A mobile digital olfactory testing system (DOTS) was developed, consisting of an odor delivery system (DOTS-ODD) and a mobile application program (DOTS-APP) connected wirelessly.  The University of Pennsylvania Smell Identification Test was implemented in DOTS and compared to its commercial product on a cohort of 80 normosmic subjects and a clinical cohort of 12 Parkinson's disease patients.  The smell identification scores obtained from the DOTS and standard UPSIT commercial test are highly correlated (r = 0.714, P < .001), and test-retest reliability coefficient was 0.807(r = 0.807, P < .001).  The DOTS is customizable and mobile compatible, which allows for implementation of standardized olfactory tests and the customization of investigators' experimental paradigms.  The DOTS-APP on mobile devices offers capabilities for a broad range of on-site, online, or remote clinical and scientific chemosensory applications.
DOTS