The Debré family is a French family including several prominent politicians and physicians. The family's ancestor, rabbi Simon Debré, was born in Westhoffen, Alsace. His ancestors came from Harburg, Bavaria
 Simon Debré (1854–1939), rabbi
 x 1882 Marianne Trenel (1860–1949)
 ├── ; Robert Debré (1882–1978), physician 
 │ x 1908 Jeanne Debat-Ponsan (1879–1929), daughter of Édouard Debat-Ponsan (1847 - 1913)
 │ ├── ; Michel Debré (1912–1996), politician 
 │ │ x 1936 Anne-Marie Lemaresquier (1912-)
 │ │ ├── ; Vincent Debré (1939-), businessman
 │ │ │ x Isabelle de Lacroix-Vaubois (1957-)
 │ │ ├── ; François Debré (1942-2020), journalis
 │ │ │ └── ; Constance Debré, novelist 
 │ │ ├── ; Bernard Debré (1944-2020), physician and politician
 │ │ │
 │ │ └── ; Jean-Louis Debré (born 1944), politician
 │ │ └── ; Guillaume Debré, journalist 
 │ ├── ; Claude Debré (1913- ), physician
 │ │ x 1942 Philippe Monod-Broca (1918–2006), surgeon
 │ └── ; Olivier Debré (1920–1999), painter
 │
 └── ; Claire Debré (1888–1972)
 x 1907 Anselme Schwartz (1872–1957), surgeon and member of the "Académie des sciences"
 └── ; Laurent Schwartz (1915–2002), mathematician
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