AutismKB 2.0: a knowledgebase for the genetic evidence of autism spectrum disorder.Autism spectrum disorder (ASD) is a complex neurodevelopmental disorder with strong genetic contributions.  To provide a comprehensive resource for the genetic evidence of ASD, we have updated the Autism KnowledgeBase (AutismKB) to version 2.0.  AutismKB 2.0 integrates multiscale genetic data on 1379 genes, 5420 copy number variations and structural variations, 11 669 single-nucleotide variations or small insertions/deletions (SNVs/indels) and 172 linkage regions.  In particular, AutismKB 2.0 highlights 5669 de novo SNVs/indels due to their significant contribution to ASD genetics and includes 789 mosaic variants due to their recently discovered contributions to ASD pathogenesis.  AutismKB 2.0 is freely available and can be a valuable resource for researchers.
AutismKB