In osmotic diarrheas, osmotically active substances draw fluids from the plasma into the jejunum along the osmotic gradients through the highly permeable jejunal epithelium. Examples of chronic diarrhea due to an osmotic cause include malabsorption states such as celiac disease, bacterial overgrowth, osmotic laxatives including salts, and lactulose and maldigestion as occurs in disaccharidase deficiency and pancreatic exocrine insufficiency.Osmotic diarrheas might result in steatorrhea (passage of fat in to the stool). (Pardi etal., 2002)