The dead woman, who has not been named but is believed to be in her 50s, was found at a house in Holmfield Avenue on Saturday.
Mohammed Member, 25, Shafiq Member, 29, and Fatima Patel, 27, all of Holmfield Avenue, were remanded in custody ahead of a crown court appearance.
Formal identification of the dead woman has yet to take place.
Updates on this story and more from Leicestershire
Three people have appeared in court charged with murdering a woman at a house in Leicester.