beads s 807 move the supernatant which contains the eluted dna molecules to merge mix with a dispensed pcr reagent droplet and then move mixed droplet to a temperature zone where the qpcr measurement can be performed s 808 move the measured droplet s to a waste storage location on the device fig8 shows only one of the many possible applications for carrying out biochemical analyses by simply loading a dmf device as described with raw material and the corresponding reagents the dmf device provides many functions such as extracting analytes from the raw material and carrying out detection on them examples include but are not limited to blood chemistry measurements such as blood gases glucose electrolytes urea etc in whole blood the measurement of sweat electrolytes in sweat for cystic fibrosis diagnostics and the measurement of interleukin 1 beta il 1 u03b2 and interleukin 8 il 8 etc in saliva to detect oral squamous cell carcinoma etc it should be pointed out that the use of heating electrodes inside a dmf device offer great advantages comparing to external heaters for example saving room for other actuators such as magnets and clearing the path for things like laser excitation and fluorescence detection to name two it should be mentioned that the above described examples and the above mentioned advantages are by no means exhaustive the flexible nature of this invention can be utilized for many applications and does have a lot of advantages comparing other technologies such as microfluidic devices with only the external temperature controls all printed patents and publications referred to in this application are hereby incorporated herein in their entirely while the preferred embodiments of the invention have been illustrated and described it will be.