Treating women carrying BRCA1 or BRCA2 mutations with PARP inhibitors to kill cancer cells before they grow into tumors is a new and hopeful concept in cancer prevention. However, the usefulness of this treatment relies on the fact that PARP1 inhibitors are completely non-toxic to humans.
在癌细胞转变为肿瘤之前，用RARP抑制剂治疗那些携带BRCA1或BRCA2变异体的妇女是防癌方面一个全新的、大有前途的理念。然而，这种治疗法是否能够被使用还取决于PARP1抑制剂是否对人体完全无害。PARP抑制剂作为预防治疗之用还需要更长的时间的验证，因为治疗手段不会在短期时间内被证明有效。