The Pseudomon-"groES" RNA motif is a conserved RNA structure identified in certain bacteria using bioinformatics. It is found in most species within the family Pseudomonadaceae, and is consistently located in the 5' untranslated regions (5' UTRs) of operons that contain "groES" genes. RNA transcripts of the "groES" genes in "Pseudomonas aeruginosa" where shown experimentally to be initiated at one of two start sites, from promoters called "P1" and "P2" (see diagram). The Pseudomon-"groES" RNA is in the 5' UTR of transcripts initiated from the P1 site, but is truncated in P2 transcripts. "groES" genes are involved in the cellular response to heat shock, but it is not thought that the Pseudomonas-"groES" RNA motif is involved in heat shock regulation. However, it is thought that the motif might regulate "groES" genes in response to other stimuli.
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