<s>[INST] Given an abstract text, please determine whether it contains any drug mentions. Provide a 'Yes' or 'No' answer based on the presence or absence of drugs. Abstract Text: A Randomized Trial Of Vedolizumab Dose Optimization In Patients With Moderate To Severe Ulcerative Colitis Who Have Early Nonresponse And High Drug Clearance: The Enterpret Trial[/INST] Yes</s>