SPIRE-a software tool for bicontinuous phase recognition: application for plastid cubic membranes.Bicontinuous membranes in cell organelles epitomize nature's ability to create complex functional nanostructures.  Here we present a tool, Surface Projection Image Recognition Environment (SPIRE), to identify bicontinuous structures from TEM sections through interactive identification by comparison to mathematical "nodal surface" models.  Using our SPIRE tool, we achieved a robust identification of the bicontinuous diamond surface as the dominant PLB geometry in angiosperm etioplasts in contrast to earlier long-standing assertions in the literature. 
SPIRE
Here we present a tool, Surface Projection Image Recognition Environment (SPIRE), to identify bicontinuous structures from TEM sections through interactive identification by comparison to mathematical "nodal surface" models. 
Surface Projection Image Recognition Environment