it would depend on why you take aspirin and which over-the-counter cold/ flu medication you are referring to. if you take aspirin you would want to avoid cold and flu medications that contained an anti-inflammatory like ibuprofen and stick with cold and flu medications that contain acetaminophen. always check with the pharmacist to ensure that the cold and flu medication you are choosing is right for you.
is it ok to take aspirin and an over-the-counter cold/flu medicine together?