the filtrate is distilled off evaporate solvent completely u vaccum at lt 50 u00b0 c temperature reaction mass is cooled to 25 30 u00b0 c to this dm water 400 ml is added stirred for 1 hr at 25 30 u00b0 c the solid is filtered to give 105 gr of 3 fluoro 4 morpholinyl aniline 3 fluoro 4 morpholinyl aniline 100 gr is mixed with r epichlorohydrin 59 gr tert butanol 500 ml is added and heated for 16 hrs at reflux temperature the solvent is distilled to give 156 gr of n 3 chloro 2 r hydroxy propyl 3 fluoro 4 morpholinyl aniline n 3 chloro 2 r hydroxypropyl 3 fluoro 4 morpholinyl aniline 156 gr is dissolved in methylene dichloride 1 5 lt diimidazolyl carbonyl 87 4 gr is added at room temperature stirred for 24 hrs at 25 30 u00b0 c then washed thrice with water 750 ml u00d7 3 dry over na 2 so 4 distilled methylene dichloride to give 156 gr of crude 5r 5 chloromethyl 3 3 fluoro 4 4 morpholinyl phenyl 2 oxazolidinone which is further isolated and crystallized from n butyl acetate 100 ml to give 83 gr of 5r 5 chloromethyl 3 3 fluoro 4 morpholinophenyl oxazolidin 2 one 5r 5 chloromethyl 3 3 fluoro 4 morpholinophenyl oxazolidin 2 one 83 gr is mixed with sodium acetate 43 and dimethyl formamide 320 ml.