For this purpose, the three-dimensional tertiary structure of the α-glucosidase was generated by using the Molecular Operating Environment (MOE).  The molecular docking of 37 alkaloids along with standard acarbose and miglitol reported as a α-glucosidase inhibitor was performed via MOE-Dock implemented in MOE software to find the binding modes of these inhibitors. 
MOE
The generated model was then validated by using the RAMPAGE and ERRAT server. 
RAMPAGE
The generated model was then validated by using the RAMPAGE and ERRAT server. 
ERRAT server
The molecular docking of 37 alkaloids along with standard acarbose and miglitol reported as a α-glucosidase inhibitor was performed via MOE-Dock implemented in MOE software to find the binding modes of these inhibitors. 
MOE-Dock implemented in MOE software