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Question: INSIGHT-Japanese shoppers open their wallets, raising hopes for sustained revival

By Stanley White and Chehui Peh
TOKYO, Aug 14 (Reuters) - Japan's cautious consumers are starting to loosen up, spending more on cars and home appliances and offering hope that domestic demand - and not just exports - will be strong enough to reflate an economy that has been sluggish for many years.
The tightest labour market since the 1970s seems to be a playing a role. Temporary and part-time workers are getting paid more to help fill shifts, and that is helping lift sales.
Consumption was the main driver behind Japan's second-quarter economic growth, which expanded at an annualized 4 percent, gross domestic product data released on Monday showed, the strongest in more than two years and much higher than the growth achieved by the United States and the European Union.
"I ended a big project today, and I wanted to give a present to my girlfriend who has always been supportive, so I bought her a Tiffany necklace," said Yusuke Kawashima, a 29-year-old freelance software programmer in Tokyo.
"Quite a few of my friends have said they either had a pay raise or received a large bonus, so I think they'll be spending as well."
Wage hikes for part-time workers in Japan have accelerated, rising to 2.3 percent year-on-year in May from 0.7 percent in August 2016. Salaries for full-time workers, though, have been little changed.
Susumu Ikeda, 70, says shoppers are buying more at his musical instrument shop in Tokyo's tony Ginza shopping district, and senses the economy is taking a turn for the better.
"Some may be cynical about our growth, but compared to our worst we are getting much better," he said.
Furniture maker Nitori Holdings Ltd, convenience store leader Seven & i Holdings Co and coffee shop chain Doutor Nichires Holdings all reported rising domestic sales in their recent earnings reports.
Sales of new cars accelerated in April-June from the previous quarter, and GDP data showed higher purchases of appliances, such as air conditioners.
Private consumption - which accounts for almost 60 percent of GDP - rose in the second quarter at the fastest pace in more than three years, offering the most definitive sign yet that consumers have shaken off the impact of a sales tax hike in 2014.
For some, like 31-year-old Tokyo office worker Natsuki Abe, the economy just feels healthier.
"I do think the economy is doing better than it was before, but it´s just a feeling," she said. "My company is doing well, and I think I do have the money to spend on things that I like and want. I mainly spend on clothes, as I want to look good."
COMPETING FOR WORKERS
There have been previous such advances that have turned out to be temporary during Japan's many years of economic weakness since the early 1990s, with consumer spending often a culprit as it loses momentum.
This time may be different, though, some economists argue. That is because the unemployment rate is now low enough - 2.8 percent - to lift wages.
Many economists say Japan reaches full employment, the lowest level of joblessness before upward wage pressures arise, when the jobless rate falls to 3 percent.
Japan's aging population, and the resulting big drop in the size of its workforce, is a major reason for this.
"Wage growth will accelerate going forward, because companies have to raise wages to compete for new workers and to retain workers," said Takuji Adia, chief economist at Societe Generale. "This happens when the unemployment rate falls below 3 percent."
When Prime Minister Shinzo Abe took office in late 2012, the jobless rate was at 4.3 percent. Consumer spending boomed as a stock-market rally fuelled optimism about the new government but then lost momentum because wages were not rising that much.
Some of Abe´s structural reforms, such as narrowing the wage gap between contractors and full-time employees doing the same work, raising the minimum wage, and encouraging people to move to better-paying jobs, are also starting to pay off.
DEFLATIONARY MINDSET
One major concern is that Japan's consumer spending revival has yet to translate into faster inflation; core consumer prices rose a meager 0.4 percent in the year to June and inflation expectations remain weak.
The United States and Europe are also struggling to generate inflation despite improving growth, but Japan's case is peculiar because of the decades of deflation and stagnation following the collapse of the bubble economy in the early 1990s.
That's produced a deflationary mindset among many people that cannot easily be changed.
And as the country's population shrinks and ages, saving for the future has become a top priority for many.
"My husband's parents and my parents are getting old, and their pensions will not be enough for them to sustain themselves," said Chisa Tsubuki, a 28-year-old childcare worker. "So in anticipation for the future where nursing and healthcare costs will rise for us, we need to save."
Still, the economy looks like it is at long last starting to move in the direction the Bank of Japan predicted.
The BOJ's tankan survey shows more service-sector companies want to raise prices in the future. One example is family restaurant operator Skylark Co, whose president said earlier this month that it will hike prices from October.
"Consumers' perception of retail prices are changing, and people no longer buy something simply because it's cheap," a spokesman at the Takashimaya department store chain said.
"During our summer sale, the items that were not discounted actually sold better than the discounted items."
(Additional reporting by Ritsuko Shimizu; Editing by Martin Howell)

