The British Thoracic Society (BTS/SIGN, 2012) and Global Initiative for Asthma (GINA, 2012) guidelines provide the background definitions for three broad categories of asthma control. They include controlled (no nocturnal wakening, infrequent short acting beta 2 agonist (SABA) use e.g. < 2 puffs/week, occasional mild symptoms e.g. with exercise and no exacerbations in last 3 months), partially controlled (nocturnal wakening < 3 nights/week, SABA use e.g. < 4 puffs/day, mild limitation in exercise tolerance due to asthma, and 2 or fewer mild exacerbations in the previous 3 months) or uncontrolled (nocturnal wakening 4-7 nights/week, SABA use e.g. > 5 puffs/day, limitation in exercise tolerance due to asthma and or significant asthma exacerbations requiring oral steroid, Emergency Department attendance or hospital admission in the previous 3 months). Children who present with partially controlled or uncontrolled asthma can be divided into difficult to treat asthma (DTA) and true severe therapy resistant asthma (STRA) after careful investigation (Hedlin et al., 2012). DTA occurs when asthma is uncontrolled but the impact of concomitant disorders and the basics of asthma care (inhaler technique and adherence) have not been adequately resolved.