of 0 30 by weight and colloidal silica by weight topically to a surface of a contaminated organ embodiments disclosed herein are also useful against bacteria that are in a persistent state that is bacteria that have never been cultured in a lab once structural integrity of a biofilm is destroyed by exposure to a formulation disclosed herein the microbes die and the biofilm is disrupted bacteria and other pathogens exposed to formulation embodiments disclosed herein do not develop a resistance to the formulations formulation and method embodiments disclosed herein are effective against all bacteria biofilm prions and other infectious agents formulation embodiments disclosed herein are exposed to the bacterial and other pathogen structures that are desiccated by formulation embodiments disclosed herein the structures desiccated include cell wall plasma membrane s layers glycocalyx flagella fimbriae and pili structures of both gram negative and gram positive bacteria are desiccated and susceptible to destruction while bacteria are described it is understood that all microbes in a biofilm are susceptible to destruction by desiccation by a formulation embodiment disclosed herein additionally formulation embodiments disclosed herein prevent damage done by a destructive inflammation immune response initiated by necrotizing tissue by eliminating the necrotizing tissue before the response is prompted elimination of the necrotic tissue prevents the body from initiating a destructive inflammatory immune response formulation embodiments disclosed herein are effective for killing bacteria that are antibiotic resistant such as mrsa formulations disclosed herein are also effective in killing bacteria that.