<s>[INST] Given an abstract text, please determine whether it contains any drug mentions. Provide a 'Yes' or 'No' answer based on the presence or absence of drugs. Abstract Text: Plecanatide Improves Abdominal Pain, Bloating, And Straining Symptoms In Adults With Irritable Bowel Syndrome With Constipation (Ibs-C):A New Composite Endpoint Analysis Of Two Randomized, Phase 3 Trials[/INST] Yes</s>