The primary objective of this proposed three-year (January 01, 2018 to December 31,2020) project is to verify the effect of 'Joyful Sleep' intervention on young and middle-aged patients with insomnia in China and preliminarily explore the genetic level inflammation mechanism for the treatment of insomnia applied by it. Previous researches show that Mindfulness-Based Interventions may relieve insomnia, it is hypothesized that 'Joyful Sleep' will be an effective, feasible and affordable insomnia reduction program in China.