A few patients who have experienced hypoglycaemic reactions after transfer from animal source insulin have reported that early warning symptoms of hypoglycaemia were less pronounced or different from those experienced with their previous insulin.
On kirjeldatud üksikuid juhtumeid, kus loomse päritoluga insuliinilt humaaninsuliinile üleminekul väljendusid hüpoglükeemia esmased hoiatavad sümptomid nõrgemini või varasemast erinevalt.