HPV will be evaluated with the same HPV test used in regular screening: the Cobas 4800 HPV test (Roche Diagnostics) is a qualitative in vitro test that utilizes amplification of target DNA by real-time Polymerase Chain Reaction (PCR) for the detection of 14 high-risk (HR) HPV types in a single analysis. It is a qualitative multiplex assay that provides specific genotyping information for HPV types 16 and 18, while concurrently detecting the other 12 high-risk HPV types (31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 66 and 68) as a pooled result. ß-globin from cellular input is used as an internal control to assess specimen quality. The test is being performed on the completely automated cobas 4800 System (Roche Diagnostics), according to the manufacturer's instructions; a sample is considered positive according to the specific algorithm of the Cobas system software.