To evaluate the association of changes in HbA1c levels from baseline with plasma DHA/EPA, linear regression analyses are carried out at week16 in each treatment group. We construct multivariable logistic regression models to assess whether plasma DHA/EPA is independently associated with HbA1c reduction. We calculate Spearman correlation coefficients between changes in HbA1c and the following variables: compliance with diet therapy, estimated intakes of various food items including fish, and the clinical characteristics of the patients (age, sex, body mass index, duration of diabetes, baseline HbA1c) using IBM SPSS Statistics 22 (SAS Institute Inc., Cary, NC, USA).