High dose therapy (HDT) and autologous hematopoietic cell transplantation (autoHCT) is considered standard therapy for younger, transplant eligible multiple myeloma (MM) patients. Mobilization of peripheral blood progenitor cells (PBPC) for HDT and autoHCT can be accomplished by using cytokines, most commonly granulocyte-colony stimulating factor (G-CSF), either alone or in combination with chemotherapy or plerixafor.