 
The 2021 Louisiana's 2nd congressional district special election was held on March 20, 2021, with a runoff being held on April 24, 2021.
On November 17, 2020, incumbent Democratic representative Cedric Richmond announced that he would resign from the United States House of Representatives to serve as the director of the Office of Public Liaison and as a Senior Advisor to Joe Biden. He did so on January 15, 2021, and took his new job when Biden assumed office on January 20, 2021. When congressional seats in Louisiana become vacant, the governor has the ability to call a special election at any time. The special election to fill Louisiana's 2nd congressional district took place on March 20, and a runoff was held on April 24. Troy Carter won the runoff election on April 24, 2021, against fellow Democrat Karen Peterson.
Primary candidates.
Democratic Party.
Of the Democratic candidates, Troy Carter, a state senator, Karen Carter Peterson, a state senator and former chair of the Louisiana Democratic Party, and Gary Chambers, an activist, were considered the frontrunners. Of these candidates, Carter was considered to be moderate, while Peterson and Chambers were considered to be progressives. In the jungle primary, Carter and Peterson took first and second place with 36% and 23% of the vote, while Chambers took third place with 21%. Chambers' result was considered an overperformance, as he significantly outdid his polling numbers. On March 29, Chambers endorsed Peterson.
Endorsements.
 ;templatestyles src="Endorsements box/styles.css"/ ;Claston Bernard (R)
U.S. Representatives
State legislators
Individuals
Organizations
 ;templatestyles src="Endorsements box/styles.css"/ ;Troy Carter (D)
Executive Branch officials
U.S. Representatives
State legislators
Local officials
Newspapers
Organizations
 ;templatestyles src="Endorsements box/styles.css"/ ;Gary Chambers (D)
Individuals
 ;templatestyles src="Endorsements box/styles.css"/ ;Karen Carter Peterson (D)
U.S. Representatives
State legislators
Local officials
Organizations
Jungle primary.
Polling.
Graphical summary.
 ;templatestyles src="Template:Hidden begin/styles.css"/ ;Hypothetical polling
Notes.
Additional candidates and polling key
Partisan clients
References.
 ;templatestyles src="Reflist/styles.css" / ;
External links.
Official campaign websites