there are no oral medicines that are routinely used to treat common warts although some people have tried the cimetidine (tagomet) but this is certainly an off-label use with mixed results. personally i have never used it. my suggestion would be for him to see a good dermatologist. someone who can work with him closely trying different high-end treatments until a cure is orchestrated. he has definitely tried lots of things but i have never met a wart that i couldn't (eventually) kill with persistent treatments. i use liquid nitrogen most of the time but there are more topical (prescription) treatments that can be used if the dermatologist feels it is appropriate.
warts on hands tried home remedies o/c med derm. burned off removed by surgeon and imiquimod. back and spreading mor. this is my 19 yr old son and we have been fighting these for 3+ years now. they are spreading rapidly and we have no clue where else to turn. we have tried all the home remedies we can find including duct tape super glue apple cider vinegar and on and on. the surgeon had to put 5 stitches on the palm of his hand when he removed one and it's back and larger. is there an oral medicine he could possibly try? he now has about 18 on one hand