The host’s body produces its own version of the prion protein, and it is difficult to create a high-quality antibody against a body’s own components. As a result, rather than trying to induce immunity, researchers must develop prefabricated anti-prion antibodies that can be delivered directly to patients.
但一些问题也随之产生。宿主的身体产生了自己的朊病毒蛋白质，而创造针对宿主本身成分的高质量抗体是很困难的。因此，研究者的目标不应该是诱导免疫，而是开发可直接用于病患的预制朊病毒抗体。