Answers.Body: <p>Most <a href="https://www.ncbi.nlm.nih.gov/pubmed/?term=qtl+mapping+gwas" rel="nofollow noreferrer">papers</a> that I've looked at distinguish between looking for genotype/trait associations in mapping populations created by experimental crosses (QTL mapping) and looking for genotype/trait associations in populations of unrelated individuals (GWAS). No distinction is made between susceptibility to disease (often referred to as a case-control GWAS) and continuous traits (all of the big studies on genetic associations with <a href="https://www.nature.com/articles/ng.3097" rel="nofollow noreferrer">height</a> use the term GWAS, for example).</p>
  
  <p>Many of the papers in my first link use both methods, so you can take a look at them to get an idea of the advantages and limitations of each.</p>
  
Answers.ContentLicense: CC BY-SA 3.0
Answers.CreationDate: 2017-12-11T15:24:31.860Z
Answers.LastActivityDate: 2017-12-11T15:24:31.860Z
Answers.UserDisplayName: heathobrien
Body: <p>What are the differences between the two methods? </p>
  
  <p>What advantages does one have over the other, and what are their limitations relative to one another?</p>
  
Comments.ContentLicense: CC BY-SA 3.0
Comments.CreationDate: 2017-12-09T19:46:13.647Z
Comments.Text: This question is too broad, and is prone to subjective answers that aren't very helpful. Please try to narrow your question, preferably thinking about a specific task that you would like to carry out.
Comments.UserDisplayName: gringer
Tags: <genomics><gwas>
Title: What are the differences between GWAS and QTL mapping?
ThreadText: # What are the differences between GWAS and QTL mapping?
  
  (Asked by: username_0 on 2017-12-09)
  
  What are the differences between the two methods?
  
  What advantages does one have over the other, and what are their limitations relative to one another?
  
  **Tags:** genomics, gwas
  
  > **Comments:**
  > **username_1**: This question is too broad, and is prone to subjective answers that aren't very helpful. Please try to narrow your question, preferably thinking about a specific task that you would like to carry out.  
  
  ---
  
  ## 1 answers
  
  ### Answer by username_2 on 2017-12-11. Score: 2
  
  Most [papers](https://www.ncbi.nlm.nih.gov/pubmed/?term=qtl+mapping+gwas) that I've looked at distinguish between looking for genotype/trait associations in mapping populations created by experimental crosses (QTL mapping) and looking for genotype/trait associations in populations of unrelated individuals (GWAS). No distinction is made between susceptibility to disease (often referred to as a case-control GWAS) and continuous traits (all of the big studies on genetic associations with [height](https://www.nature.com/articles/ng.3097) use the term GWAS, for example).
  
  Many of the papers in my first link use both methods, so you can take a look at them to get an idea of the advantages and limitations of each.
  
  
  ---
  
  