such pressure such a system permits delivery of approximately 1 to 50 cc of fluid such as oxygen superaturated fluid per minute with the high pressure delivery device described herein such flows can be safely delivered to the patient with great accuracy of placement in tortuous vasculature and reduced risk of bubble formation or trauma to the vasculature referring now to fig2 a portion of proximal segment 10 of guidewire 108 is shown proximal segment 10 includes a first tube 12 which defines fluid lumen 14 tube 12 is made of bio compatible material has the appropriate dimensions and the appropriate burst strength flexibility torque transfer and kink resistance characteristics selectable by a person of skill in the art for use in the particular intended application tube 12 may be coated over most of its length with a thin film of low friction biocompatible coating 13 such as ptfe tube 12 and lumen 14 open at proximal end 16 for connection to source 102 shown in fig1 in one embodiment tube 12 of proximal segment 10 is preferably a 304 stainless steel tube having an outside diameter of approximately 0 0140 u2033 an inside diameter of approximately 0 009 u2033 and a length of approximately 150 cm tube 12 preferably has a burst strength exceeding about 10 000 psi tube 12 preferably also has a 0 0002 u2033 to 0 0005 u2033 thick coating 13 of ptfe over its full length except for a few centimeters at each end if necessary to avoid kinking during the initial part of a procedure a support wire or stylet not shown may be inserted in tube 12 the support wire or stylet would.