6. Subject has symptomatic CNS metastases. Subjects with prior history of symptomatic CNS metastasis must have received treatment (i.e., stereotactic radiosurgery (SRS), whole brain radiotherapy (WBRT) or surgery) and be neurologically stable for at least 1 month, not requiring anti-seizure medications and off steroids for at least 14 days prior to leukapheresis and lymphodepletion. Subject who has asymptomatic CNS metastatic disease without associated edema, shift, requirement for steroids or anti-seizure medications are eligible. If such a subject receives SRS or WBRT, a minimum period of 2 weeks needs to lapse between the therapy and lymphodepletion. Patients with leptomeningeal disease or carcinomatous meningitis are NOT eligible.