coating layer on the dissolution profile of complex tablets the release profiles of the above complex systems were tested using a dissolution apparatus with paddles at 100 rpm using 500 ml of a ph 1 2 solution for the first two hours and 1000 ml of phosphate buffer solution for the rest of the test total duration 24 h the results of the dissolution tests performed for the most typical of the above systems are presented in the following tables 16 20 the above results show that the said complex systems can be applied with great flexibility and cause an extensive reduction of the initial drug release this reduction ranges from 2 to 13 5 while the duration of the function of the coating layer can also be controlled and manipulated the following examples of the coating films are applied on the core described in example 2 1 as a model core so that the effect of the coating film on the formulation can be evaluated the 75 mg core was enabled as a worst case as it is the core with the biggest surface manufacturing process the constituents of the coating film are dispersed in the solvent mixture preparing a homogeneous dispersion of 5 15 solid content then the coating film is spray coated on the cores that were.