and deep anesthesia for about 270 minutes the pharmacological activity of chinoxicaine has been evaluated using the characteristics of i strength of anesthesia ii latent period and iii duration of anesthesia a study of infiltration anesthesia was conducted according to the beulbring wade method on male guinea pigs the median effective concentration ec 50 was 0 1 latent period was about 1 5 minutes the duration of deep anesthesia was i 25 minutes for the 0 1 solution ii 140 5 minutes for a 0 25 solution iii 310 8 minutes for a 0 5 solution and iv 313 8 minutes for a 1 0 solution on the basis of specific pharmacological activity data described in greater detail below chinoxicaine is preferably provided as either a 0 25 or 0 5 solution in 250 ml bottles for use in infiltration anesthesia and as a 1 0 or 2 0 solution in 5 ml ampoules for conduction and epidural anesthesia in alternative embodiments the anesthesia solution includes a 0 9 solution of sodium chloride a study of sciatic nerve conduction anesthesia in rats was conducted in accordance with the camaugis tekman method prior to injection of the anesthesia the rat motor activity was evaluated by applying a compression to the animal 39 s feet then a 0 2 ml volume of chinoxicaine solution was injected into the sciatic nerve area of the pronated lower extremity with the application of.