the cassette is disposable and typically discarded after a single use or therapy reducing risks associated with contamination referring now to fig1 a to 1f a first configuration for the components of system 10 is illustrated by configuration 350 as discussed herein in one embodiment the pumping technology used for system 10 is a peristaltic pump it is expressly contemplated however that many features and embodiments discusses herein can be used with peristaltic pumps volumetric pumps pumps operated pneumatically pumps operated mechanically pumps operated hydraulically and any combination thereof the component features discussed in connection configuration 350 and indeed in connection with configurations 370 and 390 shown in connection with fig2 a to 2f and 3 a to 3 f respectfully are applicable to any of the different types of pumping technologies just previously described indeed while cassette 50 is shown in connection with each of configuration 350 370 and 390 as seen in fig1 a configuration 350 of system 10 includes supply bags 14 16 and 22 and drain bag 24 those bags are connected fluidly to machine or unit 60 via lines 28 54 20 and 32 respectfully as seen in fig1 c additionally fig1 a further illustrates that configuration 350 of system 10 includes an organizational mat 352 which is shown and discussed in more detail in connection with fig1 f fig1 a further illustrates that configuration 350 can be placed partly on a desk or nightstand with drain bag 24 being placed on the floor in the illustrated embodiment supply bags 14 16 and 22 and cassette 50 are loaded and maintained in an at least substantially horizontal configuration referring now to fig1 b machine or unit 60 is illustrated in more detail here unit.