<s>[INST] Given an abstract text, please determine whether it contains any drug mentions. Provide a 'Yes' or 'No' answer based on the presence or absence of drugs. Abstract Text: Colorectal Nociceptive Processing In The Caudal Ventrolateral Medulla And The Lateral Parabrachial Nuclei Is Increased In A Mouse Model Of Chronic Visceral Hypersensitivity And Is Reversed By Chronic Linaclotide Treatment.[/INST] Yes</s>