synthetic peptides and antibodies which are potent chemotactic agents for human neutrophils and methods for their use the specificity of these peptides is amino acid sequence specific for binding to a heretofore unidentified receptor on the surface of neutrophils neutrophil response to this peptide is specific since monocytes and fibroblasts do not show any expression of this receptor antibodies against these peptides block the chemotactic response such antibodies are useful to modulate neutrophil recruitment to a wound site for enhancing or inhibiting inflammation and early effects of wound healing application_number US 33059494 A description the peptides of the present invention were synthesized on a milligen biosearch automated peptide synthesizer u00ae model 9600 using t boc chemistry ficoll hypaque mono poly resolving medium u2122 was obtained from icn biomedicals costa mesa calif dulbecco vogt modified medium dmem ham 39 s f 12 and powdered hanks balanced salt solution hbss were obtained from gibco grand island n y diff quik u00ae staining kits were obtained from baxter scientific products houston tex multiwell chemotaxis chambers and 3 0 u03bcm nucleopore u2122 pvp free filters were obtained from neuro probe cabin john md whatman gf c filters from millipore were used in the receptor binding assays other reagent grade chemicals were obtained from sigma chemical co st louis mo except as noted human neutrophils were isolated from blood of healthy volunteers drawn into one tenth volume of trisodium citrate the neutrophils were isolated from the blood using established ficoll hypaque mono poly resolving medium u2122 protocol kalmer et al 1988 specifically incorporated herein by reference the cells were washed in hbss containing 20 mm hepes ph 7 4 hhbss pelleted by centrifugation 600 u00d7 g and resuspended into hhbss at the indicated density trypan blue exclusion.