Protein-coding gene in the species Homo sapiens
Apolipoprotein A-I-binding protein also known as APOA1BP is a protein that in humans is encoded by the "APOA1BP" gene. Progressive encephalopathy with brain edema and/or leukoencephalopathy-1 (PEBEL-1), a rare, lethal, neurometabolic disorder, is caused by mutation in "NAXE" gene ("APOA1BP" being its former name).
Structure.
"APOA1BP" gene is located on chromosome 1, with its specific location being 1q22. The gene contains 6 exons, 5 introns, and spans 2.5 kb. Expression is ubiquitous across all human tissues, with highest observed in kidney, heart, liver, testis, thyroid gland, adrenal gland. APOA1BP contains Yje_FN domain. 
Function.
APOA1BP binds to APOA1, APOA2, and high-density lipoprotein (HDL). In addition, APOA1BP appears to play a role in sperm capacitation. It has been demonstrated that APOA1BP is involved in angiogenesis regulation, by accelerating cholesterol efflux from endothelial cells to HDL. It is known that zebrafish "APOA1BP" ortholog "Aibp" is involved in angiogenesis regulation. The protein was also shown to be involved in atherosclerosis protection. 
References.
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