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LONDON, March 31 Following are five big themes likely to dominate thinking of investors and traders in the coming week and the Reuters stories related to them.
1/ JUMPY OVER TRUMP-XI
U.S. and Chinese presidents Donald Trump and Xi Jinping meet at one of Trump's resort hotels in Florida next week. The talks will set the tone of the relationship between the world's two biggest economies for the next few years and will reveal just how hard Trump is likely to play things with China on issues ranging from trade protectionism and currency manipulation to North Korea. Having been scuppered in his attempts to scrap Obamacare, Trump might see this as a good opportunity to show the American people some muscle flexing. He has already fired a few shots on Twitter, saying it will be a "very difficult" meeting and that the U.S. "can no longer have massive trade deficits and job losses."
* China downplays tensions with U.S. and Xi prepares to meet Trump
* Trump says trade gap will make China meeting 'a very difficult one'
* Trump to order trade abuses study, improve import duty collection
2/ BACK TO BASICS
Major currency markets are in one of those downbeat moments where no clear trend prevails. The opening salvoes of Donald Trump's presidency have not delivered the surge many predicted last year for the dollar. The belief in a steady reeling-in of European monetary stimulus that drove the euro higher in the past fortnight has also abated. No-one wants to back the pound through Brexit talks. And it would take a deeper and more longer-lasting correction in equities markets to build any faith in the yen. So possibly, we go back to the start and the higher U.S. yields that fundamentally support the greenback. GDP on Thursday was strong, some Fed officials predict up to three more hikes and another solid non-farm payrolls read on Friday would have the market thinking about some clear signalling for another rise in June. Unless Donald says, or tweets, different...
* Euro hits two-week low as inflation lags expectations
* Huge range of sterling forecasts clouds horizon
* Fed's Rosengren says sees 3 further rate hikes this year
3/ TAPER TEST
The first stage of the European Central Bank's slow withdrawal of monetary stimulus next week may throw into sharp relief the have- and have-nots in the bloc's debt markets. Weaker, so-called peripheral states like Portugal and Italy are seen as most dependent on the trillions of euros the ECB has spent over the past few years to shore up growth and inflation. But some investors worry an era of rock-bottom rates has papered over the cracks for countries which have not delivered the structural reforms needed to put their economies on a steadier footing. When the ECB from Monday trims its monthly bond purchases from 80 billion to 60 billion euros, it will be a major test of confidence in these countries and how they can withstand a return to normal monetary conditions in the future.
* Bonds of euro zone laggards quiver with ECB poised to trim QE
* Legitimate to review ECB pledge to keep rates at bottom: Coeure
* Spooked by yield rise, ECB wary of changing message again
4/ GORDHAN GETS ZUMA-ED
The revolving doors at South Africa's finance ministry are spinning again. After days of speculation, President Jacob Zuma finally reshuffled his cabinet, sacking his Finance Minister Pravin Gordhan. The decision to remove Gordhan -- seen as a guarantor of steady policymaking by many investors -- spooked markets, sending the rand tumbling and bond yields soaring. The turmoil also exposed deep rifts within the government. Zuma's deputy Cyril Ramaphosa told his boss he did not agree with the move, bank and business leaders in Africa's most industrialised economy have come out in force in their criticism and the opposition has mooted a motion of no-confidence against Zuma. Markets are closely watching out for reaction from credit ratings agencies which could see South Africa lose its coveted investment-grade status, making it more costly for the country to borrow.
* South Africa's ANC divided, Zuma weakened by cabinet reshuffle
* BREAKINGVIEWS-Gordhan exit is dual blow for South African debt
* S.Africa's Gordhan says intelligence report used to fire him "nonsense"
* Fitch: South Africa cabinet reshuffle signals policy change
5/ ONTO Q2
The first quarter began with a bang across global equity markets though Europe still lagged its developed market peers. Over the course of the three months, however, two things changed. Firstly, a steady stream of better economic data trumped the fuzzy risks about geopolitics drawing investors back into a stock market trading at valuation discounts to the others. Secondly, banks and mining stocks -- the biggest beneficiaries of the reflation rally -- gave way to tech, which ends Q1 as the best performing sector in Europe as well as the most expensive on a price-to-earnings basis. Global investor interest in Europe is stirring back to life and the hunt is on to seek out stocks and sectors that stand to benefit the most from a revival in economic growth, inflation and the brightest earnings outlook for the region in seven years.
* Europe sector performance YTD: bit.ly/2h3SjpY
* Investors bet on a quiet tech revolution in Europe
* Europe back in vogue as Trump bulls pull in horns – BAML (Compiled by Dhara Ranasinghe; Editing by Catherine Evans)


