lotion an ointment a gel a liquid or any other topical form the concentration of tocotrienols used in the topical formulation is about 1 0 and the minimum concentration of tocotrienols in any formulation is about 0 1 volunteers of 15 years of age or older and in good general health were recruited into the study alopecia must have present for least 2 months and the areas alopecia must not have any visual evidence of new hair growth volunteers previously exposed to minoxidil were ineligible to participate in the study as were patients who have used hair restorers or systemic drugs like steroids antihypertensives cytotoxic compounds vasodilators anticonvulsant drugs u03b2 blockers spironolactone cimetidine ketoconazole estrogens or progesterons within the previous three months patients experiencing hair loss due to thyroid disease adverse drug reactions scalp or hair trauma structural hair shaft abnormalities and lichen planus were excluded from the study two parameters were chosen to evaluate the efficacy of tocotrienols and alpha tocopherol supplementation i hair count u2014 hair count served as the primary efficacy measure an area of 2 u00d7 2 cm was selected in the area of hair thinning for each patient and the two opposing corners of the square were permanently marked using a 4 cm 2 wire template to ensure that the hair in the same area was counted at each visit ii weight of hair u2014 a small tuft of hair at least 20 strands within the demarcated area was clipped horizontally twenty strands were randomly chosen and cut into 1 cm in.