Kimura’s theory was simple and elegant, but the classification of mutations into the distinct classes – beneficial, neutral, or harmful – seemed too simple to me. My own work showed that borderline mutations, those with very small positive or negative effects, could be very important in driving evolutionary changes.
木村的理论简单而优雅，但将突变分为有益、中性和有害的不同类别在我看来似乎太简单了。我本人的研究表明具有微小正面或负面影响的边缘突变可能在推动进化改变时意义重大。近乎中性的分子进化论正是以这种假设为基础的。