added after 18 hours the solvent is stripped off 2 u00d7 12 ml of benzene are added to the sample the solvent is again stripped off and the product is dried by means of an oil pump 3 81 mmol of 1 7 dioxa 4 10 diazacyclododecane are dissolved in 50 ml of ch 2 cl 2 1 2 ml of triethylamine are added and 0 1 g of dmap 4 dimethylaminopyridine is added as catalyst 7 64 mmol of pivalyl chloride are subsequently added and the mixture is stirred at room temperature for 18 hours the reaction solution is washed twice with 1n hcl and subsequently twice with saturated nahco 3 solution and dried over mgso 4 and the solvent is stripped off the crude product is purified by column chromatography on silica gel using ch 2 cl 2 methanol 20 1 analogously to example 2 from 1 7 dioxa 4 10 diazacyclododecane and 1 adamantyl acetyl chloride 3 81 mmol of 1 aza 4 7 10 trioxacyclododecane are dissolved in 50 ml of ch 2 cl 2 0 6 ml of triethylamine are added and 0 1 g of dmap 4 dimethylaminopyridine is added as catalyst 3 82 mmol of pivalyl chloride are subsequently added and the mixture is stirred at room temperature for 18 hours the reaction solution is.