involved in lignocellulosic biomass dissolution a set of representative natural amino acids with suitable structures and functional groups some essential nutrients represented by choline chloride and nicotinic acid as well as different natural acids present in fruits and vegetables were tested as liquid phase promoters in one example the preparation of the new solvents was done by mixing both starting materials in the solid state followed by melting them at 60 degrees celsius for mixtures containing lactic or oxalic acid or at 130 degrees celsius for nicotinic and malic acid mixtures it is noticeable that the melting temperature or glass transition temperature as some mixtures do not show a melting point was always found to be lower than the melting point of any of the starting materials the higher the temperature during mixing and the better the mixing the faster the melting was observed nevertheless higher thermal stability was found for mixtures obtained at lower temperatures for longer times once a clear and transparent liquid was formed with no evidence of solid particles the mixture was cooled down and differential scanning calorimetry dsc analysis was carried out to determine the phase transition temperature of the formed liquids water content was always less than 1 wt a more detailed description of an example of an experimental procedure is included infra in the section supplemental information tables 1a c show the u2018 hydrogen bond donor u2019 u2014 u2018 hydrogen bond acceptor u2019 combinations which were resulting in clear liquids table 1a liquids at the set temperature.