Multiple parameters will be collected (outlined page 2) for descriptive statistics and bivariate analysis, testing for an association of osteoporosis and clinicopathologic and laboratory risk factors. These will be compared between the treatment and control arms to ensure both groups are representative and without potential confounding variables. Paired t-tests will be performed using statistical software (SAS) for the comparison of baseline, 6 and 12-month BMD values, with a significance level of 0.05 and a power of 0.80.