Developing Computational Model to Predict Protein-Protein Interaction Sites Based on the XGBoost Algorithm.The study of protein-protein interaction is of great biological significance, and the prediction of protein-protein interaction sites can promote the understanding of cell biological activity and will be helpful for drug development.  In this work, two imbalanced data processing strategies based on XGBoost algorithm were proposed to re-balance the original dataset from inherent relationship between positive and negative samples for the prediction of protein-protein interaction sites.  Experimental results demonstrated the effectiveness of our XGBoost-based method.
XGBoost
Developing Computational Model to Predict Protein-Protein Interaction Sites Based on the XGBoost Algorithm.The study of protein-protein interaction is of great biological significance, and the prediction of protein-protein interaction sites can promote the understanding of cell biological activity and will be helpful for drug development.  In this work, two imbalanced data processing strategies based on XGBoost algorithm were proposed to re-balance the original dataset from inherent relationship between positive and negative samples for the prediction of protein-protein interaction sites.  Experimental results demonstrated the effectiveness of our XGBoost-based method.
XGBoost
Developing Computational Model to Predict Protein-Protein Interaction Sites Based on the XGBoost Algorithm.The study of protein-protein interaction is of great biological significance, and the prediction of protein-protein interaction sites can promote the understanding of cell biological activity and will be helpful for drug development.  In this work, two imbalanced data processing strategies based on XGBoost algorithm were proposed to re-balance the original dataset from inherent relationship between positive and negative samples for the prediction of protein-protein interaction sites.  Experimental results demonstrated the effectiveness of our XGBoost-based method.
XGBoost