Discoid lupus erythematosus is the most common form of the chronic forms of cutaneous LE. It is a very chronic inflammatory disease consisting of fixed, indurated, erythematous papules and plaques that are often distributed on the head and neck. Without intervention, dLE lesions may last for many years and are associated with extensive scarring. When dLE occurs on the scalp, permanent scarring and alopecia may result. If the initial work-up of a patient with localized lesion of dLE does not reveal evidence of sLEsLE, the risk of developing sLEsLE is low, about 5%. When dLE lesions are generalized, this risk is slightly higher. However, dLE lesions are not uncommon in patients with an established diagnosis of sLEsLE. About 25% of sLEsLE patients will develop lesions of dLE at some time in the course of their disease (Fitzpatrick, 1996).