A range of therapeutic agents exist for the treatment of type 2 diabetes. Metformin, a biguanide, is a commonly prescribed oral anti diabetic drug; American Diabetes Association (ADA)/European Association for the Study of Diabetes (EASD) guidelines recommend metformin as initial pharmacotherapy for type 2 diabetes, with an expected reduction in HbA1C of between 1.0% and 2.0%. In their recommendations, both the ADA and the International Diabetes Foundation support metformin as initial pharmacotherapy for type 2 diabetes.