A total of maximum 24 mL venous blood will be drawn from each included patient. P-(plasma) glucose (<1 ml, will be analyzed in the ambulance). An additional 5 tubes of venous blood will be taken: 1. P-lactate (Sodium fluoride tube, 4 ml), 2. P-SuPAR (EDTA tube, 4 ml), 3. P-HBP (EDTA tube, 6 ml- in the pilot study 4 ml), 4. EDTA tube 6 ml: whole blood for cytokines (caspase-1 generated interleukins: IL-1β, IL-18, IL-37), glucose metabolites and downstream regulators of immunometabolic processes (pyruvate, lactate, HIF, mTOR, etc) and 5. PAXgene tube 2,5 ml: whole blood for priming step of the inflammasome mRNA levels of pro-IL and NLRP3.