Currently, maternal fetal monitoring is limited, as it is difficult to "see" what is going on in the placenta (maternal-fetal interface) without invasive measures such as placental biopsy or amniocentesis. Our preliminary study from term pregnancies has shown that a specific correlation of an intrauterine cytokine may be reflected in one noninvasive site but not another, depending upon the type of cytokine and the compartment from which it is secreted. Therefore, our second goal for this study is to identify inflammatory markers in non-invasive maternal compartments (such as saliva, blood, urine, and/or cervical and vaginal secretions) that have a strong association with placenta/fetal membranes at the time of preterm birth ≤ 32 weeks gestation.