and l glutamine at 37 u00b0 c in 95 air and 5 co2 insertion of gelatin sponge and tumor transplantation mice were anesthetized with ether and swabbed with 70 ethanol on the back and then a 10 mm incision was made in the right flank skin at the pelvic region the mice had a piece of gelatin sponge 10 u00d7 5 u00d7 3 mm surgically inserted into the subcutaneous pocket at the place of the incision after closing the incision with a clip 0 1 ml of tumor cell suspension containing 1 u00d7 10 5 cells was injected into the site of gelatin sponge insertion measurement of tumor growth after inoculation was performed twice per week medication of sod g a preparation of sod g used in the study contained 1000iu sod activity per g of preparation trade name oxykine as controls groups of mice treated with physiological saline solution and also treated with gliadin were prepared sod g was administered to the mice at an oral daily dose of 10 mg kg of body weight 10 ml of saline from day 2 nd to the 27 th making the transplant day the zero day each group consisted of 7 to 9 mice effect of sod g on growth of tumor transplanted simultaneously with gelatin sponge was shown in table 1 experiment a the average growth curve of the sod g treated group was compared with those of saline and gliadin as shown in fig1 tumor growth was.