Protamine-induced condensation of peptide nanofilaments into twisted bundles with controlled helical geometry.Chiral self-assembly of peptides is of fundamental interest in the field of biology and material science.  Protamine, an alkaline biomacromolecule which is ubiquitous in fish and mammalian, plays crucial roles in directing the helical twisting of DNA.  By incorporation with protamine, the micelles condensed with the protamine into large helical bundles with precisely controlled diameter.  Furthermore, to simulate the intracellular environments, we investigated macromolecular crowding on the coassembly of peptide and protamine, which leads to the formation of much thinner helical structures. 
protamine
Protamine-induced condensation of peptide nanofilaments into twisted bundles with controlled helical geometry.Chiral self-assembly of peptides is of fundamental interest in the field of biology and material science.  Protamine, an alkaline biomacromolecule which is ubiquitous in fish and mammalian, plays crucial roles in directing the helical twisting of DNA.  By incorporation with protamine, the micelles condensed with the protamine into large helical bundles with precisely controlled diameter.  Furthermore, to simulate the intracellular environments, we investigated macromolecular crowding on the coassembly of peptide and protamine, which leads to the formation of much thinner helical structures. 
protamine
Protamine-induced condensation of peptide nanofilaments into twisted bundles with controlled helical geometry.Chiral self-assembly of peptides is of fundamental interest in the field of biology and material science.  Protamine, an alkaline biomacromolecule which is ubiquitous in fish and mammalian, plays crucial roles in directing the helical twisting of DNA.  By incorporation with protamine, the micelles condensed with the protamine into large helical bundles with precisely controlled diameter.  Furthermore, to simulate the intracellular environments, we investigated macromolecular crowding on the coassembly of peptide and protamine, which leads to the formation of much thinner helical structures. 
protamine