Guiding principles for use of newer biologics and bronchial thermoplasty for patients with severe asthma.BACKGROUND
 Furthermore, current guidelines do not address a clear, practical approach to treatment that is based on a patient's asthma phenotype.


 To develop a consensus on the definition of severe asthma, the role of biomarkers and phenotyping severe asthma, and the use of newer biologic therapies and bronchial thermoplasty to help guide practicing clinicians.


 We describe a consensus on the definition of severe asthma, asthma phenotyping with the use of available biomarkers, and guiding principles for newer biologic therapies and bronchial thermoplasty.



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