Of those tested, a new hybrid of a Local Hierarchical Classifier (LHC) and the Predictive Clustering Tree algorithm (LHC-PCT) had the best predictive accuracy results.  We conclude that the LHC-PCT algorithm ranks better across several tests (seven out of 12). 
LHC
Of those tested, a new hybrid of a Local Hierarchical Classifier (LHC) and the Predictive Clustering Tree algorithm (LHC-PCT) had the best predictive accuracy results.  We conclude that the LHC-PCT algorithm ranks better across several tests (seven out of 12).  In addition, we interpreted the models generated by the PCT algorithm to show how hierarchical classification algorithms can be used to extract biological insights out of the ageing-related datasets that we compiled.
PCT
(a) changing the base algorithm (we tested Naive Bayes and Support Vector Machines), and the impact of 
Naive Bayes
(a) changing the base algorithm (we tested Naive Bayes and Support Vector Machines), and the impact of 
Support Vector Machines
(b) using or not the Correlation based Feature Selection (CFS) algorithm in a pre-processing step. 
CFS