(1) 14 days: thiazide diuretics (2) 30 days: loop diuretics, lithium, , systemic corticosteroid (3) 3 months: calcitonin, cinacalcet hydrochloride, rhPTH(1-84) or N-terminal PTH or PTH-related peptide fragments or analogs (4) females only; changes in hormone replacement therapy within 3 months (5) 6 months: fluoride tablets, oral bisphosphonates, methotrexate growth hormone, digoxin; raloxifene or similar selective estrogen receptor modulators (6) 12 months: intravenous bisphosphonates, drug or alcohol abuse 3. History of a clinically significant disorder involving the cardiovascular, respiratory, renal, gastrointestinal, immunologic, hematologic, endocrine (with exception of the condition under study), or neurologic system(s) or psychiatric disease as determined by the Investigator.