No recommendations can currently be made regarding adjustment of amprenavir dose when amprenavir is co-administered with methadone due to the inherent low reliability of non- matched historical controls.
Ühildamata kontrollgrupi vähese usaldusväärsuse tõttu ei saa anda soovitusi amprenaviiri annuse korrigeerimiseks selle kasutamisel koos metadooniga.