Continuous Post-Market Sequential Safety Surveillance with Minimum Events to Signal.The CDC Vaccine Safety Datalink project has pioneered the use of near real-time post-market vaccine safety surveillance for the rapid detection of adverse events. 
CDC Vaccine Safety Datalink project
Continuous Post-Market Sequential Safety Surveillance with Minimum Events to Signal.The CDC Vaccine Safety Datalink project has pioneered the use of near real-time post-market vaccine safety surveillance for the rapid detection of adverse events. 
near real-time post-market vaccine safety surveillance
Doing weekly analyses, continuous sequential methods are used, allowing investigators to evaluate the data near-continuously while still maintaining the correct overall alpha level. 
sequential methods