In figure 1 schematic StO2 measurement line-drawing during UIRT is presented. The following parameters were obtained: basal StO2 (%): basal StO2 before cuff inflation (maximal thenar muscle StO2 was found by moving probe over thenar prominence); StO2 downslope during cuffing (∆downStO2)%/sec); StO2 upslope (∆upStO2)%/sec) after cuffing release; overshootStO2 (%): maximal StO2 after cuffing release. Inspectra measures content of hemoglobin in sample volume of underlining tissue - Tissue Haemoglobin Index (THI). Average of muscle THI before and at the end of cuff inflation was reported. These data were automatically obtained using the Inspectra Analysis Program V2.0 (Hutchinson Technology Inc., USA) running in MatLab 7.0 (MathWorks Inc., USA). Estimation of muscle oxygen consumption (mVO2Nirs) and muscle oxygen extraction ratio (mOER) were calculated using the following formulas: