1. Objectives The project aims the integration for the first time in Romania of modern monitoring equipment for pro-oxidative, pro-inflammatory status and the energetic-metabolic necessary specific to the departments of anesthesia and intensive care, the clinical and laboratory data, genetic / epigenetic analyzes and existing information for the modulation and optimization of the intensive care for polytrauma patients. This way, the prospect of developing a decision support module for doctors to improve indices of mortality and morbidity in this area will be created. Reducing mortality and increasing quality of care is possible by providing a modern and complex monitoring system for critically ill polytrauma patient followed essentially by the acquisition, interpretation and synthesis in time of these biological signals and correlation with other clinical and laboratory data useful in modulating intensive care.