These include inhibiting the release of proinflammatory cytokines such as IL-4, IL-6, IL-8, and IL-13 from human mast cells/ basophils, as well as inhibition of the expression of the adhesion molecule P-selectin on endothelial cells.
Desloratadiin inhibeerib proinflammatoorsete tsütokiinide IL- 4, IL- 6, IL- 8 ja IL- 13 vabanemist inimese nuumrakust/ basofiilist ning inhibeerib adhesioonimolekul P- selektiini ekspressiooni endoteeli rakkudes.