In this safety and feasibility study, 20 GBS patients will be enrolled for SVPE as per protocol criteria. Clinometric measurements (heart rate, blood pressure, temperature, oxygen saturation (SpO2), neurological examination) along with documentation of central line associated blood stream infection (CLABSI) and other complications related to central venous (CV) catheter will be conducted daily and throughout the course of SVPE until the 2nd day of the withdrawal of the CV catheter according to a predefined protocol. Diagnosed or strongly suspected CLABSI and central venous catheter related deep venous thrombosis (DVT) will be followed up for definite outcome to determine the frequency of severe adverse events attributed to CLABSI until the patient discharges from the hospital. Neurological outcome will be documented according to several disability assessment scales throughout the SVPE until discharge and up to four weeks from the enrollment of the GBS patients. In addition, the safety of the SVPE in GBS patients will be compared with the background complication risk by determining the frequency of complications in non-GBS patients treated with a CV catheter at the same intensive care unit (ICU) during the same period using the same protocol for surveillance as in SVPE-treated GBS patients.