William Graham, 2nd Duke of Montrose (27 August 1712 – 23 September 1790) was a British nobleman. He the son of James Graham, 1st Duke of Montrose and his wife, Lady Christian Carnegie, daughter of David Carnegie, 3rd Earl of Northesk. Educated at Eton College, he succeeded his father as Duke of Montrose in 1742. 
Montrose married Lady Lucy Manners, daughter of John Manners, 2nd Duke of Rutland on 28 October 1742. They had two children: Lady Lucy Graham, who married Archibald Douglas, 1st Baron Douglas, and James Graham, 3rd Duke of Montrose, who succeeded.
He served as Chancellor of the University of Glasgow from 1743 to 1780. He died at age 78 at Twickenham, Middlesex, England.
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