MPS and GSS is scored as 0 = none; 1 = mild (present but not disturbing); 2 = moderate (disturbing but not hampering day time activities and/or sleep); and 3 = severe/intense (disturbing and hampering day time activities and/or sleep). Number of wheals are scored as 0 = none; 1 = mild (less than 20 wheals per 24 hours); 2 = moderate (21-50 wheals); and 3 = severe (more than 50 wheals).