Statistical analysis: the statistical analysis will be carried out by intention to treat as per protocol. Categorical variables will be shown as frequencies and proportions. The continuous variables will be analyzed with the Z of Kolmogorov-Smirnov to determine their distribution. Those with normal distribution will be shown with mean and standard deviation, while those with abnormal distribution will be presented with median and interquartile range. To compare the 2 groups Chi square for the categorical variables will be used. If it is shown that the AKI frequency is reduced, the relative risk reduction will be calculated. The numerical variables with normal distribution will be analyzed with one-way ANOVA and post hoc analysis with Bonferroni test, whereas in the case of variables with abnormal distribution, they will be analyzed with the Kruskal-Wallis test. A p less than 0.05 will be considered significant.