- Contraindications as listed in the local Summary of Product Characteristics. - Scar, fibrosis, or atrophy involving the center of the fovea in the study eye. - Any prior or concomitant therapy with any other agent (including among others, anti-VEGF agents and photodynamic therapy) to treat wet AMD in the study eye. - Patients with previous exposure to systemic anti-VEGF treatment. - Patients participating in an investigational program with interventions. - Previous macular surgery, including laser, for any retinal pathology in the study eye.