having concave depressions 411 is used to generate parallel ultrasound waves the overall form and direction of the ultrasound waves depends upon the shape curvature radius density and distribution of the depressions 411 across the bottom surface 410 in the embodiment of fig6 b depressions 411 have the same shape and curvature radius and are uniformly distributed across the bottom surface 410 in alternative embodiments the shape curvature radius density and distribution of the depressions are varied across the bottom surface 410 parallel ultrasound waves are used to generate uniform distribution of micro pores on the skin surface referring to fig7 a drug delivery applicator 200 includes a cylindrically shaped hollow container 205 that has an inner wall 201 spaced apart from an outer wall 202 and a wick 270 situated in the space between inner wall 201 and outer wall 202 the container 205 is preferably made of a transparent hard plastic material and is discarded after use the wick 270 is made of a highly absorbent and hydrophilic material in one example the wick 270 is made of a high absorbency polyvinyl alcohol sponge pva manufactured by the m pact company under the tradename of clinicel u2122 other examples.