In enzymology, a progesterone monooxygenase (EC 1.14.99.4) is an enzyme that catalyzes the chemical reaction
progesterone + AH2 + O2 formula_1 testosterone acetate + A + H2O
The 3 substrates of this enzyme are progesterone, AH2, and O2, whereas its 3 products are testosterone acetate, A, and H2O.
This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O miscellaneous. The systematic name of this enzyme class is progesterone,hydrogen-donor:oxygen oxidoreductase (hydroxylating). This enzyme is also called progesterone hydroxylase.
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