5. Pre-transplant testing. To determine final eligibility for the study, subjects will undergo a series of tests/procedures. These include: CXR, electrocardiogram, endoscopy , ultrasound of the liver and gallbladder,transvenous liver biopsy, lymphopheresis, pulmonary function test, urinalysis, and blood testing to include CBC; chemistries; liver and kidney function tests; PT; PTT; AMA; viral studies and, for females, a pregnancy test. Subjects will also be evaluated by a dentist at Northwestern Memorial Hospital to rule out any potential sources of infection. All pre-transplant testing is routine medical testing done to verify diagnosis and to insure adequate organ function and absence of viral illnesses which would preclude a safe transplant course. Allogeneic donors will also need to undergo testing in order to determine eligibility to proceed. Testing for donors will include history and physical, electrocardiogram, CXR, urinalysis, CBC, chemistries, PT, PTT, viral studies and, for females, a pregnancy test.