included such materials as silica alumina zirconia thoria and combinations thereof silica and alumina are preferred materials of this invention and among the aluminas gamma alumina is especially preferred in some applications glass or ceramic materials may be desirable the one characteristic common to all the core supports of this invention is their ability to be silylated with appropriate organosilanes the spacer molecules of this invention are organosilanes their function is to firmly bind the chiral molecules to the core support while holding such molecules sufficiently distant from the surface of the core support so as to permit the chiral molecule to approximate the physical and chemical properties it exhibits under homogeneous conditions such organosilanes are derived from materials whose formula may be given as uvwsi ch 2 n b which are characterized as having the ability to react with surface hydroxyl groups of the core support to form oxygen silicon bond s i e all have the ability to silylate the core supports the value of n may be from 1 to about 10 with n equal to 3 being a preferred material this chain of mediating carbon atoms performs the spacer function b is a functional group such as halogen amino or mercapto which subsequently reacts with the chiral acid leading to a covalent bond for example when b is a halogen it may react with an amino group of amino acids forming a carbon nitrogen bond when b is an amino group it may react with a carboxyl or.