sulindac and tolmetin or combinations thereof in at least some embodiments the nsaid is piroxicam or tenoxicam or combinations thereof in at least some embodiments the nsaid is tolmetin diclofenac or ketorolac or combinations thereof in at least some embodiments the nsaid 39 s for the treatment and or prevention of rosacea are formulated in a pharmaceutically acceptable carrier which is suitable for use in contact with the skin and or which is desirably capable of dissolving or immersing the therapeutically active amounts of the nsaid in at least some embodiments the nsaid is in the range of about 0 1 5 wt of the formulation additives to such compositions include but are not limited to water surfactants emulsifiers diglycerides triglycerides stabilizing agents thickening agents alpha hydroxy carboxylic acids antioxidants preservatives moisturizers petroleum mineral oil glycerol ethanol propanol isopropanol butanol polymeric gelling agents flavoring colorant and odorant agents and other formulation components used in the art of pharmaceutical and cosmetic formulary it would be apparent to those of ordinary skill in the art of dermatology that the resulting compositions can be in many forms including but not limited to liquids solutions lotions creams pastes emulsions gels soap bars sprays or aerosols such compositions may be applied manually or using various application devices the composition for the treatment and or prevention of rosacea may consist of a single nsaid or a combination of more than one nsaids the composition may further contain additional therapeutic agents which can add to the efficacy of treatment examples of such therapeutic agents are antibiotic antibacterial antiviral anesthetic analgesic antiallergic retinoid anti histamine sulfur immunosuppressant and antiproliferative medications and mixtures thereof in any proportion the concentration of said therapeutic agents may be adopted to exert a therapeutic effect.