• Benefits: This study has been designed to address several areas of major public health significance for HIV-1 infected individuals in resource poor settings. If we are able to show that treatment of helminth co-infection in HIV-1 infected individual's delays immunosuppression, millions of HIV infected individuals in resource poor settings may benefit. Participants randomized to the intensive intervention arm will benefit from free treatment and examination given to them. All participants will benefit from intensive clinical and laboratory monitoring.