Study Conduct: Patients will be enrolled onto a sequence of receiving an oral dose of RAD001. The schedule of RAD001 will be either once daily or once weekly. Throughout the whole phase I and II study, an eligible patient will be randomized into either arm of daily or weekly schedule. In the phase I part, each cohort of dose level will have 3 patients. The dose of oral RAD001 will be initially fixed at 2.5 gm/day in daily schedule arm and at 20 mg/week in weekly schedule arm. One treatment course is defined as 4 weeks of RAD001 therapy. When no patient experiences dose-limiting toxicity (DLT) at certain level, subsequent patients would be randomized to the next dose level. When 1 out of 3 patients developed DLT, 3 additional patients would be treated with the same dose level. Three patients will be further recruited to the next dose level when none of that 3 additional patients experience DLT. No intra-individual dose-escalation will be performed. In the phase II part, Simon's optimal two-stage approach will be used in both daily and weekly schedules. If one responder is observed at the first stage of eighteen patients in either treatment schedule, further twenty-five patients will be accrued.