We searched EMBASE, PubMed, CENTRAL and clinicaltrials.gov. 
EMBASE
We searched EMBASE, PubMed, CENTRAL and clinicaltrials.gov. 
PubMed
We searched EMBASE, PubMed, CENTRAL and clinicaltrials.gov. 
CENTRAL
We searched EMBASE, PubMed, CENTRAL and clinicaltrials.gov. 
clinicaltrials.gov