《黄帝内经·灵枢·本输》
大肠的脉气运行，上合于手阳明经，脉气出于商阳穴，商阳在手大指食指尖端的内侧，称之为井金；脉气由此流于食指内侧本节前的二间穴，称之为荥；脉气由此注于食指本节后面陷中的三间穴，称之为输；脉气由此过于合谷穴，合谷在手大拇指和食指的歧骨中间，称之为原；脉气由此行于阳溪穴，阳溪在手腕上两筋中间的陷凹中，称之为经；脉气由此入归于曲池穴，曲池在肘外辅骨横纹头陷中，屈肘横肱取之，称之为合，这就是手阳明大肠经所属的五输穴和原穴。
大肠上合手阳明，出于商阳，商阳，大指次指之端也，为井金；溜于本节之前二间，为荥；注于本节之后三间，为俞；过于合谷，合谷，在大指岐骨之间，为原；行于阳溪，阳溪，在两筋间陷者中也，为经；入于曲池，在肘外辅骨陷者中，屈臂而得之，为合，手阳明也。
The Qi of large intestine runs, intersects with hand Yang Ming meridian at the upper end, Qi comes out from Shangyang acupoint, Shangyang is on the inner side of the tip of thumb and index finger of hand, namely Jingjin; Qi runs from here to Erjian acupoint, which is in the front of the first joint of inner side of index finger, namely Rong; Qi gathers from here to Sanjian acupoint, which is at the sunken middle of the back of the first joint of index finger, namely Shu; Qi runs from here to Hegu acupoint, Hegu is in the middle of the divergent bones of thumb and index finger, namely Yuan; Qi runs from here to Yangxi acupoint, Yangxi is in the sunken recess between the two tendons on the upper wrist, namely Jing; Qi enters and returns to Quchi acupoint, Quchi is at the sunken middle of the head of transverse lines of the assistant bone outside elbow, and is taken when the elbow is bent and humerus is horizontal, namely He. This is the five Shu acupoints and original point of hand Yang Ming large intestine meridian.