equivalent if they deliver the same total quantity of drug and at the same rate duration of delivery the total drug delivered is take at the plateau regions of fig1 and is determined to be 7 66 mg for control and 6 935 mg and 6 811 mg for test samples on a percentage basis the test samples are within 11 of the control this is remarkable in that the total drug loading for the devices is 10 mg but only a consistent fraction of this is released as some remains trapped within the matrix the test samples that underwent mechanical and thermal stress did not provide a total dose meaningfully different than the control these results attest to the surprising robustness of the drug delivery matrix under the conditions of high drug loading severe mechanical and thermal stress including balloon distention these findings are even more significant inasmuch as the amount of drug loading was so high that it exceeded typical therapeutic levels balloon expandable stent having interstices coated with tfe ppve to form a stent graft a sample of tfe ppve copolymer described by example 9 was prepared the polymer was dissolved in fc 75 to obtain a 20 wt solution the working formulation was made by diluting 2 ml of the 20 wt polymer solution with 8 ml of fc 75 and.