Stellate Ganglion Block Improves Postoperative Sleep Quality and Analgesia in Patients with Breast Cancer: A Randomized Controlled Trial.INTRODUCTION
 Postoperative impaired sleep quality and pain are associated with adverse outcomes.  Stellate ganglion block (SGB) has shown promising results in enhancing sleep quality and alleviating neuropathic pain.  This study aimed to investigate the effects of ultrasound-guided SGB on postoperative sleep quality and pain in patients undergoing breast cancer surgery.


 This study is a parallel-group randomized controlled clinical trial with two groups: SGB and control.  Fifty female patients undergoing breast cancer surgery were randomized in a 1:1 ratio to receive preoperative ultrasound-guided single-injection SGB (SGB group) or just an ultrasound scan (control group).  All participants were blinded to the group assignment.  The primary outcome was postoperative sleep quality, assessed by the St. Mary's Hospital Sleep Questionnaire and actigraphy 2 days postoperatively.  The secondary outcome was postoperative pain, measured by the visual analog scale.


 A total of 48 patients completed the study, with 23 patients in the control group and 25 in the SGB group.  The postoperative St. Mary's Hospital Sleep Questionnaire scores were significantly higher in the SGB group than in the control group on 1 day postoperative (30.88 ± 2.44 versus 27.35 ± 4.12 points, P = 0.001).  The SGB also increased the total sleep time and sleep efficiency (main actigraphy indicators) during the first two postoperative nights.  Compared with the control group, preoperative SGB reduced postoperative pain and the incidence of breast cancer-related lymphedema (20% versus 52.2%, P = 0.02, odds ratio 0.229, 95% confidence interval 0.064-0.821).  CONCLUSION
 Preoperative ultrasound-guided SGB improves postoperative sleep quality and analgesia in patients undergoing breast cancer surgery.  SGB may be a safe and practical treatment to enhance the postoperative quality of life in patients with breast cancer.


 The study was registered in the Chinese Clinical Trial Registry (ChiCTR2100046620, principal investigator: Kai Zeng, date of registration: 23 May 2021).
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Stellate Ganglion Block Improves Postoperative Sleep Quality and Analgesia in Patients with Breast Cancer: A Randomized Controlled Trial.INTRODUCTION
 Stellate ganglion block (SGB) has shown promising results in enhancing sleep quality and alleviating neuropathic pain. 
Stellate Ganglion Block