Genotyping, antimalarial drug concentration, haemoglobin and white blood cell count 100µL of blood will be collected on Whatman 3MM filter-paper using a capillary tube on day 0, 7, 14, 21, 28, 35, 42 and whenever reparasitaemia is detected. Filter-papers will be dried and then placed inside separate sealed plastic bags. Filter-papers and bags will be labelled with study number date and follow up day. The samples will be stored at -20˚C. Blood samples will be obtained at the same time that blood is taken for microscopy.