the extraction bath and the supercritical fluid extraction was then conducted under the same conditions as those of a filter paper experiment fractions according to the extraction time were extracted in the fraction collector equipped with the supercritical fluid extraction apparatus for the given time the vent valve was then closed and the extracts were again entrapped in the collection vessel the final extracts of alkaloids of scopolia japonica nakai in accordance with the present invention were separated by gas chromatography as shown in the data of fig2 also the final extracts of ephedra sinica stapf were separated by gas chromatography as shown in the data of fig3 the present invention will be further described by the following examples but should not be construed as being limited by them extraction of alkaloids hyoscyamine and scopolamine from scopolia japonica nakai using a supercritical fluid extraction technology solubility of pure supercritical carbon dioxide on hyoscyamine and scopolamine as a free base was measured as a basis experiment for the extraction efficiency of a supercritical.