In the same patients, these reactions have been avoided when the ACE inhibitors were temporarily withheld, but they reappeared upon inadvertent rechallenge.
Nendel patsientidel hoiti taolise reaktsiooni esilekerkimine mõneajalise AKE inhibiitori kasutamise katkestamisega ära, kuid see kerkis taas esile mõlema ravimeetodi uuesti kombineerimisel.