- Ability and willingness of participant to provide written informed consent. 2. Men and women age ≥18 to ≤70 years at study entry 3. Body mass index (BMI) ≥ 18 kg/m2 4. HCV RNA ≥ 10,000 IU/mL at Screening 5. HCV genotype 1a at Screening 6. Chronic HCV infection (≥ 6 months) documented by prior medical history 7. HCV treatment-naïve with no prior treatment with any interferon (IFN), RBV, or approved or experimental HCV-specific DAA