rutoside is 91 6 the solution containing trihydroxyethyl rutoside is passed through cation exchange resin 001x14 anion exchange resin 717 to remove salts then concentrated under reduced pressure and further spray dried with 9000 ml of methanol isopropanol 95 5 added the solid is heated to dissolve after active charcoal for refinement of injection is added the solution is heated at reflux for 30 min and filtered while hot the filtrate is let stand at room temperature for 6 h to allow crystallization after filtration the solid is dried at 40 50 u00b0 c and trihydroxyethyl rutoside is finally obtained in which the content of trihydroxyethyl rutoside is tested to be 91 7 the obtained solid was recrystallized from a 20 fold amount of methanol isopropanol 95 5 and dried the content of trihydroxyethyl rutoside is 92 4 trihydroxyethyl rutoside is prepared by the method disclosed in this invention after reaction the trihydroxyethyl rutoside in the reaction solution is purified by the following steps the solution containing trihydroxyethyl rutoside is passed through cation exchange resin 732 anion exchange resin 717 to remove salts then concentrated under reduced pressure and further spray dried with 8 000 ml methanol added the solid is heated to dissolve after active charcoal for refinement of injection is added and the solution is heated at reflux for 30 min filtered while hot the filtrate is then precipitated at room temperature for 6 h after filtration the solid is dried at 40 50 u00b0 c and trihydroxyethyl rutoside is finally obtained in which the content of trihydroxyethyl rutoside is tested to be 92 4 the obtained solid was recrystallized from a 20 fold amount of methanol and dried the content of.