Your doses of all chemotherapy that is given in this study may be increased or decreased depending on your organ function and side effects. Throughout intensive chemotherapy and maintenance therapy, you will also receive other drugs, fluids, or blood products (such as antibiotics, antiemetics, antacids, saline, platelets, and plasma), including allopurinol (by mouth) or rasburicase (by vein), to help protect your body against tumor lysis syndrome. This is a condition brought on by the death of large tumors, which causes damage to kidneys.