Chromosome compaction and chromatin stiffness enhance diffusive loop extrusion by slip-link proteins.We use Brownian dynamics simulations to study the formation of chromatin loops through diffusive sliding of slip-link-like proteins, mimicking the behaviour of cohesin molecules. 
Brownian dynamics simulations
Chromosome compaction and chromatin stiffness enhance diffusive loop extrusion by slip-link proteins.We use Brownian dynamics simulations to study the formation of chromatin loops through diffusive sliding of slip-link-like proteins, mimicking the behaviour of cohesin molecules. 
cohesin molecules
We recently proposed that diffusive sliding is sufficient to explain the extrusion of chromatin loops of hundreds of kilo-base-pairs (kbp), which may then be stabilised by interactions between cohesin and CTCF proteins. 
CTCF proteins