The past decade has already yielded major advances in structure-assisted vaccine discovery, synthetic biology, systems biology, and immune monitoring. However, successfully translating these advances into the development of next-generation vaccines continues to be impeded by gaps in our understanding of the human immune response that protects against specific bacteria, viruses, or parasites.
过去十年产生了结构辅助疫苗发现、合成生物学、系统生物学和免疫监测的巨大进步。但是，成功地将这些进步转化为下一代疫苗的开发仍受到我们关于人体对具体细菌、病毒和寄生虫的免疫反应的了解不足的制约。