chittenden g j f verhagen h 2003 u201c synthesis of isothiocyanate derived mercapturic acids u201d eur j med chem 38 729 737 26 park s hayes b l marankan f mulhearn d c wanna l mesecar a d santarseiro b d johnson m e venton d l 2003 u201c regioselective covalent modification of hemoglobin in search of antisickling agents u201d j med chem 46 936 953 27 remiszewski s w sambucetti l c atadja p bair k w cornell w d green m a howell k l jung m kwon p trogani n walker h 2002 u201c inhibitors of human histone deacetylase synthesis and enzyme and cellular activity of straight chain hydroxamates u201d j med chem 45 753 757 28 manesh c kuttan g 2003 u201c anti tumour and anti oxidant activity of naturally occurring isothiocyanates u201d j exp clin can res 22 193 199 29 wattenberg l w 1977 u201c inhibition of carcinogenic effects of polycyclic hydrocarbons by benzyl isothiocyanate and related compounds u201d j nat can inst 58 395 398 30 nakamura y 2004 u201c cancer chemoprevention by isothiocyanates cancerous cell specific control of cell proliferation and its molecular mechanism u201d kankyo hen 39 igen kenkyu 26 253 258 31 akagi k masashi s ogawa k hirose m goshima h shirai t 2003 u201c involvement of toxicity as an early event.