Endothiapepsin (EC 3.4.23.22, "Endothia aspartic proteinase", "Endothia acid proteinase", "Endothia parasitica acid proteinase", "Endothia parasitica aspartic proteinase") is an enzyme. This enzyme catalyses the following chemical reaction
 Hydrolysis of proteins with specificity similar to that of pepsin A; prefers hydrophobic residues at P1 and P1', but does not cleave Ala14-Leu in the B chain of insulin or Z-Glu-Tyr. Clots milk
This enzyme is isolated from the ascomycete "Endothia parasitica".
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