controlled by a variac through the bulb for 3 5 s 2 mg coating or 5 s 10 mg coating affords thermal vapor including aerosol which is collected on the glass tube walls when desired the system is flushed through with argon prior to volatilization reverse phase hplc analysis with detection by absorption of 225 nm light is used to determine the purity of the aerosol table 1 which follows provides data from drugs volatilized using the above recited general procedure to obtain higher purity aerosols one can coat a lesser amount of drug yielding a thinner film to heat a linear decrease in film thickness is associated with a linear decrease in impurities a solution of 22 0 mg paroxetine in 200 u03bcl dichloromethane was spread out in a thin layer on the central portion of a 3 5 cm u00d7 7 cm sheet of aluminum foil the dichloromethane was allowed to evaporate assuming a drug density of about 1 g cc the calculated thickness of the paroxetine thin layer on the 24 5 cm 2 aluminum solid support after solvent evaporation is about 9 0 microns the aluminum foil was wrapped around a 300 watt halogen tube which was inserted into a t shaped glass tube both of the openings of the.