But the greatest scientific and public health goal in HIV/AIDS research still eludes us: the development of an effective HIV vaccine. This challenge has been particularly difficult because of the nature of the virus, particularly its ability to integrate itself into the genome of host cells, to readily mutate, and to conceal that part of its outer coat that would induce protective antibodies.
但是我们依然未能在HIV/AIDS的研究上最高的科学和公众健康目标，就是开发一种有效的HIV疫苗。因为病毒的性质而使得这一挑战变得特别困难，尤其是因为它有能力把自己融进寄主细胞的基因组中，随时准备进行变异，以及隐藏其会诱发保护性抗体的外壳部分。