The cytokine analysis and VEGF measurements will be performed using Cytokine 29 Plex Kit Premixed Beads, HCYTO-60K-PMX29 (Linco Research, St. Charles, MO, USA). This kit measures various markers and proteins of the immune system to determine the degree of inflammation. Cytokines measured with the kit include: Human IL-1, Human IL-2, Human IL-1ra, Human IL-4, Human IL-5, Human EGF, Human IL-6, Human IL-7, Human TGF,_Human Fractalkine, Human IL-8, Human IL-10, Human IL-12p70, Human IL-13, Human IL-15, Human IL-17, Human IL-1, Human IFNgamma, Human G-CSF, Human GM-CSF, Human TNF, Human Eotaxin, Human MCP-1, Human sCD40L, Human IL-12p40, Human MIP-1, Human MIP-1beta, Human IP-10, and Human VEGF.