Methods of Analysis Baseline, demographic and safety data will be listed for all treatment groups. Summary statistics will be provided for each treatment group. The student T-test will be used to compare between mean values of continuous variables in either intervention groups, while the Chi-square test will be used to compare difference between categorical variables. The secondary endpoints will be analyzed using procedures similar to that described above for the primary endpoint. Multivariate logistic regression will be used to identify independent predictors associated with abstinence at week 24 and at week 52.