3.12 DATA ANALYSIS 3.12.1 DATA MANAGEMENT All case record forms (CRF) will be double-entered daily using EpiData 3.1 software (Odense, Denmark), merged (with verification of inconsistencies) and analysed using Stata (Stata Corporation, USA) statistical software. An interim analysis of early treatment failure will be carried out once all the participants have reached day 3 and their blood smear results are available. This is to assess at an early stage whether the non-inferiority hypothesis regarding early treatment failure should be rejected. At the end of the study analysis, all CRFs and other source data (consent forms, laboratory registers, screening forms, etc) will be stored securely at the capital level. Data will also be submitted to the WWARN database for the international monitoring of anti-malarial drug resistance. A copy of CRFs will also be stored for at least 5 years at MSF-OCA in Amsterdam. The principal investigator is responsible for keeping all screening forms, the case report form and the completed subject identification code list in a secure location.