Answers.Body: <p>Yes, they are base pair positions</p>
  
Answers.ContentLicense: CC BY-SA 4.0
Answers.CreationDate: 2021-11-23T14:24:56.377Z
Answers.LastActivityDate: 2021-11-23T14:24:56.377Z
Answers.UserDisplayName: Emily_Ensembl
Answers.Body: <p>HG19 refers to the <em>build</em> used as the reference genome. To extend on what @Emily_Ensembl said, base pair positions may change between different builds.</p>
  <p>Please look at the following link for a more detailed explanation: <a href="https://gatk.broadinstitute.org/hc/en-us/articles/360035890951-Human-genome-reference-builds-GRCh38-or-hg38-b37-hg19" rel="nofollow noreferrer">https://gatk.broadinstitute.org/hc/en-us/articles/360035890951-Human-genome-reference-builds-GRCh38-or-hg38-b37-hg19</a></p>
  
Answers.ContentLicense: CC BY-SA 4.0
Answers.CreationDate: 2021-11-23T16:27:39.170Z
Answers.LastActivityDate: 2021-11-23T16:27:39.170Z
Answers.UserDisplayName: h3ab74
Body: <p>I am looking at genomic data (HG19). I have many SNPs, their chromosomes and positions.
  I want to look at certain SNP (suppose its chromosome is 1 and position 77,226,919), and extract all SNPs in distance 1mb from that SNP.</p>
  <p>Are the HG19 position in terms of base-pairs? Meaning that I need to take all SNPs in position <span class="math-container">$77,226,919 \pm100,000$</span>? Or is it something else?</p>
  
Comments.ContentLicense: CC BY-SA 4.0
Comments.CreationDate: 2021-11-24T13:47:01.680Z
Comments.Text: A megabase is 1_000_000; not 100_000.
Comments.UserDisplayName: Wouter De Coster
Tags: <snp><gwas><hg19>
Title: HG19 Position meaning
ThreadText: # HG19 Position meaning
  
  (Asked by: username_0 on 2021-11-23)
  
  I am looking at genomic data (HG19). I have many SNPs, their chromosomes and positions.
  I want to look at certain SNP (suppose its chromosome is 1 and position 77,226,919), and extract all SNPs in distance 1mb from that SNP.
  
  Are the HG19 position in terms of base-pairs? Meaning that I need to take all SNPs in position $77,226,919 \pm100,000$? Or is it something else?
  
  **Tags:** snp, gwas, hg19
  
  > **Comments:**
  > **username_1**: A megabase is 1_000_000; not 100_000.  
  
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  ## 2 answers
  
  ### Answer by username_2 on 2021-11-23. Score: 2
  
  Yes, they are base pair positions
  
  
  ---
  
  ### Answer by username_3 on 2021-11-23. Score: 1
  
  HG19 refers to the *build* used as the reference genome. To extend on what @Emily\_Ensembl said, base pair positions may change between different builds.
  
  Please look at the following link for a more detailed explanation: <https://gatk.broadinstitute.org/hc/en-us/articles/360035890951-Human-genome-reference-builds-GRCh38-or-hg38-b37-hg19>
  
  
  ---
  
  