Haemoglobin concentration will be determined on day 0, 3 and 42 using a haemocueTM At the same time that blood sampling for microscopy is done on Day 0, exactly 200μL of blood will also be taken for in vitro culturing from 50 patients. The blood will be put into medium and grown in vitro in an incubator at 37 ˚C. When a culture is established it will be frozen in liquid nitrogen for transport to Sweden or Portugal where extensive drug assays will be carried out.