superbase a boronic acid forming agent boronation solvent and boronation reaction temperature u201c superbase u201d means an extremely strong base such as combination of an organolithium reagent of formula rli where r is an alkyl or aryl group having 1 12 carbons and a bulky potassium alkoxide such as potassium tert butoxide or potassium tert pentoxide and the like u201c boronic acid forming agent u201d means a trialkyl boronate such as trimethyl borate triethyl borate tripropyl borate triisopropyl borate tributylborate and the like u201c boronation solvent u201d means a solvent an ether solvent such as diethyl ether thf 2 methyltetrahydrofuran mtbe dimethoxyethane and the like u201c suzuki coupling conditions u201d mean conditions using a suzuki coupling solvent suzuki coupling catalyst and suzuki coupling reaction temperature u201c suzuki coupling solvent u201d means an alcohol solvent with a boiling point of isopropyl alcohol such as n propyl alcohol n butyl alcohol or the like polar aprotic solvent such as dimethylformamide 1 methyl 2 pyrrolidone dimethylsulfoxide or the like ether solvent such as thf 2 methylthf dimethoxyethane mtbe or the like or mixture of any of the aforesaid mentioned solvents and water or toluene u201c suzuki coupling catalyst u201d means a pd catalyst such as pd pph 3.