Applications of MALDI-TOF mass spectrometry in clinical proteomics.The development of precision medicine requires advanced technologies to address the multifactorial disease stratification and to support personalized treatments.  From this perspective, Matrix Assisted Laser Desorption Ionization Time of Flight (MALDI-TOF) MS is a suitable platform for providing a high-throughput support to clinics.  Areas covered: This review aims to provide an updated overview of MALDI-TOF MS applications in clinical proteomics.  Expert commentary: Despite some analytical limitations, the latest technological advances together with the easiness of use, the low time and low cost consuming and the high throughput are making MALDI-TOF MS instruments very attractive for the clinical practice. 
MALDI-TOF
Applications of MALDI-TOF mass spectrometry in clinical proteomics.The development of precision medicine requires advanced technologies to address the multifactorial disease stratification and to support personalized treatments.  From this perspective, Matrix Assisted Laser Desorption Ionization Time of Flight (MALDI-TOF) MS is a suitable platform for providing a high-throughput support to clinics.  Areas covered: This review aims to provide an updated overview of MALDI-TOF MS applications in clinical proteomics.  Expert commentary: Despite some analytical limitations, the latest technological advances together with the easiness of use, the low time and low cost consuming and the high throughput are making MALDI-TOF MS instruments very attractive for the clinical practice. 
MALDI-TOF