- Hepatic function: total bilirubin < 1 upper limit of normal (UNL); ASAT (SGOT) and ALAT (SGPT) < 2.5 UNL; alkaline phosphatase < 5 UNL. Patients with ASAT (SGOT) and ALAT (SGPT) > 1.5 UNL and alkaline phosphatase > 2.5 UNL are not eligible.