Any infection will be treated by antimicrobial agents accordingly. Choice of the antibiotics (oral or intravenous) will be based on the site of infection, specific organisms isolated and/or severity of the infection reflected in clinical and laboratory features of systemic inflammatory response (raised total white blood cell (WBC) count (>11,000/c mm of blood), C-reactive protein (>40 mg/L) or positive culture of pathogenic organisms) and choices are made after consultation of a microbiologist. Appropriate lower generations of antibiotics for predicted site specific infection will be administered first if necessary before considering subsequent higher generations until the culture sensitivity report is available.