Protein and coding gene in humans
Galactoside 2-alpha-L-fucosyltransferase 2 is an enzyme that in humans is encoded by the "FUT2" gene. It affects the secretor status of ABO antigens.
Approximately 20% of Caucasians are non-secretors due to the G428A (rs601338) and C571T (rs492602?) nonsense mutations in FUT2 and therefore have strong although not absolute protection from the norovirus GII.4.
References.
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Further reading.
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