Whole-exome sequencing reveals novel variants associated with abnormal uterine bleeding caused by copper intrauterine device.Aim: This study aimed to explore the genetic risk factors and validate variants of abnormal uterine bleeding after copper intrauterine device insertion.  Methods: Whole-exome sequencing was performed and several variants were validated by Sequenom MassARRAY. 
Whole-exome sequencing
Methods: Whole-exome sequencing was performed and several variants were validated by Sequenom MassARRAY. 
Sequenom MassARRAY