Protein-coding gene in the species Homo sapiens
Probable DNA dC- ;dU-editing enzyme APOBEC-3D is a protein that in humans is encoded by the "APOBEC3D" gene.
This gene is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1 and inhibit retroviruses, such as HIV, by deaminating cytosine residues in nascent retroviral cDNA.
References.
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Identification of APOBEC3DE as another antiretroviral factor from the human APOBEC family.
Dang Y, Wang X, Esselman WJ, Zheng YH.
J Virol. 2006 Nov;80(21):10522-33. doi: 10.1128/JVI.01123-06. Epub 2006 Aug 18.
Further reading.
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