The following covariates were statistically significantly associated with a decreased risk of developing diarrhea: increasing cumulative capecitabine dose (0.1*kg) and increasing relative dose intensity in the first six weeks.
13 kõhulahtisuse tekkeriski vähenemisega: kapetsitabiini kumulatiivse annuse (0, 1* kg) suurendamine ja suhtelise annusetugevuse suurendamine esimesel kuuel nädalal.