gram positive bacteria application_number US 31234303 A description ib 00208 and related compounds exhibits antitumour activity against mammalian tumours such as human lung carcinoma human colon carcinoma human melanoma etc thus the invention includes a method of treating any mammal affected by a malignant tumour sensitive to them which comprises administering to the affected individual a therapeutically effective amount of the compound or a pharmaceutical composition thereof the present invention also relates to pharmaceutical preparations which contain as active ingredient compound ib 00208 or any of its derivatives or a pharmaceutical acceptable salt thereof as well as the processes for its preparation a pharmaceutically acceptable carrier is employed pharmaceutical compositions are typically formulated from the active compound and include any solid tablets pills capsules granules etc or liquid solutions suspensions or emulsions in combination with any carrier or other pharmacologically active compounds the correct dosage of a pharmaceutical composition of ib 00208 or its derivatives will vary according to the particular compound formulation mode of application and sites of host and tumour being treated others factors like age body weight sex diet time of administration rate of excretion condition of the host drug combinations reaction sensitivities and severity of the disease shall be taken into account administration can be carried out continuously or periodically within the maximum tolerated dose the acyl groups can be aliphatic acyl aromatic acyl or mixed aliphatic aromatic acyl thus for example they can be of the formula rco where r.