it is generally accepted that people can have a "metal allergy" and associated difficulty with a total knee prosthesis made out of metal. it is a very hard diagnosis to confirm and the options to address it included a revision to a prosthesis made out of titanium and or a ceramic "lined" component. there are times where a revision surgery like this really helps the patient and other times when it does not seem to help that much. the questions of metal allergy comes up when a patient has knee replacement that is painful despite the fact that the radiographs look good and the work up for infection and loosening is negative. this is a very tough problem for the patient and for the reasons outlined above the surgeon as well.
is it possible for the body to reject a knee replacement implant?