Intelligent MoS2-CuO heterostructures with multiplexed imaging and remarkably enhanced antitumor efficacy via synergetic photothermal therapy/ chemodynamic therapy/ immunotherapy.Rational design of biocompatible nanoplatforms simultaneously realizing multimodal imaging and therapeutic functions is meaningful to cancer treatment.  Herein, the MoS2-CuO heteronanocomposites are designed by integrating semiconductor CuO and flower-like MoS2 via a two-step hydrothermal method.  After loading bovine serum albumin (BSA) and immunoadjuvant imiquimod (R837), the obtained MoS2-CuO@BSA/R837 (MCBR) nanoplatforms realize the excellent computed tomography/infrared thermal/magnetic resonance multi-mode bioimaging as well as significantly enhanced antitumor efficacy of synergetic photothermal therapy (PTT)/chemodynamic therapy (CDT)/immunotherapy. 
THERM