Single-cell analyses of transcriptional heterogeneity during drug tolerance transition in cancer cells by RNA sequencing.The acute cellular response to stress generates a subpopulation of reversibly stress-tolerant cells under conditions that are lethal to the majority of the population. 
RNA sequencing
We performed whole transcriptome sequencing analyses of metastatic human breast cancer cells subjected to the chemotherapeutic agent paclitaxel at the single-cell and population levels. 
paclitaxel