Oxidized alginic acid, dopamine, and antimicrobial peptide ε-polylysine were used to prepare a nanocomposite (ODP), and then further cross-linked with acrylamide to fabricate a nanocomposite hydrogel (ODPA).  ODPA hydrogel can adhere to the surface of bleeding organs and arrest bleeding within 30 s.  Compared with commercial alginate sponge, ODPA hydrogel can accelerate the healing of infected full-thickness wound by reducing inflammation, promoting angiogenesis, and collagen deposition. 
ODP
Oxidized alginic acid, dopamine, and antimicrobial peptide ε-polylysine were used to prepare a nanocomposite (ODP), and then further cross-linked with acrylamide to fabricate a nanocomposite hydrogel (ODPA).  ODPA hydrogel can adhere to the surface of bleeding organs and arrest bleeding within 30 s.  Compared with commercial alginate sponge, ODPA hydrogel can accelerate the healing of infected full-thickness wound by reducing inflammation, promoting angiogenesis, and collagen deposition. 
ODPA