If any response suggests the subject is having trouble remaining smoke-free or if they have started smoking again, a study nurse will call to help get the subject back on track and not smoking. This smoking cessation counseling will include assessment of whether the subject is taking varenicline (Champix) in the prescribed dosage, whether they are experiencing any adverse effects, the number of cigarettes and time of day they are smoking, triggers for smoking, and assistance to develop coping mechanisms to reduce these triggers. If the subject is not experiencing any adverse effects they will be advised to continue taking varenicline (Champix). If they are still smoking, they will be advised to try not to increase the number of cigarettes smoked per day.