Complete ophthalmic examination and Optical Coherence Tomography (OCT, Model 3000, Zeiss, Humphrey Systems) were performed immediately before each infliximab infusion, as well as 2 months after the last infusion. The main outcome measurements were best corrected visual acuity (BCVA) and macular thickness. The OCT-derived maximum height of DME was recorded as described previously in detail. The student t-test for paired data was used to compare logarithm of minimum angle of resolution (logMAR) transformed BCVA, as well as macular thickness between baseline and post-treatment.