All enrolled participants will have scheduled study visits every third month for 24 months (enrollment, months 3, 6, 9, 12, 15, 18, 21 and 24) at the clinic from which they were enrolled. At each follow up visit, a standardized questionnaire designed to assess any change in socio-demographic variables or clinical history will be performed. A physical examination will also be performed at each visit. Blood will be collected at enrollment, months 6, 12, 18 and 24 for measurement of full blood count with differential and CD4 count. Measurement of HIV-1 RNA will be collected at enrollment, the 12 month visit and the 24 month visit. All blood will be separated into plasma and PBMC's (peripheral blood mononuclear cells) and stored for future studies. Any future study utilizing stored specimens will obtain approval from both the Kenya Medical Research Institute and the University of Washington Ethical Review Boards. All participants will provide a single stool sample at the final 24 month follow up visit to determine helminth infection status at that time.