Answers.Body: <p>I don't know specifically about the UKBB RAP, however, Population Allele Count is the count of that specific allele genotyped in the population in question. In this case, it most likely refers to the population that your cohort is part of. The population allele frequency is the same thing but noted in terms of frequency, i.e. divided by 2 times the number of genotyped individuals in that population.</p>
  
Answers.ContentLicense: CC BY-SA 4.0
Answers.CreationDate: 2024-01-20T21:33:23.680Z
Answers.LastActivityDate: 2024-01-20T21:33:23.680Z
Answers.UserDisplayName: Yossi Farjoun
Body: <p>In UK biobank research environment</p>
  <p>In GENOMICS tab of UK BRAP, if I type <code>7:140476600-140480852</code> coordinate in search bar and the same time after filtering my cohort for this coordinate, in <code>ALLELE TABLE</code> I see columns like:</p>
  <pre><code>Cohort AF Cohort Allele Count Population AF Population Allele Count GnomAD AF
  </code></pre>
  <p><a href="https://i.sstatic.net/OH3UX.png" rel="nofollow noreferrer"><img src="https://i.sstatic.net/OH3UX.png" alt="enter image description here" /></a></p>
  <p>I Googled a lot but no clue where population allele count and frequency come from</p>
  <p>Does anyone have any experience with this?</p>
  
Tags: <allele-frequency><population-genetics><dnanexus>
Title: Population Allele Frequency
ThreadText: # Population Allele Frequency
  
  (Asked by: username_0 on 2024-01-17)
  
  In UK biobank research environment
  
  In GENOMICS tab of UK BRAP, if I type `7:140476600-140480852` coordinate in search bar and the same time after filtering my cohort for this coordinate, in `ALLELE TABLE` I see columns like:
  
  ```
  Cohort AF Cohort Allele Count Population AF Population Allele Count GnomAD AF
  
  ```
  
  [![enter image description here](https://i.sstatic.net/OH3UX.png)](https://i.sstatic.net/OH3UX.png)
  
  I Googled a lot but no clue where population allele count and frequency come from
  
  Does anyone have any experience with this?
  
  **Tags:** allele-frequency, population-genetics, dnanexus
  
  
  ---
  
  ## 1 answers
  
  ### Answer by username_1 on 2024-01-20. Score: 3 | Accepted answer
  
  I don't know specifically about the UKBB RAP, however, Population Allele Count is the count of that specific allele genotyped in the population in question. In this case, it most likely refers to the population that your cohort is part of. The population allele frequency is the same thing but noted in terms of frequency, i.e. divided by 2 times the number of genotyped individuals in that population.
  
  
  ---
  
  