Transcriptome analysis of adult Caenorhabditis elegans cells reveals tissue-specific gene and isoform expression.The biology and behavior of adults differ substantially from those of developing animals, and cell-specific information is critical for deciphering the biology of multicellular animals. 
Transcriptome analysis
Finally, we developed a machine learning-based prediction tool for 76 sub-tissue cell types, which we used to predict cellular expression differences in IIS/FOXO signaling, stage-specific TGF-β activity, and basal vs. memory-induced CREB transcription. 
machine learning-based prediction tool