Importance and relevance of the study: If the choice of imaging method significantly affects predictors of good outcome after thrombolytic therapy initial use of the superior method would lead to a benefit, which for the individual patient will correspond to less disability after a stroke. Study results can be implemented directly in clinical practice; thought it will be subject to an eventual need for revised allocation of resources even though the total number of scans will not be affected. Based on the study's registration of resource consumption, the health economic effects of the study can be estimated. Since stroke is a very common and serious disorder, relatively minor improvements in the prognosis may have noticeable effect on group or community level. Further, this study may close a long-standing and sometimes emotional scientific discussion, setting as an example that trials remain the only valid method of answering scientific questions. This set up with a research protocol complementing a quality project enables us to evaluate this issue.