ii which may have the more favorable global minimum energy it will be appreciated that there is no required order of addition of mannitol and the auxiliary agent to the solvent or the solvent to the mannitol and or auxiliary agent they may be added separately in any order added in alternating amounts of each or added simultaneously mannitol may be solidified such as by crystallization from a solution comprising mannitol a suitable solvent and an auxiliary agent to obtain modification iii solidification of mannitol modification iii may be achieved by a number of different techniques in one embodiment of the invention mannitol modification iii may be solidified by cooling the solution comprising mannitol a solvent and an auxiliary agent other solidification techniques include evaporation the addition of an anti solvent thermomicroscopy crash cooling of the solution or a combination thereof examples of conditions for methods of the invention are given in example 1 tables 1 and 2 the temperature of the solvent solution was increased to from about 40 u00b0 c to about 60 u00b0 c to aid in the dissolution of the mannitol and or auxiliary agent t in while not necessary the increased temperature may allow for more solids to be loaded in the solution and or for decreasing the time needed to dissolve all solids added in an exemplary embodiment mannitol modification iii may be solidified out of solution at a temperature of less than about 30 u00b0 c in an alternate exemplary embodiment mannitol modification iii may be solidified out of solution in a temperature range of from about 0 u00b0 c to about 45 u00b0 c t out while these ranges are provided as an.