And where is nature’s gambit taking us? The proteins with the largest accumulation of structural defects are the prions, soluble proteins so poorly wrapped that they relinquish their functionally competent fold and form aberrant aggregates that may cause degenerative neuropathies.
那么，自然的开端是怎样造就了我们呢？结构性缺陷最多的蛋白质是朊病毒，这是一种可溶性蛋白质，遇水就会功能性折叠，形成一种畸变组合体，这种组合体可以引发退行性神经病变。