narcotic requirements should be less and recovery should improve cefuroxime zinacef 750 mg prepared in 10 cc normal saline 0 9 u2014 this additive is not expected to improve pain after infiltration but is expected to decrease the chances of infection this is done in conjunction with the standard peri operative intravenous antibiotic prophylaxis and antibiotic irrigation solution cefuroxime is in a similar class of antibiotics used for intravenous antibiotic prophylaxis usually cefazolin u2014 ancef kefzol the following mixture of agent is then combined under sterile procedures in a normal saline solution for a total volume of 60 cc this mixture is injected by needle in a manner never before described in the medical literature into the soft tissues around the hip and knee whereas other fda approved local delivery systems currently available focus on the intra articular release of anesthetic agents this system relies on the soft tissue penetration of these agents to gradually elute their effects moreover by concentrating the agents in the soft tissues which elicit the greatest pain response the effect on recovery of function is enhanced after stable joint reconstruction with trial implants is achieved the trials are removed and the wound is copiously irrigated removal of the implants allows for increased access to the peri articular soft tissues particularly the posterior capsule for the knee and the anterior capsule for the hip using proper injection technique aspiration prior to injection.