A SIMEX approach for meta-analysis of diagnostic accuracy studies with attention to ROC curves.Bivariate random-effects models represent an established approach for meta-analysis of accuracy measures of a diagnostic test, which are typically given by sensitivity and specificity.  The proposed alternative is a simulation-extrapolation method, called SIMEX, developed within the measurement error literature.  SIMEX reveals a satisfactory strategy, providing more accurate inferential results if compared to the likelihood approach, while avoiding convergence failure. 
SIMEX