Protein-coding gene in the species Homo sapiens
Inositol polyphosphate-4-phosphatase, type II, 105kDa is a protein that in humans is encoded by the INPP4B gene.
INPP4B encodes the inositol polyphosphate 4-phosphatase type II, a dual specificity phosphatase. INPP4B is involved in phosphatidylinositol signaling pathways. This enzyme removes the phosphate group at position 4 of the inositol ring from inositol 3,4-bisphosphate and phosphate groups from phosphotyrosines. There is limited data to suggest that the human type II enzyme is subject to alternative splicing, as has been established for the type I enzyme.
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"This article incorporates text from the United States National Library of Medicine, which is in the public domain."