British biochemist
Frances Mary Platt (née Judson) is a biologist whose research has focused on biochemistry and pharmacology Her research investigates rare genetic disorders known as lysosomal storage diseases, which are progressive conditions that typically lead to neurodegeneration. She is a Professor at the University of Oxford and currently Head of the Department of Pharmacology. She was elected Fellow of the Academy of Medical Sciences in 2011, and Fellow of the Royal Society in 2021.
Early life and education.
Platt was born in Shipley, West Yorkshire. Since childhood she has had a strong interest in science and the natural world and took a degree in zoology at Imperial College London. Platt went to the University of Bath for a PhD studying insect endocrinology.
Research and career.
In 1986, Platt moved to the US as a postdoctoral researcher at Washington University School of Medicine, where she investigated cell surface molecules on B cells in germinal centres.In 1987 the head of the research team, Joseph Davie MD PhD moved to the pharmaceutical arm of Monsanto (GD Searle), where Platt learnt about industrial research and started working on antiviral drugs.
In 1989 she moved back to the UK as a Senior Research Fellow in the Glycobiology Institute, Department of Biochemistry in the University of Oxford. In 1996 Platt was the recipient of a five-year Lister Institute Senior Research Fellowship. In 2008 she became Professor of Biochemistry and Pharmacology in the Department of Pharmacology and Head of the department in 2020. 
Platt researches genetic disorders known as lysosomal storage diseases. The lysosome is an organelle within cells that is involved with breaking down large molecules. When it goes wrong, molecules accumulate in the lysosome resulting in lysosomal storage diseases.
Her expertise relates to glycosphingolipids (GSL) and glycosphingolipid lysosomal storage diseases. Together with her colleagues Terry Butters and Raymond Dwek, Platt pioneered a novel approach to treat these genetic disorders that has led to the development of an approved drug (miglustat) for type 1 Gaucher disease and Niemann-Pick disease type C disease. She is an academic co-founder of the company IntraBio and her translational work has continued as the companies lead drug Aqneursa was FDA approved in September 2024 for the treatment of Niemann-Pick disease type C. Currently her research focuses on the pathophysiology and treatment of lysosomal storage diseases and their links to Parkinson's disease.