Study Design Five male pedophiles entered a prospective, repeated measures, nonrandomized, masked study. All subjects and investigators, except the Principal Investigator (PI), Project Director, and Study Coordinator, were masked. The PI administered the drug or placebo; the PI and Project Director designed the study and were cognizant of the dosing schedule; and the Coordinator was responsible for supply of study drug. However, the PI, Project Director, and Coordinator were not involved in direct data collection or evaluation of the subjects. Each subject served as his own control. Subjects received weekly cognitive-behavioral psychotherapy for 24 months and LA depot injection, 7.5 mg at baseline and 22.5 mg at months 1, 4, 7, and 10. Flutamide (250 mg TID for 14 days) was only administered with the first injection.