three different concentration levels are used in the present embodiment it is particularly preferable to use three levels with certain intervals for example a low level hereinafter referred to as l a middle level hereinafter referred to as m and a high level hereinafter referred to as h l denotes the vicinity of a lower limit of the reference range of the normal measurement value m denotes the vicinity of an upper limit of the reference range thereof and h denotes a level which is at least twice the normal measurement value although any measurement items that can be measured with the automatic analyzer can be used it is desirable that each item can be measured with both the enzyme method and immunization more than about 300 measurement items are known main items include total protein tp albumin alb lactate dehydrogenase ld aspartate aminotransferase ast alanine aminotransferase alt alkaline phosphatase alp amylase amy pancreatic amylase p amy leucine aminopeptidase lap u03b3 glutamyl transpeptidase u03b3gt cholinesterase che creatine kinase ck total cholesterol t cho neutral fat tg hdl cholesterol hdl c ldl cholesterol ldl c free fatty acid fea urea nitrogen un creatinine cre uric acid ua glucose glu hemoglobin a1c hba1c lactic acid la pyruvic acid pa total bilirubin t bil direct bilirubin d bil calcium ca sodium na inorganic phosphorus ip serum iron fe unsaturated iron binding capacity uibc creatine kinase mb ck mb phospholipid pl c reactive protein crp rheumatoid cause rf immunoglobulin g igg immunoglobulin a iga immunoglobulin m igm complement 3 c3 complement 4 c4 antistreptolysin o aso etc in particular uric acid ua aspartate aminotransferase ast alanine aminotransferase alt creatinine cre u03b3 glutamyl transpeptidase u03b3gt etc are known for the dispersion tendency of low concentration.