Exodeoxyribonuclease (lambda-induced) (EC 3.1.11.3, lambda exonuclease, phage lambda-induced exonuclease, "Escherichia coli" exonuclease IV, "E. coli" exonuclease IV, exodeoxyribonuclease IV, exonuclease IV) is an exonuclease. This enzyme catalyses the following chemical reaction
 Exonucleolytic cleavage in the 5′- to 3′-direction to yield nucleoside 5′-phosphates
This enzyme has preference for double-stranded DNA (dsDNA). This means that it degrades a single strand of dsDNA, primarily any strand which has a phosphate at its 5' end.
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