type in certain embodiments the present invention relates to the aforementioned method and any of the attendant limitations wherein the soluble factor is selected from the group consisting of bdnf cntf dvl 1 egf endostatin fgf gdnf gm csf heregulin igf il insulin interferon jagged1 m csf nag 1 ngf nt pdgf pedf prolactin sdf sf 1 tgf tnf vegf and wnt in certain embodiments the present invention relates to the aforementioned method and any of the attendant limitations wherein the soluble factor is selected from the group consisting of fibrinogen laminin collagen iv tenascin fibronectin collagen bovine pituitary extract egf hepatocyte growth factor keratinocyte growth factor hydrocortisone dimethyl sulphoxide recombinant human epidermal growth factor insulin sodium selenite transferrin hydrocortisone basic fibroblast growth factor and leukemia inhibitory factor in certain embodiments the present invention relates to the aforementioned method and any of the attendant limitations wherein the cells of a first type are mammalian cells in certain embodiments the present invention relates to the aforementioned method and any of the attendant limitations wherein the cells of a first type are human cells in certain embodiments the present invention relates to the aforementioned method and any of the attendant limitations wherein the cells of a first type are selected from the group consisting of cells of the anus bladder bile duct bone brain breast cervix colon rectum duodenum endometrium.