The use of aspirin in young children is contraindicated, owing to the risk of Reye’s syndrome, a rare but serious complication. Paracetamol also remains the preferred drug to relieve pain or fever in children or adults with asthma, because aspirin or other non-steroidal anti-inflammatory drugs may provoke attacks of asthma in susceptible people with this condition.
由于会感染雷氏综合征的危险，这是一种罕见但却非常严重的并发症。禁止在年幼的孩子身上使用阿斯匹林。扑热息痛依然是为感染哮喘的儿童或成人解热或镇痛的首选药物，因为阿斯匹林或其他不含类固醇的消炎药可能会使存在该症状的易感人群反复感染哮喘。