Identification of Hanks-Type Kinase PknB-Specific Targets in the Streptococcus thermophilus Phosphoproteome.Protein phosphorylation especially on serine/threonine/tyrosine residues are frequent in many bacteria.  The objective of our work was to establish the first phosphoproteome of Streptococcus thermophilus, a lactic acid bacterium widely used in dairy fermentations in order to identified the proteins and pathways tagged by Ser/Thr/Tyr phosphorylations.  In addition, we have evaluated the role in this process of the only Hanks-type kinase encoded in the S. thermophilus genome.  We have constructed a mutant defective for the Hanks type kinase in S. thermophilus and established the proteomes and phosphoproteomes of the wild type and the mutant strains. 
THERM