- All patients must have undergone hysterectomy. Bilateral salpingooophorectomy is strongly encouraged but not mandatory. Pelvic and para-aortic lymphadenectomy are optional, but strongly encouraged. Peritoneal washing are optional. If either a bilateral salpingo-oophorectomy or nodal dissection was not performed, post-operative pre-treatment CT/MRI is required. All patients will be staged according to the FIGO 2009 staging system and with endometrial carcinoma (endometrioid types) confined to the corpus uteri or with endocervical glandular involvement. Patients with Stage II endometrial carcinoma with cervical stromal invasion. Patients with serous or clear cell histology (with or without other high-intermediate risk factors) are eligible if disease is uterine confined. Adequate bone marrow, renal, hepatic and neurologic function.