Melanin-loaded CpG DNA hydrogel for modulation of tumor immune microenvironment.Photothermal immunotherapy has emerged as one of the most potent approaches for cancer treatment, but this strategy has suffered from the lack of biodegradability of the photoresponsive materials.  In this study, we aimed to develop biodegradable materials for photothermal immunotherapy.  In vivo, local administration of Mel/G/DH (+NIR) exerted photothermal killing of primary tumors and induced maturation of DC in lymph nodes. 
THERM