The "mraW" RNA motif is a conserved, structured RNA found in certain bacteria. Specifically, it is predicted in many, though not all, species of actinobacteria, and especially within the genus "Mycobacterium". Structurally, the motif consists of a hairpin with a highly conserved terminal loop sequence (red nucleotides in diagram at right). "mraW" RNAs are consistently in the presumed 5' untranslated regions of "mraW" genes. These "mraW" genes likely form operons with immediately downstream "ftsI" genes, and multiple types of "mur" genes. These genes are associated with peptidoglycan synthesis, and it was hypothesized that the "mraW" RNA motif might regulate these genes.
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