The 1888 Missouri State Auditor election was held on 6 November 1888 in order to elect the state auditor of Missouri. Democratic nominee and incumbent State Treasurer of Missouri James M. Seibert defeated Republican nominee George W. Martin, Union Labor nominee William H. Noerr and Prohibition nominee James S. Cobban.
General election.
On election day, 6 November 1888, Democratic nominee James M. Seibert won the election by a margin of 25,079 votes against his foremost opponent Republican nominee George W. Martin, thereby retaining Democratic control over the office of state auditor. Seibert was sworn in as the 19th state auditor of Missouri on 14 January 1889.
Results.
! scope="col" colspan="2" style="width: 15em" |Party
! scope="col" style="width: 17em" |Candidate
! scope="col" style="width: 5em" |Votes
! scope="col" style="width: 3.5em" |%
! colspan="3" style="text-align:right;" | Total votes
References.
 ;templatestyles src="Reflist/styles.css" / ;