CRISPR Screens in Synthetic Lethality and Combinatorial Therapies for Cancer.Cancer is a complex disease resulting from the accumulation of genetic dysfunctions.  The state of the art to find new genetic interactions are currently large-scale forward genetic CRISPR screens.  CRISPR technology has rapidly evolved to be a common tool in the vast majority of laboratories, as tools to implement CRISPR screen protocols are available to all researchers.  This review explores the CRISPR screen methodology, integrates the up-to-date published findings on CRISPR screens in the cancer field and proposes future directions to uncover cancer regulation and individual responses to chemotherapy.
CRISPR
CRISPR Screens in Synthetic Lethality and Combinatorial Therapies for Cancer.Cancer is a complex disease resulting from the accumulation of genetic dysfunctions.  The state of the art to find new genetic interactions are currently large-scale forward genetic CRISPR screens.  CRISPR technology has rapidly evolved to be a common tool in the vast majority of laboratories, as tools to implement CRISPR screen protocols are available to all researchers.  This review explores the CRISPR screen methodology, integrates the up-to-date published findings on CRISPR screens in the cancer field and proposes future directions to uncover cancer regulation and individual responses to chemotherapy.
CRISPR
CRISPR Screens in Synthetic Lethality and Combinatorial Therapies for Cancer.Cancer is a complex disease resulting from the accumulation of genetic dysfunctions.  The state of the art to find new genetic interactions are currently large-scale forward genetic CRISPR screens.  CRISPR technology has rapidly evolved to be a common tool in the vast majority of laboratories, as tools to implement CRISPR screen protocols are available to all researchers.  This review explores the CRISPR screen methodology, integrates the up-to-date published findings on CRISPR screens in the cancer field and proposes future directions to uncover cancer regulation and individual responses to chemotherapy.
CRISPR
CRISPR Screens in Synthetic Lethality and Combinatorial Therapies for Cancer.Cancer is a complex disease resulting from the accumulation of genetic dysfunctions.  The state of the art to find new genetic interactions are currently large-scale forward genetic CRISPR screens.  CRISPR technology has rapidly evolved to be a common tool in the vast majority of laboratories, as tools to implement CRISPR screen protocols are available to all researchers.  This review explores the CRISPR screen methodology, integrates the up-to-date published findings on CRISPR screens in the cancer field and proposes future directions to uncover cancer regulation and individual responses to chemotherapy.
CRISPR