Blood sampling process For each blood sample, 1 ml of whole blood will be collected and used for the immediate quantification of glucose and lactate (Biosen C, EKF Diagnostics, UK). On samples where the additional 11 ml of blood is taken, the remaining blood will be transferred into tubes designed to collect blood plasma and serum. Both containers will then be centrifuged at 3000 x g for 15 minutes to obtain plasma and serum, which will be stored at -80 C° for later analysis of insulin (Invitron, UK), triglycerides (Randox Labs, UK), Apoliopoprotein-B48 (Oxford Biosystems, UK), Apolipoprotein-B-100 (Oxford Biosystems, UK), non-esterified fatty acids (Randox Labs, UK), TNF-α (Sigma Aldrich), GLP-1 (Oxford Biosystems, UK), PYY (Sigma Aldrich, UK), Total Antioxidant capacity (Eagle Biosciences, UK), and Human Myeloperoxidase (Eagle Biosciences, UK).