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Question: Bexhill skatepark bid’s welcome boost from Hastings Round Table

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Ambitious plans to provide Bexhill with a new skatepark, BMX track and games area have been given a welcome cash boost.
Hastings Round Table has agreed to donate £5,000 to help improve sports and recreation facilities at Sidley Recreation Ground.
Rother District Council agreed the project in December last year and committed £300,000 of funding.
The scheme includes a new concrete skatepark, an improved BMX track to meet regional standards and an all-weather multi-use games area for basketball and football.
Cllr Jim Carroll, the district council’s cabinet member for young people, sport and leisure, said: “We are delighted that Hastings Round Table has recognised the value of this project and have kindly and generously donated £5,000 in a bid to make it a reality.
“This is an ambitious project which will benefit the town as a whole and bring visitors to the area.
“We are fortunate to be working with Bexhill Burners BMX Club and the Bexhill Skatepark Action Group, who are helping us to promote the project and raise funds.”
The council is bidding for additional funding from Sport England to top up the capital money it has put aside for the project at the ground.
Skateboarder Harry Harmer originally highlighted the need to replace the existing facility back in 2016, saying the present one in Down Road near Bexhill Leisure Centre and King Offa Primary Academy had seen better days.
Hastings Round Table was able to make the £5,000 donation with funds raised primarily from the annual Hastings Beer and Music Festival.
This year’s three-day event runs until Saturday (July 7) at The Oval in Hastings.

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Ladies willl take to the catwalk next month as they stage a fashion show and shopping event to support Sheffield’s vulnerable young people.
The event staged by the Golddigger Trust is on May 2, from 7.30pm at The Well Church on Ecclesall Road.
Local ladies, aged from 16 – 50 years, will strut their stuff for the audience, including some ‘I’m the Girl I Want To Be’ course graduates, who will demonstrate just how much they now believe in themselves by modelling the beautiful bargains.
Tickets are £6 and include a free drink on arrival. After the show, attendees will be able to buy any of the clothes, in a wide range of sizes at a greatly reduced price. Brands include: M&S, Topshop, New Look, Wallis, Evans, Windsmoor, River Island and more.
Refreshments will be available and there will be a prize raffle.
See the website for tickets at www.golddiggertrust.co.uk.
The Golddigger Trust aims to unearth value and see real transformation in the lives of vulnerable young people.
The charity supports hundreds of vulnerable young people in Sheffield every year in local schools, youth groups and at their Centre for Young People on Psalter Lane.
This is achieved through mentoring, self-esteem and relationships courses, child sexual exploitation awareness sessions, football outreach and music and craft workshops, with thousands more helped through national projects and training programmes.
With mental health and emotional wellbeing issues among young people increasingly on the rise, demand for the support Golddigger Trust provides is huge. Community fundraising events are vital to raise both cash and awareness of issues surrounding teens.
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REGIONAL NEWS: Mum jailed after three-year-old boy found wandering streets naked and covered in faeces


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Question: Woman dies in Arizona after being hit by Uber self-driving car

