3 4 1 cyanocyclopropan 1 yl phenyl 2 oxooxazolidin 5 ylmethyl 2 s chloropropionamide 193 mg was prepared from 5 s aminomethyl 3 4 1 cyanocyclopropan 1 yl phenyl oxazolidin 2 one 150 mg and s chloropropionic acid 82 2 mg in the same manner as described for example 62 ms ei m z 347 m hrms ei for c17h18cln3o3 m calcd 347 1037 found 347 1063 to a solution of n 5 s 3 4 1 cyanocyclopropan 1 yl phenyl 2 oxooxazolidin 5 ylmethyl acetamide 140 mg in tetrahydrofuran 5 ml was added iodomethane 73 u03bcl and potassium t butoxide 78 7 mg at room temperature the mixture was stirred at the same temperature for 1 hour after quenching the reaction by addition of 5 hydrochloric acid the mixture was extracted with ethyl acetate the organic extracts to were washed with 5 sodium hydrogencarbonate solution 5 sodium thiosulfate solution and brine dried over anhydrous magnesium sulfate filtered and then concentrated in vacuo flash chromatography silica ethyl acetate methanol 19 1 of the residue gave n 5 s 3 4 1 cyanocyclopropan 1 yl phenyl 2 oxooxazolidin 5 ylmethyl n methylacetamide 139 mg ms ei m z 313 m hrms ei for c17h19n3o3 m calcd 313 1426 found 313 1433 the title compounds n benzoyloxy n 5 s 3 4 1 cyanocyclopropan 1 yl phenyl 2 oxooxazolidin 5 ylmethyl acetamide 127 mg and n benzoyloxy o 5 s 3 4 1 cyanocyclopropan 1.