In each period, a total of 18 blood samples will be collected using pre-labelled 6ml K3EDTA vacutainers as per the following schedule: 0.0 (pre-dose) and 0.5, 1, 2, 2.5, 3, 3.5, 4, 4.5, 5, 6, 7, 8, 10, 12, 16, 24 and 30 hours after dosing. The volunteers will be housed for 36 hours after dosing. The bioanalyst will be blinded to study treatments received by the subject.