Background: Monitoring the patient safety and quality of nursing care is essential to identify patients at risk. Monitoring the nursing-related patient safety and quality indicators are important for high-quality nursing care. However, monitoring nursing-related patient safety and quality indicators through information system is a challenge. The nurses' to date workload is increasing. The comprehensive nursing-related patient safety and quality indicators information system should be used to make nurses work of collecting indicator data more efficiency and enhance patient care quality.