than the first chamber the first chamber needs a longer period for heating owing to the larger quantity of medical substance as is evident from the temperature curve line 3 during the first ten minutes the first chamber reaches the sterilisation temperature much later and is also held at this sterilisation temperature for a shorter period line 3 after reaching the end of the predetermined hold time at the sterilisation temperature for the multiple chamber recipient or for the first chamber the multiple chamber recipient is cooled down during this the second chamber or the contents of the second chamber cools faster line 1 owing to the smaller quantity of medical substance relative to that of the first chamber line 3 the longer hold time of the second chamber at the sterilisation temperature causes a higher formation of degradation products and also leads to an elevated f value in the second chamber which is superfluous in terms of sterilisation this is shown in fig2 fig2 shows the f o curve during the heat sterilisation according to fig1 as can be clearly seen here in the second chamber line 1 an f 0 value is obtained that is almost double that in chamber 1 line 3 the f o.