7.1.2.2 Follow-up CRF form (see: Follow-up Contact Case report (review) form (Follow-up CRF)) Every time a patient has a contact with the AMC (e.g. INR measurement or dosing instructions), the dosing staff or study nurse will ask questions by exactly following the case review form (CRF, 14.2). If the questions are answered with a "yes", the study nurse will without delay contact that particular patient for more detailed information (ie HCRU form, see: Event report form / Health Care resource utilization (HCRU)). The study nurse will then, as appropriate, collect necessary documents for the independent adjudication committee (IAC), see chapter 9.3.3. During each patient event, the following will be systematically checked by interviewing patients and reviewing the hospital chart for thromboembolism, bleeding events, concomitant medication, in particular antiplatelet agents such as aspirin or clopidogrel and NSAID use and compliance with monitoring 7.1.2.3 Observational period All patients will have a 5 day observational period after discontinuing from study.