In prostatectomies, where pelvic lymph node dissection is a standard part of the procedure, there has been investigation into fluorescence guided lymph node mapping. Yuen et al utilised ICG guided node mapping in open prostatectomy. In their study, all lymph nodes identified by fluorescence were found to have metastases on pathology whereas non-fluorescent nodes were free from disease. A smaller, retrospective study comparing fluorescence guided lymph node dissection with standard lymph node dissection showed higher sensitivity and specificity in the fluorescence guided technique. Similar results were seen in an early, robotic prostatectomy study.