this sounds like a side effect you should monitor closely. sometimes itching can progress into a more severe allergic reaction. some opioid pain relievers (like vicodin) can cause a release of histamine in the body. this histamine release causes itching. think about the way pollen causes your nose to itch. that itching is called a 'histamine reaction ' and you take an antihistamine to make the itching stop. the same thing can happen in some people when they take opioid pain relievers. you can take an antihistamine with the vicodin to see if that helps stop the itching. i'd recommend you speak to your care provider to see if you should stop the vicodin and take something else. of course if you experience swelling of the face tongue or throat along with the itching you should seek emergency medical attention. these can be symptoms of a life-threatening allergic reaction. itching is a not-uncommon side effect from opioid pain relievers in my experience. but keep an eye on your symptoms anyway. wishing you well!
why do vicidon make me itch