Genus of spiders
Linothele is a genus of curtain web spiders that was first described by Ferdinand Karsch in 1879. All but one of the described species are from South America (Bolivia, Brazil, Colombia, Ecuador, Peru and Venezuela). The exception is "L. septentrionalis" from the far-away Bahamas, although it has certain features that suggest it may belong in another genus. Additionally, an undescribed species of "Linothele" is known from Panama.
"Linothele" females are stouter and tend to be more conspicuously colored than males. They make relatively complex webs that in most species are on or near the ground, mudbanks or rock walls (a few are arboreal), with females spending most of their life in a tunnel-like retreat. The male may wander and often inhabits a smaller web near a female's. The webs of "Linothele" are commonly co-inhabited by tiny kleptoparasitic spiders of the genus "Mysmenopsis".
Venom.
In humans, bites from "Linothele" typically cause mild pain and a numbness/tingling feeling that can last for a few days. They are generally reluctant to bite and will attempt to flee, but some species, especially those from dry regions, tend to be more defensive.
The venom of "Linothele" sp has a LD-50 dose of 0.6 mg/kg in laboratory mice. Two toxins, both of low molecular weight, were isolated in the venom, Ls1 and Ls2. These two toxins have been shown to be quite lethal to laboratory mice by injection into the cerebroventricular region. The lethal dose of Ls1 and Ls2 is 24 and 19 μg/kg respectively, both toxins represent 0.21% and 0.43% of the weight of the whole venom.
Species.
As of  2024[ [update]] it contains 66 species:
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References.
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