All participants will provide written informed consent prior to screening or enrollment. Any adverse events associated with anti-helminthic medications will be managed by the appropriate clinic site, and if necessary, hospitalization. The costs of this care will be borne by the study. All clinical information including HIV status that is collected for the purposes of the study will be delinked from any client's identifier. This includes data collected in the clinic and in the laboratory. All data will be entered into a password protected computer with no links to identifiers. The code linking individual patient identifiers to a unique study ID will be kept securely locked in a separate location under control of the study principal investigator. All study files will be accessible only to researchers and will be stored in a locked office when not in use.