Statistical analysis Statistical analyses were performed with Statistica, version 12.5. (StatSoft, USA). Since the tested data did not meet the assumption of Gaussian distribution (evaluated with Shapiro-Wilk method), the non-parametric methods were applied. The Wilcoxon signed-rank test was used for evaluation of the differences between the initial values and the values obtained after the treatment, for factors of; body weight composition, blood pressure, and platelet aggregation. To evaluate differences and correlations between the two independent groups the Mann-Whitney U test and Spearman׳s rank correlation coefficient (Rs) were used, respectively. The data presented on graphs and tables included median and interquartile ranges. A p<0.05 was considered as significant.