<s>[INST] Given an abstract text, please determine whether it contains any drug mentions. Provide a 'Yes' or 'No' answer based on the presence or absence of drugs. Abstract Text: Vonoprazan Appears Cost-Effective And Cost-Saving To Manage Heartburn In Patients With Reflux Esophagitis Failing An Over-The-Counter Proton Pump Inhibitor[/INST] Yes</s>