It is also expected that this study will provide new information on the natural history of Chikungunya infection in neonates as well as on the pathophysiology of viral transmission (transplacentally during labor or/and during fetal progression into the genital tract). Actually comparison of quantitative CHIKV RT PCR titers in mother's urine at delivery, placenta, and neonate's blood and other fluids, as well as determination of placental microperfusion markers (placental alkaline phosphatase on cord blood) should shed light on this issue.