Clarkefield () is a town in Victoria, Australia, north-west of Melbourne's Central Business District, located within the City of Hume and the Shire of Macedon Ranges local government areas. Clarkefield recorded a population of 303 at the 2021 census.
Clarkefield was occupied as pastoral run, and it was named after the pastoralist, Sir William Clarke. The Clarkefield hotel and stables were established in 1857 and are now listed as heritage properties. The first school opened here in 1890.
The Post Office opened on 1 January 1862 and was known as Lancefield Road until 1881, Lancefield Junction until 1926 and closed in 1982.
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