Protein-coding gene in the species Homo sapiens
TNNI3 interacting kinase is a protein that in humans is encoded by the TNNI3K gene.
Function.
This gene encodes a protein that belongs to the MAP kinase kinase kinase (MAPKKK) family of protein kinases. The protein contains ankyrin repeat, protein kinase and serine-rich domains and is thought to play a role in cardiac physiology.
Clinical significance.
Mutations in TNNI3K are associated to cardiomyopathies.
References.
 ;templatestyles src="Reflist/styles.css" / ;
Further reading.
 ;templatestyles src="Refbegin/styles.css" / ;
"This article incorporates text from the United States National Library of Medicine, which is in the public domain."