indole benzoate rizatriptan benzoate is indicated for the acute treatment of migraine attacks with our without aura in adults when rizatriptan benzoate is employed as the agonist in the compositions of the present invention it is present in an amount of from 5 to 10 mg corresponding to 7 265 mg or 14 53 mg of the benzoate salt respectively another agonist that can be employed in the composition of the present invention is eletriptan which after approval is obtained will be marketed by pfizer under the trademark relpax eletriptan is a selective serotonin 5 ht 1b 1d agonist that reproduces the action of a neuro transmitter in the brain called seratonin or 5ht which is believed to constrict swollen blood vessels in the membranes covering the brain and interrupt the transmission of pain serotonin 5 ht 1b 1d agonists activate sites in the swollen blood vessels u2014 called serotonin 1b and 1d receptors u2014 causing the vessels to constrict and reducing both the swelling and pain electriptan is described chemically as 5 2 benzenesulfonyl ethyl 3 1 methylpyrrolidin 2 r ylmethyl 1h indole when eletriptan is employed as the agonist in the compositions of the present invention it is present in an amount of from between 20 to 80 mg another 5 ht 1b 1d agonist that can be employed in the.