Summary: We propose a prospective, randomized, controlled trial of an intensive deworming care package versus standard of care in a cohort of HIV-1 seropositive adults who do not yet meet criteria for antiretroviral medications. Participants will be randomized into one of two treatment arms. Arm 1 will receive an intensive regimen of anti-helminthic therapy consisting of albendazole every three months for two years and praziquantel at enrollment and at one year of follow up. Arm 2 will receive symptomatic diagnosis and treatment of helminth infection as is current standard of care in Kenya. The primary objectives of this study are to evaluate changes in CD4 count and HIV-1 RNA over the two years of follow up in each of the study arms.