4. Confirmed diagnosis of inflammatory breast cancer according to international consensus criteria: (1) Onset: Rapid onset of breast erythema, edema, and/or peau d'orange, and/or warm breast, with or without an underlying breast mass (2) Duration: History of such findings no more than 6 months (3) Extent: Erythema occupying at least 1/3 of whole breast (4) Pathology: Pathologic confirmation of invasive carcinoma