Kikuchi-Fujimoto disease in children: two case reports and a review of the literature.BACKGROUND
 Kikuchi-Fujimoto disease is a rare, idiopathic and generally self-limiting cause of lymphadenitis of unknow etiology with a low recurrence rate. 
Kikuchi-Fujimoto disease
Here we describe two case reports of Kikuchi Fujimoto disease presenting in Milan within the space of a few months. 
Kikuchi Fujimoto disease
The first involved the recurrence of KFD in a young boy from Sri Lanka; the second was a rare case of severe KFD complicated by HLH.


 Pediatricians must consider KFD in the differential diagnosis of fever of unknown origin in children, even in western countries.  Where symptoms suggest KFD, a systematic diagnostic approach is key.  Since no guidelines on the management of KFD are available, further studies should be conducted to investigate the therapeutic options and long term outcome in children.
KFD
The first involved the recurrence of KFD in a young boy from Sri Lanka; the second was a rare case of severe KFD complicated by HLH.


 Pediatricians must consider KFD in the differential diagnosis of fever of unknown origin in children, even in western countries.  Where symptoms suggest KFD, a systematic diagnostic approach is key.  Since no guidelines on the management of KFD are available, further studies should be conducted to investigate the therapeutic options and long term outcome in children.
KFD
The first involved the recurrence of KFD in a young boy from Sri Lanka; the second was a rare case of severe KFD complicated by HLH.


 Pediatricians must consider KFD in the differential diagnosis of fever of unknown origin in children, even in western countries.  Where symptoms suggest KFD, a systematic diagnostic approach is key.  Since no guidelines on the management of KFD are available, further studies should be conducted to investigate the therapeutic options and long term outcome in children.
KFD