hemp regulations in canada for the year 2007 at least 2 500 seeds of cannabis sativa uso 31 were deposited with the national collections of industrial food and marine bacteria ncimb ferguson building craibstone estate bucksburn aberdeen ab21 9 ya scotland u k on feb 5 2015 and have been assigned accession number ncimb 42357 these cannabinoid free plants are phenotypically and chemotypically different to those developed by the applicant through artificial manipulation and differ from those cannabinoid free plants that have been isolated in nature 1 a disrupted morphogenesis of glandular trichomes that according to sirikantaramas et al 20 appear to be essential structures for cannabinoid synthesis and 2 a blockage of one or more biochemical pathways that are crucial for the formation of precursors upstream of cbg the first condition would also seriously affect the synthesis of other secondary metabolites that are produced largely or uniquely in the glandular trichomes in 1991 field grown cannabinoid free plants resulting from gorshkova et al 16 programme were viewed and the bracts and bracteoles of these plants were apparently lacking glandular trichomes also the plants did not exude the characteristic cannabis fragrance this suggests that the volatile mono and sesquiterpenes were not produced in these plants such cannabinoid free plants might therefore have been considered unsuitable for the purpose of breeding a cannabinoid free plant with typical entourage compounds the second condition could also affect metabolites other than cannabinoids as in the case of an obstruction of the basic pathways of common precursors for different classes of end products.