Body: <p>I am trying to build a model for variant calling,but I am a bit confused how to pre-process the reads that has insertion and deletion and align them with reference?</p>
  <p>Should I add something to the location of insertion or deletion to reference or should I just delete from read?</p>
  
Comments.ContentLicense: CC BY-SA 4.0
Comments.CreationDate: 2022-05-23T15:34:57.477Z
Comments.Text: Can you provide some reference for why you think preprocessing is necessary?
Comments.UserDisplayName: Maximilian Press
Comments.ContentLicense: CC BY-SA 4.0
Comments.CreationDate: 2022-05-23T17:56:41.093Z
Comments.Text: Please clarify your specific problem or provide additional details to highlight exactly what you need. As it's currently written, it's hard to tell exactly what you're asking.
Comments.UserDisplayName: Community
Comments.ContentLicense: CC BY-SA 4.0
Comments.CreationDate: 2022-05-24T03:59:19.613Z
Comments.Text: Are you building a model specifically for deep variant, or trying to create your own model via a different algorithm?
Comments.UserDisplayName: gringer
Tags: <variant-calling>
Title: How deep variant and others preprocessed insertion and deletion for extracting candidate variant?
ThreadText: # How deep variant and others preprocessed insertion and deletion for extracting candidate variant?
  
  (Asked by: username_0 on 2022-05-23)
  
  I am trying to build a model for variant calling,but I am a bit confused how to pre-process the reads that has insertion and deletion and align them with reference?
  
  Should I add something to the location of insertion or deletion to reference or should I just delete from read?
  
  **Tags:** variant-calling
  
  > **Comments:**
  > **username_1**: Can you provide some reference for why you think preprocessing is necessary?  
  > **username_2**: Please clarify your specific problem or provide additional details to highlight exactly what you need. As it's currently written, it's hard to tell exactly what you're asking.  
  > **username_3**: Are you building a model specifically for deep variant, or trying to create your own model via a different algorithm?  
  
  ---
  
  ## 0 answers
  
  