Study design: The study is a prospective, randomized, open-label, blinded end-point trial that will enroll patients with multivessel, stable coronary artery disease undergoing ischemia-related PCI (evaluated by stress test and/or FFR during coronary catheterization), and requiring staged PCI. Patients that experience an acute coronary syndrome in multivessel coronary artery disease, and that need to complete the revascularization in the non-culprit vessel, may be considered stabilized after one month from the culprit vessel PCI, and therefore may be enrolled. After the procedure the patients should be treated according to local routines. Randomization will be blocked within each study site, in order to get an even balance of patients randomized to either drug within each recruiting center.