Patients with a treatment history of immunosuppressant medications, including cyclophosphamide and mitoxantrone, may experience prolonged immunosuppression and therefore may be at increased risk for PML.
Kui patsient on saanud immunosupressante (sh tsüklofosfamiidi ja mitoksantrooni), võib immuunsus olla pärsitud pikemaajaliselt, millega kaasneb PML tekke oht.