The enzyme endoglycosylceramidase (EC 3.2.1.123) catalyzes the following chemical reaction:
oligoglycosylglucosylceramide + H2O formula_1 ceramide + oligoglycosylglucose
This enzyme belongs to the family of hydrolases, specifically those glycosidases that hydrolyse "O"- and "S"-glycosyl compounds. The systematic name is oligoglycosylglucosylceramide glycohydrolase. Other names in common use include endoglycoceramidase, EGCase, and glycosyl-"N"-acetyl-sphingosine 1,1-β--glucanohydrolase.
Structural studies.
As of late 2007, 6 structures have been solved for this class of enzymes, with PDB accession codes 2OSW, 2OSX, 2OSY, 2OYK, 2OYL, and 2OYM.
References.
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