The researchers were not able to assess the criterion for DSM-IV melancholic depression that mood be subjectively different from guilt in the assessment because this is not measured by the HAMD-17 or MADRS. However, any participant meeting this subsample definitions would also meet the full DSM-IV-TR criteria. One grouping variable for melancholic depression (coded as 1 "present" and 0 "not present") will be created and all participants will be assigned a value.