Analysis of metabolic abnormalities in high-grade glioma using MRSI and convex NMF.Clinical use of MRSI is limited by the level of experience required to properly translate MRSI examinations into relevant clinical information.  Using 41 MRSI examinations (1.5 T, PRESS, TE 135 ms) from 22 glioma patients, four different patterns describing different types of abnormality were detected: edema, healthy without Glx, active tumor and necrosis.  The identified patterns were then evaluated on 17 MRSI examinations from nine different glioma patients. 
MRSI
Analysis of metabolic abnormalities in high-grade glioma using MRSI and convex NMF.Clinical use of MRSI is limited by the level of experience required to properly translate MRSI examinations into relevant clinical information. 
convex NMF
The results were compared against BraTumIA, an automatic segmentation method trained to identify different tumor compartments on structural MRI data. 
BraTumIA