compressing the powder mixture into tablets the novel process is especially useful for formulating drugs of which the unit dose is about 50 u03bcg to 1000 u03bcg the solvent typically is one in which the drug is readily soluble and which can be easily evaporated such as ethanol methanol acetone tetrahydrofuran or the like the directly compressible tableting vehicle is one such as processed forms of dicalcium phosphate dihydrate compressible sucrose lactose mannitol microcrystalline cellulose other celluloses or modified starches as lubricant there can be used any lubricant known in the art such as magnesium stearate calcium stearate stearic acid glyceryl behenate or the like other excipients well known in the art may be added as fillers such as colloidal silicon dioxide calcium sulfate or the like the amount of solvent used to introduce the active ingredient should be held to a minimum so that evaporation and removal of it is facilitated ______________________________________ per 6000 tablets______________________________________active ingredient anhydrous 50 u03bcg 0 300 gmmicrocrystalline cellulose nf 75 9 mg 455 0 gmpregelatinized starch nf 23 0 mg 138 0 gmmagnesium stearate impalpablepowder nf 1 0 mg 6 0 gm______________________________________ the active ingredient was dissolved in 6 ml of anhydrous ethanol sd3a and added to microcrystalline cellulose contained in a blender bowl while being mixed at 40 50 rpm the active ingredient was rinsed in with 2 u00d7 2 ml portions of anhydrous ethanol mixing was continued for 6 minutes at 40 rpm the microcrystalline cellulose active ingredient.