If participant is enrolled in Phase 1, the dose of PF-04518600 participant receives will depend on when participant joins this study. Up to three (3) dose levels of PF-04518600 will be tested. About 3-6 participants will be enrolled at each dose level. The first group of participants will receive the lowest dose level of PF-04518600. The next group will receive a higher dose than the group before it, if no intolerable side effects were seen.