. No studies are presently investigating the effect of long-term RIC on PAD in diabetes patients (Clinicaltrials.gov search 22nd of October 2015), the concept has however recently been presented in the literature . Two studies have addressed the acute effect of one RIC treatment on walking distance in non-diabetic patients with claudication. The results were inconclusive due to small sample sizes, but a trend towards improvement was shown. It is however likely that long-term RIC treatment is needed to show a beneficial effect of RIC on the pathology behind claudication - vascular and neuronal damage.