Chemical compound
 ;templatestyles src="Infobox drug/styles.css"/ ;
 | vaccine = Vaccine description
 | combo = Combination of
 | mab = Monoclonal antibody
 | #default =
 |inactivated |killed = Inactivated
 |attenuated = Attenuated
 |live = Live bacteria
 |viral = Viral vector
 |toxoid = Toxoid
 |subunit = Subunit
 |protein |protein subunit = Protein subunit
 |peptide |peptide subunit = Peptide subunit
 |polysaccharide = Polysaccharide
 |vlp = Virus-like particles
 |conjugate = Conjugate
 |recombinant = Recombinant vector
 |dna = DNA
 |rna = RNA
 |mrna = mRNA
 |heterologous = Heterologous
 | mab = Whole antibody
 | fab = Fab fragment
 | f(ab')2 = F(ab')2 fragment
 | fab' = Fab' fragment
 | scfv = Single-chain variable fragment
 | discfv = Di-single-chain variable fragment
 | sdab = Single domain antibody
 | 3funct = Trifunctional antibody
 | clfab = Chemically linked Fab
 | bite = Bi-specific T-cell engager
 |INN_EMA=
 | _EMA_use_INN={{ParameterUseFirst
 |1=
 |3=
 |licence_US=
 |DailyMedID=
 |licence_CA=
 |legal_AU=
 |legal_BR=
 |legal_CA=
 |legal_DE=
 |legal_NZ=
 |legal_UK=
 |legal_EU=
 |legal_UN=
 |legal_AU_comment=
 |legal_BR_comment=
 |legal_CA_comment=
 |legal_DE_comment=
 |legal_NZ_comment=
 |legal_UK_comment=
 |legal_US_comment=
 |legal_EU_comment=
 |legal_UN_comment=
 |legal_status=
 | label71 = Bioavailability
 | data71 = 
 | label72 = Protein binding
 | data72 = 
 | label73 = Metabolism
 | data73 = {{#if: ||{{#if:
 | label74 = Metabolites
 | data74 = 
 | label75 = Onset of action
 | data75 = 
 | data76 = 
 | label77 = Duration of action
 | data77 = 
 | label78 = Excretion
 | data78 = 
 | data81 = {{#switch:{{lc:}} |mab|combo|vaccine= |#default={{#if:2-[2,3-dihydro-1"H"-inden-2-yl-[(2"S")-2-[[(2"S")-1-ethoxy-1-oxo-4-phenylbutan-2-yl]amino]propanoyl]amino]acetic acid
 | label102 = [[Chemical formula|Formula]]
 | data102 = {{Infobox drug/chemical formula
 | label103 = [[Molar mass]]
 | data103 = {{Chem molar mass
 | label104 = 3D model ([[JSmol]])
 | data104 = {{#ifeq:|none||{{unbulleted list
 | label106 = [[Chirality (chemistry)|Chirality]]
 | data106 = 
 | label107 = [[Specific rotation]]
 | data107 = 
 | label111 = [[Density]]
 | data111 = {{#if: |  g/cm3}} 
 | label112= [[Melting point]]
 | data112 = {{#if:|{{convert| {{#if:|to |}}|C|F}} }} 
 | label113 = [[Boiling point]]
 | data113 = {{#if:|{{convert| {{#if:|to |}}|C|F}} }} 
 | label114 = [[Aqueous solution|Solubility in water]]
 | data118 = [Email] | {{Collapsible list
 |liststyle=word-break:break-all;
 |title = [[Simplified molecular-input line-entry system|SMILES]]
 | data119 = {{#if:1S/C26H32N2O5/c1-3-33-26(32)23(14-13-19-9-5-4-6-10-19)27-18(2)25(31)28(17-24(29)30)22-15-20-11-7-8-12-21(20)16-22/h4-12,18,22-23,27H,3,13-17H2,1-2H3,(H,29,30)/t18-,23-/m0/s1|
