Identification and structural characterization of febuxostat metabolites in rat serum and urine samples using UHPLC-QTOF/MS.Febuxostat is a novel nonpurine type of highly selective xanthine oxidoreductase inhibitor. 
UHPLC-QTOF/MS
The febuxostat metabolites were predicted by biotransformation software and transformed to a personal compound database to quickly determine the possible metabolites from the MS1 data. 
biotransformation software
The possibility of the MS/MS fragmentation was calculated by the Molecular Structure Correlator software. 
Molecular Structure Correlator software