Gaussian Markov transition models of molecular kinetics.The slow processes of molecular dynamics (MD) simulations--governed by dominant eigenvalues and eigenfunctions of MD propagators--contain essential information on structures of and transition rates between long-lived conformations. 
Gaussian Markov transition models
Existing approaches to this problem, including Markov state models and the variational approach, represent the dominant eigenfunctions as linear combinations of a set of basis functions. 
Markov state models
Existing approaches to this problem, including Markov state models and the variational approach, represent the dominant eigenfunctions as linear combinations of a set of basis functions. 
the variational approach