Chepo is a town and corregimiento in Chepo District, Panamá Province, Panama with a population of 20,420 as of 2010. It is the seat of Chepo District. Its population as of 1990 was 8,971; its population as of 2000 was 12,734. It is located five kilometers south of the Inter-American Highway. It is a sprawling town that is nearly a suburb of Panama City. It contains a gas station, hospital, ATM, and a variety of stores. The Panamanian Minister of Public Work announced a new highway expansion connecting Pacora to Chepo 
The Darién Gap formerly began at Chepo, where the Panamerican Highway ended; after jungle, it begins again at Turbo, Colombia. Chepo was formerly a transshipment point and base for adventure travel outfitters. Since completion of the paved highway to Yaviza about 2008, most of this economic activity has moved to Metetí or Yaviza.
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