Epidemiological evidence regarding the risk of teratogenicity following exposure to ACE inhibitors during the first trimester of pregnancy has not been conclusive; however a small increase in risk cannot be excluded.
Epidemioloogilised andmed ei võimalda üheselt määrata riski teratogeensuse tekkeks AKE inhibiitorite kasutamisel raseduse esimesel trimestril, sellegipoolest ei saa ka välistada selle riski vähest suurenemist.