PWV can be non-invasively assessed using magnetic resonance imaging (MRI).  The aortic length is calculated using a multi-slice 3D scan and the transit time is computed using a 2D velocity encoded MRI (VE) scan.  We proposed and evaluated a fully automatic method to calculate the PWV on a large set of multi-center MRI scans. 
MRI
For each subject a multi-slice 3D scan of the aorta was acquired in an oblique-sagittal plane and a 2D VE scan acquired in a transverse plane cutting through the proximal ascending and descending aorta.  (ii) an algorithm that delineates the proximal ascending and descending aorta from the time-resolved 2D VE scan and subsequently obtains the velocity-time flow curves was also developed, and 
VE scan
For this study 212 subjects were retrospectively selected from a large multi-center heart-brain connection cohort. 
multi-center heart-brain connection cohort