Tubulinyl-Tyr carboxypeptidase (EC 3.4.17.17, "carboxypeptidase-tubulin", "soluble carboxypeptidase", "tubulin-tyrosine carboxypeptidase", "tubulin carboxypeptidase", "tubulinyltyrosine carboxypeptidase", "tyrosinotubulin carboxypeptidase", "tyrosyltubulin carboxypeptidase", "TTCPase", "brain I carboxypeptidase") is an enzyme. This enzyme catalyses the following chemical reaction
 Cleavage of the -Glu--Tyr bond to release the C-terminal tyrosine residue from the native tyrosinated tubulin. Inactive on Z-Glu-Tyr
This enzyme is active at neutral pH.
This activity has been linked to proteins such as AGTPBP1 in human.
References.
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