Development of a CCK1R-membrane nanoparticle as a fish-out tool for bioactive peptides.The cholecystokinin receptor type 1 (CCK1R) is a G protein-coupled receptor (GPCR) that is involved in several biological processes including the regulation of the secretion of digestive enzymes. 
CCK1R-membrane nanoparticle
Functional expressed CCK1R is reconstituted into membrane nanoparticles called NABBs (nanoscale apo-lipoprotein bound bilayers). 
NABBs (nanoscale apo-lipoprotein bound bilayers)
Development of a CCK1R-membrane nanoparticle as a fish-out tool for bioactive peptides.The cholecystokinin receptor type 1 (CCK1R) is a G protein-coupled receptor (GPCR) that is involved in several biological processes including the regulation of the secretion of digestive enzymes.  NABBs are native-like bilayer membrane systems for incorporation of GPCRs. 
GPCR
CCK1R-NABBs were characterized using a fluorescently labeled CCK analog and can be used as a cutting-edge technology to screen for CCK1R ligands using affinity-selection mass spectrometry.
CCK1R-NABBs