81 s 3h 1 h nmr cdcl 3 u03b47 36 d 2h j 8 8 hz 6 88 d 2h j 8 8 hz 6 27 d 1h j 1 0 hz 5 83 d 2h j 1 1 hz 3 82 s 6h to a 0 u00b0 c solution of 0 50 g of 6 methoxy 2 naphthol in 1 4 ml of dry pyridine is added 0 49 ml of triflic anhydride the reaction is allowed to warm to room temperature and stirred for 24 hours the mixture is poured into a solution of 50 ml of water and 50 ml of diethyl ether the aqueous layer is extracted three times with diethyl ether and the combined organic layers are dried filtered and concentrated in vacuo the residue is purified by chromatography silica gel ethyl acetate hexane to give 0 67 g 76 yield of the desired product as a colorless oil to a room temperature solution of 0 306 g of product from example 9 in 10 ml of dimethylformamide is added 0 938 g of 2 tributylstannyl 2 propenoic acid methyl ester 0 116 g of tetrakis triphenylphosphine palladium 0 0 143 g of copper 1 iodide and 0 128 g of lithium chloride the resulting reaction mixture is stirred at room temperature for 48 hours and then poured into 100 ml of diethyl ether the layers are separate the organic layer is washed with water and saturated sodium chloride dried filtered and concentrated in vacuo the residue is purified by chromatography silica gel ethyl acetate hexane.