Because the prevalence of smoking among people with diabetes remains elevated (15), decreasing the exposure to tobacco products is a public health imperative also for subjects with diabetes. Moreover, the most recent US Clinical Guidelines for Treatment of Tobacco Dependence (2008) list diabetes, along with other comorbid medical conditions, as a target group for smoking cessation treatment, due to the increased health risks associated with this disease and smoking (16). It must be also noted that along all known modifiable cardiovascular risk factor (e.g. raised glycemic levels, elevated cholesterol levels, high Body Mass Index) smoking appears to be the most relevant for the reduction of morbidity and mortality in this patient population. Risk management parameters of CVD that include smoking cessation may reduce morbidity and mortality more than tightening glycemic control (17,18).