c 74 10 h 8 70 n 12 15 the method followed that described in synthesis example 5 but using 3 u03b2 hydroxy 17 1h 1 2 3 triazol 1 yl androsta 5 16 diene compound 20 400 mg 1 18 mmol purification of the crude product by fcc silica gel ch 2 cl 2 etoh 30 1 gave compound 21 358 mg 90 mp 118 120 u00b0 c 1 h nmr 300 mhz cdcl 3 u03b4 1 17 3h s 18 me 1 25 3h s 19 me 5 76 1h s 16 h 5 95 1h s 4 h 7 73 1h s 5 u2032 h and 7 74 1h s 4 u2032 h analysis calculated for c 21 h 27 on 3 c 74 73 h 8 07 n 12 46 found c 74 65 h 8 11 n 12 34 this example describes the preparation of 3 u03b2 acetoxy 17 2h tetrazol 2 yl 16 formylandrosta 5 16 diene compound 22 and 3 u03b2 acetoxy 17 1h tetrazol 1 yl 16 formylandrosta 5 16 diene compound 23 the method followed that described for synthesis example 7 but using 3 u03b2 acetoxy 17 chloro 16 formylandrosta 5 16 diene compound 3 0 5 g 1 329 mmol 1h tetrazole 187 mg 1 59 mmol and li 2 co 3 287 mg 3 94 mmol gave a crude product 520 mg flash column chromatography on elution with pet ether etoac 5 1 gave firstly 3 u03b2 acetoxy 17 2h tetrazol 2 yl 16 formylandrosta 5 16 diene compound 22 92 mg 28 2 mp 170 172 u00b0 c decomp 1 h nmr 300 mhz cdcl 3 u03b41 1 3h s 18 me 1 29 3h s.