Although studying these processes in living cells has been challenging, the development of new Synthetic Biology techniques has opened unique opportunities to both manipulate and probe how these motors function in groups as they navigate the native cytoskeleton. 
Synthetic Biology
Here, we describe an approach to engineer mammalian cells for a new class of inducible cargo motility assays that utilize drug-dependent protein dimerization switches to regulate motor-cargo coupling and transport. 
cargo motility assays
Here, we describe an approach to engineer mammalian cells for a new class of inducible cargo motility assays that utilize drug-dependent protein dimerization switches to regulate motor-cargo coupling and transport. 
protein dimerization switches
Here, we describe an approach to engineer mammalian cells for a new class of inducible cargo motility assays that utilize drug-dependent protein dimerization switches to regulate motor-cargo coupling and transport. 
motor-cargo coupling and transport