Prescribed nanoparticle cluster architectures and low-dimensional arrays built using octahedral DNA origami frames.Three-dimensional mesoscale clusters that are formed from nanoparticles spatially arranged in pre-determined positions can be thought of as mesoscale analogues of molecules.  The frame is a DNA origami octahedron and can be used to fabricate clusters with various symmetries and particle compositions. 
DNA origami
Cryo-electron microscopy is used to uncover the structure of the DNA frame and to reveal that the nanoparticles are spatially coordinated in the prescribed manner. 
Cryo-electron microscopy