This variation of the genome is exceptionally common, present in 30% of individuals of European ancestry and more than 50% of those of Asian ancestry. In many such patients, doubling the dose of Plavix, and checking the platelet function with a point-of-care test to assure suppression, can override the lack of response.
这类基因变异非常普遍，30%欧洲血统和50%亚洲血统的患者是这类变异基因的携带者。 针对此类患者把波立维的给药剂量翻倍，并随时进行现场测试掌握血小板数量就能解决对药物不敏感的问题。 此外还有普拉格雷或替卡格雷等其他替代用药，这些药可以替代波立维防止支架堵塞。