We propose to apply 31P-MRS to the important problem of statin-associated myalgia to measure the rate of PCr recovery following exercise in statin users before and after statin therapy (with concurrent randomization to ubiquinol or placebo). Ultimately, we believe this work could have an important impact on the care and management of those with statin myalgia by 1) elucidating the relationship between muscle symptoms and mitochondrial function through a quantifiable, validated and non-invasive biochemical index and 2) by determining the effects of supplemental ubiquinol on mitochondrial function and muscle side effects in statin users.