During exercise 'Respiratory Muscle Metaboreflex' will lead to sympathetically mediated vasoconstriction of limb locomotor muscle, less blood and oxygen supply to active limbs muscle there by locomotor muscle fatigue occurred. Quadriceps twitch forces evoked by magnetic stimulation of femoral nerve will be assessed to measure locomotor muscle fatigue at identical exercise time points during CWR test before and after the intervention. With this technique, the investigators will be able to assess whether the onset of locomotor muscle fatigue is delayed after IMT.