The stage 2 part of the current study will be performed in patients undergoing cardiotoxic chemotherapy (N=70), randomized for comparing a surveillance strategy using machine learning approach (group A, N=35) from conventional surveillance based on conventional echocardiographic parameter as LVEF (group B, N=35). Patients coming to the echo lab for echo surveillance of LV function will be randomized to optimized automated algorithm or receive standard LVEF alone.