Patient data will be kept confidential throughout the study. All electronic study data entry, storage and analysis will be done according to institutional data security policy, using password protected data in secure systems. The patient data collected will be de-identified and the key kept securely separated with access limited to principal investigator and co-investigators. A study-related identification number given to each patient will be used on the case report form. Research members will enter the de-identified data into the REDCap™ (Research Electronic Data Capture) tool hosted on a secure server at Singapore General Hospital. The hardcopy of the research data will be securely stored within the department. The softcopy of research data will be saved in a password-protected file and will be stored in institution approved login-protected system and encrypted hard-drive. Only study members will have access to the data.