Conservative treatment: firstly, hydro-electrolyte and thyroid function were assessed, and corrected if abnormal. Maintain the blood glucose at the normal level. Patients proning to be diagnosed with sepsis were adminstered antibiotics empirically, and adjusted to more targeted antibiotics according to the ensuing result of blood culture and drug sensitive test. Patients were subject to fasting, gastrointestinal decompression via stomach and anal tube. Gastric residual volume (GRV) was assessed per diem. Pharmaceuticals impacting bowel movement were suspended as far as possible, such as opiate, anticholinergic drugs, and calcium channel blockers (CCB). Intravenous administration of proserine was considered if cecum diameter > 10 cm after the treatement described above and show no signs of ameliaration in 24 h.