4. History of another primary malignancy except for: 1) Malignancy treated with curative intent and with no known active disease >/=5 years before the first dose of study drug and of low potential risk for recurrence. 2) Adequately treated non-melanoma skin cancer or lentigo maligna without evidence of disease. 3) Adequately treated carcinoma in situ without evidence of disease (eg, superficial bladder cancer).