Cryo-EM structures of intermediates suggest an alternative catalytic reaction cycle for cytochrome c oxidase.Cytochrome c oxidases are among the most important and fundamental enzymes of life.  Here, we determined structures of up to 1.9 Å resolution of these intermediates by single particle cryo-EM. 
Cryo-EM
Here, we determined structures of up to 1.9 Å resolution of these intermediates by single particle cryo-EM. 
single particle cryo-EM