iPhone-based Pupillometry: A Novel Approach for Assessing the Pupillary Light Reflex.SIGNIFICANCE

iPhone-based Pupillometry
Pupil sizes were measured from 15 visually normal subjects (age, 19 to 65 years) using an IR camera system and the Sensitometer test.  Simultaneous recordings were obtained with the Sensitometer test and IR camera, and two measures were calculated: (1) dark-adapted steady-state pupil size and (2) minimum pupil size after the flash.  Statistically significant correlations between the IR and Sensitometer test measures were found for the PLR (r = 0.91, P < .001) and redilation size (r = 0.65, P = .03).  The PLR limit of agreement was 14%, indicating that 95% of subjects are expected to have IR and Sensitometer test measurements that differ by 14% or less.  There is excellent agreement between pupil responses recorded using the Sensitometer test and IR camera.  The Sensitometer test provides a highly promising approach for simple, portable, inexpensive pupillary measurements.
Sensitometer test
Pupil sizes were measured from 15 visually normal subjects (age, 19 to 65 years) using an IR camera system and the Sensitometer test. 
IR camera system