IRGS: an immune-related gene classifier for lung adenocarcinoma prognosis.BACKGROUND

IRGS
We first obtained publicly accessible lung adenocarcinoma RNA expression data from The Cancer Genome Atlas (TCGA) for differential gene expression analysis and then filtered immune-related genes based on the ImmPort database.  Gene expression data from a total of 524 lung adenocarcinoma patients from TCGA were used for model development. 
TCGA
We first obtained publicly accessible lung adenocarcinoma RNA expression data from The Cancer Genome Atlas (TCGA) for differential gene expression analysis and then filtered immune-related genes based on the ImmPort database. 
ImmPort database
By using the lasso algorithm and multivariate Cox Proportional-Hazards (CoxPH) regression analysis, we identified candidate genes for model development and validation. 
lasso algorithm
By using the lasso algorithm and multivariate Cox Proportional-Hazards (CoxPH) regression analysis, we identified candidate genes for model development and validation. 
multivariate Cox Proportional-Hazards (CoxPH) regression analysis