acetaminophen can be liver toxic in high doses usually very high doses perhaps taken as a suicidal gesture. the amount of acetaminophen that is considered toxic varies a bit based on the person's size and of course if the person was ingesting alcohol or other drugs. it is generally felt that 150mg of acetaminophen per kilo (2. 2 pounds) of body weight or about 7-10 grams (7 000 to 10 000 mg). toxicity can damage can occur at lower dosages however so it is always wise to follow dosage instructions to the letter unless of course you are interested in a liver transplant.
someone i know took too many tylenol. how many tylenol would you have to take to do permanent damage to vital organs?