Membrane-spanning 4A genes are members of the CD20-like family. The MS4A genes are usually organized in a single genomic clusters in mammals, suggestive of gene duplication events. MS4A genes encode a class of four-transmembrane spanning proteins. MS4A genes have been described to act as a specific kind of olfactory receptor in the necklace olfactory sensory neurons in mice (Mus musculus).
In human ("Homo sapiens") the members of this family include:
References.
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