detailed examination and description of multiple parameters of differences in hair is greatly facilitated by the ability to examine the hairs at high magnification under stable conditions of fixed focal length and subject position utilizing the capabilities of the slit lamp biomicroscope the figure shows the actual results on the eyelashes of a patient treated for glaucoma with lumigan u00ae bimatoprost for 6 months a topical cream is prepared as follows tegacid and spermaceti are melted together at a temperature of 70 80 u00b0 c methylparaben is dissolved in about 500 gm of water and propylene glycol polysorbate 80 and bimatoprost are added in turn maintaining a temperature of 75 80 u00b0 c the methylparaben mixture is added slowly to the tegacid and spermaceti melt with constant stirring the addition is continued for at least 30 minutes with additional stirring until the temperature has dropped to 40 45 u00b0 c finally sufficient water is added to bring the final weight to 1000 gm and the preparation stirred to maintain homogeneity until cooled and congealed a topical cream is prepared as follows tegacid and spermaceti are melted together at a temperature of 70 80 u00b0 c methylparaben is dissolved in water and propylene glycol polysorbate 80 and bimatoprost are added in turn maintaining a temperature of 75 80 u00b0 c the methylparaben mixture is added slowly to the tegacid and spermaceti melt with constant stirring the addition is continued for at least 30 minutes with additional stirring until the temperature has dropped to 40 45 u00b0 c finally sufficient water is added to bring the final weight to 1000 gm and the preparation stirred to.