Macroscopic and microscopic spatially-resolved analysis of food contaminants and constituents using laser-ablation electrospray ionization mass spectrometry imaging.Laser-ablation electrospray ionization (LAESI) mass spectrometry imaging (MSI) does not require very flat surfaces, high-precision sample preparation, or the addition of matrix.  Because of these features, LAESI-MSI may be the method of choice for spatially-resolved food analysis.  In this work, LAESI time-of-flight MSI was investigated for macroscopic and microscopic imaging of pesticides, mycotoxins, and plant metabolites on rose leaves, orange and lemon fruit, ergot bodies, cherry tomatoes, and maize kernels.  However, according to three-dimensional LAESI-MSI the penetration depth of imazalil into the peel has significant local variation.  It is envisaged that LAESI-MSI will contribute to future research in food science, agriforensics, and plant metabolomics.
LAESI
Because of these features, LAESI-MSI may be the method of choice for spatially-resolved food analysis.  However, according to three-dimensional LAESI-MSI the penetration depth of imazalil into the peel has significant local variation.  It is envisaged that LAESI-MSI will contribute to future research in food science, agriforensics, and plant metabolomics.
LAESI-MSI
In this work, LAESI time-of-flight MSI was investigated for macroscopic and microscopic imaging of pesticides, mycotoxins, and plant metabolites on rose leaves, orange and lemon fruit, ergot bodies, cherry tomatoes, and maize kernels. 
LAESI time-of-flight MSI
For tomatoes, traveling-wave ion mobility (TWIM) was used to discriminate between different lycoperoside glycoalkaloid isomers; for maize quadrupole time-of-flight tandem mass spectrometry (MS-MS) was successfully used to elucidate the structure of a localized unknown. 
TWIM
For tomatoes, traveling-wave ion mobility (TWIM) was used to discriminate between different lycoperoside glycoalkaloid isomers; for maize quadrupole time-of-flight tandem mass spectrometry (MS-MS) was successfully used to elucidate the structure of a localized unknown. 
quadrupole time-of-flight tandem mass spectrometry (MS-MS)