Study Intervention Patients who are eligible to participate and who give informed consent will undergo a regimen of phlebotomy in the following manner. Starting after 60 days post-transplant, the patients will undergo a phlebotomy of 500 mL of whole blood monthly for a total of 12 treatments. There will be a determination of the complete blood count prior to each phlebotomy and if the hemoglobin level is less than 100 g/L, the phlebotomy will not be performed. Patients will not routinely receive crystalloid volume replacement following the phlebotomy. However, if a patient experiences syncope or pre-syncope, subsequent phlebotomies will be followed by the infusion of 500 mL of normal saline.