The objective of this study is to evaluate the efficacy of the 4 tablets (2 capsules containing metronidazole, bismuth, and tetracycline) plus amoxicillin and esomeprazole) given twice a day for 10 days in the eradication of H. pylori. The primary end point is H. pylori eradication rate on ITT and PP analysis. Secondary endpoints include: (1) tolerability, (2) adverse events of the drug regimen, (3) and cost.