Esophagectomy was considered as the criterion standard for treatment of patients with early EAC. However, it is associated with significant morbidity and mortality, even in experienced surgical hands and high-volume surgical centers. EMR has been used increasingly to replace surgery as a curative treatment modality for early EAC in patients with BE (12, 13). It allows effective local treatment of early cancer, histological analysis of all resected specimens and thus confirmation of diagnosis and complete resection of the lesion. Ablative therapies in BE patients have provided promising results as well (18, 19).