means a compound having formula r 6 c o cl wherein r 6 is phenyl or naphthyl each of which is unsubstituted or substituted with one or two or three of independently selected och 3 och 2 ch 3 f cl or br the effect of the solubility of compounds having formula vii wherein r 4 is ethyl and r 6 is variable in ethyl acetate is shown in the term u201c chlorinating agent u201d as used herein means n chlorosuccinimide thionyl chloride cl 2 cl 2 o and the like with or without water and with or without an acid such as sulfuric acid phosphoric acid trifluoroacetic acid perchloric acid and the like the yields of chlorinations of compounds having formula vii wherein r 4 is ch 2 ch 3 and r 5 is c o r 6 wherein r 6 is ch ch 3 2 with n chlorosuccinimide in ethyl acetate is shown in the term u201c hydrogenolysis catalyst u201d as used herein means water wet or not water wet 5 palladium hydroxide water wet or not water wet 10 palladium hydroxide water wet or not water wet 5 palladium hydroxide on carbon water wet or not water wet 10 palladium hydroxide on carbon and the like or mixtures thereof the term u201c hydroxide base u201d as used herein means the hydroxide base of sodium potassium lithium barium and the like or mixtures thereof the term u201c non protic acid u201d as used herein means lithium chloride magnesium chloride.