267 5 186 938 5 573 778 5 252 334 and 5 780 050 a removable liner sheet 110 covers the active agent containing layer 120 and is attached to the adhesive layer 140 the selection of the removable release liner 110 is dependent on the type of the adhesive in use and is well known to a person skilled in the art the release liner 110 is typically a polymer sheet or a paper coated with a polymer which have rather weak adhesion toward the adhesive layer 140 therefore allowing itself being easily removed prior to use without damaging the adhesive layer 140 in addition to or in lieu of the adhesive 140 the apparatus 500 may be fastened to the body surface with an adhesive tape an elastic band a band with a buckle similar to a leather watch band or a velcro band or the like alternatively the active agent unit 100 may be a transdermal patch such as one of those transdermal active agent delivery devices currently in the market the examples include transdermal patches of fentanyl duragesic u00ae by janssen pharmaceutical nitroglycerin nitrodisc u00ae by roberts pharmaceutical g d searle nitro dur u00ae by schering key pharmaceutical and transderm nitro u00ae by ciba geneva and minitran u00ae by 3m riker 17 u03b2 estradiol estraderm u00ae by ciba geneva clonidine catapres u00ae tts by boehringer ingelheim testosterone testoderm u00ae by alza and androderm u00ae by smithkline beecham scopolamine transderm scop u00ae by ciba geigy nicotine nicoderm u00ae by marion merrell dow habitrol u00ae by ciba geigy nicotrol u00ae by mcneil consumer.