- The subject's corrected QT interval (QTc) (Bazett's or Fridericia's correction) is >450 ms as read on the printout of the ECG produced by the ECG equipment and evaluated by the investigator at the Screening Visit and at the Safety Baseline Visit. An out-of-range or abnormal ECG may be repeated. In total, 3 ECGs should be recorded consecutively and the investigator must evaluate the triplicate ECG. If the subject's QTc is >450 ms on at least 2 ECGs, the subject must be excluded.