tube 26 is retracted the spool valve 46 is in the first position with the vacuum lumen 30 vented to atmosphere via central port 118 and distal port 122 the retraction of the cutter gear 92 causes the shuttle 154 to retract correspondingly with its downward lug 152 moving within the delay slot 158 of the distal actuating portion 132 of the valve control rod 130 once the carriage 150 of the reusable handpiece 12 reaches full proximal travel the lug 157 contacts the proximal end of the delay slot 158 and changes the pneumatic sequencing spool valve 46 from the first position to the second position thus the vacuum lumen 30 is also exposed to vacuum via central and proximal ports 118 120 of the spool valve 46 that communicates via the needle vacuum line 38 to the replaceable container 18 exposing the suspicious lesion to the vacuum assistance from both lines 38 40 to prolapse tissue into the side aperture 20 the spool valve 46 stays in this configuration as the cutter tube 26 is advanced distally while rotating to sever the tissue sample 19 as the shuttle 154 approaches its distal most position the lug 157 contacts the distal end of the delay slot 158 of the distal actuating portion 132 of the.