You will take bosutinib by mouth at about the same time each day with food. You will also take axitinib by mouth 2 times each day, about 12 hours apart, with or without food. You will switch which drug you are taking every 3 months. Some participants may start with axitinib and then switch to bosutinib. This means that for 3 months you will take either bosutinib or axitinib alone and at the end of 3 months, you will switch to the other drug for 3 months. This will continue every 3 months while you are on study. The study doctor will discuss with you which dosing schedule you will follow.