by method of deferred antagonism for this the content of the bottle is dissolved in 1 ml of normal saline the received suspension is plated along the petri dish with agar medium gauze 2 plating is incubated in the thermostat at 37 u00b0 c during 72 hours then to the grown culture test microorganisms are streak plated 5000 mln suspensions of diurnal cultures in the normal saline the results are checked 18 hours later after incubation at 37 u00b0 c by the size of growth absence of test cultures growth control of test cultures is the parallel growth of them in plates with agar medium gauze 2 without studied culture data from the table 3 show that the optimal quantity of the alive cells in one dose of the preparation is 1 u2212 5 u00d7 10 9 the further increase of the microbe cells will not change significantly the antagonistic activity of the preparations regarding the test cultures of microorganisms to determine the therapeutical effect of the probiotic irilis received according to the examples 1 or 2 or 3 in comparison with the application of the preparation pectosorbin in the farm piglets with long term bad gastrointestinal diseases with the symptom complex of diarrhea form 3 groups of piglets of 1 2 days age with clinical sign of dyspepsia diarrhea liquefied stool dejecture had sour smell contained the gas bubbles loss of appetite dryness and paleness of the mucous tunics rapid pulse muffled heart sounds tachypnoe after clinical examination it was determined that 69 piglets have trivial dyspepsia and 12 piglets have toxical dyspepsia while conducting the bacteriological study of the samples of piglets 39 faeces in all ill piglets the pathogenic escherichia 10 8 10 11 bacteria in 1 g are detected in large quantities whereas the escherichia strains.