By increasing endogenous GLP-1 levels, vildagliptin also enhances the sensitivity of alpha cells to glucose, resulting in more glucose-appropriate glucagon secretion.
Suurendades endogeense GLP- 1 sisaldust, suurendab vildagliptiin ka alfarakkude tundlikkust glükoosi suhtes, mille tulemuseks on glükoosile sobivam glükagooni sekretsioon.