Naked-Eye Readout of Analyte-Induced NIR Fluorescence Responses by an Initiation-Input-Transduction Nanoplatform.Fluorescence visualization (FV) in the near-infrared (NIR) window promises to break through the signal-to-background ratio (SBR) bottleneck of traditional visible-light-driven FV methods.  However, straightforward NIR-FV has not been realized, owing to the lack of methods to readily transduce NIR responses into instrument-free, naked eye-recognizable outputs.  Now, an initiation-input-transduction platform comprising a well-designed NIR fluorophore as the signal initiator and lanthanide-doped nanocrystals as the transducer for facile NIR-FV is presented.  The analyte-induced off-on NIR signal serves as a sensitizing switch of transducer visible luminescence for naked-eye readout.  By further exploration of initiators, this strategy holds promise to create advanced NIR-FV probes for broad sensing applications.
NIR
Naked-Eye Readout of Analyte-Induced NIR Fluorescence Responses by an Initiation-Input-Transduction Nanoplatform.Fluorescence visualization (FV) in the near-infrared (NIR) window promises to break through the signal-to-background ratio (SBR) bottleneck of traditional visible-light-driven FV methods.  However, straightforward NIR-FV has not been realized, owing to the lack of methods to readily transduce NIR responses into instrument-free, naked eye-recognizable outputs.  Now, an initiation-input-transduction platform comprising a well-designed NIR fluorophore as the signal initiator and lanthanide-doped nanocrystals as the transducer for facile NIR-FV is presented.  The analyte-induced off-on NIR signal serves as a sensitizing switch of transducer visible luminescence for naked-eye readout.  By further exploration of initiators, this strategy holds promise to create advanced NIR-FV probes for broad sensing applications.
NIR
Naked-Eye Readout of Analyte-Induced NIR Fluorescence Responses by an Initiation-Input-Transduction Nanoplatform.Fluorescence visualization (FV) in the near-infrared (NIR) window promises to break through the signal-to-background ratio (SBR) bottleneck of traditional visible-light-driven FV methods.  However, straightforward NIR-FV has not been realized, owing to the lack of methods to readily transduce NIR responses into instrument-free, naked eye-recognizable outputs.  Now, an initiation-input-transduction platform comprising a well-designed NIR fluorophore as the signal initiator and lanthanide-doped nanocrystals as the transducer for facile NIR-FV is presented.  The analyte-induced off-on NIR signal serves as a sensitizing switch of transducer visible luminescence for naked-eye readout.  By further exploration of initiators, this strategy holds promise to create advanced NIR-FV probes for broad sensing applications.
NIR