To ensure allocation concealment, the computer-generated assignment schedule will be held centrally and administered by 2 designated administrators who are not involved in the study. If a participant meets the inclusion criteria and provides informed consent, he or she will be entered into the study. Investigators will telephone the designated administrators, who after recording the patient's identification number, date of birth and disease activity score, will assign the next number in the series to determine allocation group. The assigned group will be recorded and implemented. Nobody will be able to alter the assignment. Participants in the telephone group will, however, retain the option to return to routine care through non-concordance with the allocated intervention.