This is a double-blinded randomized control trial of subjects with pelvic organ prolapse who, after counseling at their initial visit, opt for treatment with a vaginal pessary. Patients who have a Gellhorn or Ring with support pessary placed with then be randomized to one of two arms for application of a local vaginal cream: estrogen or placebo. The object of the study is to compare the incidence of vaginal discharge and vaginal erosion in each study arm. We will also compare subjective measures including quality of life and satisfaction with their treatment plan.