Currently, there is data that shows the benefit of post-conditioning in reducing reperfusion injury in animal models only. However the use of post-conditioning in humans to reduce reperfusion injury has not been well investigated.Given that endothelial dysfunction is a significant component of reperfusion injury, we propose to examine the effects of post-conditioning on a reperfusion injury by using BART. This study will act as a pilot by which we can compare the results of Post-conditioning to preconditioning to reduce the reperfusion injury with BART in a human reperfusion injury model. The clinical relevance of this study is paramount. If it can be shown that post-conditioning attenuates reperfusion injury in humans, as assessed by BART a larger scale trial to assess post-conditioning on prevention of ischemia reperfusion injury in humans will be necessary. Furthermore, this allows for a possible therapeutic application in the clinical setting, such as potentially providing post-conditioning measures to patients undergoing percutaneous coronary intervention for abruptly occluded coronary arteries. Attenuation of reperfusion injury may further reduce the associated morbidity and mortality of acute coronary ischemic events.