Growth inhibition and cell cycle effects were assessed for pathway inhibitors AZD6244 (MAPK) and rapamycin (PI3K/AKT) in human and canine melanoma cells.  Constitutive pathway activation and similar sensitivity to AZD6244 and rapamycin was observed in human and canine cells. 
AZD6244
Growth inhibition and cell cycle effects were assessed for pathway inhibitors AZD6244 (MAPK) and rapamycin (PI3K/AKT) in human and canine melanoma cells.  Constitutive pathway activation and similar sensitivity to AZD6244 and rapamycin was observed in human and canine cells. 
rapamycin