In order to assess the clinical relevance of the spectral-based model the investigators will compare its performance and overall accuracy with a model built using the most associated and clinically relevant variables (e.g. highest recorded value of neuron-specific enolase, somatosensory evoked potentials) to the primary outcome. To develop a clinical-based predictive model, each of the clinical variables will undergo univariate analysis to evaluate its association with in-hospital FNP.