Protein-coding gene in the species Homo sapiens
Coatomer subunit epsilon is a protein that in humans is encoded by the "COPE" gene.
Function.
The product of this gene is an epsilon subunit of coatomer protein complex. Coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles. It is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. Coatomer complex consists of at least the alpha, beta, beta', gamma, delta, epsilon and zeta subunits. Alternatively spliced transcript variants encoding different isoforms have been identified.
Interactions.
COPE (gene) has been shown to interact with COPA.
References.
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Further reading.
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