Phase I patients only: All of the six injections of LOAd703 will be done at BCM/BSLMC. The patient will stay at BSLMC over night for evaluation after the first two doses of LOAd703. As tolerated, the patient may be allowed to leave the hospital as soon as 4 hours after LOAd703 injection. Simultaneously to the LOAd703 treatments, and after the last LOAd703 injection, patients will continue to receive standard of care treatment.