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SAN FRANCISCO (Reuters) - A woman died of her injuries after being struck by a Uber self-driving vehicle in Arizona, police said on Monday, and the ride hailing company said it had suspended its autonomous vehicle program across the United States and Canada.
FILE PHOTO: Uber's logo is pictured at its office in Tokyo, Japan, November 27, 2017. REUTERS/Kim Kyung-Hoon
The accident in Tempe, Arizona, marked the first fatality from a self-driving vehicle, which are still being tested around the globe, and could derail efforts to fast-track the introduction of the new technology in the United States.
FILE PHOTO: A fleet of Uber's Ford Fusion self driving cars are shown during a demonstration of self-driving automotive technology in Pittsburgh, Pennsylvania, U.S. September 13, 2016. REUTERS/Aaron Josefczyk/File Photo
At the time of the accident, which occurred overnight Sunday to Monday, the car was in autonomous mode with a vehicle operator behind the wheel, Tempe police said.
“The vehicle was traveling northbound ... when a female walking outside of the crosswalk crossed the road from west to east when she was struck by the Uber vehicle,” police said in a statement.
A spokesman for Uber Technologies Inc said the company was suspending its North American tests. In a tweet, Uber expressed its condolences and said the company was fully cooperating with authorities.

Two unexplained storage tank failures at fertility clinics in Cleveland and San Francisco may have cost hundreds of women and couples their best chance to have children
Two unexplained storage tank failures at fertility clinics in Cleveland and San Francisco may have cost hundreds of women and couples their best chance to have children
The Trump administration accused Russia on Thursday of a concerted, ongoing operation to hack and spy on the U.S. energy grid and other critical infrastructure
The Trump administration accused Russia on Thursday of a concerted, ongoing operation to hack and spy on the U.S. energy grid and other critical infrastructure
Officials say multiple people have been killed and eight people have been taken to the hospital in the collapse of a bridge at a Florida university
Officials say multiple people have been killed and eight people have been taken to the hospital in the collapse of a bridge at a Florida university
With the likely demise of Toys R Us, a piece of Americana is disappearing
With the likely demise of Toys R Us, a piece of Americana is disappearing
End of an era: Toys R Us is going the way of stickball
End of an era: Toys R Us is going the way of stickball
A doctor says his hospital received 10 injured people - two of them critically - from the pedestrian bridge collapse at a Florida university
A doctor says his hospital received 10 injured people - two of them critically - from the pedestrian bridge collapse at a Florida university
Authorities said Friday that the cables suspending a pedestrian bridge were being tightened after a "stress test" when the 950-ton concrete span collapsed over traffic, killing at least six people and injuring 10
Authorities said Friday that the cables suspending a pedestrian bridge were being tightened after a "stress test" when the 950-ton concrete span collapsed over traffic, killing at least six people and injuring 10
The deadly collapse of a pedestrian bridge in Florida has cast a spotlight on a rapid construction technique widely used around the U.S.
The deadly collapse of a pedestrian bridge in Florida has cast a spotlight on a rapid construction technique widely used around the U.S.
Student who narrowly escaped after bridge collapse watched helplessly as structure fell apart
Student who narrowly escaped after bridge collapse watched helplessly as structure fell apart
Student watched helplessly as bridge came down on top of car
Student watched helplessly as bridge came down on top of car
Two weeks of odd news: Police say impaired bride crashes on her way to her wedding; two long-ago high school sweethearts in New Jersey marry in hallway where they met
Two weeks of odd news: Police say impaired bride crashes on her way to her wedding; two long-ago high school sweethearts in New Jersey marry in hallway where they met
Russia has announced it is expelling 23 British diplomats and threatened further measures in retaliation in a growing diplomatic dispute over a nerve agent attack on a former spy in Britain
Russia has announced it is expelling 23 British diplomats and threatened further measures in retaliation in a growing diplomatic dispute over a nerve agent attack on a former spy in Britain
A Border Patrol agent is going on trial for second-degree murder this week in a rare Justice Department prosecution of a fatal cross-border Mexico shooting.
A Border Patrol agent is going on trial for second-degree murder this week in a rare Justice Department prosecution of a fatal cross-border Mexico shooting.
(AP Photo/Brian Skoloff, File). FILE - This April 2, 2017 file photo made with a drone, shows the U.S. Mexico border fence as it cuts through the two downtowns of Nogales, Ariz. A U.S. border patrol agent is going on trial for second-degree murder in U...
(AP Photo/Brian Skoloff, File). FILE - This April 2, 2017 file photo made with a drone, shows the U.S. Mexico border fence as it cuts through the two downtowns of Nogales, Ariz. A U.S. border patrol agent is going on trial for second-degree murder in U...
US agent goes on trial in Mexican teen cross-border killing
