administered hgh the particles of the invention are employed in compositions suitable for drug delivery via the pulmonary system for example such compositions include the particles and a pharmaceutically acceptable carrier for administration to a patient preferably for administration via inhalation the particles can be co delivered with larger carrier particles not including a therapeutic agent the latter possessing mass median diameters for example in the range between about 50 u03bcm and about 100 u03bcm the particles can be administered alone or in any appropriate pharmaceutically acceptable carrier such as a liquid for example saline or a powder for administration to the respiratory system particles including a medicament for example one or more of the drugs listed above are administered to the respiratory tract of a patient in need of treatment prophylaxis or diagnosis administration of particles to the respiratory system can be by means such as known in the art for example particles are delivered from an inhalation device in a preferred embodiment particles are administered via a dry powder inhaler dpi metered dose inhalers mdi nebulizers or instillation techniques also can be employed the methods of the invention also relate to administering to the respiratory tract of a subject particles and or compositions comprising the particles of the invention which can be enclosed in a receptacle as described herein in certain embodiments the invention is drawn to methods of delivering the particles of the invention while in other embodiments the invention is drawn to methods of delivering respirable compositions comprising the particles of the invention as used herein the term u201c receptacle u201d includes but is not limited to for example a capsule blister film covered container well chamber and other suitable means of storing particles a powder.