disclosed the system 10 includes a plasma device 12 that is coupled to a power source 14 an ionizable media source 16 and a precursor source 18 power source 14 includes any suitable components for delivering power or matching impedance to plasma device 12 more particularly the power source 14 may be any radio frequency generator or other suitable power source capable of producing power to ignite the ionizable media to generate plasma the plasma device 12 may be utilized as an electrosurgical pencil for application of plasma to tissue and the power source 14 may be an electrosurgical generator that is adapted to supply the device 12 with electrical power at a frequency from about 0 1 mhz to about 2 450 mhz and in another embodiment from about 1 mhz to about 13 56 mhz the plasma may also be ignited by using continuous or pulsed direct current dc electrical energy the precursor source 18 may be a bubbler or a nebulizer configured to aerosolize precursor feedstocks prior to introduction thereof into the device 12 the precursor source 18 may also be a micro droplet or injector system capable of generating predetermined refined droplet volume of the precursor feedstock from about 1 femtoliter to about 1 nanoliter in volume the precursor source 18 may also include a microfluidic device a piezoelectric pump or an ultrasonic vaporizer the system 10 provides a flow of plasma through the device 12 to a workpiece u201c w u201d e g tissue plasma feedstocks which include ionizable media and precursor feedstocks are.