Significance and importance Although it is reasonably argued that propofol sedation can be administered safely by non-anesthetists, there is still the possibility of serious airway complications and cardiorespiratory depression.43 The administration of propofol should not be undertaken lightly and certainly not used for an indication that has not been subject to rigorous trial. Previous studies of propofol and headache have only examined the short- term impact of this intervention on pain scores. The study proposed here looks at the effect of this treatment on pain and quality of life over a longer period - 30 days.