the effective dosage range and the decision as to the exact dosage used must be made by the administering physician based on his judgement of the patient 39 s general physical condition in determining the dose for the individual patient the physician may begin with an initial dose of 0 25 g square meter of body surface to determine how well the drug is tolerated and increase the dosage with each succeeding radiation treatment observing the patient carefully for any drug side effect the composition to be administered is an effective amount of the active compound and a pharmaceutical carrier for said active compound the dosage form for intravenous administration is a sterile isotonic solution of the drug oral dosage forms such as tablets capsules or elixirs may also be used capsules or tablets containing 25 50 100 or 500 mg of drug capsule or tablets are satisfactory for use in the method of treatment of our invention the following examples are intended to illustrate but do not limit the process of preparation product compositions or method of treatment aspects of the invention temperatures are in degrees celsius unless otherwise indicated throughout the application part a examples of compounds in which at least one of r 2 and r 3 is a basic substituent a mixture of 2 amino 6 nitrobenzoic acid 11 9 g 65 3 mmol methyl p toluenesulfonate 15 1 g 81 1 mmol and triethylamine 6 60 g 65 3 mmol in dmf 170 ml was.