ingredient the doses will be determined by an expert in the field e g clinician or primary care physician according to the type of disease to be treated and the patient 39 s condition or concomitantly with the administration of other active ingredients by way of an example we may indicate doses ranging from 0 1 to 100 mg kg examples of pharmaceutical compositions are those that permit oral parenteral intravenous intramuscular subcutaneous or transdermal administration pharmaceutical compositions suitable for the purpose are tablets rigid or soft capsules powders solutions suspensions syrups and solid forms for extempore liquid preparations compositions for parenteral administration are for example all the intramuscular intravenous and subcutaneous injectable forms and those in the form of solutions suspensions and emulsions we should also mention the forms presenting controlled release of the active ingredient whether as oral administration forms tablets coated with suitable layers microencapsulated powders complexes with cyclodextrins depot forms e g subcutaneous ones as depot injections or implants to a mixture of ketone 9b 4 5 g 18 mmol and n methylpiperazine 15 ml was added drop wise trimethylsilyltrifluoromethane sulphonate 5 7 ml 31 5 mmol in 5 minutes the reaction temperature was brought up to 120 u00b0 c the reaction monitored via tlc was completed in 3 hours the reaction mixture was left to cool at ambient temperature and the resulting solid.