Periodic benefit-risk assessment using Bayesian stochastic multi-criteria acceptability analysis.Benefit-risk (BR) assessment is essential to ensure the best decisions are made for a medical product in the clinical development process, regulatory marketing authorization, post-market surveillance, and coverage and reimbursement decisions. 
Bayesian stochastic multi-criteria acceptability analysis
In this paper, we propose a general statistical framework for periodic benefit-risk assessment, in which Bayesian meta-analysis and stochastic multi-criteria acceptability analysis (SMAA) will be combined to synthesize the accumulating evidence. 
Bayesian meta-analysis