as caffeine the preferred solubilizing agent is polyvinylpyrrolidone macrogol polyvinyl alcohol benzoic acid sorbic acid and alginic acid and polyvinylpyrrolidone is especially preferable these solubilizing agents can be used alone or as a combination of any two or more the molecular weight of the polyvinylpyrrolidone used herein is preferably 200000 or less and more preferably 40000 or less the preferred polyvinylpyrrolidones includes but is not limited to polyvinylpyrrolidone pvp purchased from basf kollidon 25 pvp k 25 polyvinylpyrrolidone pvp purchased from basf kollidon 17pf pvp k 17pf the ratio of rebamipide versus polyvinylpyrrolidone is preferably 20 1 to 1 20 more preferably 4 1 to 1 6 and even more preferably 1 1 to 1 2 when a solubilizing agent is added the concentration of the solubilizing agent is generally in a range of about 0 01 to about 15 w v preferably about 0 1 to about 10 w v more preferably about 0 5 to about 6 w v and even more preferably about 1 to about 5 w v or about 2 to about 4 w v the zinc compounds used herein are for example zinc chloride and zinc sulfate and zinc chloride is preferred these zinc compounds can be used alone or as a combination of any two or more the amount of zinc in the zinc compound in the present pharmaceutical composition is about 0 0000005 to about 0 000025 times preferably about 0 0000005 to about 0 00001 times more preferably 0 0000005 to about 0 000005 times and even.