thereof and examining the degree of the hybridization moreover the snp analysis may be performed by a method selected from the group consisting of allele specific probe hybridization allele specific amplification sequencing 5 u2032 nuclease digestion molecular beacon assay oligonucleotide ligation assay size analysis and single stranded conformation polymorphism in the prediction method when the nucleotide at the position of the snp corresponding to the nucleotide at position 201 of seq id no 1 is determined as a a a or g a heterozygous genotype in step 2 it may be predicted that the sensitivity to bevacizumab an anticancer targeted drug is high when the nucleotide at the position of the snp corresponding to the nucleotide at position 406 of seq id no 2 is determined as t t t or c t heterozygous genotype it may be predicted that the sensitivity to at least one of bevacizumab and folfiri 5 fu leucovorin irinotecan anticancer targeted drugs is high when the nucleotide at the position of the snp corresponding to the nucleotide at position 251 of seq id no 3 is determined as c c c it may be predicted that the sensitivity to at least one of bevacizumab and folfiri 5 fu leucovorin irinotecan anticancer targeted drugs is high when the nucleotide at the position of the snp corresponding.