47 1 55 4 nipwb 50 28 6 45 7 50 0 100 16 5 44 4 75 7 the salts of sulfodehydroabietic acid with bismuth or zinc have obvious inhibition effect p lt 0 01 on total amount of hydrochloric acid of gastric juice and the pepsin activity when the treatment dose is 50 100 mg kg the inhibition ratio for total acid amount is over 44 the inhibiting ratio for pepsin activity is over 40 measurement of the acute toxicity of salts of sulfodehydroabietic acid with bismuth nipwb for oral administration to mice 20 second grade kunming mice were provided each weighing 20 1 u00b1 1 3 g 10 male and 10 female medicine was orally administered to them by twice with the maximal dose of 50 ml kg the solvent was 0 5 mc the abnormal reaction and the death after oral administration were recorded in details observing was continued for 14 days and the dead bodies were anatomized no abnormal reaction and death occurred during 14 days continuous observing after the oral administration of 8000 mg kg nipwz to mice ld 50 u2267 8000 mg kg measurement of the acute toxicity of salts of sulfodehydroabietic acid with zinc nipwz for oral administration to mice 50 second grade kunming mice were provided each weighing 20 0 u00b1 1 2 g randomly divided into.