Over the past 5 years, there have been 20 studies examining the effect of Gabapentin on postoperative pain (1 & 3-22). All but one of these studies (16) has found that Gabapentin demonstrated a significant reduction in the amount of postoperative opioid required (16-67%) and a simultaneous reduction in pain scores. There was no difference in side effect profile between the Gabapentin and the control groups in 11 studies(3-5,7,8,10,14-16,18,20), while one(18) found a higher incidence of nausea and urinary retention in the control groups, and two studies(11,13) found a higher incidence of nausea/vomiting in the Gabapentin group. The most common side effect of increased sedation was found in only 4 studies when doses greater than 900 mg per day were given (9,11-13). The daily dose of postoperative Gabapentin in the current protocol is 200 mg TID (600 mg/day) which we currently use in our clinical population with minimal side effect issues.