This study was aimed to compare the physical performances of cadmium-zinc-telluride (CZT) camera and conventional Anger camera.  Linear source studies were performed to evaluate extrinsic resolution of CZT camera (Discovery NM 530c, GE) and conventional single-photon emission computed tomography (SPECT) Anger camera (Symbia T2, Siemens).  Imaging performances were evaluated through count sensitivity, contrast-to-noise ratio, quantitative sharpness profile, wall thickness, perfusion uniformity (measured by standard deviation of perfusion percentage of 20 segments using quantitative perfusion SPECT (QPS) software, Cedars-Sinai), and visual imaging quality (using 20-segment sum defect scores (SDS) of QPS) for CZT camera, conventional SPECT without and with computed tomography transmission attenuation correction (AC).


 Myocardial walls measured on CZT images were thicker.  Images of CZT had lower SDS, while AC reduced the differences of SDS between CZT and CC.  Perfusion images from CZT had the better uniformity than SPECT without or with AC.  CZT camera has better physical performance and image quality with less artificial perfusion defects than conventional SPECT. 
GE
Linear source studies were performed to evaluate extrinsic resolution of CZT camera (Discovery NM 530c, GE) and conventional single-photon emission computed tomography (SPECT) Anger camera (Symbia T2, Siemens). 
Siemens
Imaging performances were evaluated through count sensitivity, contrast-to-noise ratio, quantitative sharpness profile, wall thickness, perfusion uniformity (measured by standard deviation of perfusion percentage of 20 segments using quantitative perfusion SPECT (QPS) software, Cedars-Sinai), and visual imaging quality (using 20-segment sum defect scores (SDS) of QPS) for CZT camera, conventional SPECT without and with computed tomography transmission attenuation correction (AC).



Cedars-Sinai