Development of Core@Shell γ-Fe2O3@MnO@SiO2 Nanoparticles for Hyperthermia, Targeting, and Imaging Applications.Monodispersed core@shell γ-Fe2O3@MnO nanoparticles have been prepared through thermolysis of iron and manganese oleate.  The nanoparticles are used as hyperthermia agents, and successful hyperthermia treatment in cancer cells is carried out.  As compared to γ-Fe2O3@SiO2, γ-Fe2O3@MnO@SiO2 shows the enhanced killing of cancer cells through hyperthermia.  This is the first report on this material, which is highly biocompatible for hyperthermia, imaging, and targeting.
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