include plural referents unless the context clearly dictates otherwise thus for example reference to u201c a terpenoid u201d includes a plurality of such terpenoids and reference to u201c a lipoxygenase inhibitor u201d includes reference to one or more lipoxygenase inhibitors and equivalents thereof known to those skilled in the art and so forth the publications discussed herein are provided solely for their disclosure prior to the filing date of the present application nothing herein is to be construed as an admission that the present invention is not entitled to antedate such publication by virtue of prior invention further the dates of publication provided may be different from the actual publication dates which may need to be independently confirmed the invention disclosed herein provides pharmaceutical compositions comprising terpene or terpenoid compounds found in the sponges suberea sp cacospongia sp jaspis sp igernella sp coscinoderma sp hippospongia sp dictyodendrilla sp heteronema sp or of the family halichondriidae and other sponge or natural sources or synthetic derivatives thereof which exhibit lipoxygenase inhibition activity or are efficacious in the treatment of lipoxygenase mediated conditions or are effective at promoting or improving cell viability or preventing cell damage in various tissues or organs under ischemic anoxic or hypoxic conditions the invention also provides methods for inhibiting lipoxygenase comprising contacting or exposing a lipoxygenase to an effective amount of one or more of the subject compounds the invention further provides methods for treating a subject suffering from a lipoxygenase mediated condition comprising administering to the subject a therapeutically effective amount of one or more of the subject compounds the invention additionally provides methods for preventing cell damage and or increasing cell viability in various tissues and.