Research subjects will receive a fixed dose of the allogeneic breast tumor vaccine consisting of two irradiated allogeneic breast cancer cell lines transfected with the GM-CSF gene in a specifically timed sequence with a low dose of Cyclophosphamide and Trastuzumab. Patients will receive 300 mg/m2 of Cyclophosphamide on day -1, and the vaccine on day 0. Weekly Trastuzumab will be timed to coincide with Cyclophosphamide administration. Research subjects will receive three monthly vaccination cycles, with a fourth and final (boost) vaccination cycle three months from the third cycle.