the compounds are well suited to formulation as sustained release dosage forms and the like the formulations can be so constituted that they release the active ingredient only or preferably in a particular part of the intestinal tract possibly over a period of time the coatings envelopes and protective matrices may be made for example from polymeric substances or waxes the particular dosage of a compound of formula i according to this invention will depend upon the severity of the condition the route of administration and related factors that will be decided by the attending physician generally accepted and effective daily doses will be from about 0 1 to about 1000 mg day and more typically from about 50 to about 200 mg day such dosages will be administered to a subject in need of treatment from once to about three times each day or more often as needed it is usually preferred to administer a compound of formula i in the form of an acid addition salt as is customary in the administration of pharmaceuticals bearing a basic group such as the piperidino ring for such purposes the following dosage forms are available in the formulations which follow 34 active ingredient 34 means a compound of formula i ______________________________________formulation 1 gelatin capsuleshard gelatin capsules are prepared using the following ingredient quantity mg capsule ______________________________________active ingredient 0 1 1000starch nf 0 650starch flowable powder 0 650silicone fluid 350 centistokes 0 15______________________________________ the ingredients are blended passed through a no 45 mesh u s sieve and filled into.