of the number of cell nuclei of one color versus another etc moreover the high power digital image capture can involve additional automated analysis of the captured high resolution images to determine if they meet specified criteria e g the number of chromosomes in a cell nuclei and the image capture can then terminate once a sufficient number of high power images have been acquired for the test e g the operating parameters can specify the number of criteria meeting samples to acquire at high power such as one hundred cells having a specified number of deoxyribonucleic acid dna probe attachments to the nucleus in the case of a fluorescence in situ hybridization fish test at 345 acquired images can be stored the high power power images can be saved for future viewing in the memory of microscope imaging system 100 associated with each stored image can be data related to the coordinates and parameters of the zelles pictured in the digital image fig5 shows a flow diagram of method 500 of codifying the knowledge gained from a pathologist 39 s experience of manually identifying regions of a biological specimen that need to be viewed at higher magnification and are essential in making a diagnostic evaluation this codified knowledge or knowledge base can be used to set operating parameters at 305 of method 300 and can be used to optimize the ability of microscope imaging system 100 to perform many of the operations of method 300 in particular a knowledge base can be used to improve the ability of microscope imaging system 100 to identify parameters at 320 of method 300 that are best able to form groups or clusters of zelles with similar characteristics a knowledge base.