<s>[INST] Given an abstract text, please determine whether it contains any drug mentions. Provide a 'Yes' or 'No' answer based on the presence or absence of drugs. Abstract Text: Lubiprostone Is A General Activator Of Camp-Gated Ion Channels And Clc-2 Has A Minor Role In Its Prosecretory Effect In Intestinal Epithelial Cells[/INST] Yes</s>