Here, we discuss the use of vertex models to study the morphogenesis of epithelial tissues.  We provide an introduction to the theoretical foundation of vertex models and describe how they can integrate mechanical and biochemical dynamics.  Finally, we review recent advances in the application of vertex models to investigate dorsal closure, a morphogenetic process in the Drosophila embryo with parallels to both embryonic development and wound repair in vertebrate organisms.
vertex models
Here, we discuss the use of vertex models to study the morphogenesis of epithelial tissues.  We provide an introduction to the theoretical foundation of vertex models and describe how they can integrate mechanical and biochemical dynamics.  Finally, we review recent advances in the application of vertex models to investigate dorsal closure, a morphogenetic process in the Drosophila embryo with parallels to both embryonic development and wound repair in vertebrate organisms.
vertex models
Here, we discuss the use of vertex models to study the morphogenesis of epithelial tissues.  We provide an introduction to the theoretical foundation of vertex models and describe how they can integrate mechanical and biochemical dynamics.  Finally, we review recent advances in the application of vertex models to investigate dorsal closure, a morphogenetic process in the Drosophila embryo with parallels to both embryonic development and wound repair in vertebrate organisms.
vertex models