Global Transcriptome Characterization and Assembly of the Thermophilic Ascomycete Chaetomium thermophilum.A correct genome annotation is fundamental for research in the field of molecular and structural biology.  The annotation of the reference genome of Chaetomium thermophilum has been reported previously, but it is essentially limited to open reading frames (ORFs) of protein coding genes and contains only a few noncoding transcripts.  In this study, we identified and annotated full-length transcripts of C. thermophilum by deep RNA sequencing.  Furthermore, we substantially extended the Gene Ontology (GO) and Enzyme Commission (EC) lists, which provide comprehensive search tools for potential industrial applications and basic research.  The identified novel transcripts and improved annotation will help to understand the gene regulatory landscape in C. thermophilum. 
THERM