base of formula ii by adding about an equivalent or somewhat more of hydrogen halide to a solution of the free base in an alkanol solvent the salt is precipitated by addition of a nonpolar solvent such as ester chloroform and the like maintaining the starting material in the salt form is desirable since it can be readily repurified and has a crystalline character the novel derivatives of the present invention are antineoplastic agents which can inhibit the growth of transplanted mouse tumors in mice as established by the following tests the animals used were dba 2 mice all of one sex weighing a minimum of 17 g and all within a 3 g weight range there were 5 or 6 animals per test group the tumor transplant was accomplished by intraperitoneal injection of 0 5 ml of dilute ascitic fluid containing 10 6 cells of lymphocytic leukemia p388 various doses of the test derivatives as indicated in table 1 were administered intraperitoneally on days 1 5 and 9 relative to tumor inoculation the animals were weighed and survivors were recorded on a regular basis for 30 days the median survival time and the ratio of survival time for treated t control c animals were calculated the positive control compound was 5 fluorouracil given as a 60 mg kg injection the results of this test.