Both clomipramine and desmethylclomipramine contribute to the effects of Clomicalm: clomipramine is a potent and selective 5-HT reuptake inhibitor while desmethylclomipramine is a potent and selective noradrenaline reuptake inhibitor.
Nii klomipramiin kui desmetüülklomipramiin osalevad Clomicalmi toimes: klomipramiin on tugev selektiivne 5- HT tagasihaarde inhibiitor, samal ajal kui desmetüülklomipramiin on tugev selektiivne noradrenaliini tagasihaarde inhibiitor.