Pyopneumothorax during bevacizumab-containing chemotherapy in a patient with metastatic breast cancer.Pyopneumothorax is a rare but troubling complication of bevacizumab.  We herein report a case of pyopneumothorax in a patient with metastatic breast cancer during bevacizumab treatment.  A 60-year-old female who was diagnosed with metastatic breast cancer (ER+ , PgR+ , HER2-, Ki67 <14 %, metastasized to lung, pleural, brain, subcutaneous tissue, and bone) was started on bevacizumab plus paclitaxel chemotherapy.  Our case indicates the successful management of a severe side effect of bevacizumab for a breast cancer patient.
bevacizumab
A 60-year-old female who was diagnosed with metastatic breast cancer (ER+ , PgR+ , HER2-, Ki67 <14 %, metastasized to lung, pleural, brain, subcutaneous tissue, and bone) was started on bevacizumab plus paclitaxel chemotherapy. 
paclitaxel