Mosaicism in CRISPR/Cas9-mediated genome editing.The CRISPR/Cas9 system is a rapid, simple, and often extremely efficient gene editing method.  This is especially the case when the CRISPR/Cas9 system is used in embryos.  Here we review the pros and cons of mosaic mutations of gene-edited animals caused by using the CRISPR/Cas9 system in embryos.  Furthermore, we will discuss the mechanisms underlying mosaic mutations resulting from the CRISPR/Cas9 system, as well as the possible strategies for reducing mosaicism.  By developing ways to overcome mosaic mutations when using CRISPR/Cas9, genotyping for germline gene disruptions should become more reliable. 
CRISPR/Cas9
Mosaicism in CRISPR/Cas9-mediated genome editing.The CRISPR/Cas9 system is a rapid, simple, and often extremely efficient gene editing method.  This is especially the case when the CRISPR/Cas9 system is used in embryos.  Here we review the pros and cons of mosaic mutations of gene-edited animals caused by using the CRISPR/Cas9 system in embryos.  Furthermore, we will discuss the mechanisms underlying mosaic mutations resulting from the CRISPR/Cas9 system, as well as the possible strategies for reducing mosaicism.  By developing ways to overcome mosaic mutations when using CRISPR/Cas9, genotyping for germline gene disruptions should become more reliable. 
CRISPR/Cas9
Mosaicism in CRISPR/Cas9-mediated genome editing.The CRISPR/Cas9 system is a rapid, simple, and often extremely efficient gene editing method.  This is especially the case when the CRISPR/Cas9 system is used in embryos.  Here we review the pros and cons of mosaic mutations of gene-edited animals caused by using the CRISPR/Cas9 system in embryos.  Furthermore, we will discuss the mechanisms underlying mosaic mutations resulting from the CRISPR/Cas9 system, as well as the possible strategies for reducing mosaicism.  By developing ways to overcome mosaic mutations when using CRISPR/Cas9, genotyping for germline gene disruptions should become more reliable. 
CRISPR/Cas9
Mosaicism in CRISPR/Cas9-mediated genome editing.The CRISPR/Cas9 system is a rapid, simple, and often extremely efficient gene editing method.  This is especially the case when the CRISPR/Cas9 system is used in embryos.  Here we review the pros and cons of mosaic mutations of gene-edited animals caused by using the CRISPR/Cas9 system in embryos.  Furthermore, we will discuss the mechanisms underlying mosaic mutations resulting from the CRISPR/Cas9 system, as well as the possible strategies for reducing mosaicism.  By developing ways to overcome mosaic mutations when using CRISPR/Cas9, genotyping for germline gene disruptions should become more reliable. 
CRISPR/Cas9
Mosaicism in CRISPR/Cas9-mediated genome editing.The CRISPR/Cas9 system is a rapid, simple, and often extremely efficient gene editing method.  This is especially the case when the CRISPR/Cas9 system is used in embryos.  Here we review the pros and cons of mosaic mutations of gene-edited animals caused by using the CRISPR/Cas9 system in embryos.  Furthermore, we will discuss the mechanisms underlying mosaic mutations resulting from the CRISPR/Cas9 system, as well as the possible strategies for reducing mosaicism.  By developing ways to overcome mosaic mutations when using CRISPR/Cas9, genotyping for germline gene disruptions should become more reliable. 
CRISPR/Cas9