We will collect information including such items as psychiatric diagnoses and symptoms, biomarkers of liver and other organ damage, quantitative alcohol use history, other substance use, and family history of alcoholism. Using this information, investigators will be able to clinically manage any disorders in need of clinical attention, and determine whether subjects are eligible for any NIH research studies (for which this protocol serves as the screening platform) based on results of screening evaluations and the participants interest in receiving treatment for AUD. We will also acquire whole genome data, with which investigators will be able to examine the relationship between genetic variation and alcohol-related phenotypes.