5 07 s 2h 3 94 m 1h 3 68 s 2h 3 43 s 2h 2 78 2 72 m 4h 2 57 2 55 m 2h 1 77 d j 1 6 hz 3h esims 446 2 m h the following compounds can be prepared by following the general scheme 1 and the process described in example 1 above including their suitable modifications well within the scope of a skilled person 1 h nmr dmso d 6 400 mhz u03b4 7 44 s 1h 7 35 7 28 m 7h 6 98 d j 8 8 hz 2h 6 09 s 2h 4 27 dd j 6 4 8 4 hz 1h 3 86 s 2h 3 57 s 4h 2 53 2 41 m 1h 2 33 2 32 m 1h 1 h nmr cdcl 3 400 mhz u2014 7 47 d j 5 2 hz 1h 7 37 7 23 m 6h 7 11 d j 5 2 hz 1h 6 92 d j 8 8 hz 2h 5 06 s 2h 4 77 4 68 m 2h 4 19 t j 7 6 hz 1h 3 55 t j 6 8 hz 2h 3 06 2 98 m 3h 2 88 2 82 m 1h 1 h nmr cd 3 od 400 mhz u03b4 7 48 s 1h 7 39 7 36 m 3h 7 31 dd 2 6 8 hz 2h 6 98 dd j 2 4 6 8 hz 2h 5 10 s 2h 4 3 u2212 4 26 m 1h 4 18 t j 5 2 hz 2h 3 89 s 2h 3 83 s 2h 2 97 t j 5 6 hz 2h 2 74 dd.