In phase III studies, 85% of the patients had a creatinine clearance between 30 and 70 ml/ min and 6% below 30 ml/ min at inclusion, and the mean creatinine clearance was about 50 ml/ min.
III faasi uuringutes oli uuringusse kaasamise hetkel 85% - l patsientidest kreatiniini kliirens 30 kuni 70 ml/ min vahel ja 6% - l alla 30 ml/ min, ja keskmine kreatiniini kliirens oli 50 ml/ min.