5 m 18 10 sup 6 m 26 ns 78 6cl h ch sub 3 nhco sub 2 c sub 2 h sub 5 14 5 10 sup 5 m 24 5 ns 346cl h ch sub 3 nhco sub 2 ch sub 3 64 5 10 sup 5 m 25 24 53 26 6 10 sup 6 m 86 1 55 817cl ch sub 3 nhco sub 2 ch sub 3 50 10 sup 5 m 24 3 ns 28 17 10 sup 6 m h h ch sub 3 nhco sub 2 ch sub 3 61 10 sup 5 m 26 8 ns 21 2 11 10 sup m 85 0 37 2 58 6__________________________________________________________________________ ns not significant the isoquinoline acetic acids and acetyl carbamates were prepared by the following reaction scheme str10 wherein r 1 and r 2 are hydrogen halogen r 3 is alkyl or aralkyl r 5 is hydroxy or alkyl carbamate r 7 is methyl or ethyl and x y are oxygen the process for the production of the compounds of formula i wherein r 1 and r 2 are halogen fluorine chlorine or hydrogen r 3 is alkyl methyl or aralkyl 4 bromo 2 fluorobenzyl r 4 is hydrogen r 5 is hydroxy or alkyl methyl ethyl carbamate x y are oxygen comprises reacting either homophthalic acid dimethyl ester of formula v or homophthalic anhydride of formula vi wherein r 1 and r 2 are as defined above with an amine r 3 nh 2 wherein r 3 is as defined above to produce the homophthalimide of formula vii wherein r 1 r 2 and r 3 are as defined above the homophtalic acid dimethyl esters of formula v and the homophthalic anhydrides of formula vi.