Study FVF2428g was a Phase I/II, single masked, multicenter study of the safety, tolerability, and efficacy of multiple dose intravitreal injections of ranibizumab in combination with verteporfin PDT in subjects with neovascular AMD. Data show that the combination of ranibizumab and verteporfin PDT had a good safety profile in the study population, and the efficacy of ranibizumab and verteporfin PDT was better than that of verteporfin PDT alone.