s 2 h 4 10 m 8h 3 40 m 4h 2 93 m 2h 1 80 m 5h 1 21 m 13h ms fd m z 747 m in a manner similar to the preparation in example 1 reaction of raloxifene 1 5 g 2 94 mmol sodium hydride 0 47 g 12 mmol and pho 2 pocl 1 53 ml 7 35 mmol followed by acidification gave the pictured product as a white foam 1 h nmr 300 mhz dmso d 6 8 21 s 1h 7 78 d j 8 6 hz 2h 7 2 7 6 series of m 26 h 7 02 d j 8 8 hz 2h 4 50 m 2h 3 42 m 4h 3 95 m 2h 1 75 m 5h 1 37 m 1h ms fab 938 m hcl in a manner similar to the preparation of example 1 reaction of raloxifene 2 0 g 3 92 mmol sodium hydride 0 63 g 16 mmol and ph 2 pocl 1 90 ml 10 0 mmol followed by acidification gave the pictured product as a white foam 39 h nmr 300 mh 2 8 13 s 1h 7 20 7 99 series of m 28h 6 96 d j 8 5 hz 2h 4 51 m 2h 3 49 m 4h 2 95 m 2h 1 80 m 5h 1 38 m 1h ms fd m z 874 m in the examples.