acidic basic or neutral charcoal column chromatography on a column packed with a chiral stationary phase filtration through a porous paper plastic or glass barrier column chromatography on silica gel ion exchange chromatography recrystallization normal phase high performance liquid chromatography reverse phase high performance liquid chromatography trituration and the like the term u201c miscible u201d as used herein means capable of combining without separation of phases the term u201c solvate u201d as used herein means having on a surface in a lattice or on a surface and in a lattice a solvent such as water acetic acid acetone acetonitrile benzene chloroform carbon tetrachloride dichloromethane dimethylsulfoxide 1 4 dioxane ethanol ethyl acetate butanol tert butanol n n dimethylacetamide n n dimethylformamide formamide formic acid heptane hexane isopropanol methanol methyl ethyl ketone 1 methyl 2 pyrrolidinone mesitylene nitromethane polyethylene glycol propanol 2 propanone pyridine tetrahydrofuran toluene xylene mixtures thereof and the like a specific example of a solvate is a hydrate wherein the solvent on the surface in the lattice or on the surface and in the lattice is water hydrates may or may not have solvents other than water on the surface in the lattice or on the surface and in the lattice of a substance the term u201c solvent u201d as used herein means a substance typically a liquid that is capable of completely or partially dissolving another substance typically a solid solvents for the practice of this invention include water acetic acid acetone acetonitrile benzene chloroform carbon tetrachloride dichloromethane dimethylsulfoxide 1 4 dioxane ethanol ethyl acetate.