The 1888 Missouri lieutenant gubernatorial election was held on 6 November 1888 in order to elect the lieutenant governor of Missouri. Democratic nominee Stephen Hugh Claycomb defeated Republican nominee G. H. Wallace, Prohibition nominee William C. Wilson and Union Labor nominee J. C. Seabourn.
General election.
On election day, 6 November 1888, Democratic nominee Stephen Hugh Claycomb won the election by a margin of 23,103 votes against his foremost opponent Republican nominee G. H. Wallace, thereby retaining Democratic control over the office of lieutenant governor. Claycomb was sworn in as the 21st lieutenant governor of Missouri on 14 January 1889.
Results.
! scope="col" colspan="2" style="width: 15em" |Party
! scope="col" style="width: 17em" |Candidate
! scope="col" style="width: 5em" |Votes
! scope="col" style="width: 3.5em" |%
! colspan="3" style="text-align:right;" | Total votes
References.
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