The 1950 Missouri State Auditor election was held on 7 November 1950 in order to elect the state auditor of Missouri. Democratic nominee and incumbent state auditor W. H. Holmes defeated Republican nominee William Barton, Progressive nominee Howard R. Edsell, Christian Nationalist nominee O. M. Tanner, Prohibition nominee Bertha M. Boutell, Socialist nominee Elizabeth Erbe and Socialist Labor nominee Theodore Baeff.
General election.
On election day, 7 November 1950, Democratic nominee W. H. Holmes won re-election by a margin of 89,525 votes against his foremost opponent Republican nominee William Barton, thereby retaining Democratic control over the office of state auditor. Holmes was sworn in for his second term on 8 January 1951.
Results.
! scope="col" colspan="2" style="width: 15em" |Party
! scope="col" style="width: 17em" |Candidate
! scope="col" style="width: 5em" |Votes
! scope="col" style="width: 3.5em" |%
! colspan="3" style="text-align:right;" | Total votes
References.
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