Sildenafil is a potent and selective inhibitor of cGMP specific phosphodiesterase type 5 (PDE5) in the corpus cavernosum, where PDE5 is responsible for degradation of cGMP.
Sildenafiil on cGMP spetsiifilise 5. tüübi fosfodiesteraasi (PDE5) tugevatoimeline ja spetsiifiline inhibiitor.