We propose to study 20, non-smoking, asthmatic adults. Subjects will be recruited from outpatient asthma clinics in Edmonton. All subjects will meet GINA criteria for mild persistent to moderate persistent asthma. Following informed consent we will obtain blood, induced sputum and urine samples after an overnight fast and free of any caffeine for at least 24 hours. We will also obtain routine demographic information including age, sex, and usual asthma medication usage. We will obtain health related quality of life status using generic (15D) and disease specific (Asthma Quality of Life) questionnaires. Subjects will be instructed regarding use of peak flow meters and the typical symptoms associated with loss of asthma control. They will be instructed regarding accessing a dedicated asthma website that incorporates the above questions (Visit 1). There is also a place for subjects to enter twice daily peak flow measurements. The website is password protected and each subject can access only their own individualized data entry pages. A research coordinator is able to access any subject data again using a unique password. We will use this internet-based program to monitor daily PEF and daily asthma symptoms. Patients will be instructed to access the website daily and will reassessed at 2 weeks. Subjects will then be instructed to continue with their usual asthma management and to log on to the asthma website daily to record symptoms and twice daily peak flows. Only subjects meeting criteria for well controlled asthma (GOAL criteria) along with objective compliance with study protocols over 2 weeks will then be enrolled in the next phase of the study.