Some literature data and the results of our in vitro studies strenghten the idea that the role of salivary alpha-amylase in starch digestion has been under-rated and that this enzyme can an important role in this process. As a result, its inhibition could constitute an opportunity to reduce the glycemic response elicited by starch-rich foods. The main goal of this study is to verify whether inhibition of salivary alpha-amylase, upon the consumption of starchy foods, can have an impact on the postprandial glycemic response, and/or satiety.