there are many things that can cause swelling below the knee known as edema. it is usually a result of fluid retention and can be caused by several different health conditions. cyclosporine has been associated with causing edema in less than 2% of the people that take it. i suggest you contact the prescriber and notify him/her of your father's swelling. they can tell you how best to handle it considering his past medical history.
my father's legs are swollen from the knees down. he is taking cyclosporine. is this a side effect of the drug?