Cyberknife Radiosurgery for Trigeminal Neuralgia.Introduction Image-guided robotic radiosurgery is an emerging minimally-invasive treatment option for trigeminal neuralgia (TN).  This study represents the largest single-center experience on CyberKnife radiosurgery for the treatment of TN so far reported.  Methods CyberKnife radiosurgery treatment was offered to patients with drug-resistant TN, after the failure of other treatments or refusal of invasive procedures.  Results Our group has treated 527 patients with Cyberknife radiosurgery at Centro Diagnostico Italiano (CDI), Milan, Italy, during the last decade. 
Cyberknife