to the reactions shown in scheme ii thus compounds may be prepared from readily available substituted or unsubstituted 4 haloquinoline compounds by allowing them to react with a wittig reagent such as an alkyl triphenylphosphonate generated from an alkyltriphenylphosphonium halide plus a base such as n butyllithium in an organic solvent such as tetrahydrofuran the resulting 4 alkylquinoline can be converted to a 4 alkyl 2 haloquinoline by treatment with an oxidizing agent such as m chloroperbenzoic acid mcpba in an appropriate solvent such as chloroform to give the corresponding 4 alkylquinoline n oxide followed by reaction with a halogenating agent such as phosphorus oxychloride to give a 4 alkyl 2 haloquinoline of formula iva reaction of 2 haloquinoline iva with amines of formula v as described above yields compounds of this invention wherein r 1 r 6 are as defined above r 1 is alkyl of 1 to 4 carbon atoms and x is halogen the disclosures in this application of all articles and references including patents are incorporated herein by reference those having skill in the art will recognize that the starting materials may be varied and additional steps employed to produce compounds encompassed by the present invention the invention is illustrated further by the following examples which are not to be construed as limiting the invention in scope or spirit to the specific.