this invention has been particularly shown and described with references to preferred embodiments thereof it will be understood by those skilled in the art that various changes in form and details may be made therein without departing from the spirit and scope of the invention as defined by the appended claims also sodium and potassium salts are considered equivalents of each other imaging techniques referred to herein are intended to include cat mri x rays and other possible imaging methods those skilled in the art will recognize or be able to ascertain using no more than routine experimentation many equivalents to the specific embodiments of the invention described specifically herein such equivalents are intended to be encompassed in the scope of the appended claims 1 battegay e j angiogenesis mechanistic insights neovascular diseases and therapeutic prospects j mol med 1995 73 333 346 2 o 39 reilly m s boehm t shing y fukai n vasios g lane w s flynn e birkhead j r olsen b r folkman j endostatin an endogenous inhibitor of angiogencsis and tumor growth cell 1997 88 277 285 3 sim b k o 39 reilly m s liang h fortier a h he w madsen j w lapcevich r nacy c a a recombinant human angiostatin protein inhibits experimental primary and metastatic cancer cancer res 1997 57 1329 1334 4 bicknell r harris a l mechanisms and therapeutic implications of angiogenesis curr opin oncol 1996 8 60 65 5 gately s twardowski p stack m s patrick m boggio l cundiff d l schnaper h w madison l volpert o 39 bouck n enghild j kwaan h c soff.