Despite continuing dissemination, many challenges remain to maximize the benefits offered by testing and refined treatment selection. TAILORx results will continue to strengthen the evidence for clinical utility and increase testing rates. An effective intervention should be ready to respond to this increasing need. Communication can influence more proximal outcomes, including patient comprehension of their disease and its treatments, treatment preferences and satisfaction, involvement in care decisions as well as longer-term outcomes of treatment adherence and quality of life. This trial will test the feasibility and impact of a patient activation intervention to support effective integration of the Recurrence Score into clinical encounters and treatment decisions. Patient activation interventions utilizing a question prompt list (QPL) can impact proximal outcomes of preferences, comprehension, satisfaction and involvement. In Phase 1, investigators will further refine a draft QPL based on in-depth interviews with patients (N = 20) and medical oncologists (N = 10). In Phase 2, women with newly-diagnosed breast cancer will be recruited to a single-arm trial (N = 75) to demonstrate feasibility and preliminarily assess the impact of the QPL on key outcomes. Aims are to: