The treating clinician and the study coordinator will manage the clinical care and study related procedures. Complete metabolic panel (CMP) and liver function tests (LFT) will be obtained once a year as Standard of Care, or more often if deemed necessary by the treating clinician. Complete blood counts (CBC) with differential and CD19+ labs will be collected at Baseline, month 1 and every 3 months from baseline to monitor B cell recovery. The examining clinicians and primary study coordinator will be blinded to the CD19 lab results.