fibroblast to the next and are believed to be effective for blocking conduction the invention according to the highly beneficial embodiments described herein provides systems and methods to treat atrial fibrillation using fibroblast cell transplantation in one particular highly beneficial embodiment the fibroblasts are taken from dermal samples of the patient being treated and are subsequently prepared appropriately that is isolated and amplified e g in a culture preparation kit and transplanted to or around a patient 39 s av node the invention therefore according to one beneficial embodiment uses autologous fibroblasts from the patient 39 s own body and transplants them to the av node area fibroblasts are cells that can survive and multiply in a low oxygen environment and have the ability to block or change remodel modify a conduction pathway therefore according to certain particular embodiments of the present invention a patient 39 s own fibroblasts are cultured and transplanted into the patient 39 s av node where they can proliferate and act as a blocking agent to treat atrial fibrillation fibroblasts are a cell line that typically is associated with tissue damage i e skin damage ami and healing of tissue to produce scar tissue activation of fibroblasts occurs in response to injury these events cause a transition of cell types.