74 of cutter stop 72 may be designed to match the leading profile of cutter 38 fig6 and 7 depending on the means used to advance cutter 38 cutter stop 72 may also provide tactile feedback to a surgeon once cutter 38 comes into contact with cutter stop 72 after a sample has been severed however if as known in the art a computer software program is used to control advancement of cutter 38 the surgeon will not be provided with tactile feedback by contact between cutter 38 and cutter stop 72 as illustrated in fig2 a hub 76 having a proximal portion 78 and a distal portion 80 may be located on proximal portion 32 of needle assembly 30 hub 76 assists in mounting needle assembly 30 to handle 20 or other any other suitable support hub 76 may detachably mount on handle 20 in order to allow disposable needle assembly 30 to be removed from the multiple use handle 20 after surgery hub 76 may also include a flange 82 on its distal portion 80 flange 82 may snap into a rib or similar retaining element not shown of handle 20 or another suitable support hub 76 may also include a vacuum manifold 84 that provides a connection between the vacuum source and vacuum lumen 52 hub 76 may also allow second vacuum line 54 to connect with cutter 38 so that axial suction may be communicated to cutter 38 in one aspect consistent with the process of the current invention a distal tissue piercing tip 86 having a proximal portion 88 and a distal portion.