The main measure of effectiveness was how far the patient could walk in six minutes (a way of measuring exercise capacity), but the study in class II disease also looked at the change in the resistance to blood flow in the lungs’ blood vessels (a marker of how narrow the blood vessels are).
Uuringutes hinnati efektiivsust peamiselt sellega, kui kaugele suutis patsient kuue minuti jooksul kõndida (koormustaluvuse hindamise viis), kuid II klassi haiguse uuringus vaadeldi ka kopsu veresoonte verevoolu resistentsuse muutumist (see näitab, kui ahenenud veresooned on).