Hyperthermia Improves Solubility of Intravesical Chemotherapeutic Agents.BACKGROUND
 Hyperthermia is frequently used as an adjunct to intravesical chemotherapy to improve drug delivery and response to treatment.


 Drugs were assessed at room temperature (23°C), body temperature (37°C), and 43°C, the temperature used for hyperthermic intravesical treatments.  Hyperthermia as an adjunct to intravesical treatment would improve drug solubility, and likely drug delivery as some current regimens are insoluble without heat. 
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