Adult men and women participating in or referred to the HIV Care and Treatment Clinics at each of the included sites will be offered screening for eligibility. HIV-1 seropositive individuals with a documented CD4 count greater than 350 cells/mm3 will be considered potentially eligible. Those who agree to participate, are willing and able to provide informed consent, are WHO stage I or II based on clinical exam and history, are 18 years of age or older, have not been treated with worm medication in the previous 4 months and who are not pregnant (based on urine beta-HCG testing if female) will be offered to participate in this trial. Pregnancy testing will be performed at each study visit (every three months) for all premenopausal women. Women who become pregnant during the course of the study will continue to be followed but will not receive any further study medication during pregnancy if they had been randomized to study arm A.