- Subject has a medical condition that requires chronic systemic steroid therapy or requires any other form of immunosuppressive medication. However, subjects using physiologic replacement doses of hydrocortisone, or its equivalent, will be considered eligible for this study: up to 20 mg of hydrocortisone (or 5 mg of prednisone) in the morning and 10 mg of hydrocortisone (or 2.5 mg of prednisone) in the evening. Topical, intraocular, and intranasal steroids are allowed.