Rifampicin increased the clearance of sirolimus by approximately 5.5-fold and decreased AUC and Cmax by approximately 82% and 71%, respectively.
Rifampitsiin suurendas siroliimuse kliirensit ligikaudu 5, 5 korda ning vähendas AUC ja Cmax vastavalt ligikaudu 82% ning 71%.