METHODS: Randomized single-blind single-centre controlled clinical trial with a 2x2 cross-over design. A sample of 124 patients attending to the outpatient gastroenterology unit at Clínica Fundadores in Bogotá city, who meet the inclusion criteria and have no exclusion criteria will be selected to participate. Included patients will be randomized to raise the head of bed with standard 20 cm-height wooden blocks or to sleep without bed inclination during the first 6 week period. After a 2 week washout period, allocation will be crossed and participants will be followed again during a second 6 week period. During the trial, every patient will receive standard pharmacological treatment with a proton pump inhibitor and/or sodium alginate. After allocation concealment, the researchers in charge of statistical analysis and reporting results will be blinded for the non pharmacological intervention under study. Primary outcome is a significant symptom change according to Reflux Disease Questionnaire (RDQ) validated form. Secondary outcomes include impact on quality of life according to Short Form 36 (SF-36) validated questionnaire, patient preference and adverse events of non-pharmacological intervention. Statistical analysis will be carried out with the Statistical Package for Social Sciences (SPSS) 16.0 for Windows. Differences with a p<0,05 will be accepted as statistically significant.