as preservatives stabilizers emulsifiers flavor improvers wetting agents buffers salts for varying the osmotic pressure and the like solid carrier material which can be used include for example starch lactose mannitol methyl cellulose microcrystalline cellulose talc silica dibasic calcium phosphate and high molecular weight polymers such as polyethylene glycol for parenteral use a compound of formula i can be administered in an aqueous or non aqueous solution suspension or emulsion in a pharmaceutically acceptable oil or a mixture of liquids which may contain bacteriostatic agents antioxidants preservatives buffers or other solutes to render the solution isotonic with the blood thickening agents suspending agents or other pharmaceutically acceptable additives additives of this type include for example tartrate citrate and acetate buffers ethanol propylene glycol polyethylene glycol complex formers such as edta antioxidants such as sodium bisulfite sodium metabisulfite and ascorbic acid high molecular weight polymers such as liquid polyethylene oxides for viscosity regulation and polyethylene derivatives of sorbitol anhydrides preservatives may also be added if necessary such as benzoic acid methyl or propyl paraben benzalkonium chloride and other quaternary ammonium compounds the compounds of this invention may also be administered as solutions for nasal application and may contain in addition to the compounds of this invention suitable buffers tonicity adjusters microbial preservatives antioxidants and viscosity increasing agents in an aqueous vehicle examples of agents used to increase viscosity are polyvinyl alcohol cellulose derivatives polyvinylpyrrolidone polysorbates or glycerin microbial preservatives added may include benzalkonium chloride thimerosal chloro butanol or phenylethyl alcohol additionally the compounds provided by the invention can be administered topically or by suppository compounds of the formula i can be formulated for therapeutic administration in a number of ways.