This randomized clinical trial involved the restoration and evaluation of 83 (target enrollment was 80) non-carious cervical lesions (NCCLs) using either the new two-component self-etch universal adhesive OptiBond XTR or a control dental adhesive, OptiBond FL, and a nano-hybrid composite restorative material, Herculite Ultra. OptiBond XTR is a two-component self-etch, filled, fluoride releasing, light-cured bonding agent designed for the universal bonding of direct and indirect restorations. The study design was based on the American Dental Association Acceptance Program Guidelines for Dentin and Enamel Adhesive Materials.