Protein-coding gene in the species Homo sapiens
Autophagy related 9B is a protein that in humans is encoded by the ATG9B gene.
Function.
This gene functions in the regulation of autophagy, a lysosomal degradation pathway. This gene also functions as an antisense transcript in the post-transcriptional regulation of the endothelial nitric oxide synthase 3 gene, which has 3' overlap with this gene on the opposite strand. Mutations in this gene and disruption of the autophagy process have been associated with multiple cancers. Alternative splicing results in multiple transcript variants.
References.
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Further reading.
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"This article incorporates text from the United States National Library of Medicine, which is in the public domain."