Migrative Carbofluorination of Saturated Amides Enabled by Pd-Based Dyotropic Rearrangement.Directly editing an all-carbon quaternary carbon itself of nonstrained acyclic molecules remains underexploited despite the recent advances in the fields of both C-H and C-C bond activation. 
Pd-Based Dyotropic Rearrangement
Herein, we report a palladium-catalyzed migrative carbofluorination of saturated amides enabled by the activation of both the C(sp3)-H and the Cquaternary-Cσ bonds. 
Palladium-catalyzed migrative carbofluorination
DFT calculations indicate that the dyotropic rearrangement proceeds through an unusual anti-selective [2.1.0] bicyclic transition state. 
DFT calculations