The 1973 Manchester Exchange by-election of 27 June 1973 was held after the death of William Griffiths on 14 April of the same year. The Labour Party won the by-election in what had traditionally been a safe seat.
Due to an administrative oversight, the by-election was held on a Wednesday, rather than the Thursday which had been usual since the mid-1960s. Only one by-election since has been held on a day other than a Thursday, the 1978 Hamilton by-election.
Results.
! scope="col" colspan="2" style="width: 130px"|Party
! scope="col" style="width: 17em"|Candidate
! scope="col" style="width: 5em"|Votes
! scope="col" style="width: 3.5em"|%
! scope="col" style="width: 3.5em"| ;templatestyles src="Template:Tooltip/styles.css" / ;±%
! colspan="3" style="text-align: right; margin-right: 0.5em" | Majority
! colspan="3" style="text-align: right; margin-right: 0.5em" scope=row | Turnout
! style="text-align:right;" | Swing
References.
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