GWAS on family history of Alzheimer's disease.Alzheimer's disease (AD) is a public health priority for the 21st century. 
GWAS
We show that self-report of parental history of Alzheimer's dementia for case ascertainment in a genome-wide association study of 314,278 participants from UK Biobank (27,696 maternal cases, 14,338 paternal cases) is a valid proxy for an AD genetic study. 
UK Biobank