Hypothermia improves outcomes and is the current standard of care.  Yet, clinical trials suggest that 44-53% of infants who receive hypothermia will die or suffer moderate to severe neurological disability.  However, several on-going trials will provide much needed data regarding the safety and efficacy of this potential new therapy when given in conjunction with hypothermia for HIE.  High-dose EPO is a promising therapy that can be administered in conjunction with hypothermia. 
THERM