parr shaker at 30 u00b0 c in the presence of a slurry of raney nickel a 7000 4 2 g after 3 hours uptake of hydrogen has ceased the mixture is cooled to 20 u00b0 c the atmosphere is vented and exchanged for nitrogen the slurry is filtered through celite and concentrated in vacuo to give 9 25 g of 4r cis 6 2 aminoethyl n butyl n 2 2 trimethyl 1 3 dioxane 4 acetamide as an oil in a process analogous to example 1 4r cis 6 2 aminoethyl n butyl n 2 2 trimethyl 1 3 dioxane 4 acetamide is converted to r r r n butyl 5 4 fluorophenyl u03b2 u03b4 dihydroxy n methyl 2 1 methylethyl 4 phenyl 3 phenylamino carbonyl 1h pyrrole 1 heptanamide which is further converted to r r r 2 4 fluorophenyl u03b2 u03b4 dihydroxy 5 1 methylethyl 3 phenyl 4 phenylamino carbonyl 1h pyrrole 1 heptanoic acid hemi calcium salt to a stirred 10 u00b0 c solution of n 1 1 dimethylethyl n phenylmethylacetamide prepared from n 1 1 dimethylethyl n phenylmethyl amine and acetyl chloride by refluxing for 2 hours in toluene 102 5 g 0 5 mol in tetrahydrofuran 0 5 l is slowly added a solution of lithium diisopropylamide in tetrahydrofuran heptane 0 25 l.