Neuroprotective effects of edaravone after intraventricular hemorrhage in rats.Intraventricular hemorrhage (IVH) is a severity factor and treatment target in intracerebral hemorrhage.  This study aimed to investigate whether systemic edaravone, a free-radical scavenger, could attenuate the brain injury after IVH in a rat model.  Immediate edaravone treatment after IVH can reduce IVH-induced brain edema and elevated lipid peroxidation.  Furthermore, repeated edaravone treatment (immediately, 24 h, and 48 h after IVH) improved the IVH-induced learning and memory damage.  These effects suggest that edaravone may be a potential therapeutic agent for IVH, especially those intracerebral hemorrhage patients with ventricular extension.
edaravone
Neuroprotective effects of edaravone after intraventricular hemorrhage in rats.Intraventricular hemorrhage (IVH) is a severity factor and treatment target in intracerebral hemorrhage.  This study aimed to investigate whether systemic edaravone, a free-radical scavenger, could attenuate the brain injury after IVH in a rat model.  Immediate edaravone treatment after IVH can reduce IVH-induced brain edema and elevated lipid peroxidation.  Furthermore, repeated edaravone treatment (immediately, 24 h, and 48 h after IVH) improved the IVH-induced learning and memory damage.  These effects suggest that edaravone may be a potential therapeutic agent for IVH, especially those intracerebral hemorrhage patients with ventricular extension.
edaravone
Neuroprotective effects of edaravone after intraventricular hemorrhage in rats.Intraventricular hemorrhage (IVH) is a severity factor and treatment target in intracerebral hemorrhage.  This study aimed to investigate whether systemic edaravone, a free-radical scavenger, could attenuate the brain injury after IVH in a rat model.  Immediate edaravone treatment after IVH can reduce IVH-induced brain edema and elevated lipid peroxidation.  Furthermore, repeated edaravone treatment (immediately, 24 h, and 48 h after IVH) improved the IVH-induced learning and memory damage.  These effects suggest that edaravone may be a potential therapeutic agent for IVH, especially those intracerebral hemorrhage patients with ventricular extension.
edaravone
Neuroprotective effects of edaravone after intraventricular hemorrhage in rats.Intraventricular hemorrhage (IVH) is a severity factor and treatment target in intracerebral hemorrhage.  This study aimed to investigate whether systemic edaravone, a free-radical scavenger, could attenuate the brain injury after IVH in a rat model.  Immediate edaravone treatment after IVH can reduce IVH-induced brain edema and elevated lipid peroxidation.  Furthermore, repeated edaravone treatment (immediately, 24 h, and 48 h after IVH) improved the IVH-induced learning and memory damage.  These effects suggest that edaravone may be a potential therapeutic agent for IVH, especially those intracerebral hemorrhage patients with ventricular extension.
edaravone