In a carcinogenicity study, male rats developed Leydig cell hyperplasia and adenomas, explained by the prolactin-inhibiting effect of pramipexole.
Isasrottidel kantserogeensuse uuringus arenenud Leydigi rakkude hüperplaasia ja adenoomid on seletatavad pramipeksooli prolaktiini- inhibeeriva toimega.