Fetal Skeletal Dysplasias that Involve the Face: Binder Syndrome and Nager Syndrome.Binder syndrome and Nager syndrome are part of the spectrum of skeletal dysplasias.  We present cases of Binder syndrome and Nager syndrome diagnosed by us prenatally.  We elaborate on the etiology of Binder syndrome and discuss the current classification of facial dysostoses.
Binder Syndrome
Fetal Skeletal Dysplasias that Involve the Face: Binder Syndrome and Nager Syndrome.Binder syndrome and Nager syndrome are part of the spectrum of skeletal dysplasias.  We present cases of Binder syndrome and Nager syndrome diagnosed by us prenatally. 
Nager Syndrome
Although exceedingly rare, both syndromes are amenable to prenatal diagnosis because they present with features that can be detected by prenatal ultrasound. 
prenatal ultrasound
Genetic prenatal diagnosis is sometimes possible but remains difficult if the etiology of the disease is not homogenous. 
genetic prenatal diagnosis