Remimazolam, the soft benzodiazepine analogue, is at an advanced stage of development, having already received regulatory approval or review in several countries.



remimazolam
Soft drug development programs for propranadid, etomidate, and benzodiazepine analogues have been undertaken in recent years.  Although all three drugs advanced into human trials, neuro-excitatory adverse effects hampered the propranadid and etomidate analogue projects. 
propranadid
Soft drug development programs for propranadid, etomidate, and benzodiazepine analogues have been undertaken in recent years.  Although all three drugs advanced into human trials, neuro-excitatory adverse effects hampered the propranadid and etomidate analogue projects. 
etomidate
Soft drug development programs for propranadid, etomidate, and benzodiazepine analogues have been undertaken in recent years. 
benzodiazepine analogues
Soft drugs in anesthesia: remifentanil as prototype to modern anesthetic drug development.PURPOSE OF REVIEW
 With succinylcholine as the historical forerunner and remifentanil as the modern prototype, the soft drug paradigm continues to hold promise for the future of anesthesia drug development.
remifentanil