An approach for long-term, multi-probe Neuropixels recordings in unrestrained rats.The use of Neuropixels probes for chronic neural recordings is in its infancy and initial studies leave questions about long-term stability and probe reusability unaddressed.  Here, we demonstrate a new approach for chronic Neuropixels recordings over a period of months in freely moving rats.  We conclude that cost-effective, multi-region, and multi-probe Neuropixels recordings can be carried out with high yields over multiple months in rats or other similarly sized animals.  Our methods and observations may facilitate the standardization of chronic recording from Neuropixels probes in freely moving animals.
Neuropixels
An approach for long-term, multi-probe Neuropixels recordings in unrestrained rats.The use of Neuropixels probes for chronic neural recordings is in its infancy and initial studies leave questions about long-term stability and probe reusability unaddressed.  Here, we demonstrate a new approach for chronic Neuropixels recordings over a period of months in freely moving rats.  We conclude that cost-effective, multi-region, and multi-probe Neuropixels recordings can be carried out with high yields over multiple months in rats or other similarly sized animals.  Our methods and observations may facilitate the standardization of chronic recording from Neuropixels probes in freely moving animals.
Neuropixels