Protein-coding gene in the species Homo sapiens
Activating transcription factor 7-interacting protein 1 is a protein that in humans is encoded by the "ATF7IP" gene.
Interactions.
ATF7IP has been shown to interact with MBD1. In mice with T cell-specific deletion of Atf7ip, the protein has been shown to play a role in regulating T helper 17 cell (Th17) differentiation due to increased IL-2 production upon stimulation of the T cell receptor (TCR). This TCR stimulation occurs through deposition of H3K9me3, a repressive histone mark.
References.
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Further reading.
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