- Known heart disease or clinically significant abnormal electrocardiogram during screening as determined by the study MD; 10. Uncontrolled hypertension; 11. Presence of a metallic implant contraindicative to scanning at the 7T level; 11. Claustrophobia. 12. Consistent systolic blood pressure of >145mm Hg or diastolic blood pressure >90 mm Hg after three readings at time of screening; 13. Known renal impairment and End Stage Renal Disease (ESRD).