Answers.Body: <p>In Ubuntu 22.04, install:</p>
  <pre><code>sudo apt install libcurl4-openssl-dev
  </code></pre>
  <p>Then reattempt:</p>
  <pre><code>if (!require(&quot;BiocManager&quot;, quietly = TRUE))
      install.packages(&quot;BiocManager&quot;)
  
  BiocManager::install(&quot;DSS&quot;)
  </code></pre>
  <p>Then upon completion:</p>
  <pre><code>library(DSS)
  Loading required package: Biobase
  Loading required package: BiocGenerics
  
  Attaching package: ‘BiocGenerics’                                                                                     
  
  The following objects are masked from ‘package:stats’:                                                                
                                                                                                                        
      IQR, mad, sd, var, xtabs                                                                                          
  ...                                                                                                                      
  </code></pre>
  
Answers.ContentLicense: CC BY-SA 4.0
Answers.CreationDate: 2023-11-06T08:21:17.740Z
Answers.LastActivityDate: 2023-11-06T08:21:17.740Z
Answers.UserDisplayName: 719016
Body: <p>I am attempting to install and use the Bioconductor package DSS on Ubuntu 22.04.</p>
  <p>Following the instructions here: <a href="https://bioconductor.org/packages/release/bioc/html/DSS.html" rel="nofollow noreferrer">https://bioconductor.org/packages/release/bioc/html/DSS.html</a></p>
  <p>I get to this error:</p>
  <pre><code>hfile_libcurl.c:45:10: fatal error: curl/curl.h: No such file or directory     
     45 | #include &lt;curl/curl.h&gt;                                                                                        
        |          ^~~~~~~~~~~~~                                                                                        
  compilation terminated.                                                                                               
  make[1]: *** [Makefile.Rhtslib:128: hfile_libcurl.o] Error 1                 
  make[1]: Leaving directory '/tmp/RtmpNry6uq/R.INSTALL10673560786c68/Rhtslib/src/htslib-1.7'
  make: *** [Makevars.common:24: htslib] Error 2  
  </code></pre>
  
Tags: <differential-methylation>
Title: installing and using differential methylation DSS software
ThreadText: # installing and using differential methylation DSS software
  
  (Asked by: username_0 on 2023-11-06)
  
  I am attempting to install and use the Bioconductor package DSS on Ubuntu 22.04.
  
  Following the instructions here: <https://bioconductor.org/packages/release/bioc/html/DSS.html>
  
  I get to this error:
  
  ```
  hfile_libcurl.c:45:10: fatal error: curl/curl.h: No such file or directory     
     45 | #include <curl/curl.h>                                                                                        
        |          ^~~~~~~~~~~~~                                                                                        
  compilation terminated.                                                                                               
  make[1]: *** [Makefile.Rhtslib:128: hfile_libcurl.o] Error 1                 
  make[1]: Leaving directory '/tmp/RtmpNry6uq/R.INSTALL10673560786c68/Rhtslib/src/htslib-1.7'
  make: *** [Makevars.common:24: htslib] Error 2  
  
  ```
  
  **Tags:** differential-methylation
  
  
  ---
  
  ## 1 answers
  
  ### Answer by username_0 on 2023-11-06. Score: 1
  
  In Ubuntu 22.04, install:
  
  ```
  sudo apt install libcurl4-openssl-dev
  
  ```
  
  Then reattempt:
  
  ```
  if (!require("BiocManager", quietly = TRUE))
      install.packages("BiocManager")
  
  BiocManager::install("DSS")
  
  ```
  
  Then upon completion:
  
  ```
  library(DSS)
  Loading required package: Biobase
  Loading required package: BiocGenerics
  
  Attaching package: ‘BiocGenerics’                                                                                     
  
  The following objects are masked from ‘package:stats’:                                                                
                                                                                                                        
      IQR, mad, sd, var, xtabs                                                                                          
  ...                                                                                                                      
  
  ```
  
  
  ---
  
  