Chest pain patients will be identified and consented in the ER waiting area following initial triage and exclusion of STEMI and within 1 hour of initial blood draw at presentation. For chest pain registry, coordinators will also invite NHCS inpatients to participate. The Clinical Coordinators, under the guidance of Study Team investigators, will be responsible to identify appropriate study candidates to join this study. They will assist the study team investigators to explain the purpose of the study and obtain informed consent for additional blood draws as well as a follow-up telephone/ medical records outcome survey. Patients will be invited to join a registry where details regarding their clinical findings, relevant investigations and clinical outcomes will be stored for possible future reference in a database. Additionally, patients will also be asked if a 6-minute ECG can be performed on them. The Clinical Coordinators will perform the 3 phlebotomy draws, which must occur within the following window periods after the presentation draw to be included in the study: