the invention on the one hand and compositions containing the non micronized active ingredient combined with a surfactant micronized or otherwise on the other hand gave the following results ______________________________________ 20 min 30 min 90 min ______________________________________non micronized diacerhein 60 80 non micronized surfactantnon micronized diacerhein 60 80 micronized surfactantcomposition of the invention 95 100 100 ______________________________________ it can be seen that the speed of dissolution of the active ingredient is markedly improved in the composition in accordance with the invention bioequivalence studies in 10 healthy volunteers were carried out according to a double blind design with a randomization table between hard gelatin capsules containing 50 mg doses of diacerhein in a commercialized form and hard gelatin capsules containing 50 mg doses of diacerhein and 5 6 mg of sodium lauryl sulfate comicronized according to the invention the results obtained have made it possible to show that the improvement in absorption linked to the comicronization of diacerhein comicronized with the surfactant is of the order of 30 compared with the original product these results were confirmed by a second double blind bioequivalence study in 22 healthy volunteers for which the original formulation of 50 mg of diacerhein proved to be comparable to a formulation in accordance with the present invention containing 35 mg of diacerhein and 3 9 mg of sodium lauryl sulfate comicronized as regards the pharmacokinetic characteristics represented by the cmax plasma concentration tmax time necessary to reach cmax and the auc area under the curve values furthermore the tests carried out have shown that the.