Toxicologically significant effects were observed only at doses or exposures that were sufficiently in excess of the maximum human dose or exposure, indicating that these effects were limited or of no relevance to clinical use.
Ainult annustes, mis arvestatavalt ületavad maksimaalse ekspositsiooni inimesele ilmnesid toksikoloogiliselt olulised toimed, mis viitab nende toimete vähesele kuni ebaolulisele kliinilisele tähendusele.