FABIAN-variant: predicting the effects of DNA variants on transcription factor binding.While great advances in predicting the effects of coding variants have been made, the assessment of non-coding variants remains challenging.  Our new web-based application FABIAN-variant uses 1224 TFFMs and 3790 PWMs to predict whether and to which degree DNA variants affect the binding of 1387 different human transcription factors.  FABIAN-variant is available freely at https://www.genecascade.org/fabian/.
FABIAN-variant
FABIAN-variant: predicting the effects of DNA variants on transcription factor binding.While great advances in predicting the effects of coding variants have been made, the assessment of non-coding variants remains challenging.  Our new web-based application FABIAN-variant uses 1224 TFFMs and 3790 PWMs to predict whether and to which degree DNA variants affect the binding of 1387 different human transcription factors.  FABIAN-variant is available freely at https://www.genecascade.org/fabian/.
FABIAN-variant
The software is written in C++ for speed but variants can be entered through a web interface. 
C++