2 2 ml of methanol was added 1 0 ml of 40 sodium hydroxide in water at 10 u00b0 c after stirring overnight at room temperature a solid precipitated the precipitate was recrystallized from methanol to afford 350 mg 87 1 of a white flaky solid mp 54 9 55 8 u00b0 c lit mp 54 55 u00b0 c noyce and jorgenson j am chem soc 1963 85 2420 2426 1 h nmr 250 mhz u03b48 33 8 26 d 1 h 8 05 7 97 m 3 h 7 57 7 49 m 3 h 7 30 m 1 h 6 61 6 57 d 2 h 3 92 s 6 h 13 c nmr 62 7 mhz 192 3 160 6 139 2 136 0 132 4 131 7 128 6 125 1 113 1 105 8 103 9 56 0 ppm 2 6 dichloro 2 u2032 6 u2032 dimethoxychalcone 40 to a solution of 2 6 dichlorobenzaldehyde 485 mg 2 77 mmol and 2 6 dimethoxyacetophenone 500 mg 2 77 mmol in 4 1 ml of methanol was added 1 0 ml of 40 sodium hydroxide in water at 10 u00b0 c after stirring for 1 5 hours at room temperature a solid appeared and was filtered the precipitate was recrystallized from methanol to afford 481 mg 51 5 of faint yellow needles mp 126 8 127 8 u00b0 c 1 h nmr 250 mhz u03b47 48 7 42 d 1 h 7 37 7 31 m 3 h 7 11 7 04 d.