Answers.Body: <p>The easiest solution to the problem of mapping chemical compounds to protein IDs is to use the ChEMBL compound ID to UniProt <a href="ftp://ftp.ebi.ac.uk/pub/databases/chembl/ChEMBLdb/releases/chembl_24_1/chembl_uniprot_mapping.txt" rel="nofollow noreferrer">mapping</a>.</p>
  
  <p>Doing this with PubChem is not so straight forward in part because its downloadable data format is a hideous obfuscated and badly documented mess split over multiple compressed files which in turn contain multiple compressed files...... For a publicly funded project they should really do better.</p>
  
Answers.ContentLicense: CC BY-SA 4.0
Answers.CreationDate: 2018-07-24T14:40:15.183Z
Answers.LastActivityDate: 2018-07-24T14:40:15.183Z
Answers.UserDisplayName: Matt Bashton
Body: <p>I want to get all Pubchem Chemical compounds (CID) that interact with a given UniProt target. I have a list of UniProt targets and I need to study the relationship between these targets and chemical compounds.</p>
  
  <p>Thanks</p>
  
Tags: <uniprot><interactions>
Title: How to get all chemical compounds that interact with a given protein target?
ThreadText: # How to get all chemical compounds that interact with a given protein target?
  
  (Asked by: username_0 on 2018-07-23)
  
  I want to get all Pubchem Chemical compounds (CID) that interact with a given UniProt target. I have a list of UniProt targets and I need to study the relationship between these targets and chemical compounds.
  
  Thanks
  
  **Tags:** uniprot, interactions
  
  
  ---
  
  ## 1 answers
  
  ### Answer by username_1 on 2018-07-24. Score: 0 | Accepted answer
  
  The easiest solution to the problem of mapping chemical compounds to protein IDs is to use the ChEMBL compound ID to UniProt [mapping](ftp://ftp.ebi.ac.uk/pub/databases/chembl/ChEMBLdb/releases/chembl_24_1/chembl_uniprot_mapping.txt).
  
  Doing this with PubChem is not so straight forward in part because its downloadable data format is a hideous obfuscated and badly documented mess split over multiple compressed files which in turn contain multiple compressed files...... For a publicly funded project they should really do better.
  
  
  ---
  
  