The primary objective in Stage 2 is to determine progression free survival post-allogeneic transplant, in terms of time to treatment failure and survival. Stage 1 will include both prognostic subgroups CR and not in complete remission (NCR). In Stage 2, different monitoring rules will be used in CR and NCR subgroups to reflect their very different historical failure rates. Additionally, all patients treated at the dose selected in Stage 1 will be counted as members of the Stage 2 sample.