Our metabolisms started to malfunction when humans began consuming fat and carbohydrates at the same meal. The liver mitochondria could not keep up with the energy onslaught, and had no choice but to employ a little-used escape valve called “de novo lipogenesis” (new fat-making) to turn excess energy substrate into liver fat.
当人类开始在一顿饭里同时摄入脂肪和碳水化合物时，我们的新城代谢就开始紊乱了。肝脏线粒体无法处理能量的猛攻，只能动用很少使用的安全阀，即所谓的“脂肪再生”（de novo lipogenesis），将多余的能量基础转变为肝脂肪。