described above at a temperature below the melting point of the solid solution the solid solution must be kept at a temperature below its melting point to preserve the solid solution during the process of removing the sublimable carrier the sublimable carrier can be removed from the solid solution by for example treating the solid solution deposited on a pharmaceutical carrier particle where applicable in a stream of air preferably heated air in for example a fluidized bed drier in those embodiments in which the solid solution is coated on the surface of a pharmaceutical carrier particle the sublimable carrier can be removed by exposing the coated particles to heat vacuum heat and vacuum or to a stream of heated or non heated air for example in a fluidized bed dryer exposing coated pharmaceutical carrier particles to a stream of air heated or not in a fluidized bed dryer is a preferred means of removing sublimable carrier from solid solution coated on pharmaceutical carrier particles in order to form the microparticles of the present invention on the surface of the carrier particles removal of sublimable carrier from the solid solution whether coated on a pharmaceutical carrier particle or not results in formation of the microparticles of the present invention in another embodiment of the present invention the microparticles of drug or the pharmaceutical.