In a press release, South San Francisco, California, and Basil, Switzerland on March 14, 2005, an interim analysis of a Phase III trial showed bevacizumab plus paclitaxel and carboplatin improved overall survival compared to chemotherapy alone as a first-line therapy for non-squamous, non-small cell lung cancer. These results were presented at the American Society of Clinical Oncology (ASCO) meeting, May 13-17, 2005. This was a randomized, controlled, multicenter trial that enrolled 878 patients who had not received previous chemotherapy for non-small cell lung cancer, and compared standard chemotherapy with paclitaxel and carboplatin with or without bevacizumab. The trial was sponsored by the National Cancer Institute (NCI), part of the National Institutes of Health, under a Cooperative Research and Development Agreement between NCI and Genentech, Inc., and conducted by the Eastern Cooperative Oncology Group (ECOG).