you can use a pad (available in pharmacies) to protect your toe or consider having your shoes custom fit (many shoe stores will do this now). better yet see a podiatrist and have your feet/toes x-rayed. a callous may indicate that you have a bone spur underneath or even a neuroma (painful). rather than self-treat it would be best to be properly evaluated by an expert.
how can you prevent caluse on your baby toe? . i am in scrubs all day and i have these comfortable shoes that i wear which is not tight at all but at the end of the day my little baby toes be killing me. any suggestions?