and 7 2 6 2 4 summarize the results of the analyses performed on the pharmacokinetic parameters for dose adjusted sildenafil 1 spray 10 mg versus reference product d 25 mg n 24 treatment a sildenafil citrate oral spray 11 55 w w 1 spray equivalent to 10 mg sildenafil 2 sprays 20 mg versus reference product d 25 mg n 23 treatment b sildenafil citrate oral spray 11 55 w w 2 sprays equivalent to 20 mg sildenafil 3 sprays 30 mg versus reference product d 25 mg n 24 treatment c sildenafil citrate oral spray 11 55 w w 3 sprays equivalent to 30 mg sildenafil when pk parameters auc and c max for oral spray products test a 10 mg test b 20 mg and test c 30 mg were dose adjusted to the reference d tablet 25 mg the relative bioavailability of sildenafil in the test oral spray products as compared to the reference tablet product demonstrated that the dose adjusted c max values of sildenafil for the 10 mg 20 mg and 30 mg oral spray products were comparable to the reference d product 25 mg tablet and all were within the 90 ci the test reference ratio point estimates for the dose adjusted auc 0 inf for all the sildenafil oral spray doses were approximately 114 to 121 the upper limit of the 90 ci was 124 for test a 10 mg and test c 30 mg.