An automated breast volume scanner was used to acquire ultrasound images of the breast as it was gently compressed. 
ultrasound images
Cross-correlation between successive images was used to determine the displacement within the tissue. 
cross-correlation
Improving three-dimensional mechanical imaging of breast lesions with principal component analysis.PURPOSE
 The resulting displacement field was filtered of all but compressive motion through principal component analysis. 
principal component analysis
This displacement field was used to infer spatial distribution of shear modulus by solving a 3D elastic inverse problem.



3D elastic inverse problem