Protein-coding gene in the species Homo sapiens
Mannosyl-oligosaccharide glucosidase is an enzyme that in humans is encoded by the "MOGS" gene.
Glucosidase I is the first enzyme in the N-linked oligosaccharide processing pathway. GCS1 cleaves the distal alpha-1,2-linked glucose residue from the Glc(3)-Man(9)-GlcNAc(2) oligosaccharide precursor. GCS1 is located in the lumen of the endoplasmic reticulum.
GCS1 may also refer to "generative cell specific 1", also called HAP2 (hapless2), a gene of lower eukaryotes which is thought to be responsible for gametes fusion .
References.
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Further reading.
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