Immunological examination (1, 2, 12, 60 days). CD45 PC7, CD3 FITC, CD16/32 PE NK, CD4 ECD, CD25 PE, CD19 PE, MHCII (I-A) PerCP, TLR2, TLR4, TLR7, TLR3, TLR9, IL1B, IL-2, IL-4, IL-6, IL-8, IL-10, IFN-gamma, IFN-alpha.