Ethical clearance will be taken from Ethical Review Committees of Mekelle University. A written co-operating letter will be taken from the prison- administrators of each region. The participants will be included in the study after they have provided written informed consent. Patients who are confirmed to have tuberculosis will be referred to get treatment. The confidentiality of both paper-based and electronic patient data will also be safeguarded throughout the research activities and even after the research is completed.