3. The difference in the excellent and good rate between the trial and control groups and its 95%CI will be calculated. The lower limit greater than -10.0% can be considered as non-inferiority. Measurement data will be compared using two-sample t-test or Mann Whitney U rank sum test between the two groups. Intergroup comparison will be conducted using Pearson's chi-squared test or Fisher's exact test. Ranked data in both groups will be analyzed using Wilcoxon rank-sum test or Cochran-Mantel-Haenszel test.