US agent goes on trial in Mexican teen cross-border killing
Authorities say the brother of the teen charged with killing 17 people at a Florida school has been arrested for trespassing at the same school.
Authorities say the brother of the teen charged with killing 17 people at a Florida school has been arrested for trespassing at the same school.
Police have warned residents near the site of the latest explosion in Austin to remain indoors and to call 911 if they need to leave home before 10 a.m.
Police have warned residents near the site of the latest explosion in Austin to remain indoors and to call 911 if they need to leave home before 10 a.m.
(Nick Wagner/Austin American-Statesman via AP). FBI agents meet at the scene of an explosion in Austin, Texas, Sunday, March 18, 2018. At least a few people were injured in another explosion in Texas' capital late Sunday, after three package bombs deto...
(Nick Wagner/Austin American-Statesman via AP). FBI agents meet at the scene of an explosion in Austin, Texas, Sunday, March 18, 2018. At least a few people were injured in another explosion in Texas' capital late Sunday, after three package bombs deto...
New York City's deadly helicopter crash has prompted the National Transportation Safety Board to call on federal regulators to prohibit commercial flights that use passenger harness systems that do not allow for easy release.
New York City's deadly helicopter crash has prompted the National Transportation Safety Board to call on federal regulators to prohibit commercial flights that use passenger harness systems that do not allow for...
Attorneys for embattled casino mogul Steve Wynn say in court documents that he brokered a settlement with a second woman who accused him of sexual misconduct more than a decade ago.
Attorneys for embattled casino mogul Steve Wynn say in court documents that he brokered a settlement with a second woman who accused him of sexual misconduct more than a decade ago.
At least two people injured in another explosion in Texas' capital after three package bombs that detonated earlier this month in other parts of the city killed two people and injuring two others.
At least two people injured in another explosion in Texas' capital after three package bombs that detonated earlier this month in other parts of the city killed two people and injuring two others.
(Nick Wagner/Austin American-Statesman via AP). FBI agents work the scene of an explosion in Austin, Texas, Sunday, March 18, 2018. At least a few people were injured in another explosion in Texas' capital late Sunday, after three package bombs detonat...
(Nick Wagner/Austin American-Statesman via AP). FBI agents work the scene of an explosion in Austin, Texas, Sunday, March 18, 2018. At least a few people were injured in another explosion in Texas' capital late Sunday, after three package bombs detonat...
Mississippi's governor has signed the nation's tightest abortion restrictions into law, banning most abortions after 15 weeks' gestation.
Mississippi's governor has signed the nation's tightest abortion restrictions into law, banning most abortions after 15 weeks' gestation.
Police in a Phoenix suburb say one of Uber's self-driving vehicles has struck and killed a pedestrian.
Police in a Phoenix suburb say one of Uber's self-driving vehicles has struck and killed a pedestrian.
Former "Sex and the City" star Cynthia Nixon is running for New York governor.
Former "Sex and the City" star Cynthia Nixon is running for New York governor.
Your daily look at late-breaking news, upcoming events and the stories that will be talked about Tuesday:
1. POLICE MAKE DIRECT APPEAL TO BOMBER
In the search for answers to a series of explosions in Austin, Texas, authorities have come ahead with a simple plea to whoever’s behind the blasts: Talk to us.
2. SELF-DRIVING UBER STRIKES, KILLS PEDESTRIAN
The fatality in a Phoenix suburb is the first involving a fully autonomous test vehicle, prompting the ride-hailing company to suspend all road-testing of such autos in the U.S. and Canada.
3. TRUMP UNVEILS PLAN TO COMBAT OPIOIDS
The president calls for stiffer penalties for drug traffickers, including embracing a tactic employed by some of the global strongmen he admires: the death penalty.
4. DATA MINING CREATES STIR
A Trump-affiliated group, Cambridge Analytica, reportedly tried to influence elections using data, including likes, inappropriately obtained on tens of millions of Facebook users. What’s not clear is how effective that was.
5. WHAT’S NEXT FOR VLADIMIR PUTIN
As the Russian leader shifts into his next six-year term, he could groom a successor, scrap term limits, or create for himself a new behind-the-scenes position of power.
6. TURKEY VOWS NO LET-UP
President Erdogan says he intends to keep pressure on a U.S.-backed Syrian Kurdish militia — and could expand Turkey’s military offensive into other Kurdish-held areas across northern Syria and even into neighboring Iraq.
7. MISSISSIPPI LAW STANDS ALONE
The state’s governor signs the nation’s tightest abortion restrictions into law, banning most abortions after 15 weeks.
8. HOW TO STAY HEALTHY WHILE FLYING
Worried about catching a cold or the flu on an airplane? Get a window seat, and don’t leave it until the flight is over, researchers advise.
9. NCAA TOURNAMENT HAS NEW LOOK
Sixteen teams are now left. Top seeds Virginia and Xavier are gone. Ditto No. 2 seeds North Carolina and Cincinnati.
10. WHO’S STEPPING ONTO POLITICAL STAGE
Former “Sex and the City” star Cynthia Nixon says she’s running for New York governor.


