i read your concerns. i feel that topamax 200mg which works well for migraine has a little role in bipolar disorders. studies show that monotherapy with topamax is not recommended but instead of taking topamax you can try sodium valproate (depakote xr 750mg at night) which will be helpful to you in both your migraine and bipolarity. divalpoex sodium (depakote) has sedative property as a side effect. so it will be helpful to you in your insomnia. if you take 750 mg of dep. at night then you can reduce the night dosage of clonapin and gradually increase the dosage of depakote to 1000 mg and reduce the clonapin. you can also take 500mg in morning and 1000mg at night. and i feel that if you are feeling depressed then only you should take paxil otherwise there is no role of it in bipolar disorder. if your migraine is severe then you should take propranolol 10mg twice a day. but you have to take care about your heart because you complained about side effects of seroquel. propranolol is beta blocker it is used in prophylaxis for migraine. and i feel that if you use it you finally will get relief from your migraine. i do not know whether you have ever tried non benzos like zolpidem zopiclone eszopiclone. you should try that also for your sleep. i feel that these will satisfy some of your concerns. you can book for an online therapy at icliniq for further consultation with me either via video session or on phone.
i am 26 years old female who has ptsd bipolar and major depression. i also suffer from migraines anxiety and insomnia.