degradation of the implant material deduction of total mass of the implant and generation of rich capillary networks in the interface of old and new tissues no neutrophil lymphocyte or other cell reaction for inflammation is found and no cyst wall is formed the arachnoid mater and brain tissue are normal while the results with the control show that the implant material is not yet degraded and at the implanted site the inner surface of meninges adheres to brain tissue to some degree the dura mater obtained from example 6 is now applied to the dog experiment and the method is the same as experimental example 2 twelve months post implantation the dogs are sacrificed and the specimen is taken at the surgical site the specimen includes the artificial dura mater surrounding dura mater and part of the surrounding brain tissue when observe the specimen carefully it is seen that the connection between the artificial dura mater and native dura mater is tight and smooth without clear boundary completed cured and with thread seen only the native dura mater does not show hyperaemia hemorrhage or other rejection reaction the dura mater obtained from example 7 is now applied to the new zealand rabbit experiment the method is the same as experimental example 3 twelve months post implantation the rabbits are sacrificed and the specimen is taken at the surgical site when observe the specimen carefully it is seen that the epithelial cells cover.