1 4 dioxane 790 ml was added 2 n naoh solution 18 6 gms of naoh in 450 0 ml of di water the reaction mass was heated to 40 45 u00b0 c and further stirred for 33 hours the reaction mass was cooled to 25 30 u00b0 c and quenched in water 7 9 lit the reaction mass was cooled to 10 15 u00b0 c and acidified with conc hcl the solid was isolated by filtration and dried to yield 72 0 gms of the title compound i compound i was further purified in n methyl pyrrolidone n heptane followed by dmso n heptane to obtain 65 0 gms of the title compound i to a stirred solution of s methyl 2 hydroxy 3 methoxy 3 3 diphenylpropionate compound iv 50 gms 0 174 moles and potassium carbonate 26 36 gms 0 191 moles in dmf 500 ml was added 4 6 dimethoxy 2 methyl sulfonyl pyrimidine compound iii r methoxy 41 42 gms 0 191 moles in a dry flask under nitrogen at 25 30 u00b0 c the reaction mass was heated to 90 92 u00b0 c and further stirred for 1 5 hour the reaction mass was charged with ethyl acetate 1 5 lit the organic layer was washed with 2n citric acid 500.