improving more than 8 points responders in the stimulation group was 18 as opposed to 7 in the sham group from the analysis of individual patient data it appears that those subjects with more severe cognitive dysfunction at baseline may have experienced more improvement from the active treatment than those with less severe cognitive dysfunction at baseline in the computerized mindstreams u2122 global cognitive score a significant p lt 0 05 difference was observed in the improvement of the group receiving the treatment relative to the changes measured in the sham control group in the 8 and 16 weeks time points reference is now made to fig1 which is an illustration of electric field distribution maps of coil 210 of fig7 the field distribution produced by coil 210 was measured using the same method as for fig9 the field maps are shown for stimulator output set at 120 of motor threshold it can be seen that when placing the base portion of the coil over the prefrontal cortex supra threshold field is induced bilaterally in lateral prefrontal medial prefrontal and orbitofrontal regions and in parietal regions reference is now made to fig1 which is an illustration of electric field distribution maps.