SNARE-Reconstituted Liposomes as Controllable Zeptoliter Nanoreactors for Macromolecules.Liposomes are synthetic phospholipid vesicles containing an aqueous lumen confined by a lipid bilayer.  Furthermore, in order to deliver macromolecules larger than the threshold pore size into lipid-based nanoreactors, fusogenic soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins were employed to mediate membrane fusion between two liposomes to initiate reactions on demand without losing previously encapsulated macromolecules. 
SNARE
SNARE-Reconstituted Liposomes as Controllable Zeptoliter Nanoreactors for Macromolecules.Liposomes are synthetic phospholipid vesicles containing an aqueous lumen confined by a lipid bilayer.  However, a major limitation of using liposomes as nanocontainers is the impermeability of their lipid membranes.  To overcome this, scientists have tested the use of porous liposomes generated by membrane phase changes or by pore formation proteins.  In this study, the selective permeability of porous liposomes to molecules smaller than the threshold pore size is demonstrated for triggering internal reactions.  Furthermore, in order to deliver macromolecules larger than the threshold pore size into lipid-based nanoreactors, fusogenic soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins were employed to mediate membrane fusion between two liposomes to initiate reactions on demand without losing previously encapsulated macromolecules. 
liposomes
SNARE-Reconstituted Liposomes as Controllable Zeptoliter Nanoreactors for Macromolecules.Liposomes are synthetic phospholipid vesicles containing an aqueous lumen confined by a lipid bilayer. 
lipid bilayer
To overcome this, scientists have tested the use of porous liposomes generated by membrane phase changes or by pore formation proteins. 
membrane phase changes
To overcome this, scientists have tested the use of porous liposomes generated by membrane phase changes or by pore formation proteins. 
pore formation proteins
Furthermore, in order to deliver macromolecules larger than the threshold pore size into lipid-based nanoreactors, fusogenic soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) proteins were employed to mediate membrane fusion between two liposomes to initiate reactions on demand without losing previously encapsulated macromolecules. 
soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE)