doctors do not know the exact cause of eczema but a defect of the skin that impairs its function as a barrier possibly combined with an abnormal function of the immune system are believed to be important factors. studies have shown that in people with atopic dermatitis there are gene defects that lead to abnormalities in certain proteins (such as filaggrin) that are important in maintaining the barrier of normal skin. some forms of eczema can be triggered by substances that come in contact with the skin such as soaps cosmetics clothing detergents jewelry or sweat. environmental allergens (substances that cause allergic reactions) may also cause outbreaks of eczema. changes in temperature or humidity or even psychological stress can lead to outbreaks of eczema in some people.
what causes eczema?