Because the overwhelming majority of medical and pharmaceutical research is directed toward products that affect people in affluent countries, it targets only part of the global burden of disease. Some government- and foundation-funded research addresses diseases that primarily affect poor people, but these efforts are not systematic and do not use the incentives that work well to drive pharmaceutical innovation elsewhere.
由于绝大多数医疗和制药研究以影响丰裕国家人民的产品为目标，因此它们只能解决全球疾病负担的一部分。一些政府和基金会出资的研究以主要影响穷人的疾病为目标，但这些研究不系统，也缺少其他情况下效果显著的制药创新激励。