dbu to afford compound 6 the chlorine atom of compound 6 is replaced with an amino group by the action of aqueous ammonia to afford compound 7 compound 7 is subsequently subjected to pd pph 3 4 sodium carbonate r u2014 b oh 2 or a compound of formula r u2014 b or u2032 2 in which the radical u2014 b or u2032 2 can be represented as suzuki coupling reaction to afford a compound of formula i u2032 a compound of formula i u2032 is further brominated with n bromosuccinimide nbs to afford a compound of formula i u2033 further suzuki coupling reaction on a compound of formula i u2033 using pd pph 3 4 sodium carbonate r2 b oh 2 or a compound of formula r2 b or u2032 2 in which the radical u2014 b or u2032 2 can be represented as yields a compound of i u2032 u2033 in scheme a r2 is as defined in formula i and r is r1 or a functionality which can be converted into r1 when a compound of formula i in which y is s is desired scheme a process can be modified to obtain the desired product two such modifications are shown in scheme b and b u2032 processes depicted in schemes b and b u2032 are minor variations of scheme a and actual examples using the processes appear below in schemes b and b u2032 r1 and.