Antimicrobial peptide immune gene of fruit flies
Daisho ("Dso") is an antimicrobial peptide gene family of the fruit fly "Drosophila melanogaster". Two Daisho genes (Dso1, Dso2) are encoded in tandem in the fruit fly genome, one shorter than the other. This pair of genes with different length was named "Daisho" in reference to Daisho Japanese swords, which come in pairs with one shorter than the other.
The Daisho genes are regulated by "Drosophila" Toll-like receptor signalling. Daisho peptides protect flies against filamentous fungi, particularly "Fusarium" and also "Aspergillus". Daisho peptides are part of the "Drosophila" antifungal effector peptide response, which includes the gene families Bomanin, Drosomycin, Metchnikowin, and Baramicin.
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