bacteria fungi protozoa and viruses in vitro in general to reduce microorganisms on skin and prevent infections in skin topical solutions containing between about 1 and 15 pvp iodine 0 1 and 1 5 available iodine may be used it is preferred that the solution contain between about 5 and 10 pvp iodine 0 5 and 1 available iodine and most preferably the solution contain about 10 pvp iodine 1 available iodine anticipating the dilution with water upon wetting prior to use the initial concentration of pvp iodine in the manufactured anhydrous solution could contain higher concentration of pvp iodine the substrate comprises synthetic woven non woven or knitted fibers or blends thereof the intended use hands body first aid dictates the amount of add on needed to achieve effective skin antisepsis the treatment solution may also contain from about 0 5 to 40 non ionic or cationic surfactant and preferably about 5 to about 15 in the case where an amphoteric is the sole surfactant it is present in larger amounts up to and including about 50 and preferably 10 to 50 the specific amount of the particular non ionic or cationic surfactant which is employed within this range will depend upon the detergent activity desired as can be readily determined by one of ordinary skill in the art any of.