Recognition of the increased need for effective neural interfaces for prosthetic limbs has been evidenced by an expanding number of efforts in this sphere over the past decade. Initial efforts to provide high resolution control of distal prostheses were focused primarily on direct and indirect brain interfaces, either through placement of electroencephalographic scalp sensors or implantable parenchymal electrodes, respectively. However, such endeavors have been plagued by poor resolution, inconsistencies in signal acquisition and progressive foreign body reactions leading to impulse degradation over time.