Body: <p>In certain cases, traditional significance test may not be able to identify that effect of a treatment or a drug is significant. However,clinical significance test may suggest a significant effect. Does it mean that this test is a better way of interpreting  effect-size or correlation coefficient when we are facing imperfect measurements or data. Imperfect measurements could produce a wrong conclusion based on traditional statistical test?</p>
  
Comments.ContentLicense: CC BY-SA 4.0
Comments.CreationDate: 2024-02-06T00:58:23.143Z
Comments.Text: Your question is not clear. Can you give us an example where the significance test indicates a lack of significance (with good experimental design) but other evidence says otherwise?
Comments.UserDisplayName: Ram RS
Comments.ContentLicense: CC BY-SA 4.0
Comments.CreationDate: 2024-02-06T14:42:33.950Z
Comments.Text: I'm sorry but this is just too broad a question. If you [edit] and give a specific example we might be able to help if it is about bioinformatics, but as it stands, we cannot help you assess the results of a statistical test you haven't shown.
Comments.UserDisplayName: terdon
Comments.ContentLicense: CC BY-SA 4.0
Comments.CreationDate: 2024-02-08T22:28:59.043Z
Comments.Text: @RamRS please have a look. https://bioinformatics.stackexchange.com/questions/11043/difference-between-clinical-significance-and-statistical-significance
Comments.UserDisplayName: Subhash C. Davar
Comments.ContentLicense: CC BY-SA 4.0
Comments.CreationDate: 2024-02-09T15:31:51.437Z
Comments.Text: Thank you for the pointer, @SubhashC.Davar
Comments.UserDisplayName: Ram RS
Comments.ContentLicense: CC BY-SA 4.0
Comments.CreationDate: 2024-02-11T00:29:17.927Z
Comments.Text: @Ram RS Meta Analysis: please read my paper - An Improved Version of Hunter, Schmidt and Jackson Framework.
Comments.UserDisplayName: Subhash C. Davar
Tags: <r><biostatistics>
Title: In medical and public health care, should we make use of "clinical" signficance testing (non-parametric tests) or parametric tests of significance?"
ThreadText: # In medical and public health care, should we make use of "clinical" signficance testing (non-parametric tests) or parametric tests of significance?"
  
  (Asked by: username_0 on 2024-02-06)
  
  In certain cases, traditional significance test may not be able to identify that effect of a treatment or a drug is significant. However,clinical significance test may suggest a significant effect. Does it mean that this test is a better way of interpreting effect-size or correlation coefficient when we are facing imperfect measurements or data. Imperfect measurements could produce a wrong conclusion based on traditional statistical test?
  
  **Tags:** r, biostatistics
  
  > **Comments:**
  > **username_1**: Your question is not clear. Can you give us an example where the significance test indicates a lack of significance (with good experimental design) but other evidence says otherwise?  
  > **username_2**: I'm sorry but this is just too broad a question. If you [edit] and give a specific example we might be able to help if it is about bioinformatics, but as it stands, we cannot help you assess the results of a statistical test you haven't shown.  
  > **username_0**: @username_1 please have a look. https://bioinformatics.stackexchange.com/questions/11043/difference-between-clinical-significance-and-statistical-significance  
  > **username_1**: Thank you for the pointer, @SubhashC.username_0  
  > **username_0**: @username_1 Meta Analysis: please read my paper - An Improved Version of Hunter, Schmidt and Jackson Framework.  
  
  ---
  
  ## 0 answers
  
  