example an average of the intensities of the cmcd may be taken over the entire cmcd sample set for any specific sample region of the cmcd a correction may be determined by subtracting the sample region intensity from the average that correction may then be applied to the corresponding sample region of the emcd a correction as described above for step 20 of fig1 was applied to fig8 and the result is demonstrated in fig9 it is apparent that the correction of the experimental data as displayed in fig9 results in the ready clustering of the genotypes a set of emcd shown in tabular form is presented in fig1 in fig1 the first column displays the previously verified genotype of the samples the second column represents the call made based on experimental data that was not corrected for assay system noise using calibration data finally the third column represents the call made based on experimental data that was corrected for assay system noise using calibration data as can be seen in the heading the calls made using the uncorrected experimental data were correct 40 of the time while the calls made using the corrected experimental data were correct 90 of the time moreover the samples marked u201c ntc u201d are no template controls are negative controls for which no melt curve would be expected the corrected mcd consistently assigns the negative controls correctly accordingly various embodiments of methods for the analysis of dissociation melt curve data as depicted in fig1 are effective in making determinations of genotyping where the melting temperatures in an experimental set of data are different by only.