to 10 most preferably the iodophor is polyvinylpyrrolidone iodine most advantageously the bone is cleaned with a detergent solution under high pressure washing conditions at elevated temperatures high pressure washing conditions should provide a force sufficient to drive the cleaning solution into internal matrix of the bone such high pressure washing conditions include for example vigorous agitation such as with a paint can shaker or high pressure lavage such as with a high pressure liquid jet stream suitable paint can shakers are those manufactured by red devil preferably model 0 5400 0m 615 rpm and 0 25 horsepower the pressure of the liquid jet stream is preferably 100 to 3 000 psi and most preferably 500 to 1 500 psi most preferably the liquid jet stream is sterile and includes detergent cleaning is accelerated significantly and is more thorough if effected at temperatures within the range of 0 u00b0 to 80 u00b0 c preferably 37 u00b0 to 80 u00b0 c most preferably high pressure washing effectively loosens marrow and progressively removes debris within the cancellous bone matrix following this high pressure washing procedure the bone is strikingly cleaner and whiter than bone processed by standard methods see fig1 to expedite cleaning the solution may be changed for example by transferring the bone to fresh solution during the cleaning operation preferably the solution is changed at least two times after cleaning detergent.