One of the major limitations of psychiatric research is the necessity to use indirect methods to study neuronal functions. Among these, studies of transformed lymphocytes are an invaluable tool. Epstein Barr virus (EBV) transformed lymphoblasts can be used for a variety of purposes including in vitro studies of gene expression and investigations of cellular responses to pharmacological treatment. They can be kept and re-grown as needed and can often serve as a backup supply for DNA for genetic analyses. For these reasons, lymphoblasts cell lines (LCLs) have been collected and used by a number of research groups, including our own.