The patients will be observed for additional known signs and complications of acute pancreatitis such as persistent inflammation, shock, sepsis, electrolyte abnormalities, renal failure or other end organ damage. Any adverse reactions during the trial will be treated independent of the trial, and the attending physician will continue to manage the care of the patient at their discretion. Any serious adverse reactions will be documented clinically and reported to the CHKD or CNHS incident reporter systems, Eastern Virginia Medical School (EVMS) Institutional Review Board (IRB), CNHS IRB and CHKD Human Research Coordination (HRC) Committee .