Relevance and strategic approach Prostate Cancer (PCa) is the most common cancer in men and the second leading cause of cancer deaths in western countries. Known risk factors are advanced age, ethnic origins and positive family history of the disease (1). There are considerable ethnic disparities in PCa risk, with a 60% higher incidence rate among African-American (AA) men as compared with European-American (EA) men (2). Similarly, in the French West Indies, where at least 90% of inhabitants are of African descent, the incidence of PCa is twice as high as in the rest of France (3). Many lifestyles, environmental and occupational related risk factors including obesity, diet, medications and pesticides have been implicated in PCa etiology, but their roles remain unclear (4). Current research suggests that there is a complex interplay of genetic and environmental factors that have a causative role in PCa.