The Brazilian compound library (BraCoLi) database: a repository of chemical and biological information for drug design.The Brazilian Compound Library (BraCoLi) is a novel open access and manually curated electronic library of compounds developed by Brazilian research groups to support further computer-aided drug design works, available on https://www.farmacia.ufmg.br/qf/downloads/ .  Also, the chemical diversity and drug-like profiles of BraCoLi were defined to analyze its chemical space.  A comparison using principal component analysis showed that BraCoLi is similar to other databases (FDA-approved drugs and NuBBEDB) regarding structural and physicochemical patterns.  Furthermore, a scaffold analysis showed that BraCoLi presents several privileged chemical skeletons with great diversity.  Despite the similar distribution in the structural and physicochemical spaces, Tanimoto coefficient values indicated that compounds present in the BraCoLi are generally different from the two other databases, where they showed different kernel distributions and low similarity. 
BraCoLi
The Brazilian compound library (BraCoLi) database: a repository of chemical and biological information for drug design.The Brazilian Compound Library (BraCoLi) is a novel open access and manually curated electronic library of compounds developed by Brazilian research groups to support further computer-aided drug design works, available on https://www.farmacia.ufmg.br/qf/downloads/ .  Also, the chemical diversity and drug-like profiles of BraCoLi were defined to analyze its chemical space.  A comparison using principal component analysis showed that BraCoLi is similar to other databases (FDA-approved drugs and NuBBEDB) regarding structural and physicochemical patterns.  Furthermore, a scaffold analysis showed that BraCoLi presents several privileged chemical skeletons with great diversity.  Despite the similar distribution in the structural and physicochemical spaces, Tanimoto coefficient values indicated that compounds present in the BraCoLi are generally different from the two other databases, where they showed different kernel distributions and low similarity. 
BraCoLi
A comparison using principal component analysis showed that BraCoLi is similar to other databases (FDA-approved drugs and NuBBEDB) regarding structural and physicochemical patterns. 
NuBBEDB
A comparison using principal component analysis showed that BraCoLi is similar to other databases (FDA-approved drugs and NuBBEDB) regarding structural and physicochemical patterns. 
FDA-approved drugs