and clinics one isolate sjch 12 exhibited a broad range of activity against mdr strains tested including methicillin resistant staphylococcus aureus application_number US 200913060448 A description the present invention provides novel polypeptide compositions that show a wide range of antibacterial activity the active compounds were isolated from marine bacteria isolated from core sample sediments which included coarse brown sediment with worm casings visible core sample 1 rocky with grey sediment core sample 2 and grey sediment containing rock like material core sample 3 bacterial colonies were isolated from these samples of 13 bacterial colonies at least 1 putative new species of bacterium was isolated and 2 bio activities identified one of which was a highly antimicrobial peptide identified as 08 1083 and the other an unidentified compound with adhesive properties of 93 core sample extracts 20 active compounds were indicated in in vitro tox a assays eleven samples were taken from the three core samples and plated on lb agar or grown in lb broth thirteen bacterial isolates were colony purified and identified as sjch 1 13 of the 13 isolates 4 exhibited antimicrobial activity sjch 12 isolate showed activity against 8 of 11 organisms tested while sjch 11 exhibited activity against 3 of the organisms sjch 10 against two and sjch 3 against only one see table 2 marine seabed samples were obtained from an odyssey dive site located in the atlantic ocean approximately 100 miles east of the georgia coastline samples comprised seabed material recovered by odyssey marine exploration tampa fla remote operated vehicle during routine dive operations at 1700 feet samples were stored at 4 u00b0 c or ambient temperature prior to analysis bacteria isolate sjch 12 was deposited on oct 20 2008 at.