As a result, after a few early successes with atypical single-gene disorders such as Huntington’s disease, progress has stalled. Common variants typically explain a small fraction of genetic risk.
事实上，大部分疾病都不是由单一基因引起的。结果，在非典型的单一基因失调疾病如亨廷顿氏症方面早期取得一些成功后，进展就停滞了。常见变异通常只能解释一小部分遗传风险。