adjusted for focus step 57 for example by a methodology such as described at fig1 in fig1 there is shown a method for adjusting low magnification focus first there is a determination of whether the low magnification field is the first low magnification field in the sequence order step 232 if the low magnification field is the first low magnification field in the sequence order at step 236 the z range at the low magnification field is recalculated by interpolation using database s incorporating z focus range found from the u201c find focus on slide edge u201d 233 and z difference from the top edge to bottom edge 234 if possible if not step 237 there is termination step 186 if the low magnification field is not the first low magnification field in the sequence order then the neighborhood of potential structures of interest is set to a defined number step 239 and each neighborhood is inquired in low magnification step 241 to determine if there is one or more neighborhoods with a valid z focus value step 244 and if so the average of all the z focus values is taken step 247 and if not the number or size of neighborhoods are expanded step 243 until there are no more neighbors to expand 243 and a flag 237 is sent to complete 186 the string returning back.