Implementation and results of an enhanced recovery (fast-track) program in total knee replacement patients at a French university hospital.INTRODUCTION
 In total knee replacement (TKR) surgeries, "fast-track" or enhanced recovery after surgery (ERAS) programs are being developed, but their impact on care pathway quality and safety has not been fully explored in the French literature.  The present study aimed to compare results in TKR between fast-track and conventional pathways, addressing the following questions: (1) Are 90-day rates of complications, readmission and surgical revision higher with fast-track?  (2) Is mean length of stay (LoS) shorter with fast-track?  (3) Are postoperative pain and clinical results improved by fast-track?  And, (4) are patients and care staff satisfied with these new programs?


 Implementing fast-track for TKR in a university hospital center is beneficial for the patient and does not impair the quality and safety of care.


 A case-control study was performed using a retrospective analysis of prospectively collected data.  A fast-track program was implemented for TKR by modifying the care pathway.  This involved instituting a therapeutic education consultation, optimizing blood sparing, modifying surgical practices, and hastening early mobilization thus actively involving patients in their own management.  Between January 2017 and January 2019, 216 patients with a mean age of 69.23±7.80years and mean BMI of 30.15±4.79kg/m2 were included in the fast-track group, with 335 matched patients included in the conventional group.


 At 90days, there were no significant inter-group differences in rates of infection (fast-track=1.39%, conventional=0.90%; p=0.34), readmission (fast-track=3.24%, conventional=3.58%; p=0.49), or surgical revision (fast-track=2.78%, conventional=2.69%; p=0.298).  The visual analog scale (VAS) pain rating was 1.56±1.36 in the fast-track group versus 5±2.41 in the conventional group; p<0.001.  LoS was 3.17±1.59days in fast-track versus 7.25±1.85days in the conventional group; p<0.001.  Ninety-five percent of patients and 96% of care staff were satisfied with the fast-track program.


 DISCUSSION
 Fast-track implementation ensured quality and safety of care; it did not increase the rate of complications in primary TKR.  Mean length of stay was drastically reduced.  Both patients and care staff were very satisfied with these new procedures.


 LEVEL OF EVIDENCE
 III; case-control study.
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