variously structured thus fig2 illustrates a discharge member 12 a similar to member 12 but having a hemispheric porous filter tip 12 d also in fig3 the discharge member 12 b has a slotted end 12 e to create a ribbon discharge of destabilized adhesive composition from the device 2 and in fig4 the discharge member 12 c has a nipple end 12 f for drop dispensing of destabilized adhesive composition fig5 shows a second embodiment of a device 30 of the invention for performing the new methods of the invention comprising syringe unit 32 a control valve 34 connected thereto by fluid line 35 a pressure source 36 connected to valve 34 by fluid line 37 and a suction source 38 connected to valve 34 by fluid line 39 advantageously valve 34 can be a foot operated type so a surgeon using the device 30 will have both hands free in to apply destabilized adhesive composition to a substrate in accordance with the invention syringe unit 32 has a pliable tubular section 40 partially defined by a proximal end bulb 42 and a distal end 44 capped with a nozzle 46 a filter disc 48 is fixed in the distal end 44 and distally defines an operation chamber 50 together with the tubular section 40 and the bulb 42 the chamber 50 encloses a quantity of particulate destabilizing agent 52 as defined herein as essential material of the invention in use the syringe unit 32 will suck a suitable amount of stabilized cyanoacrylate adhesive into the chamber from a container not shown through nozzle 46.