tool spotfire other ways for visualizing similarity measures can be sued as well methods for determining co occurrence frequency information for object associated observations in data bases are known to those skilled in the art one particular method is the natural language processing tool medlee but other ways for obtaining co occurrence frequency information can be used as well any of the previous methods may be used for determining cause effect relationship of medicines any of the previous methods may be used for determining biological equivalence between prescription medicines and remedies used in traditional medicines or between prescription medicines and pharmacologically active substances isolated from animal or plant origin any of the previous methods can also be used for identifying new indications or side effects of medicines and new indications or side effects of combination of medicines any of the previous methods can also be used for identifying new indications or side effects of remedies used in traditional medicine any of the previous methods can also be used for identifying new indications or side effects of pharmacologically active substances isolated from animal plant or microorganism origin these methods can also be used for identifying biomarkers associated with disease these methods can also be used for identifying biomarkers associated with.