2.2 DRUG MANUFACTURE, BLINDING AND SUPPLY OF TRIAL MEDICATION Atorvastatin will be purchased on the open market. Placebo will be manufactured specially to match the IMP. Capsules and packaging will be identical in appearance for both IMP and placebo. DBcaps® capsules have a unique locking mechanism to help with assuring the integrity of the blind will be used for over encapsulation of both active and placebo treatments. The blinding process will involve encapsulating the active tablet, complete removal of the original manufacturer's label and replacement with the clinical trial label bearing the randomisation number which will be used as the pack identification. Outer pack labelling will be identical for IMP and placebo and will be in compliance with regulations.