Following a 10-hour overnight fast, subjects will be randomized as per predetermined randomization sequences to any of three study treatment arms in a ratio of 1:1:1 and then administered a single oral dose of study drug (A: metformin SR 1000 mg in fasting state, B: metformin SR 1000 mg in fed state, C: metformin SR 1000 mg/glimepiride 2 mg in fed state) in treatment period 1. In the subsequent two study periods, subjects will receive the other treatments, according to the randomisation schedule so that all subjects receive all treatments.