 
South Dakota Initiated Measure 27 was a 2022 voter initiative to legalize non-medical cannabis in the U.S. state of South Dakota. The initiative was certified by the South Dakota Secretary of State for the 2022 ballot on May 25, 2022. South Dakotans for Better Marijuana Laws (SDBML) organized the petition drive, and it was opposed by Protecting South Dakota Kids.
The initiative received a 52.92% no vote in the November 2022 election, and did not become law.
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