For most surgical procedures a depth of neuromuscular block of 1-2 twitches after TOF-stimulation is sufficient to avoid unwanted muscular activity. At reappearance of T2, the anesthesiologist might decide to either give (another) maintenance dose of rocuronium or vecuronium when surgery continues, to await spontaneous recovery of neuromuscular block or to reverse the neuromuscular block. Org 25969 has been shown in previous trials to greatly reduce the time to full recovery when administered at reappearance of T2, both after rocuronium- and vecuronium-induced neuromuscular blockade. The current trial 19.4.208A was conducted in Japan and set up to establish the dose-response relationship of Org 25969 given during sevoflurane anesthesia at reappearance of T2 after rocuronium or vecuronium in Japanese subjects. In addition to recovery time, also pharmacokinetics and safety of Org 25969 were to be evaluated.