Body: <p>The paper <a href="https://www.nature.com/articles/s41467-018-03424-4#Sec19" rel="nofollow noreferrer">A comprehensive evaluation of module detection methods for gene expression data</a> says that: &quot;We first want to provide an overview of the characteristics and performance of current module detection methods to guide the biologist in their choice&quot;.</p>
  <p>My problem is that I have no gold standards for my gene dataset and I would like to know if I can use the paper results to choose a module detection method without the need of external validation measures and how can I justificate this generalization? I am not finding the justificative about how can I use this guiding.</p>
  
Comments.ContentLicense: CC BY-SA 4.0
Comments.CreationDate: 2022-04-25T02:15:00.763Z
Comments.Text: Please clarify your specific problem or provide additional details to highlight exactly what you need. As it's currently written, it's hard to tell exactly what you're asking.
Comments.UserDisplayName: Community
Comments.ContentLicense: CC BY-SA 4.0
Comments.CreationDate: 2022-04-26T04:26:44.330Z
Comments.Text: How does your dataset compare to the dataset in the paper? Without that information we can't answer the question (as noted also in your previously posted SE bio question).
Comments.UserDisplayName: Maximilian Press
Tags: <gene-expression><clustering>
Title: Can I use a benchmark to choose a clustering or module detection method for a gene dataset?
ThreadText: # Can I use a benchmark to choose a clustering or module detection method for a gene dataset?
  
  (Asked by: username_0 on 2022-04-24)
  
  The paper [A comprehensive evaluation of module detection methods for gene expression data](https://www.nature.com/articles/s41467-018-03424-4#Sec19) says that: "We first want to provide an overview of the characteristics and performance of current module detection methods to guide the biologist in their choice".
  
  My problem is that I have no gold standards for my gene dataset and I would like to know if I can use the paper results to choose a module detection method without the need of external validation measures and how can I justificate this generalization? I am not finding the justificative about how can I use this guiding.
  
  **Tags:** gene-expression, clustering
  
  > **Comments:**
  > **username_1**: Please clarify your specific problem or provide additional details to highlight exactly what you need. As it's currently written, it's hard to tell exactly what you're asking.  
  > **username_2**: How does your dataset compare to the dataset in the paper? Without that information we can't answer the question (as noted also in your previously posted SE bio question).  
  
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  ## 0 answers
  
  