higher concentration of esmolol smaller volumes of infusion can be administered to patients under fluid restriction table 1 shows reduction of infusion rate based on the concentration of esmolol injection used if a practitioner desires a lower concentration of esmolol and or a preferred diluent to infuse into the patient in conjunction with esmolol dosing the practitioner may desire to dilute the compositions of the present invention suitable diluents include diluents used by practitioners skilled in the art typical examples include sodium chloride ringers 39 and dextrose solutions while the desired diluted concentration of esmolol will vary typical concentrations range from about 1 to about 25 mg ml and preferably 10 mg ml suitable routes for parenteral administration include intravenous subcutaneous intradermal intramuscular intraarticular and intrathecal the diluted concentrate is preferably administered by intravenous infusion the following example compositions and method of manufacture further illustrate the invention but should not be construed as limiting its scope the following describes the preparation of esmolol compositions of the present invention the concentration of each ingredient of the compositions are provided in tables 1 and 2 as follows in the foregoing formulations 1 6 the ph may be adjusted to a range of from 4 5 5 5 and preferably 5 0 the equipment and glassware for compounding filtering and filling are properly washed and depyrogenated the filter assembly filling tube assembly and other parts and equipment.