Cells from each tissue sample will be cultured in vitro. These cells will eventually be kept and frozen in this lab in a temperature locked freezer. The Research Assistant Professor will record subject information into a secure database in Pediatric Craniofacial Biology Laboratory. No information permitting personal identification of family members will be made public. No clinical descriptions that might permit personal identifications will be published, and all clinical information will be stored in secure computer files in the Pediatric Craniofacial Biology Laboratory, which are password protected. Specimens will be stored with assigned code numbers and information linking theses code numbers to the corresponding subjects' identities will also be kept in a password protected database. If a subject should decide to withdraw or be withdrawn from study participation, the linkage code to subject's identity and the specimen will be destroyed.