pharmaceutically acceptable u201d compound or composition means that the compound or composition is not biologically chemically or in any other way incompatible with body chemistry and metabolism and also does not adversely affect the activity of the t3ss inhibitor or any other component that may be present in a composition in such a way that would compromise the desired therapeutic and or preventative benefit to a patient pharmaceutically acceptable carriers useful in the invention include those that are known in the art of preparation of pharmaceutical compositions and include without limitation water physiological ph buffers physiologically compatible salt solutions e g phosphate buffered saline and isotonic solutions pharmaceutical compositions of the invention may also comprise one or more excipients i e compounds or compositions that contribute or enhance a desirable property in a composition other than the active ingredient various aspects of formulating pharmaceutical compositions including examples of various excipients dosages dosage forms modes of administration and the like are known to those skilled in the art of pharmaceutical compositions and also available in standard pharmaceutical texts such as remington 39 s pharmaceutical sciences 18th edition alfonso r gennaro ed mack publishing co easton pa 1990 remington the science and practice of pharmacy volumes 1 amp 2 19th edition alfonso r gennaro ed mack publishing co easton pa 1995 or other standard texts on preparation of pharmaceutical compositions pharmaceutical compositions may be in any of a variety of dosage forms particularly suited for an intended mode.