We aim to undertake an open labeled randomised trial at two sites: the IDI which is an urban center of excellence in HIV care, and Kasangati Health Center, which is a peri-urban public health care facility. The project aims to enroll patients starting ART, already established on first line ART or switching to second line ART. We will include special populations including pregnant women, discordant couples and young people. The estimated length of the project is 30 months. The technology to be evaluated in this study is based on CONNECT FOR LIFETM m-health technology (CFL2015.01 or higher). CFL2015.01 provides text messages or Interactive Voice Response (IVR) functionalities, a technology that allows a computer to interact with humans through the use of voice and tones input via keypad, including pill reminders, clinic visit reminders, health tips and functionality to support symptom reporting.