Protein-coding gene in the species Homo sapiens
Gamma-interferon-inducible lysosomal thiol reductase is an enzyme that, in humans, is encoded by the "IFI30" gene.
The protein encoded by this gene is a lysosomal thiol reductase that at low pH can reduce protein disulfide bonds. The enzyme is expressed constitutively in antigen-presenting cells and induced by gamma-interferon in other cell types. This enzyme has an important role in MHC class II-restricted antigen processing.
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Further reading.
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