A plasmonic nanoledge array sensor for detection of anti-insulin antibodies of type 1 diabetes biomarker.Here we present a plasmonic nanoledge device with high sensitivity and selectivity used to detect protein biomarkers simply by functionalizing the device, which specifically binds to particular biomolecule or biomarkers. 
plasmonic nanoledge array sensor
A plasmonic nanoledge array sensor for detection of anti-insulin antibodies of type 1 diabetes biomarker.Here we present a plasmonic nanoledge device with high sensitivity and selectivity used to detect protein biomarkers simply by functionalizing the device, which specifically binds to particular biomolecule or biomarkers.  We employ this plasmonic nanoledge device for the detection of anti-insulin antibodies of type 1 diabetes (T1D) in buffer and human serum at the range of pg ml-1 to 100 ng ml-1. 
plasmonic nanoledge device
The signal transduction is based on the extraordinary optical transmission (EOT) through the nanoledge array and the optical spectral changes with the biological binding reaction between the surface functionalized insulin with anti-insulin antibody. 
extraordinary optical transmission (EOT)
A plasmonic nanoledge array sensor for detection of anti-insulin antibodies of type 1 diabetes biomarker.Here we present a plasmonic nanoledge device with high sensitivity and selectivity used to detect protein biomarkers simply by functionalizing the device, which specifically binds to particular biomolecule or biomarkers.  The signal transduction is based on the extraordinary optical transmission (EOT) through the nanoledge array and the optical spectral changes with the biological binding reaction between the surface functionalized insulin with anti-insulin antibody. 
nanoledge array