- Exclusions: the following supportive care medications will be allowed: dexamethasone, aprepitant, fosaprepitant, and ondansetron; oral pain medications such as hydrocodone, oxycodone taken on an as needed basis are also permitted; transdermal products designed for systemic delivery must be assessed for interaction potential; topical products not designed to provide systemic delivery (including inhaled products, ophthalmologic products and transvaginal preparations) do not need to be considered since they do not have appreciable systemic absorption