One hour before surgery, patients will be premedicated orally with diazepam 5 mg and pantoprazole 40 mg. For induction into anesthesia short-acting intravenous anaesthetic agent propofol will be used in doses 1 - 2 mg/kg of body weight (BW) administered as a slow bolus doses (20 - 30 s), while remifentanyl (Ultiva, GlaxoSmithKline, GSK Export VB) as a short-acting synthetic μ-opioid agonist will be used in initial loading dose of 1 - 1.5 µg/kg of BW administered in 30 to 60 s period.To facilitate endotracheal intubation a muscle relaxant vecuronium bromide will be administered intravenously.