g peo pbo peo and reverse triblocks such as pbo peo pbo copolymers the copolymers are generally used in embodiments of the present invention at a concentration of 0 001 to 1 0 w v and preferably at a concentration of 0 001 to 0 1 w v certain embodiments of the present invention are ophthalmic compositions comprising hydrogen peroxide and a boron compound that are substantially free of surfactants these substantially surfactant free embodiments demonstrate advantageous and unexpected behavior relative to neutralization kinetics as shown by the data presented below in example 4 below surfactant free peroxide formulations of the present invention may neutralize at a slower rate than those formulations containing surfactants and accordingly retain a higher concentration of hydrogen peroxide during the neutralization process and the attendant antimicrobial advantages also surfactant free embodiments may also demonstrate unexpected and advantageous cleaning properties as shown by the lysozyme cleaning data presented in example 5 below the ophthalmic compositions of the present invention may comprise one or more additional preservatives disinfecting or antimicrobial agents examples of such preservatives and agents include but are not limited to benzalkonium chloride sodium perborate sodium chlorite guanidine derivatives such as polyhexamethylene biguanide and quaternary ammonium salts in certain embodiments the composition may be self preserved that no preservation agent is required the compositions of the present invention are preferably isotonic or slightly hypotonic this may require a tonicity agent to bring the osmolality of the compositions to a level at or near 210 320 milliosmoles per kilogram mosm kg the compositions of the present invention generally have an osmolality in the range of 210 320 mosm kg and preferably have an osmolality in the range of 220 300 mosm kg the ophthalmic compositions will generally be formulated.