INTRODUCTION - Osteoporosis is a common disorder with many predisposing factors including hypogonadism from a variety of causes. Prostate cancer is the second most common malignancy in men. The standard treatment for men with advanced prostate cancer is hormonal manipulation in order to decrease testosterone levels which renders a man hypogonadal. There is an increasing body of literature that suggests men with prostate cancer treated with hormonal manipulation develop osteoporosis and associated complications more commonly than aged matched controls. With the increasing incidence of prostate cancer and the increasing indications with hormonal therapy use in advanced prostate cancer, osteoporosis in these men is a major health concern.Hormonal manipulation in order to obtain castrate levels of testosterone can be achieved with bilateral orchiectomy, Luteinizing Hormone Releasing Hormone agonists (LHRHA) and steroidal antiandrogens combined with mini doses of estrogen based therapy. Nonsteroidal antiandrogens are also used in the management of advanced prostate cancer however, on their own, are not enough to suppress testosterone. The data on exactly how common and severe a problem osteoporosis is in men treated with different forms of hormonal manipulation is sparse and because of the lack of data, there is currently no accepted standard of care in the investigation and management of osteoporosis in these men. The researchers propose to start with a pilot study to first determine the prevalence of osteoporosis in 6 different populations of men with advanced prostate cancer, (1) newly diagnosed, (2) treated with orchiectomy, (3) treated with an LHRHA, (4) treated with steroidal antiandrogen therapy, (5) treated with nonsteroidal antiandrogen based therapy, (6) treated with complete androgen blockade (LHRHA plus a nonsteroidal antiandrogen).