Lake Waccamaw Depot is a historic train station located at Lake Waccamaw, Columbus County, North Carolina It was built about 1900 by the Atlantic Coast Line Railroad, and is a one-story, Stick Style frame building with board-and-batten siding. It features shaped eave brackets, gable braces, and a long low slate covered gabled roof. The building was moved to its present location in 1974. Also on the property is the contributing a rectangular board-and-batten covered Section House.
It was listed on the National Register of Historic Places in 1983.
The depot is now operated as the Lake Waccamaw Depot Museum, with displays of local history and natural history.
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