Answers.Body: <p>I would suggest looking into <a href="https://www.gencodegenes.org/human/" rel="nofollow noreferrer">GFF3 annotations</a> of the human genome.</p>
  <p>If what you want is <em>protein domain annotations</em>, you may be more interested in the <a href="https://ftp.uniprot.org/pub/databases/uniprot/current_release/knowledgebase/genome_annotation_tracks/" rel="nofollow noreferrer">UniProt database</a> which does seem to include <a href="https://ftp.uniprot.org/pub/databases/uniprot/current_release/knowledgebase/genome_annotation_tracks/UP000000589_10090_beds/" rel="nofollow noreferrer">genome annotation tracks</a> for different protein functional regions.</p>
  <p>I am unclear if uniprot directly has the gene names but this would be trivial to generate with a <code>bedtools intersect</code> operation.</p>
  
Answers.ContentLicense: CC BY-SA 4.0
Answers.CreationDate: 2024-02-01T21:06:40.457Z
Answers.LastActivityDate: 2024-02-01T21:06:40.457Z
Answers.UserDisplayName: Maximilian Press
Body: <p>I'm visualizing where mutations occur in a gene, and would like to add functional domains to the plots.</p>
  <p>I have some trouble locating sources to download data on functional domains.</p>
  <p>The dataset should contain:</p>
  <ul>
  <li>Functional domain name</li>
  <li>Start position in gene</li>
  <li>End position in gene</li>
  <li>Gene symbol name</li>
  </ul>
  <p>Any tips kindly appreciated!</p>
  
Comments.ContentLicense: CC BY-SA 4.0
Comments.CreationDate: 2024-01-08T15:31:27.507Z
Comments.Text: Please clarify your specific problem or provide additional details to highlight exactly what you need. As it's currently written, it's hard to tell exactly what you're asking.
Comments.UserDisplayName: Community
Tags: <genome><database><data-download><public-dataset><functional-annotation>
Title: Where can you download functional domain labels of the human genome?
ThreadText: # Where can you download functional domain labels of the human genome?
  
  (Asked by: username_0 on 2024-01-08)
  
  I'm visualizing where mutations occur in a gene, and would like to add functional domains to the plots.
  
  I have some trouble locating sources to download data on functional domains.
  
  The dataset should contain:
  
  * Functional domain name
  * Start position in gene
  * End position in gene
  * Gene symbol name
  
  Any tips kindly appreciated!
  
  **Tags:** genome, database, data-download, public-dataset, functional-annotation
  
  > **Comments:**
  > **username_1**: Please clarify your specific problem or provide additional details to highlight exactly what you need. As it's currently written, it's hard to tell exactly what you're asking.  
  
  ---
  
  ## 1 answers
  
  ### Answer by username_2 on 2024-02-01. Score: 0
  
  I would suggest looking into [GFF3 annotations](https://www.gencodegenes.org/human/) of the human genome.
  
  If what you want is *protein domain annotations*, you may be more interested in the [UniProt database](https://ftp.uniprot.org/pub/databases/uniprot/current_release/knowledgebase/genome_annotation_tracks/) which does seem to include [genome annotation tracks](https://ftp.uniprot.org/pub/databases/uniprot/current_release/knowledgebase/genome_annotation_tracks/UP000000589_10090_beds/) for different protein functional regions.
  
  I am unclear if uniprot directly has the gene names but this would be trivial to generate with a `bedtools intersect` operation.
  
  
  ---
  
  