Randomizing and un-blinding: All drugs are delivered blinded and randomized from the pharmacy. In occurrence of life threatening or other unacceptable side effects of the treatment, a patient can be un-blinded after decision from sponsor or investigator. The randomization list will be kept by secretary Malene Kronborg Have and MD Tina Dysgaard Jeppesen in Denmark. These two persons are available 24 hours a day and are not involved in the study otherwise.