In-silico degradation pattern of ponatinib was outlined by using Zeneth software. 
Zeneth
Additionally, toxicity and mutagenicity profiles of ponatinib and its degradation impurities were predicted in-silico by using DEREK and SARAH software. 
DEREK
Additionally, toxicity and mutagenicity profiles of ponatinib and its degradation impurities were predicted in-silico by using DEREK and SARAH software. 
SARAH