aqueous solvents and suspensions witepsol macrogol tween cacao butter laurin butter glycerogelatin etc may be used for a suppository base the preferred administration dose of the extract of the present invention may be different depending on condition and body weight of a patient severity of disease drug form administration route and administration period and be selected appropriately by those skilled in the art for preferable effects the extract of the present invention may be administered in a dose of from about 0 0001 to about 100 mg kg body weight per day preferably from about 0 001 to about 100 mg kg the administration frequency may be once a day or a few times a day the administration dose is not intended to limit the scope of the present invention in any way the present invention provides a health functional food comprising the extract having preventive effect on thrombotic disorders and a sitologically acceptable dietary supplement additive examples of health functional foods to which the extract of lindera obtusiloba can be added include a variety of general foods beverages gum teas vitamin complexes etc also the extract of lindera obtusiloba may be added to foods or beverages for the purpose of preventing thrombus formation an amount of the extract in foods or beverages may be 0 01 to 15 by weight of total food weight and an amount of the extract in health beverages may be 0 02 to 5 g preferably 0 3 to 1 g based on 100 g of a health beverage composition the health.