Hematology：Absolute neutrophil count greater than 1000/mm(3) without the support of filgrastim，WBC greater than or equal to 3000/mm(3)，lymphocyte count greater than or equal to 800/mm(3)，Platelet count greater than or equal to 100,000/mm(3)，Hemoglobin > 9.0 g/dl Chemistry：Serum ALT/AST less than or equal to 2.5 times the upper limit of normal，Serum Creatinine less than or equal to 1.6 mg/dl，Total bilirubin less than or equal to 1.5 mg/dl, except in patients with Gilbert s Syndrome who must have a total bilirubin less than 3.0 mg/dl.