20 ml of water and ethyl acetate extractions the resulting ethyl acetate solution was dried and treated with 1 ml of 5n ethanolic hydrochloric acid some methanol was added to redissolve precipitated material and the water and methanol solvents were removed on a rotary evaporator the remaining residue was rubbed under ether the evaporation was repeated and the resulting residue was pump dried in result 1 15 g of solid remained having a melting point of 59 u00b0 63 u00b0 c thereafter 15 ml of warm acetonitrile was added to the solid the solid therefore crystallized leaving a colorless material weighing 0 92 g a 64 yield having a melting point of 195 u00b0 197 u00b0 u03b1 d 25 u00b0 59 0 u00b0 c 1 methanol analysis calculated for c 27 h 28 f 3 n 3 o 3 2hcl 0 5h 2 o c 55 77 h 5 37 n 7 23 cl 12 20 found c 55 61 h 5 44 n 7 25 cl 12 27 1 2 5 mmol of a first solute 3r cis 1 3 4 5 tetrahydro 1 formylmethyl 3 hydroxy 4 4 methoxyphenyl 6 trifluoromethyl 2h 1 benzazepin 2 one described in steps 1 and 2 example 1 2 0 37 g 3 0 mmol of a second solute 4 2 aminoethyl pyridine and this solution was stirred treated with a cold slurry of 0 2 g of a catalyst 10 palladium on charcoal in 5 ml of methanol fitted with a 5 l hydrogen balloon and stirred for 20 hours at room temperature at that.