 
The 1946 Pennsylvania gubernatorial election was held on November 5, 1946. Republican Party nominee James H. Duff defeated Democratic Party nominee John S. Rice to become Governor of Pennsylvania. As of 2025, this was the last time Philadelphia County voted for the Republican candidate.
Democratic primary.
Candidates.
The endorsed candidates for Democratic Party won by a large margin, with Rice winning by a three-quarters of the vote over Mahanoy City businessman Henry Morris.
Results.
! scope="col" colspan="2" style="width: 15em" |Party
! scope="col" style="width: 17em" |Candidate
! scope="col" style="width: 5em" |Votes
! scope="col" style="width: 3.5em" |%
! colspan="3" style="text-align:right;" | Total votes
Republican primary.
Candidates.
The endorsed candidate for the Republican Party won by a large margin, with Duff earning over three-quarters of the vote against outgoing Secretary of Highways John Shroyer of Shamokin.
Results.
! scope="col" colspan="2" style="width: 15em" |Party
! scope="col" style="width: 17em" |Candidate
! scope="col" style="width: 5em" |Votes
! scope="col" style="width: 3.5em" |%
! colspan="3" style="text-align:right;" | Total votes
General election.
Campaign.
A close confidant of popular outgoing Governor Ed Martin, who was running for a US Senate seat, Duff was the clear favorite throughout the campaign. Duff ran as a moderate progressive but also as a hardline anti-communist. He promised to address the key topic of labor strife by limiting strikes and cracking down on union criminal activity while concurrently increasing the minimum wage. Duff also vowed to spur innovation amongst the state's fragmented local governments.
Results.
! scope="col" colspan="2" style="width: 15em" |Party
! scope="col" style="width: 17em" |Candidate
! scope="col" style="width: 5em" |Votes
! scope="col" style="width: 3.5em" |%
! colspan="3" style="text-align:right;" | Total votes
References.
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