- Adequate organ system function defined as: Hematologic: Absolute neutrophil count (ANC) >=1.0 X 10/meter (m)^9/L, Hemoglobin >=8.0 g/dL, Platelets >=50 X 10 m^9/L, Prothrombin time/ International normalization ratio (PT/INR) <=1.5; Hepatic: Total bilirubin =<1.5 X Upper limit of normal (ULN) (isolated bilirubin >1.5 X ULN is acceptable if bilirubin is fractionated and direct bilirubin <35%), Aspartate aminotransferase (AST) and Alanine aminotransferase (ALT) =<1.5 X ULN, Serum Calcium corrected for albumin: =<12 mg/mL (=3 mmol/L); Cardiac: Corrected QT interval duration (QTc) interval <470 milliseconds (msecs), Left Ventricular Ejection Fraction (LVEF) (Echocardiogram [ECHO] or Multigated acquisition scan [MUGA]) >=50%, Renal: Serum Creatinine <2.5 mg/dL, Estimated glomerular filtration rate (GFR) or 24-hr urine creatinine clearance >=30 mL/ minute [min] (Estimated glomerular filtration rate will be calculated by the Modification of Diet in Renal Disease [MDRD] equation. When both a calculated and 24-hr creatinine clearance are available, the 24-hr value will be used). Note: Laboratory results obtained during Screening should be used to determine eligibility criteria. In situations where laboratory results are outside the permitted range, the investigator may opt to retest the subject and the subsequent within range screening result may be used to confirm eligibility