Currently long-term follow-up data on patients who have undergone FMT is lacking. There are only scattered reports documenting the alteration of the enteric microbial composition and function status post transplantation. This study will significantly increase understanding of the short and long term safety, efficacy, and tolerability of FMT. It will also enable researchers to assess the change in the fecal microbiome after transplantation. Answers to these questions may lead to identification of key bacterial taxa to target future therapy.