8. Patient has adequate bone marrow and organ function as defined by the following laboratory values: o Absolute neutrophil count (ANC) >/= 1.0 x 10^9/L; Platelets>/= 100 x 10^9/L ; Hemoglobin >/= 9.0 g/dL ; Serum creatinine </= 1.5 x upper limit of normal (ULN) ; Total serum bilirubin </= 1.5 x ULN o Alanine aminotransferase (AST) and aspartate aminotransferase (ALT) </= 2.5 x ULN ; Fasting plasma glucose (FPG) </= 140 mg/dL or </= 7.8 mmol/L