4. Must be in good health on the basis of physical examination, vital signs, medical history, safety laboratories, and the investigator's clinical judgment. Safety laboratory normal ranges will be those used by the reference clinical lab. Protocol-specific criteria for individual subjects are listed in criteria #6 -The clinical laboratory evaluations that will be graded as laboratory AEs and be considered for the Study or Individual Halting Rules are those which are included in the laboratory toxicity grading scales (Section 9.2.3). -Vital signs must be in normal ranges as per Sections 9.2.2 and 9.2.3. If a subject has elevated systolic or diastolic blood pressure, subject may rest for 10 minutes in a quiet room and then the blood pressure may be retaken once.