Vitamin D receptor signaling and its therapeutic implications: Genome-wide and structural view.Vitamin D3 is one of the few natural compounds that has, via its metabolite 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) and the transcription factor vitamin D receptor (VDR), a direct effect on gene regulation. 
Vitamin D3
Vitamin D receptor signaling and its therapeutic implications: Genome-wide and structural view.Vitamin D3 is one of the few natural compounds that has, via its metabolite 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) and the transcription factor vitamin D receptor (VDR), a direct effect on gene regulation. 
1α,25-dihydroxyvitamin D3 (1,25(OH)2D3)
Vitamin D receptor signaling and its therapeutic implications: Genome-wide and structural view.Vitamin D3 is one of the few natural compounds that has, via its metabolite 1α,25-dihydroxyvitamin D3 (1,25(OH)2D3) and the transcription factor vitamin D receptor (VDR), a direct effect on gene regulation. 
Vitamin D receptor (VDR)
For efficiently applying the therapeutic and disease-preventing potential of 1,25(OH)2D3 and its synthetic analogs, the key steps in vitamin D signaling need to be understood.  This review will present the latest genome-wide insight into vitamin D signaling, and will discuss its therapeutic implications.
Vitamin D signaling