- Exclusion criteria for screening ECG (a single repeat is allowed for eligibility determination): Heart rate <45 and >100 beats per minute (bpm) for males and <50 and >100 bpm for females; PR Interval <120 and >220 milliseconds (msec); QRS Interval: <70 and >120 msec; and corrected QT (QTc) interval (Fridericia's) >450 msec.