This is a single institution, prospective pilot study to evaluate the safety and feasibility of MR guided high intensity focused ultrasound (HIFU) treatment for cancer of the neck in 10 patients. The procedure will consist of a planning MRI scan and a treatment session where real time MRI thermometry is used in conjunction with a focused beam to produce hyperthermia (55-90 degrees celsius for 20-30 seconds) within a pre-selected target lesion. All patients will be assessed by a physician investigator and clinical research assistant (CRA) on the day of treatment (day 0) and days 1, 7, 14, 30 and 90 post MR guided HIFU. In addition, at each visit including the treatment date, a Pain and Analgesics Form and an Anticipated Adverse Effects Screening Assessment will be completed by the CRA and physician with the patient. If specific adverse effects are identified, then the National Cancer Institute Common Toxicity Criteria (NCI CTCAE v4.03) will be used to assign a grade/score to the severity of the effect. All patients will undergo a follow-up MRI on day 14 and begin standard palliative radiotherapy/chemotherapy beginning no sooner than day 14 after the HIFU treatment.