probably not but please ask your dermatologist -- someone who uses accutane on a regular basis for patients. over-the counter supplements like creatine were not likely tested against prescription medications like accutane so there is little or no data about interactions. creatine doesn't really do that much as far as muscle building. your exercise regime is the most critical element not your supplements.
will there be any adverse interactions between accutane (40mg/day) and the workout supplement creatine (5g/day)? . im a 22 year old athletic male.