Once signed the informed consent (CI) the patient will receive an initial program of intensive RR (hospital-based program standard according to usual practice) participate in this phase all the patients in the study and will receive equal treatment. This program will be taught in groups of 5 patients (approx) and will last a total of 8 weeks. Patients will have to go to the hospital 3 hours/d 3 days per week where respiratory rehabilitation program will be intensive.