findGSE: estimating genome size variation within human and Arabidopsis using k-mer frequencies.Motivation
 We present findGSE, which fits skew normal distributions to k-mer frequencies to estimate GS.  findGSE outperformed existing tools in an extensive simulation study.  Estimating GSs of 89 Arabidopsis thaliana accessions, findGSE showed the highest capability in capturing GS variations.  In an application with 71 female and 71 male human individuals, findGSE delivered an average of 3039 Mb as haploid human GS, while female genomes were on average 41 Mb larger than male genomes, in astonishing agreement with size difference of the X and Y chromosomes.  R package of findGSE is freely available at https://github.com/schneebergerlab/findGSE and supported on linux and Mac systems.



findGSE
R package of findGSE is freely available at https://github.com/schneebergerlab/findGSE and supported on linux and Mac systems.



R package of findGSE