Potential for measurement of the distribution of DNA folds in complex environments using Correlated X-ray Scattering.In vivo chromosomal behavior is dictated by the organization of genomic DNA at length scales ranging from nanometers to microns.  Here, we argue, based on simulations, that correlated X-ray scattering (CXS) has the potential for measuring the distribution of DNA folds in complex environments, on the scale of a few persistence lengths.
Correlated X-ray Scattering
Based on multiscale molecular simulations, we report on the possibility of measuring supercoiling in complex environments using angular correlations of scattered X-rays resulting from X-ray free electron laser (xFEL) experiments. 
X-ray free electron laser
Based on multiscale molecular simulations, we report on the possibility of measuring supercoiling in complex environments using angular correlations of scattered X-rays resulting from X-ray free electron laser (xFEL) experiments. 
xFEL