《黄帝内经·素问·气穴论》
若邪气溢满，正气壅滞，则脉发热，肌肉败坏，荣卫之气不能畅行，必将郁热腐肉成脓，内则消烁骨髓，外则可溃大肉，若邪留连于关节肌腠，必使髓液皆溃为脓，而使筋骨败坏。
邪溢气壅，脉热肉败，荣卫不行，必将为脓。内销骨髓，外破大腘。留于节凑，必将为败。
If the evil Qi is overflowing and the Qi is blocked, the pulse will get fever, the muscles will be damaged, and the Qi of荣卫 cannot circulate smoothly. The heat will surely make the flesh rot and form pus. The inside will melt the bone marrow, and the outside may溃大肉. If the evil remains in the joints and muscles, the marrow and liquid will surely become pus, and the muscles and bones will be damaged.