The study will collect data for a period of 1,5 year. 300 critically ill children will be recruited. Approximately 20% of the PICU patients exhibit clinical deterioration events, and with a median (IQR) length of stay of 3 (2-7) days [8] and at least one event per day, we expect a minimum of 180 events of clinical deterioration in the yearly population. From previous studies with a similar event distribution [15,16] we expect our models to result in a sensitivity (and specificity) of at least 0.8, with an alpha error of 5% and a statistical power of 80%.