To determine the ratio between HRQoL and patient outcomes and the health related costs, quality adjusted life years (QALYs) will be calculated. QALYs are a measure of the state of health of a person or group in which the benefits, in terms of length of life, are adjusted to reflect the quality of life. QALYs are calculated by estimating the years of life remaining for particular treatment and weighting each year with a quality of life score.54 Software Package for the Social Sciences (SPSS) will be used for data analysis.