The primary efficacy outcomes were number of patients with severe pain, time to first rescue analgesia and postoperative morphine consumption. Severe pain was estimated as VAS≥7 during 30% or more time in first 48 hours after surgery. Time to first rescue analgesia was estimated as time from end of anesthesia to the time postoperatively when patient ask for analgesia or have VAS≥4. Injection morphine hydrochlorides 10mg subcutaneously was used as a rescue analgesic. NSAIDs (dexketoprofen 150mg per day) were prescribed routinely.