in vitro under the same conditions described in example 1 1 u00d7 10 3 cells per well were cultured in 24 well plates three types of treatment were made a 24 hours after the seeding the cells were separately treated with each one of the following medicines cisplatin 5 u03bcg ml vincristine 0 1 u03bcg ml paclitaxel 5 u03bcg ml and 5 fluorouracil 100 u03bcg ml b 24 hours after the seeding the cells were treated jointly with the 2 5 dihydroxybenzenesulfonic acid potassium salt 100 u03bcm and with each one of the following medicines cisplatin 5 u03bcg ml vincristine 0 1 u03bcg ml paclitaxel 5 u03bcg ml and 5 fluorouracil 100 u03bcg ml c at the time of the seeding day 0 the cells were pre treated with the 2 5 dihydroxybenzenesulfonic acid potassium salt 100 u03bcm next day the cultures were treated also with each one of the following medicines cisplatin 5 u03bcg ml vincristine 0 1 u03bcg ml paclitaxel 5 u03bcg ml and 5 fluorouracil 100 u03bcg ml the control cultures did not receive treatment for 2 days after 48 hours day 2 the cells of identical shape to the ones used in example 1 were evaluated in all the cultures this study was carried out in triplicate independent experiments repeated three times fig5 a b c and d shows the histograms of the experiments performed to evaluate the effect of the 2 5 dihydroxybenzenesulfonic acid in the potentiation of the different cytostatic medicines treatment with cisplatin vincristine and 5 fluorouracil produces an.