acetic acid or ethanolic hydrochloric acid or by hydrogenation using palladium on carbon or platinum oxide as catalyst the product ix is purified by typical purification procedures of recrystallization or column chromatography the amine ix can be derivatized to yield a variety of products generally represented by the formula x for example amides can be prepared by treatment of ix with alkyl or aryl acid halides typically chlorides or anhydrides in the presence of base in an inert solvent typically organic bases such as triethylamine diisopropylethylamine or pyridine can be used in inert solvents such as tetrahydrofuran acetonitrile or dioxane at a temperature range of ambient to reflux temperature for 2 24 hr pyridine can be used alone as solvent and base acylation catalysts such as dimethylaminopyridine dmap can be added to facilitate the reaction typical work up procedure includes removal of solvent followed by partitioning of the product between aqueous and organic solvents such as ether ethyl acetate or methylene chloride depending upon the reactivity of the acid halide the product typically consists of a monoamide diamide or a mixture of the two these can be purified resolved typically by column chromatography mono or dialkyl amino derivatives of ix can be prepared by its treatment with alkyl or haloalkyl halides in the presence of base such as potassium or sodium carbonate or sodium hydride in an inert solvent such as tertahydrofuran or dimethylformamide at a temperature of ambient to 120 u00b0 c for 2 24 hr mono or dicarbamoyl derivatives of ix can be prepared by its treatment with alkylhaloformates such as methyl or ethylchloroformate in the presence of base such as potassium or sodium carbonate in an inert solvent such as tertahydrofuran or dimethylformamide.