found c 66 77 h 8 62 n 2 90 to a solution of the title compound of example 59 18 mg in dichloromethane 0 5 ml was added triethylamine 0 007 ml 4 dimethylaminopyridine 0 1 mg and toluenesulfonyl chloride 8 0 mg the mixture was stirred at ambient temperature for 5 hours additional toluenesulfonyl chloride 0 5 mg was added and stirring was continued another 16 hours concentration followed by chromatography afforded the title compound 8 1 mg the nmr was identical to that of example 15 the title compound of example 15 76 mg 0 16 mm was diluted with dichloromethane 1 ml triethylamine 0 07 ml 0 5 mm and 4 dimethylaminopyridine 0 1 mg were added followed by acetic anhydride 0 046 ml 0 48 mm after stirring the solution for 4 hours at ambient temperature the solvent was removed by rotary evaporation and the residue was purified by silica gel chromatography to afford the title compound as a solid 82 mg mass spectrum m e 560 m nmr 400 mh z cdcl 3 7 63 m 2h 7 59 m 2h 7 42 m 2h 7 37 m 4h 4 97 m 1h 4 93 m 1h 3 92 m 1h 3 68 dd 1h j 1 12 hz j 2 4 0 hz 3 65 dd 1h j 1 12 hz j 2 2 0 hz 3 25 dd 1h j 1 12 hz j 2 4.