drug bed 110 of 1000 mg utilizes a housing 37 0 75 inches in internal diameter and a height of 1 25 inches the internal volume of this housing 37 is roughly 9 milliliters for appropriate delivery this drug is administered over a period of 40 minutes forming a total of 60 milliliters of solution at concentration between 10 and 40 milligrams milliliter the interior of the housing 37 is divided into two chambers the upper chamber contains the compression component 85 the core and the reagent for exemplary 1000 mg dose of drug the dry volume is 3 0 milliliters the preferred compression component has a height of 0 875 inches the central cavity 90 within this component 85 has an interior diameter of 0 25 inches to accommodate the core 105 the preferred component 85 has a preferred porosity of about 60 to 90 pores per inch ppi more preferably 75 ppi and a preferred compression load deflection cld of about 0 4 to 0 6 psi at 25 compression more preferably 0 5 psi at this compression at 65 compression the cld is preferably about 0 5 to 0 8 psi more preferably 0 65 psi these cld were determined by measurement of deflection 50 square inches of material it is compressed within the housing to fill the area upstream of the reagent bed the exemplary core 105 has a height of 0 675 inches and an outer diameter of 0 225 inches.