Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9.Xenotransplantation is a promising strategy to alleviate the shortage of organs for human transplantation.  Using CRISPR-Cas9, we inactivated all of the PERVs in a porcine primary cell line and generated PERV-inactivated pigs via somatic cell nuclear transfer. 
CRISPR-Cas9
Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9.Xenotransplantation is a promising strategy to alleviate the shortage of organs for human transplantation.  Using CRISPR-Cas9, we inactivated all of the PERVs in a porcine primary cell line and generated PERV-inactivated pigs via somatic cell nuclear transfer. 
CRISPR-Cas9
Inactivation of porcine endogenous retrovirus in pigs using CRISPR-Cas9.Xenotransplantation is a promising strategy to alleviate the shortage of organs for human transplantation.  Using CRISPR-Cas9, we inactivated all of the PERVs in a porcine primary cell line and generated PERV-inactivated pigs via somatic cell nuclear transfer. 
CRISPR-Cas9