The WRKY10-VQ8 module safely and effectively regulates rice thermotolerance.WRKY transcription factors (TFs) play crucial roles in biotic and abiotic stress responses.  However, their roles in thermal response are still largely elusive, especially in rice.  In this study, we revealed the functions of WRKY10 TF and VQ8 protein containing VQ motif in rice thermotolerance.  Overexpression of WRKY10 or loss of VQ8 function increases thermosensitivity, whereas conversely, overexpression of VQ8 or loss of WRKY10 function enhances thermotolerance.  Our study demonstrates that WRKY10 negatively regulates thermotolerance by modulating the ROS balance and the hypersensitive response and that VQ8 functions antagonistically to positively regulate thermotolerance. 
THERM