"Mistrustin' Blues" is a song written by Johnny Otis. It was sung by Little Esther and Mel Walker, accompanied by The Johnny Otis Orchestra, and released on the Savoy label (catalog no. 735-A). The record was the second collaboration between Johnny Otis and Little Esther. "Mistrustin Blues" was their second number one record on the R&amp;B chart, which it topped for four weeks. It was ranked No. 10 on "Billboard" magazine's year-end list of R&amp;B records for 1950 based on sales (No. 15 based on juke box plays).
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