1065 10 4 mg 0 015 mm is dissolved in pyridine 150 u03bcl and put under an atmosphere of nitrogen decanoyl chloride 10 u03bcl is added and the reaction is stirred at room temperature for 50 minutes the crude solid product is obtained by precipitation with water and centrifugation it is purified by column chromatography on 2 g of silica gel in 14 86 dimethylformamide toluene fractions are of one or two ml the desired product found in fractions 7 15 weight 7 1 mg 54 yield ms fab calcd for c 47 h 52 cin 7 o 9 893 3515 measured 893 3472 a 9 9 mg 0 014 mm quantity of cc 1065 in dry pyridine 150 u03bcl under nitrogen is treated with myristoyl chloride 9 mg 0 036 mm after stirring three hours at room temperature the product is precipitated with water and isolated by centrifugation the solid 16 mg is chromatographed on a 2 5 g silica gel column fractions of 1 2 ml are collected elution with 13 87 and 25 75 dmf toluene brought the product off in fractions 11 19 an 11 yield 1 5 mg is obtained ms fab calcd for c 51 h 61 cin 7 o 9 950 4219 measured 950 4175 an 11 mg 0 016 mmole quantity cc 1065 is dissolved in 150 u03bcl pyridine add 4 u03bcl.