Non-childbearing potential is defined by at least one of the following criteria: a.>2 years spontaneous amenorrhea (not attributable to environmental or pathological causes, eg, anorexia or excessive exercise) with follicle-stimulating hormone (FSH) in post-menopausal range at the Screening Visit (A naturally menopausal woman on a stable dose of hormone replacement medication does not require an FSH at the Screening Visit.), or b.at least 3 months post-surgical bilateral oophorectomy or tubal ligation, or c.hysterectomy (must be greater than 5 years post-hysterectomy, if due to cancer).