Furthermore, Ccdc181 seems to interact directly with microtubules and localizes to the microtubular manchette of elongating spermatids, resembling the previously reported localization of Hook1.  Furthermore, we showed that Ccdc181 is a putative interacting partner of the different catalytic subunits of Pp1, raising the hypothesis that Ccdc181 plays a role in mediating ciliary motility.
THERM