The risk of developing endometrial cancer for post-menopausal women taking tamoxifen is well established as well as the incidence of endometrial thickening endometrial adhesions and polyps (17). There is no available data whether changes in the endometrium that may be induced by Tamoxifen further impairs the ability to conceive. Ultrasound assessments of the endometrium in patients treated with tamoxifen are limited and often inconclusive mainly due to sub-endometrial ultrasonographic findings that impair evaluation. The incidence of endometrial adhesions and polyps in premenopausal breast cancer patients treated with tamoxifen is unknown. However these abnormalities can interfere with the success of future conception.