- Guided Bone regeneration (GBR) procedure using Ti-mesh: (standard of care excluding clinical measurements) The following steps will be performed following standard of care procedures: local anesthesia, muco-periosteal incision, full thickness flap reflection, de-cortication of the alveolar ridge, bone harvesting using bone scrapers, tenting screw placement, clinical measurements, DBBM graft material placement, the placement and stabilization of the titanium mesh according to manufacturer's instructions, sutures.