 {{Collapsible list
 |liststyle=word-break:break-all;
 |title=[[International Chemical Identifier|InChI]]
 |1={{#if:1S/C26H32N2O5/c1-3-33-26(32)23(14-13-19-9-5-4-6-10-19)27-18(2)25(31)28(17-24(29)30)22-15-20-11-7-8-12-21(20)16-22/h4-12,18,22-23,27H,3,13-17H2,1-2H3,(H,29,30)/t18-,23-/m0/s1
 |2={{#if:WOUOLAUOZXOLJQ-MBSDFSHPSA-N
 |Key:WOUOLAUOZXOLJQ-MBSDFSHPSA-N
 |3={{#if:
 |{{#if:1S/C26H32N2O5/c1-3-33-26(32)23(14-13-19-9-5-4-6-10-19)27-18(2)25(31)28(17-24(29)30)22-15-20-11-7-8-12-21(20)16-22/h4-12,18,22-23,27H,3,13-17H2,1-2H3,(H,29,30)/t18-,23-/m0/s1WOUOLAUOZXOLJQ-MBSDFSHPSA-N
 |4={{#if:
}}{{#invoke:TemplatePar
source_tissues= target_tissues= receptors= agonists= antagonists= precursor= biosynthesis=
gt_target_gene= gt_vector= gt_nucleic_acid_type= gt_editing_method= gt_delivery_method=
sec_combustion=
Ac=Ag=Al=Am=Ar=As=At=Au=B=Ba=Be=Bh=Bi=Bk=Br=C=Ca=Cd=Ce=Cf=Cl=Cm=Cn=Co=Cr=Cs=Cu=
D=Db=Ds=Dy=Er=Es=Eu=F=Fe=Fl=Fm=Fr=Ga=Gd=Ge=H=He=Hf=Hg=Ho=Hs=I=In=Ir=K=Kr=La=Li=Lr=Lu=Lv=
Mc=Md=Mg=Mn=Mo=Mt=N=Na=Nb=Nd=Ne=Nh=Ni=No=Np=O=Og=Os=P=Pa=Pb=Pd=Pm=Po=Pr=Pt=Pu=Ra=Rb=Re=Rf=Rg=Rh=Rn=Ru=S=Sb=Sc=Se=Sg=Si=Sm=Sn=Sr=Ta=Tb=Tc=Te=Th=Ti=Tl=Tm=Ts=U=V=W=Xe=Y=Yb=Zn=Zr=
index_label= index2_label= index_comment= index2_comment=
CAS_number2= CAS_supplemental2= ATC_prefix2= ATC_suffix2= ATC_supplemental2= PubChem2= PubChemSubstance2= IUPHAR_ligand2= DrugBank2= ChemSpiderID2= UNII2= KEGG2= ChEBI2= ChEMBL2= PDB_ligand2= NIAID_ChemDB2= SMILES2= smiles2= StdInChI2= StdInChIKey2=
CAS_number2_Ref= ChEBI2_Ref= ChEMBL2_Ref= ChemSpiderID2_Ref= DrugBank2_Ref= KEGG2_Ref= StdInChI2_Ref= StdInChIKey2_Ref= UNII2_Ref= DTXSID2=
QID= QID2=PLLR= pregnancy_US= pregnancy_US_comment=
C09
Delapril ([[International Nonproprietary Name|INN]], also known as alindapril) is an [[ACE inhibitor]] used as an [[antihypertensive]] drug in some European and Asian countries but not in America. It is taken orally, available in 15 mg and 30 mg tablets.
Mechanism.
Delapril is a prodrug; it is converted into two active metabolites, 5-hydroxy delapril diacid and delapril diacid. These metabolites bind completely to and inhibit [[angiotensin-converting enzyme]] (ACE), hence blocking angiotensin I to angiotensin II conversion. The resulting vasodilation prevents the vasoconstrictive effects of angiotensin II. Angiotensin II-induced aldosterone secretion by the adrenal cortex is also decreased by Delapril, leading to increases in excretion of sodium and therefore increases water outflow.
References.
 ;templatestyles src="Reflist/styles.css" / ;
[[Category:2-Aminoindanes]]
[[Category:ACE inhibitors]]
[[Category:Acetic acids]]
[[Category:Enantiopure drugs]]
[[Category:Ethyl esters]]
[[Category:Prodrugs]]
[[Category:Propionamides]]
[[Category:Drugs developed by Takeda Pharmaceutical Company]]