The enzyme pyridoxal phosphatase (EC 3.1.3.74) catalyzes the reaction
pyridoxal 5′-phosphate + H2O formula_1 pyridoxal + phosphate
This enzyme belongs to the family of hydrolases, specifically those acting on phosphoric monoester bonds. The systematic name is pyridoxal-5′-phosphate phosphohydrolase. Other names in common use include vitamine B6 (pyridoxine) phosphatase, PLP phosphatase, vitamin B6-phosphate phosphatase, and PNP phosphatase. This enzyme participates in vitamin B6 metabolism.
Structural studies.
As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes 2CFR, 2CFS, 2CFT, 2OYC, 2P27, and 2P69.
References.
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