Smallpox is an infectious disease caused by the variola virus. Symptoms of smallpox include a fever, fatigue, and a distinctive rash. Smallpox is believed to have first appeared in human populations around 10,000 BCE. Throughout history, the disease has caused large-scale epidemics and mortality, particularly in the 18th and 19th centuries. By 1980, the disease had been effectively eradicated worldwide due to a successful global vaccination program.
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Smallpox是一种由天花病毒引起的高度传染性疾病，特点是发烧、疲劳和特殊皮疹等症状。它估计是在公元前10,000年首次出现于人类群体中。小痘病在历史上曾引起过大规模的流行病和死亡，特别是在18和19世纪。通过一次成功的全球疫苗接种计划，该疾病在1980年全球范围内被有效地根除了。