Association of Telomere Length and Serum Vitamin D Levels with Type 2 Diabetes Mellitus and its Related Complications: A Possible Future Perspective.Evidence show that shortened telomere length (TL) and low Vitamin D levels can increase the risk of type 2 diabetes mellitus (T2DM) and its associated complications.  T2DM has been considered as an age-related disease, it may be associated with TL.  This 1-year cross-sectional study was conducted at a tertiary care hospital on 90 patients.  Height, weight, body mass index, waist-hip ratio was calculated.  Fasting blood sugars, postprandial blood sugar, and glycated hemoglobin (HbA1c) were analyzed.  Absolute TL was obtained from quantitative real-time polymerase chain reaction (qPCR).  Descriptive analysis of the data was done using R i386 3.6.3.  The study found a positive correlation between TL and Vitamin D levels (r = 0.64; P < 0.0001).  The interaction with high HbA1c levels and lower levels of Vitamin D led to the shortening of TL (P = 0.0001).  The median of TL and mean of Vitamin D levels were significantly less in the diabetic group (P < 0.0001).  Vitamin D levels positively affected the TL and its levels had an inverse relation with the HbA1c levels.  This association had a significant effect on the shortening of TL.  Vitamin D also had a significant association with other diabetic complications that instigated the shortening of TL.  Therefore, assessing the role of Vitamin D levels on the shortening of TL can prove to be crucial biomarkers in managing optimal glycemic levels in T2DM patients.
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Descriptive analysis of the data was done using R i386 3.6.3. 
R i386 3.6.3