A QCM-based rupture event scanning technique as a simple and reliable approach to study the kinetics of DNA duplex dissociation.Rupture Event Scanning (REVS) is applied for the first time within an approach based on dynamic force spectroscopy.  In the case where a mismatch is located at the farthest duplex end from the QCM surface, a substantial decrease in the position of the barrier between the bound and unbound states is observed. 
QCM
A QCM-based rupture event scanning technique as a simple and reliable approach to study the kinetics of DNA duplex dissociation.Rupture Event Scanning (REVS) is applied for the first time within an approach based on dynamic force spectroscopy. 
REVS
A QCM-based rupture event scanning technique as a simple and reliable approach to study the kinetics of DNA duplex dissociation.Rupture Event Scanning (REVS) is applied for the first time within an approach based on dynamic force spectroscopy. 
dynamic force spectroscopy