Use of MarginProbe as an adjunct to standard operating procedure does not significantly reduce re-excision rates in breast conserving surgery.PURPOSE
 MarginProbe is a device that provides real-time evaluation of lumpectomy margins during surgery.  The aim of this study was to evaluate the impact of MarginProbe as an adjunct to standard operating procedure (SOP).


 Patients diagnosed with breast cancer scheduled for breast conserving surgery were consented for intraoperative use of MarginProbe.  Based on 360 measurement sites, MarginProbe demonstrated a sensitivity of 67% and specificity of 60%, with a positive predictive value of 16%, and of negative predictive value of 94%, which was similar to the accuracy of SOP.


 MarginProbe performs equally as well as specimen radiography and gross pathologic examination.  In this setting where the baseline re-excision rate was low, the use of MarginProbe as an adjunct to SOP resulted in a small 2% absolute reduction in re-excision rate.
MarginProbe
Use of MarginProbe as an adjunct to standard operating procedure does not significantly reduce re-excision rates in breast conserving surgery.PURPOSE
 MarginProbe is a device that provides real-time evaluation of lumpectomy margins during surgery.  The aim of this study was to evaluate the impact of MarginProbe as an adjunct to standard operating procedure (SOP).


 Patients diagnosed with breast cancer scheduled for breast conserving surgery were consented for intraoperative use of MarginProbe.  Based on 360 measurement sites, MarginProbe demonstrated a sensitivity of 67% and specificity of 60%, with a positive predictive value of 16%, and of negative predictive value of 94%, which was similar to the accuracy of SOP.


 MarginProbe performs equally as well as specimen radiography and gross pathologic examination.  In this setting where the baseline re-excision rate was low, the use of MarginProbe as an adjunct to SOP resulted in a small 2% absolute reduction in re-excision rate.
MarginProbe
Use of MarginProbe as an adjunct to standard operating procedure does not significantly reduce re-excision rates in breast conserving surgery.PURPOSE
 MarginProbe is a device that provides real-time evaluation of lumpectomy margins during surgery.  The aim of this study was to evaluate the impact of MarginProbe as an adjunct to standard operating procedure (SOP).


 Patients diagnosed with breast cancer scheduled for breast conserving surgery were consented for intraoperative use of MarginProbe.  Based on 360 measurement sites, MarginProbe demonstrated a sensitivity of 67% and specificity of 60%, with a positive predictive value of 16%, and of negative predictive value of 94%, which was similar to the accuracy of SOP.


 MarginProbe performs equally as well as specimen radiography and gross pathologic examination.  In this setting where the baseline re-excision rate was low, the use of MarginProbe as an adjunct to SOP resulted in a small 2% absolute reduction in re-excision rate.
MarginProbe