TOTAL NUMBER OF HUMAN RESEARCH PARTICIPANTS PROPOSED FOR THIS STUDY. 48 pediatric subjects: 12 in each of the following developmental age groups: 6 months-1year, 1-6 years, 6-10 years, and 11-17 years. This number of participants will provide representative data for a pilot study investigating the most common age groups seen in the pediatric ICU in order to identify the age groups most likely to benefit from further study.