example the usual recommended oral daily dose of deramciclane would be about 5 150 mg day or about 10 60 mg day or about 30 60 mg day or about 30 mg day the invention will be further clarified by the following example which is intended to be purely exemplary of the invention the effects of deramciclane were studied in a randomised placebo controlled double blind study the subjects were randomly assigned to four parallel groups to receive one tablet twice daily b i d of a placebo 5 mg 10 mg day 15 mg 30 mg day or 30 mg 60 mg day deramciclane the efficacy of deramciclane on the ability to tolerate stress was analysed by the visual analogue scale vas administration of deramciclane improved the ability to tolerate stress when measured by the vas the ability to tolerate stress was 29 54 and 43 better in patients receiving deramciclane 5 mg b i d 15 mg b i d and 30 mg b i d respectively than in patients receiving placebo the efficacy and safety of deramciclane was studied in the treatment of tension as compared to placebo a randomised plasebo controlled double blind parallel group 8 week study design was used patients were asked if they had muscular tension twitchings stiffness myoclonic jerks grinding of teeth unsteady voice or increased muscular tone or other tension feelings of tension fatigability startle response moving to tears easily trembling feelings of restlessness or inability to relax this tension was related to be not present mild moderate severe or very severe in addition patients 39 tension was also rated with the tension scale 1 6 moderate severe or very severe muscular tension was present in patients at baseline in 82 placebo 61 15 mg.