fingers and toes the higher blood flow to the areas treated with the active ingredients also improve skin early ageing particularly face and neck skin cellulitis like derm hypoderm panniculopathies and stretch marks striae distensae moreover the higher blood supply also acts favorably on non glabrous skin such as scalp and is useful in the treatment of the primitive and secondary alopecias in the cosmetic fields the main uses of the products object of invention relate the ageing of the skin and cellulitis which affects a high percentage of the population in the industrialized countries by way of example of the above described uses 20 patients suffering from chronic venous insufficiency stage i were subdivided into two groups and treated with a formulation containing 1 5 esculoside or with placebo for 3 months twice a day administering the product from the trocanterian area to the ankle the patients before the long term treatment were checked to evaluate their response capability by an acute test by means of videocapillaroscopic measurement of the increase in cutaneous microcirculation the capillary density in the group treated with placebo measured 20 minutes after the treatment was 8 6 u00b1 2 2 whereas in the group treated with esculoside it was 18 6 u00b1 3 1 with p lt 0 01 calculated by student test the observed symptoms and their intensity evaluated according to a severity score ranging from 0 to 4 are reported in the following tables table i__________________________________________________________________________evaluation of the symptoms in patients affected with venousinsufficiencyof the leg before and after a 3 months treatment with 1 5 esculoside patient nobefore 1 2 3.