you could but it might make you very drowsy because both benadryl and alka-seltzer plus cold do that. there isn't any interaction with the tylenol though the alka seltzer plus cold has aspirin in it. you'd be taking 2 pain relievers and 2 antihistamines. alka-seltzer plus cold effervescent tablets sparkling original has aspirin /pain reliever-fever reducer. chlorpheniramine maleate/ antihistamine. phenylephrine bitartrate/nasal decongestant. here's what i found in the interaction checker: <link> significant - monitor closely: potential for interaction alka-seltzer plus cold oral + benadryl allergy oral benadryl allergy oral increases and alka-seltzer plus cold oral decreases sedation and drowsiness significant - monitor closely: potential for interaction alka-seltzer plus cold oral + benadryl allergy oral alka-seltzer plus cold oral and benadryl allergy oral both increase sedation and drowsiness
can you take alka seltzer plus for a cold along with benadryl and tylenol for a headache?