ibuprofen can be given every six hours. tylenol can be given every four hours. while i am not a fan of using both many clinicians allow their patients to do it and many people safely do it on their own. personally i think just one or the other is sufficient but migraines (assuming she has a true medically-diagnosed migraine. not all bad headaches are "migraines" then she may need to take something stronger something different or at least a more appropriate dose. i assume that your girlfriend is an adult with an adult weight so a consultation with her medical provider would seem a appropriate. do not take more than the recommended maximum adult dose of either one of these over-the-counter medications!
my girlfriend took 400mg ibuprofen this morning and 400mg tylenol at 6 est can she take either again? . migraines and a bit of a tooth ache still from a removed impacted premolar.