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Question: Once in a century hat trick history made in NHL openers

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The hats were flying on the first two nights of the NHL season.
Connor McDavid, Alex Ovechkin, Wayne Simmonds and Brandon Saad each recorded a hat trick in his team's season opener. It's the first time four different players scored at least three goals in his season opener in 100 years, since the NHL's first two games back in 1917.
Ovechkin's hat trick that led the Washington Capitals to a 5-4 shootout victory at Ottawa was the 18th of his career, most among active players and tied for 20th-most all time. Reigning MVP McDavid picked up his second already at age 20.
The hat tricks by McDavid and Simmonds were the first, respectively, in franchise history for the Edmonton Oilers and Philadelphia Flyers in a season opener. Saad's hat trick in a 10-1 drubbing of the Stanley Cup champion Pittsburgh Penguins was the first by a Chicago Blackhawks player in a season opener since Hockey Hall of Famer Bobby Hull in 1965.

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Mariah hotness reminds us that Instagram International modeling hotties can be both intellectual and beautiful as we check this collection of all the Kansas City mainstream media links. Take a peek: Celebrations for the opening of a $568 million shipping terminal - tied to the U.S. by Kansas City Southern operations - were muted due to worries about policy changes that could harm U.S.-Mexican trade.
Start the conversation, or Read more at Tony's Kansas City.


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Question: Did Hope Hicks White House Love Triangle Cost Her Her Job?

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Hope Hicks’ previously involvement with Corey Lewandowski may have had some serious ramifications in her recent relationship with Rob Porter! Check out the wild report about Hope’s love triangle here!
Apparently, some serious romantic drama went down in the Trump administration. Outgoing White House Communications Director Hope Hicks, 29, and ex-White House secretary Rob Porter, 40, may be completely over, but it might be largely due to the machinations of one Corey Lewandowski, 44, former campaign manager to the president. In an interview with New York magazine, Porter’s second ex-wife said that Porter was desperately trying to get her to remove a blog post accusing him of alleged physical abuse because he was afraid someone was “going to send it to the media.” She added, “He did not name names, but he implied that there was a former staffer from the White House who was unhappy with him and was out to get him and take him down and somehow had gotten wind of my blog post.” Originally, she assumed the ousted staffer was Steve Bannon, but later told New York magazine it was Corey.
Now, here’s where it gets even stranger. Corey and Hope had been involved before having their own dramatic split after a May 2016 fight had her screaming, “I am done with you!” And according to sources, a vengeful Corey was emotionally invested in finding out who Hicks was dating in an obsessive kind of way. According to New York magazine, one source claimed he had “Single White Male characteristics,” another claimed he thinks he should “control” Hicks; another said he had “raw feelings” about the breakup. Well, following revelations of his alleged domestic abuse and that he couldn’t pass an FBI background test, Rob resigned and he and Hope split. However, the New York magazine piece makes it clear that the real reason Hope resigned was over her personal unhappiness working in the White House.
While she reportedly considered quitting on earlier occasions, she finally resigned the day after she told investigators that she told “white lies” on the behalf of the president. Click here to see pics Hope and Melania Trump’s fashion!

