by including dgj the enzyme activity showed significantly increase in these cell cultures the enzyme activity in mutant lymphoblasts reached to 64 of those found in normal lymphoblasts cultured without dgj at the fifth day the enzyme activity in normal lymphoblasts was also enhanced 30 after cultivation with dgj dgj concentration dependence of u03b1 gal a enhancement in transfected cos 1 cells tgm fibroblasts and lymphoblasts with a phenotype of r301q was examined as shown in fig4 the enzyme activity increased with the increase in the concentration of dgj in the range of 0 2 20 u03bcm in transfected cos 1 cells fig4 a and lymphoblasts fig4 c and between 0 2 200 u03bcm in tgm fibroblasts fig4 b respectively a higher concentration of dgj suppressed the enhancement effect de hnj showed the same effect on the enhancement of u03b1 gal a in cos 1 cells transfected with a mutant cdna of the enzyme r301q at the higher concentrations 1 1000 u03bcm compared with dgj fig5 it is clear that de hnj at 1 mm in culture medium did not inhibit intracellular enzyme activity of cos 1 cells 0055 fig6 shows an experiment to measure stabilization of dgj enhanced u03b1 gal a in lymphoblasts the cells were cultured.