Control condition for clients testing HIV negative through clinic-based recruitment and internal referrals includes a brief risk assessment, (which will occur prior to consenting of a subject on the study) conducted by the University of Chicago, CDPH clinic staff, and referral for additional STI testing and provision of information regarding other HIV prevention programming (including PrEP). Clients will receive low threshold intervention through the PrEP Line, a phone-based PrEP linkage intervention. The PrEPLine Linkage to Care Specialist (LTC) will establish contact with client, facilitate an initial interview to provide PrEP education, collect necessary patient information and build rapport. Once relevant information is collect, if the participant is interested and eligible for PrEP, LTC specialist will collaboratively determine most appropriate PrEP provider (based on location, insurance, and patient preference) and will offer to schedule initial PrEP appointment.