Integrated Modeling of Structural Genes Using MCuNovo.Correct modeling of protein-coding genes based on genome and cDNA data is a prerequisite for functional studies.  To apply these methods in other organisms, we improved the algorithm (designated MCuNovo Gene Selector) and automated the data processing. 
MCuNovo
Various programs such as MAKER, Cufflinks, Oases, and Trinity have been developed, each with advantages and drawbacks.  We developed methods to evaluate the output of MAKER, Cufflinks, Oases and Trinity and select the best models to constitute the MCOT1.0 set for Manduca sexta, a biochemical model insect. 
MAKER
Various programs such as MAKER, Cufflinks, Oases, and Trinity have been developed, each with advantages and drawbacks.  We developed methods to evaluate the output of MAKER, Cufflinks, Oases and Trinity and select the best models to constitute the MCOT1.0 set for Manduca sexta, a biochemical model insect. 
Cufflinks
Various programs such as MAKER, Cufflinks, Oases, and Trinity have been developed, each with advantages and drawbacks.  We developed methods to evaluate the output of MAKER, Cufflinks, Oases and Trinity and select the best models to constitute the MCOT1.0 set for Manduca sexta, a biochemical model insect. 
Oases
Various programs such as MAKER, Cufflinks, Oases, and Trinity have been developed, each with advantages and drawbacks.  We developed methods to evaluate the output of MAKER, Cufflinks, Oases and Trinity and select the best models to constitute the MCOT1.0 set for Manduca sexta, a biochemical model insect. 
Trinity