procedures both as to reactants and as to reaction conditions and techniques r naproxen can j chem 72 1 142 5 1994 260 g methylene chloride 3 33 kg and dmf 8 2 ml are added to a reactor oxalyl chloride 191 8 g is slowly added to this mixture after addition of the oxalyl chloride the slurry is stirred at 5 to 10 u00b0 and then slowly warmed to 20 25 u00b0 the resulting mixture is concentrated to remove the methylene chloride branched octane is added to the concentrate and the mixture is again concentrated more branched octane is added to the concentrate and the mixture is cooled to 0 u00b0 and stirred to crystallize the crystal slurry is filtered the crystal cake is washed with octane and dried at 20 25 u00b0 to obtain the title compound the filtrate from the first crop is concentrated branched octane is added and the mixture is cooled and stirred to obtain a second crop of the title compound the slurry is filtered the crystal cake is washed with branched octane and dried at 20 25 u00b0 a mixture of 4h imidazo 4 5 1 ij quinolin 2 1h one i j heterocyclic chem 19 837 49 1982 1 0g 5 8mmol in dmf 10 ml is cooled to 0 u00b0 and treated with potassium t butoxide in thf 1 98 m 3 2 ml 6 3.