To compare cardiac left ventricular (LV) parameters in simultaneously acquired hybrid fluorine-18-fluorodeoxyglucose ([18F] FDG) positron emission tomography/magnetic resonance imaging (PET/MRI) in patients with residual tracer activity of upstream PET/CT.


 Twenty-nine patients (23 men, age 58±17 years) underwent cardiac PET/MRI either directly after a non-cardiac PET/CT with homogenous cardiac [18F] FDG uptake (n=20) or for viability assessment (n=9).  In simultaneously acquired cardiac PET/MRI data, LVEDV, LVESV and LVEF show good agreement.  However, the agreement seems to be limited if cardiac PET/MRI follows PET/CT and only the residual activity is used.


 • Cardiac volumes and function assessed by PET/MRI show good agreement. 
PET/MRI
Comparison of volumetric and functional parameters in simultaneous cardiac PET/MR: feasibility of volumetric assessment with residual activity from prior PET/CT.OBJECTIVE
 To compare cardiac left ventricular (LV) parameters in simultaneously acquired hybrid fluorine-18-fluorodeoxyglucose ([18F] FDG) positron emission tomography/magnetic resonance imaging (PET/MRI) in patients with residual tracer activity of upstream PET/CT.


 Twenty-nine patients (23 men, age 58±17 years) underwent cardiac PET/MRI either directly after a non-cardiac PET/CT with homogenous cardiac [18F] FDG uptake (n=20) or for viability assessment (n=9).  However, the agreement seems to be limited if cardiac PET/MRI follows PET/CT and only the residual activity is used.



PET/CT
To compare cardiac left ventricular (LV) parameters in simultaneously acquired hybrid fluorine-18-fluorodeoxyglucose ([18F] FDG) positron emission tomography/magnetic resonance imaging (PET/MRI) in patients with residual tracer activity of upstream PET/CT.


 Twenty-nine patients (23 men, age 58±17 years) underwent cardiac PET/MRI either directly after a non-cardiac PET/CT with homogenous cardiac [18F] FDG uptake (n=20) or for viability assessment (n=9).  In simultaneously acquired cardiac PET/MRI data, LVEDV, LVESV and LVEF show good agreement.  However, the agreement seems to be limited if cardiac PET/MRI follows PET/CT and only the residual activity is used.


 • [ 18 F] FDG PET-MRI is feasible with residual [ 18 F] FDG activity in patients with homogenous cardiac uptake.  • Cardiac volumes and function assessed by PET/MRI show good agreement.  • Cardiac PET and MRI data correlate better when acquired simultaneously than sequentially.  • PET and MRI should not assess LV parameters interchangeably.
MRI
Comparison of volumetric and functional parameters in simultaneous cardiac PET/MR: feasibility of volumetric assessment with residual activity from prior PET/CT.OBJECTIVE
 To compare cardiac left ventricular (LV) parameters in simultaneously acquired hybrid fluorine-18-fluorodeoxyglucose ([18F] FDG) positron emission tomography/magnetic resonance imaging (PET/MRI) in patients with residual tracer activity of upstream PET/CT.


 Twenty-nine patients (23 men, age 58±17 years) underwent cardiac PET/MRI either directly after a non-cardiac PET/CT with homogenous cardiac [18F] FDG uptake (n=20) or for viability assessment (n=9).  Gated cardiac [18F] FDG PET and cine MR sequences were acquired simultaneously and evaluated blinded to the cross-imaging results.  PET-IQ (0-3) was high (mean: 2.2±0.9) with significant influence on LVMM calculations only.


 In simultaneously acquired cardiac PET/MRI data, LVEDV, LVESV and LVEF show good agreement.  However, the agreement seems to be limited if cardiac PET/MRI follows PET/CT and only the residual activity is used.


 • [ 18 F] FDG PET-MRI is feasible with residual [ 18 F] FDG activity in patients with homogenous cardiac uptake.  • Cardiac volumes and function assessed by PET/MRI show good agreement.  • LVEDV and LVESV are underestimated; PET overestimates LVMM and LVEF.  • Cardiac PET and MRI data correlate better when acquired simultaneously than sequentially.  • PET and MRI should not assess LV parameters interchangeably.
PET