Zunini et al,retrospectively studied 122 children undergoingcraniofacial surgery. Out of 122 patients 63 received only Normal saline (NS group) whereas 59 received Ringer lactate (RL group). Acid-base balance and electrolytes were measured at 1-2 hrs post-induction (P1) and 2-4 hrs post induction (P2). This study showed that the incidence of metabolic acidosis was 45% (44 patients) in P‐1 and 60% (61 patients) in P‐2 time period. Acidosis was more frequent in NS group than in the RL group in both periods: 66% and 80% in NS versus 26% and 37% in RL group (P = 0.015 for P‐1 and P = 0.027 for P‐2). The incidence of severe acidosis (pH <= 7.25) was also larger in those receiving NS (39%) than in those receiving RL (8%). Hyponatremia (Na <135 mmol/L) was observed in 40% (NS) and 26% (RL) of the cases during P‐1 and in 52% (NS) and 50% (RL) of the cases during P‐2 time period. No statistically significant difference was found in the incidence of hyponatremia between the groups. Overall the incidence of metabolic acidosis and hyponatremia was less in RL group compared to NS group.