Protein-coding gene in the species Homo sapiens
Nuclear receptor coactivator 6 is a protein that in humans is encoded by the "NCOA6" gene.
Function.
The protein encoded by this gene is a transcriptional coactivator that can interact with nuclear hormone receptors to enhance their transcriptional activator functions. The encoded protein has been shown to be involved in the hormone-dependent coactivation of several receptors, including prostanoid, retinoid, vitamin D3, thyroid hormone, and steroid receptors. The encoded protein may also act as a general coactivator since it has been shown to interact with some basal transcription factors, histone acetyltransferases, and methyltransferases.
Interactions.
NCOA6 has been shown to interact with:
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References.
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Further reading.
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External links.
"This article incorporates text from the United States National Library of Medicine, which is in the public domain."