The sides meet in the Co Antrim Shield decider at Ballymena on Tuesday night.
An exciting last-eight line-up also includes two derbies with Portadown hosting holders Glenavon while Coleraine visit Ballymena United.
Dungannon Swifts go to Warrenpoint Town, the only team outside the top-flight still in the competition.
"It's a big tie between two teams who have played really well for the last 12 months," said Crusaders boss Stephen Baxter.
"We look forward to the challenge - it will be a great day with a big atmosphere."
The Premiership's top two teams will meet the in Irish Cup quarter-finals with Crusaders having home advantage against Linfield on Saturday, 4 March.