Study of the cardiotoxicity of Venenum Bufonis in rats using an 1H NMR-based metabolomics approach.Venenum Bufonis, a well-known traditional Chinese medicine, has been widely used in Asia and has gained popularity in Western countries over the last decade.  In this work, the cardiotoxicity of Venenum Bufonis was investigated using a 11H NMR-based metabolomics approach.  The 1H NMR profiles of the serum, myocardial extracts and liver extracts of specific-pathogen-free rats showed that Venenum Bufonis produced significant metabolic perturbations dose-dependently with a distinct time effect, peaking at 2 hr after dosing and attenuating gradually. 
1H NMR
Study of the cardiotoxicity of Venenum Bufonis in rats using an 1H NMR-based metabolomics approach.Venenum Bufonis, a well-known traditional Chinese medicine, has been widely used in Asia and has gained popularity in Western countries over the last decade.  In this work, the cardiotoxicity of Venenum Bufonis was investigated using a 11H NMR-based metabolomics approach. 
1H NMR-based metabolomics approach