In 1-10% of normally-responding patients, ovarian hyperstimulation syndrome (OHSS) occurs in which too many follicles develop, placing the woman at risk for hospitalization. Because a suboptimal number of follicles develop in women who respond poorly to ovarian stimulation therapy, we believe that the risk of ovarian hyperstimulation is extremely low to zero. However, because we cannot predict the outcome of initiating therapy on day 1 of the menstrual cycle, we cannot guarantee that hyperstimulation will not occur.