We expect that results from this study will provide an objective basis for a larger, formal randomized controlled study combining the two therapies. Our long term goals are to maximize the benefits of a modern vision rehabilitative therapy, lay the groundwork for neurophysiological correlates associated with the recovery of visual function following brain injury and propose possible refinements for future neurorehabilitation strategies. Data from our collaborators at Columbia University Medical Center as well as others indicate that a 6 month course treatment therapy of VRT can lead to dramatic improvements in visual function (as quantified by increases in functional visual field) (Kasten et al., 1998; Kasten et al., 2006). TDCS is well known to bring about transient positive changes in both functional as well as electrophysiological measures of cortical brain function. If overall visual function can be further enhanced via a combined synergetic effect of VRT and TDCS, we will conduct a larger randomized controlled study. If there is no enhancement effect with combined TDCS and VRT, we will need to reconsider factors as to why this is the case. For example, a lack of enhancement effect could be related to patient selection including the degree and profoundness of vision loss prior to treatment, the age of the individual and duration of the insult, as well as their level of motivation in participating with the computer-based training program. Other considerations include longer combined treatment duration.