added to the heated slurry over 20 min 1 g h2 2 dihydrate seeds was added upon completion of the ethanol addition xrd samples were periodically monitored for transformation of h2 1 dihydrate to h2 2 dihydrate the slurry was cooled to 2 u00b0 c over 2 hours after pure h2 2 dihydrate was obtained 4 to 10 hours the reaction slurry was held at 2 u00b0 c for at least u00bd hour before filtration the cold slurry was filtered employing a buchner funnel and filter paper whatman 4 the cake was washed with u02dc 2 cake volume of ethanol water 1 2 and u02dc 4 cake volume of water the resulting wet cake was suction dried 118 g of h2 2 dihydrate was obtained yield 92 2 particle size d95 25 u03bcm observed and simulated powder x ray diffraction patterns and thermogravimetric analysis thermograms of the h2 2 dihydrate crystals produced in example 5 are shown in fig3 and 4 and 4 a respectively an oral solution of the following composition was prepared as described below ingredients vehicle amount w w d alpha tocopheryl polyethylene glycol 1000 20 succinate tpgs polyoxyethylene 20 sorbitan monooleate tween 80 8 5 or polysorbate 80 95 ethanol usp 10 polyethylene glycol.