Newer regional anesthesia techniques have been developed to improve pain control and patient satisfaction. These includes epidural blocks (thoracic and cervical), single injection thoracic PVB and intercostal nerve blocks. PVB during breast cancer surgery have been reported to decrease acute pain and opioid consumption immediately following surgery in multiple randomized clinical trials [4, 5, 6] and were superior over epidural blocks due to lower complication rate. A thoracic PVB is a well-established anesthetic technique and has been proven to be safe for mastectomies.