Moreover, according to the same document [lines 286-306] T reg DLI SHOULD BE REGARDED as administered for HOMOLOGOUS USE. Indeed, as outlined in "Reflection paper on classification of advanced therapy medicinal therapy" the cells harvested and separated by a simple selection method, and re-administered to fulfil their same essential function will generally be regarded as homologous use. The same essential function for a cell population means that the cells when removed from their original environment in the human body are used to maintain the original function in the same anatomical or histological environment.