diisopropyl ether separate solutions of the acid and free base in such a solvent can be mixed in equivalent amounts whereupon the acid addition salts will usually precipitate because of its relatively low solubility in the nonplanar solvent alternatively the free base can be mixed with an equivalent amount of the acid in the presence of a solvent of moderate polarity for example a lower alkanol a lower alkanone or a lower alkyl ester of a lower alkanoic acid examples of these solvents are ethanol acetone and ethyl acetate respectively subsequent admixture of the resulting solution of acid addition salt with a solvent of relatively low polarity for example diethyl ether or hexane will usually cause precipitation of the acid addition salt these acid addition salts are useful for upgrading the free bases the hydroxy at the 1 methanol position can be esterified by general methods for esterification to produce esters e g the acetate hydrogen succinate and the like the compositions of the present invention are presented for administration to humans and animals in unit dosage forms such as tablets capsules pills powders granules sterile parenteral solutions or suspensions and oral solutions or suspensions and oil in water and water in oil emulsions containing suitable quantities of the compound of formula i for oral administration either solid or fluid unit dosage forms can be prepared for.