But boss Rafa Benitez is missing Dwight Gayle, Aleksandar Mitrovic, Vurnon Anita and Isaac Hayden through injury.
Birmingham manager Gianfranco Zola says he may rest defender Michael Morrison and striker Lukas Jutkiewicz.
Blues are without new signing Craig Gardner (ineligible), Clayton Donaldson (knee) and Greg Stewart (Achilles).
The teams drew 1-1 in the original tie at St Andrew's, Jutkiewicz's strike cancelling out Daryl Murphy's early opener.
Whoever wins Wednesday's replay will travel to League One side Oxford United in the fourth round on 28 January.
Media playback is not supported on this device
Newcastle manager Rafa Benitez:
"Isaac Hayden is doing well, hopefully not serious. Vurnon Anita has a problem with his ankle, could be six weeks, more or less.
"Dwight Gayle is much better than expected. No time frame, he will be assessed every game. It's too early."
Birmingham manager Gianfranco Zola:
"It's a tough place to go but I will make some changes because we also have a very important game at Blackburn on Saturday.
"I have to try to change some players, especially because we have one or two that have little issues physically and I want to preserve them."
Attempt missed. Yoan Gouffran (Newcastle United) left footed shot from the centre of the box is close, but misses to the left.
Corner,  Newcastle United. Conceded by Che Adams.
Attempt blocked. DeAndre Yedlin (Newcastle United) right footed shot from the right side of the box is blocked.
Corner,  Newcastle United. Conceded by Jonathan Grounds.
Foul by Achraf Lazaar (Newcastle United).
Che Adams (Birmingham City) wins a free kick on the right wing.
Attempt missed. David Cotterill (Birmingham City) right footed shot from outside the box is close, but misses to the left from a direct free kick.
Foul by Cheick Tioté (Newcastle United).
David Cotterill (Birmingham City) wins a free kick in the attacking half.
Corner,  Birmingham City. Conceded by Matt Ritchie.
Attempt saved. Jonjo Shelvey (Newcastle United) right footed shot from outside the box is saved in the bottom right corner.
Attempt missed. David Cotterill (Birmingham City) right footed shot from outside the box is close, but misses to the right.
Attempt missed. Viv Solomon-Otabor (Birmingham City) right footed shot from outside the box is close, but misses to the right.
Foul by Yasin Ben El-Mhanni (Newcastle United).
David Cotterill (Birmingham City) wins a free kick in the defensive half.
Goal!  Newcastle United 1, Birmingham City 0. Matt Ritchie (Newcastle United) converts the penalty with a left footed shot to the centre of the goal.
Penalty Newcastle United. Yoan Gouffran draws a foul in the penalty area.
Adam Legzdins (Birmingham City) is shown the yellow card for a bad foul.
Penalty conceded by Adam Legzdins (Birmingham City) after a foul in the penalty area.
Attempt missed. David Cotterill (Birmingham City) left footed shot from outside the box is close, but misses the top left corner.
Viv Solomon-Otabor (Birmingham City) wins a free kick in the defensive half.
Foul by Cheick Tioté (Newcastle United).
First Half begins.
Lineups are announced and players are warming up.
Newcastle midfielder Jonjo Shelvey is available for the FA Cup third-round replay against Championship rivals Birmingham City after a five-match ban.