when a patient responds by forming keloid scars there is a greater than average chance that this will continue to occur. i assume that as you mention she has been given treatments that included shots she has access to a physician who can help you make an appropriate decision in this regard. surgery is not as good an option for your wife but you should discuss both microdermabrasion and laser resurfacing with your wife's doctor. both are better alternatives and work by focusing on the over-development of collagen that is the key problem with keloid scarring.
my wife is considering surgery for itchy painful keloid scars after shots didn't help. is that the best option?