Light sheet-based fluorescence microscopy (LSFM) for the quantitative imaging of cells and tissues.In light sheet-based fluorescence microscopy (LSFM), only the focal plane is illuminated by a laser light sheet.  Therefore, LSFM (aka single/selective-plane illumination microscopy [SPIM] or digitally scanned light sheet microscopy [DSLM]) is the technique of choice for the three-dimensional imaging of live or fixed and of small or large three-dimensional specimens.  Recent developments address the penetration depth, the resolution and the recording speed of LSFM.  The impact of LSFM on research areas such as three-dimensional cell cultures, neurosciences, plant biology and developmental biology is increasing at a rapid pace.  The development of high-throughput LSFM is the next leap forward, allowing the application of LSFM in toxicology and drug discovery screening.
LSFM
Light sheet-based fluorescence microscopy (LSFM) for the quantitative imaging of cells and tissues.In light sheet-based fluorescence microscopy (LSFM), only the focal plane is illuminated by a laser light sheet.  Therefore, LSFM (aka single/selective-plane illumination microscopy [SPIM] or digitally scanned light sheet microscopy [DSLM]) is the technique of choice for the three-dimensional imaging of live or fixed and of small or large three-dimensional specimens.  Recent developments address the penetration depth, the resolution and the recording speed of LSFM.  The impact of LSFM on research areas such as three-dimensional cell cultures, neurosciences, plant biology and developmental biology is increasing at a rapid pace.  The development of high-throughput LSFM is the next leap forward, allowing the application of LSFM in toxicology and drug discovery screening.
LSFM
Light sheet-based fluorescence microscopy (LSFM) for the quantitative imaging of cells and tissues.In light sheet-based fluorescence microscopy (LSFM), only the focal plane is illuminated by a laser light sheet.  Therefore, LSFM (aka single/selective-plane illumination microscopy [SPIM] or digitally scanned light sheet microscopy [DSLM]) is the technique of choice for the three-dimensional imaging of live or fixed and of small or large three-dimensional specimens.  Recent developments address the penetration depth, the resolution and the recording speed of LSFM.  The impact of LSFM on research areas such as three-dimensional cell cultures, neurosciences, plant biology and developmental biology is increasing at a rapid pace.  The development of high-throughput LSFM is the next leap forward, allowing the application of LSFM in toxicology and drug discovery screening.
LSFM
Light sheet-based fluorescence microscopy (LSFM) for the quantitative imaging of cells and tissues.In light sheet-based fluorescence microscopy (LSFM), only the focal plane is illuminated by a laser light sheet.  Therefore, LSFM (aka single/selective-plane illumination microscopy [SPIM] or digitally scanned light sheet microscopy [DSLM]) is the technique of choice for the three-dimensional imaging of live or fixed and of small or large three-dimensional specimens.  Recent developments address the penetration depth, the resolution and the recording speed of LSFM.  The impact of LSFM on research areas such as three-dimensional cell cultures, neurosciences, plant biology and developmental biology is increasing at a rapid pace.  The development of high-throughput LSFM is the next leap forward, allowing the application of LSFM in toxicology and drug discovery screening.
LSFM
Light sheet-based fluorescence microscopy (LSFM) for the quantitative imaging of cells and tissues.In light sheet-based fluorescence microscopy (LSFM), only the focal plane is illuminated by a laser light sheet.  Therefore, LSFM (aka single/selective-plane illumination microscopy [SPIM] or digitally scanned light sheet microscopy [DSLM]) is the technique of choice for the three-dimensional imaging of live or fixed and of small or large three-dimensional specimens.  Recent developments address the penetration depth, the resolution and the recording speed of LSFM.  The impact of LSFM on research areas such as three-dimensional cell cultures, neurosciences, plant biology and developmental biology is increasing at a rapid pace.  The development of high-throughput LSFM is the next leap forward, allowing the application of LSFM in toxicology and drug discovery screening.
LSFM