system of the present invention may be used in non gravel packed wells it is particularly suited and beneficial in gravel pack completions when it is desired to isolate anticipated zone 24 b such as due to excessive water production selected isolation assembly 30 is deployed selected isolation assembly 30 is run into the interior 32 of completion assembly 14 via coiled tubing slick line wire line or other means locating device 40 is landed in the cooperative receiver 26 b positioning swellable material 38 adjacent to anticipated zone 24 b and its respective flow section 28 b within a time prescribed by the particular swellable material 38 and wellbore 12 conditions swellable material 38 expands from its initial position to a sealing position in the sealing position swellable material 38 blocks fluid flow from the exterior of completion assembly 30 into interior 32 and into internal bore 36 of isolation assembly 30 when it is desired to isolate zone 24 a through flow section 28 a a subsequent isolation assembly 30 is deployed in one embodiment the subsequent isolation assembly 30 is run into completion assembly 14 and its locating device 40 is mated with receiver connector 44 of.