Double Dose Versus Standard Dose Hepatitis B Vaccine in HIV-infected Children: A Randomized Controlled Trial.OBJECTIVE
 To compare the efficacy of double dose (20 µg) with standard dose (10 µg) of hepatitis B vaccine in HIV-infected children.


 Unvaccinated HIV-infected children were randomized to receive 3 doses of double dose (N=27) or standard dose (N=28) of recombinant Hepatitis B vaccine.  Double dose of hepatitis B vaccine does not seem to provide any advantage when compared to standard dose in HIV-infected children.
Hepatitis B Vaccine