device and leaves the skin sampling side covered with the second liner this second liner protects the skin sampling adhesive area from sticking and from contamination until it is to be used when required for skin sampling the second liner is removed the tape can be applied onto any part of skin but the most suitable part is the surface of a palm because the palm does not have sebaceous glands whose secretions contain cholesterol which may affect results additionally the skin on the palm is readily accessible for sampling it is desirable to obtain uniform amounts of skin samples for analysis application of the adhesive tape for sampling is typically and routinely done using a single application of the tape to the skin additional amounts of stratum corneum material can be obtained by additional applications of the tape to the skin each subsequent application of the tape to the skin results in additional skin adhering to the tape this process continues until the tape becomes saturated with skin material after which it is no longer sticky the number of applications required to saturate a tape depends on the type of adhesive used but for the most commonly used adhesive tapes saturation is achieved with less than ten applications for example but not limited to three to seven applications applying tape to a fresh area of skin for each subsequent stripping results in better and faster saturation of the tape therefore for consistent and good sampling it is.