addition of 0 5 m acetic acid and lyophilized to the freeze dried sod derivative powder was added a medium higher fatty acid glyceride supplemented with an amphiphilic agent and or a lower alkanol and the mixture is shaken until a macroscopically uniform dispersion is obtained the shaking treatment is carried out using the tomy ur 150p chip type supersonic wave generator tomy seiki the duration of this treatment is not more than 30 seconds a predetermined amount of an amphiphilic agent is added to a given quantity of distilled water and after addition of a lower alkanol as required ultrasonic treatment is carried out to prepare a solution then a solution 4 mg ml of sod derivative powder example of synthesis 1 in 0 02 aqueous ammonium carbonate solution prepared under ice cooling is added to the above solution in equal volumes and the mixture is lyophilized to the resulting freeze dried powder is added the medium higher fatty acid glyceride followed by addition of the lower alkanol as required the mixture is ultrasonicated in an ice water bath for 30 seconds the above procedure gave compositions of the invention as shown in table 4 table 4__________________________________________________________________________ sod derivative prepared informulation example of medium higher amphiphilic agent and or method ofno synthesis 1 fatty acid glyceride lower alkanol preparation__________________________________________________________________________ 1 1 mg panasate u00ae 875 1 ml phosphatidylcholine 0 1 g 1 2 1 mg panasate u00ae 810 0 95 ml unigli u00ae go 206 0 05 ml 2 3 1 mg panasate u00ae 800.