- Phase Ia (dose-escalation) - patients with a histologically confirmed diagnosis of advanced, unresectable, and/or metastatic solid tumours (any type). Phase Ib (dose expansion - patients with a confirmed diagnosis of select advanced, unresectable, and/or metastatic solid tumours (Non Small Cell Lung Cancer, bladder cancer, melanoma, gastric cancer, ovarian cancer, Triple Negative Breast Cancer, and Renal Cell Carcinoma). All patients must have measurable lesions according to Response Evaluation Criteria in Solid Tumours (RECIST) v1.1 and Immune-Related Related Response Evaluation Criteria in Solid Tumours (irRECIST).