Answers.Body: <p>Most likely yes, they are the same.</p>
  <p>However, &quot;NCBI37&quot; is an odd/unusual notation, because it doesn't indicate the species (human / mouse). Assuming it's a human genome (based on you comparing it to <em>hg</em>19 rather than <em>mm</em>19, or something else), then the correct name for the NCBI reference should be GRCh37.</p>
  <p>As it's a different name, we can only make guesses as to what the people who generated the VCF meant. You'll need to talk directly to them in order to be sure.</p>
  
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Answers.CreationDate: 2023-06-05T05:11:19.950Z
Answers.LastActivityDate: 2023-06-05T05:11:19.950Z
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Body: <p><em>This question was also asked on <a href="https://www.biostars.org/p/9565378/" rel="nofollow noreferrer">Biostars</a></em></p>
  <p>In other words, are NCBI37 and hg19 synonymous? I can't find much information for what NCBI37 is in a human (not mouse) genome.</p>
  <p>The VCF is from a lab sequencing human genomes, and they're no longer able to be reached out to. I can't provide a link to NCBI37 because I don't know what it is and I can't find much information on it.</p>
  <p>Relevant line from VCF:
  &quot;##reference=NCBI37&quot;</p>
  <p>Here is part of the VCF header:</p>
  <pre><code>##fileformat=VCFv4.2
  ##source=apt-format-result:2.10.2
  ##reference=NCBI37
  ##FORMAT=&lt;ID=GT,Number=1,Type=String,Description=&quot;Genotype&quot;&gt;
  ##contig=&lt;ID=1&gt;
  ##contig=&lt;ID=10&gt;
  ##contig=&lt;ID=11&gt;
  ##contig=&lt;ID=12&gt;
  ##contig=&lt;ID=19&gt; [omitted some chromosomes for brevity]
  ##contig=&lt;ID=2&gt;
  ##contig=&lt;ID=20&gt;
  ##contig=&lt;ID=MT&gt;
  ##contig=&lt;ID=X&gt;
  ##contig=&lt;ID=Y&gt;
  </code></pre>
  
Tags: <vcf><genome><reference-genome><hg19>
Title: Is a human genome file with reference as NCBI37 the same as hg19?
ThreadText: # Is a human genome file with reference as NCBI37 the same as hg19?
  
  (Asked by: username_0 on 2023-06-03)
  
  *This question was also asked on [Biostars](https://www.biostars.org/p/9565378/)*
  
  In other words, are NCBI37 and hg19 synonymous? I can't find much information for what NCBI37 is in a human (not mouse) genome.
  
  The VCF is from a lab sequencing human genomes, and they're no longer able to be reached out to. I can't provide a link to NCBI37 because I don't know what it is and I can't find much information on it.
  
  Relevant line from VCF:
  "##reference=NCBI37"
  
  Here is part of the VCF header:
  
  ```
  ##fileformat=VCFv4.2
  ##source=apt-format-result:2.10.2
  ##reference=NCBI37
  ##FORMAT=<ID=GT,Number=1,Type=String,Description="Genotype">
  ##contig=<ID=1>
  ##contig=<ID=10>
  ##contig=<ID=11>
  ##contig=<ID=12>
  ##contig=<ID=19> [omitted some chromosomes for brevity]
  ##contig=<ID=2>
  ##contig=<ID=20>
  ##contig=<ID=MT>
  ##contig=<ID=X>
  ##contig=<ID=Y>
  
  ```
  
  **Tags:** vcf, genome, reference-genome, hg19
  
  
  ---
  
  ## 1 answers
  
  ### Answer by username_1 on 2023-06-05. Score: 1 | Accepted answer
  
  Most likely yes, they are the same.
  
  However, "NCBI37" is an odd/unusual notation, because it doesn't indicate the species (human / mouse). Assuming it's a human genome (based on you comparing it to *hg*19 rather than *mm*19, or something else), then the correct name for the NCBI reference should be GRCh37.
  
  As it's a different name, we can only make guesses as to what the people who generated the VCF meant. You'll need to talk directly to them in order to be sure.
  
  
  ---
  
  