his vector invitrogen which is described in the literature gentz et al proc natl acad sci usa 1989 86 821 824 further this polynucleotide may comprise a 5 u2032 and 3 u2032 noncoding sequence for example transcribed but non translated sequences splicing and polyadenylation signals ribosome binding sites and mrna stabilization sequences the present invention provides nucleotides having a chain length of at least 15 nucleotides which are complementary to a polynucleotide isolated by the present inventors a polynucleotide or a complementary strand thereof consisting of the nucleotide sequences of odd numbered seq id nos from seq id no 1 to seq id no 2069 herein the term u201c complementary strand u201d is defined as one strand of a double strand nucleic acid composed of a t a u in case of rna and g c base pairs to the other strand also u201c complementary u201d is defined as not only those completely matching within a continuous region of at least 15 sequential nucleotides but also those having a homology of at least 70 preferably at least 80 more preferably 90 and most preferably 95 or higher within that region the homology may be determined using the algorithm described herein probe and primers for detection or amplification of the polynucleotides of the present invention are included in these polynucleotides typical polynucleotides used as primers have a chain length of 15 to 100 nucleotides and preferably 15 to 35 nucleotides alternatively polynucleotides used as probes are nucleotides having a chain length of at least 15 nucleotides preferably at least 30 nucleotides containing at least a portion or the whole sequence of a dna of the present invention such nucleotides preferably hybridize specifically to a dna encoding a polypeptide of the present invention the term u201c.