But, so far, none of this has occurred, largely because nicotine is viewed as a highly addictive and toxic substance, with even smokers hesitating to try NRT or PNV for this reason. In fact, nicotine has been the primary target of anti-tobacco campaigns for more than three decades.
但是，目前所有这些都没有发生，这大部分是因为尼古丁被认为是一种高致瘾性有毒物质，因此，即使是烟民，在尝试NRT或PNV时也会犹豫不决。事实上，尼古丁成为反烟草运动的主要目标已有三十多年。