which is herein incorporated by reference departures from complete complementarity are therefore permissible as long as such departures do not completely preclude the capacity of the molecules to form a double stranded structure thus in order for an est nucleic acid molecule or fragment est nucleic acid molecule to serve as a primer or probe it need only be sufficiently complementary in sequence to be able to form a stable double stranded structure under the particular solvent and salt concentrations employed appropriate stringency conditions which promote dna hybridization are for example 6 0 u00d7 sodium chloride sodium citrate ssc at about 45 u00b0 c followed by a wash of 2 0 u00d7 ssc at 50 u00b0 c are known to those skilled in the art or can be found in current protocols in molecular biology john wiley amp sons n y 1989 6 3 1 6 3 6 for example the salt concentration in the wash step can be selected from a low stringency of about 2 0 u00d7 ssc at 50 u00b0 c to a high stringency of about 0 2 u00d7 ssc at 50 u00b0 c in addition the temperature in the wash step can be increased from low stringency conditions at room temperature about 22 u00b0 c to high stringency conditions at about 65 u00b0 c both temperature and salt may be varied or either the temperature or the salt concentration may be held constant while the other variable is changed in a preferred embodiment a nucleic acid of the present invention will specifically hybridize to one or more of the nucleic acid molecules set forth in seq id no 1 through seq id no 5521 or complements thereof under moderately stringent.