The Majority of Us Have Had Nightmares About Work . . . and the Most Common One Is Sex with a Coworker?


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Question: Imperial Brands sticks to full-year guidance

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March 30 Imperial Brands, the world's fourth-biggest tobacco company, stuck by its full-year guidance on Thursday as it said it would match first-half earnings expectations at constant currency and reported rates.
The maker of Winston, Gauloises and other cigarette brands said revenue and earnings per share were expected to be up strongly for the six months ending March 31, driven by the benefit of currency translation.
It anticipates a currency translation benefit on net revenue and profit of about 13 percent to 14 percent at current exchange rates.
However, Imperial Brands said it expected lower revenue and profit at constant currency rates, impacted by the phasing out of an 300 million pound investment plan.
First-half revenue at constant currencies was primarily driven down by a deterioration in industry volumes, as previously guided, Imperial Brands said. (Reporting by Esha Vaish in Bengaluru, editing by David Evans)

London's FTSE 250 index was down 0.5% to 19,676.22 in afternoon trade as investors keep a close eye on political developments in light of last week's hung parliament. Outsourcer Mitie was the standout gainer after it withheld its final dividend as it tumbled into losses, with the market impressed by the new management team's expectations of a quick return to growth in underlying profits this year.
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Question: U.S. Cheese Market Trend, Demand, Share, Future Growth, Key Players Review and Industry Report by 2023

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Market Overview:
Globally the cheese market is mainly driven by increasing consumption of dairy products included in daily diet of consumers. Increasing adaptation of European lifestyle and their food culture in U.S. is influencing the market growth. Applications of different types of cheese with various flavors in various sectors of food industries are supporting the product’s sale. Cheese is extensively used in convenience foods, ready-to-eat meals, fast-foods and even in confectionery products. The high demand of the product across these industries is seen as a potential opportunity for its market.
Increase in consumer acceptance of ethnic cooking, such as Italian & Mexican, the demand for cheese and cheese products are expanding at an exponential rate. Being the largest cow producer in the world, U.S. is found to be a hub for fine qualities of cheese. The cheese varieties depend on the milk used as a raw material for cheese production. Large cow variety supports the high volume yield of milk which has a direct impact on the large volume of cheese production. Washington State itself in the U.S. is found to have nearly 273,000 dairy cows with varieties such as Jerseys, Guernseys, Brown Swiss and others. The increase in consumption of Italian and Mexican food preparations has raised the demand for cheese as cheese is one of the major constituent in these cuisines. For instance, pizza and pasta have become popular dishes consumed all over the world. Cheese is considered to be a vital ingredient in these food preparations.
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Latest Industry Updates:
Dec 2017 Naturipe Farms has been awarded with New York Produce Show and Conference for its Naturipe Snacks product line that combines fruit, cheese and nuts into one portable package.
July 2017 Land O’Lakes has launched a new product range of organic cheddar cheese powder in order to respond the consumers demand for natural dairy ingredients free from food coloring and dyes.
April 2017 Dean Foods Company and KRAFT Macaroni & Cheese have announced their collaboration to expand its business portfolio.
March 2017 Vermont Creamery has become independent operational subsidiary of Minnesota-based Land O’Lakes. This activity will help the company to produce fresh and aged goat cheeses, cultured butter and fresh dairy at the production unit.
Major Key Players:
Key players are focusing on expansion of their cheese business. From six years, strategy of expanding the cheese business holds around 33% of strategy share by key players. Acquisitions and partnership are two main factors which are contributing more than 34% of strategy share as it helping company to enhance their cheese production capacity and to capture more market share in U.S. and other regions in North America.
The key players profiled in U.S. cheese market are Land O’Lakes, Inc. (U.S.), Dairiconcepts L.P. (U.S.), The Kraft Heinz Co. (U.S.), Leprino Foods Company (U.S.), Associated Milk Producers Inc. (U.S.), Foremost Farms USA (U.S.), and Dairy Farmers of America Inc. (U.S.) among many others.
Industry Segments:
The U.S. Cheese Market has been segmented into type, form, packaging material, and distribution channel.
On The Basis of Type: Mozzarella, Cheddar, Cottage, Swiss, Blue, and Others
On The Basis of Form: Cubes, Slices, Tubs, Balls, and Others
On The Basis of Packaging material: Paper, plastic, metal, and others
On The Basis of Distribution Channel: Store Based (Hypermarket/ Supermarket, Retail Stores, Specialty Stores, Convenience stores, and others) and Non-Store Based
Access Report Details @ https://www.marketresearchfuture.com/reports/u-s-cheese-market-2842
Regional Analysis:
Overall cheese and curd import in U.S. has increased by 4.61% from the year 2012 to 2016. Italy is the major cheese importing country to U.S. has import share of 17% in the year 2016 which due to increasing popularity and consumption of Italian cheese in United States. U.S is importing more cheese form New Zealand and import of cheese from New Zealand has increased significantly. Import of cheese from France has declined by 3.55% from the year 2012 to 2016. Maximum cheese imports form U.S. are other countries which contributes around 50% of import share.

