The protocol is designed as a cross-sectional observational study. Participants will initially undergo an informed consent process and a core phenotyping evaluation, which includes a clinical evaluation from a Licensed Independent Practitioner and questionnaires. Following the core evaluation, participants may undergo selected scientific measurements for phenotyping purposes. Phenotyping measurements can occur over the course of several months. On completion of the phenotyping measurements, participants will be discharged from the protocol. After completion, past participants may be contacted to undergo re-evaluation as appropriate.