GERD symptoms are associated with bodily pain, impaired social, emotional and physical functioning which has a profound impact on daily living. Much research has been done to evaluate the true burden of GERD on our society. For instance, 40% of patients with nighttime symptoms of GERD reported that such symptoms affected their ability to function the next day. Furthermore, 27% of these patients reported that their own night-time symptoms affected their spouses ability to sleep (10). Clearly, this data indicates a huge number of Americans who report the effects of heartburn on personal and spousal quality of life. GERD symptoms need to be addressed effectively as successful treatment for GERD results in improvements in health related quality of life (11, 12). In the treatment of GERD, the goal should be complete symptom resolution as this has been shown to be associated with a clinically significant improvement in health related quality of life (HRQL) (13).