RBM20 and RBM24 cooperatively promote the expression of short enh splice variants.PDZ-LIM protein ENH1 is a scaffold protein for protein kinases and transcriptional regulators.  Here, we found that two splicing factors, RNA-binding motif 20 (RBM20) and RNA-binding motif 24 (RBM24) together promoted the expression of short enh splice variants and bound the 5' intronic region of exon 11 containing an in-phase stop codon.  Collectively, our results suggest that, in healthy conditions, RBM20 and RBM24 cooperate to promote the expression of short ENH isoforms.
RBM20
RBM20 and RBM24 cooperatively promote the expression of short enh splice variants.PDZ-LIM protein ENH1 is a scaffold protein for protein kinases and transcriptional regulators.  Here, we found that two splicing factors, RNA-binding motif 20 (RBM20) and RNA-binding motif 24 (RBM24) together promoted the expression of short enh splice variants and bound the 5' intronic region of exon 11 containing an in-phase stop codon.  Collectively, our results suggest that, in healthy conditions, RBM20 and RBM24 cooperate to promote the expression of short ENH isoforms.
RBM24
RBM20 and RBM24 cooperatively promote the expression of short enh splice variants.PDZ-LIM protein ENH1 is a scaffold protein for protein kinases and transcriptional regulators.  While ENH1 promotes the hypertrophic growth of cardiomyocytes, its short splice variant (ENH3) prevents the hypertrophic growth. 
ENH1
While ENH1 promotes the hypertrophic growth of cardiomyocytes, its short splice variant (ENH3) prevents the hypertrophic growth. 
ENH3