the differential amplifier in fig1 row selection signals control this multiplexer as well as the other analog mux shown in fig1 which selects the analog switches in fig1 to enable driving and sensing of a row the output of the differential amplifier shown at the top of fig1 connects to the high resolution 24 bit adc in fig2 fig2 also shows a controller embodiment that receives instructions from a processor via an spi bus and selects the appropriate cell s 12 in an array as a result choices for dac and adc resolutions are typically chosen according to the accuracy requirements of a particular application according to this invention differential analysis using thermal techniques can be performed by way of a number of alternative embodiments for thermal analysis where ovens and thermocouples are used it is traditional to have a pair of similar crucibles and temperature sensing mechanisms in order to analyze both an analyte and a reference simultaneously the results then being compared to produce a differential result the present invention offers alternative embodiments where results to be compared differentially are acquired sequentially for both dta and dsc one embodiment of an analysis system according to the present invention and compared with known dta and dsc methodologies utilizes the same sensor probe.