Electrografted diazonium salt layers for antifouling on the surface of surface plasmon resonance biosensors.Electrografted diazonium salt layers on the surface of surface plasmon resonance (SPR) sensors present potential for a significant improvement in antifouling coatings.  Instead of using empirical and rough estimated values, the penetration depth and sensitivity of the SPR instrument were experimentally determined for the calculation of nonspecific adsorption surface coverage.  This provides a method to better examine antifouling surface coatings and compare crossing different coatings and experimental systems.  Direct comparison of antifouling performance of different diazonium salts was facilitated by a tripad SPR sensor design. 
SPR
Instead of using empirical and rough estimated values, the penetration depth and sensitivity of the SPR instrument were experimentally determined for the calculation of nonspecific adsorption surface coverage. 
SPR instrument
Direct comparison of antifouling performance of different diazonium salts was facilitated by a tripad SPR sensor design. 
SPR sensor design