<s>[INST] Given an abstract text, please determine whether it contains any drug mentions. Provide a 'Yes' or 'No' answer based on the presence or absence of drugs. Abstract Text: A Randomized, Double-Blind, Phase 3 Study To Evaluate The Efficacy And Safety Of Vonoprazan-Based Versus Esomeprazole-Based Bismuth-Containing Quadruple Therapy For The Eradication Of Helicobacter Pylori Infection In China[/INST] Yes</s>