Tishomingo Hotel in Corinth, Mississippi was a hotel built in 1859, used as a military hospital during the American Civil War. It was burned down by Confederate forces in 1865. 
The two-story hotel was built in 1859 by Swiss architect Martin Siegrist. The hotel had a prime location, close to the railroad depot. In the backyard stood the hotel kitchen in a separate building, as well as a number of outbuildings. 
During the war it became a military hospital of both contending armies. First as a Confederate hospital after the Battle of Shiloh in April 1862, and then as a Union hospital after Battle of Corinth in October the same year. It was later used as a shelter for escaped slaves. 
In 1865 Corinth briefly fell into Confederate hands again, and the hotel was used as a supply magazine. When leaving town, the Confederate army under John B. Hood burned the hotel, in order to prevent the Union army from taking control over the supplies. 
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