Aim 1: All analyses will be intent-to-treat. To assess the success of randomization we will compare baseline characteristics between the 2 randomization groups using Chi-square tests for categorical data and Mann-Whitney U-tests or t-tests for continuous data. To determine the effect of anti-helminth treatment on disease progression markers, we will compare the time to eligibility for ART between the groups and the time to CD4 counts of less than 200 and 350 respectively using Cox regression analysis models. If current treatment guidelines for the initiation of ART change during the course of the study, the analysis plan would incorporate that change in ART eligibility criteria as a date dependent event. In addition, we will compare changes in measurements of mean CD4 count and log10 plasma HIV-1 RNA in the two study arms using linear mixed effects models or linear regression censoring values after initiation of ART.