The system consists of a 3D culture unit and a medium perfusion unit.  The 3D culture unit is dedicated for spheroid culture without using scaffolds, eliminating concerns about biocompatibility of artificial materials. 
3D culture unit
The system consists of a 3D culture unit and a medium perfusion unit. 
medium perfusion unit
The spheroids are cultured in a sealed environment and their life are sustained by hollow fiber perfusion fluidics. 
hollow fiber perfusion fluidics