Results in death; Is life-threatening (immediate risk of death); Requires inpatient hospitalization or prolongation of existing hospitalization; Results in persistent or significant disability/incapacity (substantial disruption of the ability to conduct normal life functions); Results in congenital anomaly/birth defect, 8.3. Severity Assessment This is not an intervention study and no specific drug will be investigated. Patients will be enrolled in the study to document in details the outcomes occurring during their care at the IDI clinic.