Suicide is a major health problem that causes annually a million death worldwild. Loneliness is known to be associated with suicidal ideation in minors and to be related with suicidal risk in elerly people. However little is known about this association in a middle-aged population. Loneliness is a modifiable factor with suitable psychotherapeutic measures, it is essential to improve the scientific and medical knowledge about the link between this feeling and suicide risk in a population of depressed patients in middle age.