In healthy volunteers and patients, bivalirudin exhibits dose- and concentration dependent anticoagulant activity as evidenced as prolongation of the ACT, aPTT, PT, INR and TT.
Tervetel vabatahtlikel ja patsientidel on bivalirudiinil leitud annusest ja kontsentratsioonist sõltuv antikoagulantne toime, mida tõestavad ACT, aPTT, PT, INR ja TT pikenemine.