For example, there are highly de-centralized ethics committees with varied qualities to protect human subjects. The EU directive does not regulate social and behavioral research while the US. does not regulate research that is privately funded and not related to drug licensing.
这一指令将欧洲的临床试验人体保护与美国的相一致。但是，在美国和欧洲范围内，这一系统都存在严重的缺陷和漏洞。例如，极为松散的不同伦理委员会保护人体实验对象。欧盟指令并不适用于社会和行为研究，而美国则并不管理由私人资助、并且与药品许可无关的研究。