a high thyroglobin antibody level in and of itself does not mean you have thyroid disease. they are found in nearly 20% of all women. however high levels of thyroglobulin antibodies associated with other thyroid antibodies are found in 80 to 90% of people with immune mediated inflammation of the thyroid (hashimoto’s thyroiditis). this is the most common type of thyroid hormone deficiency in the u. s. thyroglobulin antibodies are also found in pregnant women relatives of patients with hashimoto’s thyroiditis and in people with other immune mediated diseases such as type 1 diabetes. the usual course of hashimoto's thyroiditis is gradual loss of thyroid function. antibodies to thyroglobulin are considered to occur as a result of damage to the thyroid from special white blood cells (t cells). common symptoms of thyroid hormone deficiency include fatigue being cold all the time weight gain constipation dry skin and menstrual irregularities. since these symptoms occur in other diseases it is important not to always blame thyroid deficiency as the cause. fortunately laboratory tests for thyroid function make this diagnosis relatively easy. however because loss of thyroid hormone develops over time and antibodies can herald problems you will want to follow-up with your doctor about your thyroid tests and your symptoms.
what does it mean if your thyroglobin ab are very high but all the others are normal? and how does that affect the body? . i am wondering if the thyroglobin ab being high could correlate to the weight gain(15+ lbs a month and can't lose it) breast enlargement(2 cup sizes) fatigue and lack of menstration. i have been tested for cancer(negative) and i have no family history of these issues. from the research i have done i cannot find an answer so i am hoping that someone could enlighten me so i would have a stepping stone the next time i went to the doctor about this.