Throughout the procedure, haemodynamic status including blood pressure, heart rate, any cardiac arrhythmia, oxygen (%) saturation in peripheral blood, fluid intake and output will be monitored daily as per standard practice in all ICU patients. Blood coagulability will be monitored with prothrombin time (PT) and bleeding time (BT) every alternate day. Autonomic parameters will be documented daily as per the presence of high or low blood pressure, increased or decreased pulse rate, orthostatic hypotension, cardiac arrhythmia, bladder and gastrointestinal dysfunction, pupillary abnormality, unusual sweating or hyper salivation.