one or more vitamins for administration as an inhalation spray it is possible to use sprays in which the active ingredient is either dissolved or suspended in a propellant gas or propellant gas mixture for example co 2 or chlorofluorocarbons the active ingredient is advantageously used here in micronized form in which case one or more additional physiologically acceptable solvents may be present for example ethanol inhalation solutions can be administered with the aid of conventional inhalers accordingly the antagonists are preferably administered in doses between about 0 001 mg and 200 mg more preferably between about 0 01 mg and 100 mg even more preferably between about 0 01 mg and 50 mg and in particular between 0 01 and 30 mg per dose unit the daily dose is preferably more than or equal to about 0 0001 mg kg more preferably more than or equal to about 0 001 mg kg even more preferably more than or equal to about 0 005 mg kg more than or equal to about 0 01 mg kg or more than or equal to about 0 1 mg kg the daily dose is preferably less than or equal to about 30 mg kg more preferably less than or equal to about 20 mg kg even more preferably less than or equal to about 15 mg kg less than or equal to about 5 mg kg or less than or equal to about 1 mg kg of body weight 1 hood j d cheresh d a role of integrins in cell invasion and migration nat rev cancer 2002 2 91 100 2 schuppan d ruehl m somasundararn r hahn e g matrix as a modulator of hepatic fibrogenesis sem liver dis 2001 21 351 72 3 carloni v romanelli r g pinzani.