g of dermatansulfate sodium salt having molecular weight of about 7000 dalton are solubilized in 200 ml of distilled water the solution is eluted in a column cooled at 40c containing 120 ml of cationic exchange resine dowex u00ae 50 u00d7 8 generated in li form the eluate free from sodium is frozen and lyophilized the reaction yield is 23 3 g ______________________________________physical state white amorphous powderraw formula c sub 14 h sub 19 no sub 14 sli sub 2molecular weight 7000 daltonelemental analysis c 35 68 h 4 06 n 2 97 s 6 80 li 2 95 calculated c 35 55 h 4 10 n 2 92 s 6 80 li 2 90 found water solubility gt 10 mg ml______________________________________ ______________________________________2 a gel formulation______________________________________n n bis 2 hydroxyethyl nonandiamide 2 dermatansulfate lithium salt 0 10 hydrated lithium solution 5 1 8 o phenylphenol 0 20 p methyl hydroxybenzoate 0 10 p ethyl hydroxybenzoate 0 10 carbomer 0 70 dem water 95 ______________________________________ a the gelold base is prepared water and carbomer 940 under vacuum maintaining a good agitation until carbomer is completely swelled and homogenized b the different active principles are added gradually stirring until complete dissolution and homogeneization c once completed the addition of the different active principles agitation is continued for further 30 60 minutes restoring from time to time the vacuum and afterwards the liquid is drained into the containers provided for this purpose the gel obtained in this manner is characterized by a medium consistence opalescent aspect a light aromatic smell and ph 6 5 u00b1 0 5 viscosity is about 2800 cps determined with viscometer contraves u00ae mod tv 3 200 rot min rotor at 20 u00b0 c density is about 1 0030 determined with pycnometer suitable for measuring pasty.