Refractive index-based detection of gradient elution liquid chromatography using chip-integrated microring resonator arrays.Refractive index-based sensors offer attractive characteristics as nondestructive and universal detectors for liquid chromatographic separations, but a small dynamic range and sensitivity to minor thermal perturbations limit the utility of commercial RI detectors for many potential applications, especially those requiring the use of gradient elutions.  Microrings are easily configured into sensor arrays, and chip-integrated control microrings enable real-time corrections of thermal drift.  Thermal controls allow for analyses at any temperature and, in the absence of rigorous temperature control, obviates extended detector equilibration wait times. 
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