vein port 12 further includes a plurality of radiation sources 34 and a controller 36 and catheter 14 includes a plurality of radiation sources 38 and a controller 40 radiation sources 34 and 38 are generally configured to treat or to modify a material 42 such as a pharmacological compound e g a drug that is introduced into port 12 and catheter 14 respectively in some embodiments radiation sources 34 and 38 are capable of modifying material 42 by generating and emitting energy one type of energy is ultraviolet light about 100 to about 400 nm e g uv c light about 100 to about 280 nm radiation sources 34 and 38 can emit energy sufficient to modify material 42 for example radiation sources 34 and 38 can emit a sufficient dosage of ultraviolet light that can inactivate kill reduce neutralize inhibit or otherwise modify organisms in material 42 such as bacteria viruses yeasts protozoa and molds controllers 36 and 40 are configured to control radiation sources 34 and 38 respectively controllers 36 and 40 include a power source e g a micro cell or a battery a sensor and a programmable microprocessor chip that are in electrical communication with the radiation sources controllers 36 and 40 are capable of detecting material 42 that is introduced into port 12 and catheter 14 respectively and activating radiation sources 34 and 38 according to a predetermined manner in embodiments after controller 36 detects a material in port 12 the controller can activate radiation sources 34 for.