25 g mol 0 755 g cm 3 0 1 mmol and dry dmf 2 1 ml for 30 minutes resin was then filtered and washed twice with dmf twice with meoh once with dcm and once with thf fmoc protection of the phenylalanine was removed according to procedure described in step i but without any washes prior treatment with piperidine dmf fmoc dbu boc oh 211 3 mg 440 5 g mol 0 47 mmol 3 eq was coupled to resin bound compound using same coupling agents and procedure as described in step ii possibly unreacted amino groups were acetylated using the procedure described in step iii fmoc protection of the amino acid attached in step v was removed according to procedure described in step i but without any washes prior treatment with piperidine dmf 4 methyl 1 naphthalenesulfonyl chloride 115 mg 240 71 g mol 0 47 mmol 3 eq maybridge was dissolved in dry thf 2 5 ml mixed with the resin and tea 65 u03bcl 101 19 g mol 0 73 g cm 3 0 47 mmol 3 eq baker was added to the mixture after overnight agitation solvent was filtered and resin washed thrice with thf twice with meoh twice with dmf once with meoh and finally thrice with dcm resin 0 16 mmol was swollen with dry dmf 2 5 ml and dbu 240 u03bcl 152 24 g mol 1 018 g cm 3 1 6 mmol 10 eq acros was added to the mixture methyl iodide 1 6 mmol 141 94 g mol 2 28 g cm 3 1 6 mmol 10 eq acros was then added dropwise to the mixture after overnight agitation solvent was filtered and resin washed twice with dmf twice.