u2212 30 u2212 15 and 0 minutes subjects were then asked to swallow the capsules of the test supplement or an identical looking placebo the administered supplement is a novel 2 9 g dose blend of l lysine hcl l arginine hcl oxo proline n acetyl l cysteine l glutamine and schizonepeta aerial parts powder blood was drawn at 15 30 60 and 90 and 120 minutes for assay human gh was measured at each time point using the siemens immulite 2000 intra assay cv was 3 72 inter assay cv was 5 70 and the detection limit for gh was 0 05 ng ml mean growth hormone increased eight fold over baseline equivalent to 682 after the supplement from 0 17 at baseline to 1 33 ng ml at 120 minutes compared to a mean decrease of 52 after placebo from 0 93 to 0 45 ng ml fig1 the mean change in gh levels from baseline to 120 minutes gh at 120 minutes minus gh at 0 minutes was 1 15 95 ci 0 17 2 14 ng ml after the supplement versus u2212 0 48 u2212 1 47 0 50 ng ml after the placebo demonstrating a statistically significant differential effect p 0 01 after the supplement the mean auc for gh across 120 minutes was 20 43 95 ci 19 90 20 95 ng ml min which was significantly.