On the other hand, Fenton et al. (2002) investigated augmentation of neuroleptics with 3 g/day of EPA on symptoms and cognition in patients with schizophrenia or schizoaffective disorder and reported a negative finding. The patients in Fenton et al.s' study had, however, been ill for two decades and had substantial symptoms, despite treatment with newer neuroleptics, including clozapine. The patients described as benefiting from EPA in the other studies were younger and had a shorter duration of illness.