The project aims to characterize an association between PCa aggressiveness and the composition of pelvic adipose tissue. Adipose tissue samples from patients with either low risk (n=100) or aggressive (n=100) PCa will be analyzed for 1/ the lipid profile (fatty acid composition and phospholipids proportions), 2/ expression of adipokines, and 3/ persistent organic pollutants with hormone-like activity. The analysis will take into account known factors of aggressiveness, including obesity, MetS components, ethno-geographic origin, and positive family history of the disease.