Eligible subjects will have an initial one-month run-in period on Ortho-Cyclen®. In addition to washing out any previous hormone exposure, this washout will serve as a compliance hurdle that will help in selecting subjects that are willing to undergo the discipline of the study. Washouts between treatments will not be performed in order to provide continuous contraception for the study subjects and facilitate compliance once subjects are randomized into the study. As each treatment period will last two months, the first month of each two-month treatment period will be considered as the washout from the previous treatment protocol. The second month of each two-month treatment period will be the investigative month.