considerable degradation the pharmaceutical formulation of the invention may furthermore comprise salts for adjusting the tonicity and or an excipient in order to facilitate the processing thereof e g lyophilization and the rapid and complete dissolution of a lyophilized formulation when reconstituting the formulation before use an excipient may be selected from disaccharides such as lactose trehalose and sucrose sugar alcohols such as sorbitol or mannitol polysaccharides such as the polymers commercialized as dextran u00ae products such as dextran u00ae 40 dextran u00ae 70 or dextran u00ae 75 and ficoll u00ae and polyvalent alcohols such as polyethylene glycol or polyvinyl alcohol or a combination of two or more of these the pharmaceutical formulation may be prepared by adding growth hormone to a solution comprising leucine preferably in an amount of up to 100 mm more preferred in an amount of about 1 10 mm preferably 2 6 mm most preferred about 3 5 mm the growth hormone may be in solid form or may be in a buffer solution e g histidine citrate tartrate or phosphate buffer the leucine solution may be obtained by dissolving leucine in deionized water optionally containing of benzyl alcohol the ph of said formulation may be adjusted from.