Why is this phase only 4 weeks? Exacerbations and infections can elevate CRP levels by 2 to 10 fold. The rate of normalization of CRP levels after these episodes is variable; complete normalization may not take place for several weeks after the resolution of the infective or exacerbation episode. To reduce the risk that the study participants will experience clinically apparent infections or exacerbations, we have made this phase of the study relatively short (4 weeks). The short treatment period will also reduce the effects of non or suboptimal compliance of treatment medications on CRP levels. We believe that 4 weeks of therapy will be sufficient to demonstrate the suppressive effects of Flovent and Advair, given the fact that in the pilot study, an effect of Flovent on CRP after only 2 weeks of therapy was observed.