Protein-coding gene in the species Homo sapiens
Ubiquitin-associated and SH3 domain-containing protein B is a protein that in humans is encoded by the "UBASH3B" gene.
This gene encodes a protein that contains a ubiquitin associated protein domain at the N-terminus, an SH3 domain, and a C-terminal domain with similarities to the catalytic motif of phosphoglycerate mutase. The encoded protein was found to inhibit endocytosis of epidermal growth factor receptor (EGFR) and platelet-derived growth factor receptor.
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Further reading.
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