qt interval over a 24 hour period with no score equal to the minimum or maximum qt interval noted during the test exercise period or the minimum or maximum qt interval noted during the initial observation period 19 qrs duration during normal awake hours stays within a range of u00b1 1 0 sd without change in the mean qrs duration over a 24 hour period with no score equal to the maximum qrs duration noted during the test exercise period or the maximum qrs duration noted during the initial observation period 20 st segment depression or elevation during normal awake hours stays within a range of u00b1 1 0 sd without change in the mean st segment depression or elevation over a 24 hour period with no score equal to the maximum st segment depression or elevation noted during the test exercise period or the maximum st segment depression or elevation noted during the initial observation period and 21 temperature during normal awake hours stays within a range of u00b1 1 0 sd without change in the mean temperature over a 24 hour period with no score equal to the minimum or maximum temperature score noted during the test exercise period or the minimum or maximum temperature noted during the initial observation period for an exemplary non ambulatory patient with no major impairments of the major limbs reference exercise can be defined as follows 1 heart rate increases by 10 bpm for each one point increase in activity score note that to.