All investigations were carried out by SRL Ranbaxy Laboratories (www.srlranbaxy.com), Mumbai, which is accredited by the College of American Pathologist (CAP) and approved by NABL (National Accreditation Board for Testing and Calibration Laboratories, Department of Science and Technology, India). The plasma glucose (Hexokinase method), serum creatinine (Jafees Reaction), serum blood urea nitrogen (BUN) (Urease-GLDH method) LFT and serum lactate were estimated on DADE RXL (Dade Behring Ltd, USA2007). Serum cholesterol, serum triglyceride, serum HDL cholesterol were measured by enzymatic method (Randox Imola, Randox Lab., UK, 2007). The A1C was estimated by HPLC method (Bio-Rad Variant II, Bio-Rad Labs, USA, 2007). Microalbuminuria and Albumin/Creatinine ratio were estimated from fasting spot urine sample by Immunoturbidimetry (Randox Imola). Serum Insulin and C-Peptide were estimated by Chemiluminescence technique (Advia Centaur, Bayer Health Care, USA, 2003).