Sealed Paper Packaging Market provides detailed market segment level data on the international market. The Sealed Paper Packaging Market report addresses forecast and growth patterns by company, regions and type or application from 2017 to 2021.
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In this report, the global Sealed Paper Packaging market is valued at USD XX million in 2016 and is expected to reach USD XX million by the end of 2022, growing at a CAGR of XX% between 2016 and 2022.
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Sealed Paper Packaging Market by Product Type: Paper Boxes, Paper Pouches, Other Sealed Paper Packaging Market by Application: Packed Snacks, Groceries
Confectioneries, Cosmetics, Pharmaceutical, Other, The research analysts provide an elaborate description of the value chain and its distributor analysis. This Sealed Paper Packaging Market industry report study provides analysis based on Geographical Regions, Manufacturers, Applications, Types, Drivers, Opportunities, and Challenges which enhances the understanding, scope and application of this report. The Sealed Paper Packaging Market analysis is provided for the international market including development history, competitive landscape analysis, and major regions development status.
Top key players of Sealed Paper Packaging Market: American Packaging, Sonoco, International Paper Company, MeadWestvaco Corporation, Hood Packaging Corporation, BillerudKorsnas, Pack Plus Converting, Tyler Packaging Ltd, Advance Paper Box
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To provide information on competitive landscape, this report includes detailed profiles of Sealed Paper Packaging Market key players. For each player, product details, capacity, price, cost, gross and revenue numbers are given.
Sealed Paper Packaging Market by Region: North America, Europe, China, Japan, Southeast Asia, India
Sealed Paper Packaging Market Effect Factors Analysis: Technology Progress/Risk, Substitutes Threat, Technology Progress in Related Industry, Consumer Needs/Customer Preference Change, Sealed Paper Packaging Market Forecast 2017-2021, Sealed Paper Packaging Market Capacity, Production, Revenue Forecast 2017-2021, Sealed Paper Packaging Market Production, Consumption Forecast by Regions 2017-2021, Sealed Paper Packaging Market Production Forecast by Type 2017-2021, Sealed Paper Packaging Market Consumption Forecast by Application 2017-2021, Sealed Paper Packaging Market Price Forecast 2017-2021. Major Topics Covered in Sealed Paper Packaging Market Research Report Are as Follows: Marketing Channel, Direct Marketing, Indirect Marketing, Market Positioning, Pricing Strategy, Brand Strategy, Target Client, Distributors/Traders List
The report then estimates 2017-2021 market development trends of Sealed Paper Packaging Market. Analysis of upstream raw materials, downstream demand, and current market dynamics is also carried out. In the end, the report makes some important proposals for a new project of Sealed Paper Packaging Market industry before evaluating its feasibility.


Question:
i found this news title. can you represent it to find an explanatory news article?

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The provided query could be '['represent the title to find an explanatory news article', 'Rabbit rescues prep for abandoned bunnies']' and the positive '['Represent the article to find a fitting news title.', 'Rabbit rescue organizations are preparing for an influx of surrendered and stray bunnies as Easter weekend comes to an end.\nKaylie Ngo, president of London, Ont.,-based Hoppy Hearts, said the peak season for her rescue starts in June and July — and much of the volume stems from bunnies that were hastily purchased as Easter gifts for kids.\nBunnies are usually given as gifts when they’re about eight weeks old, Ngo said. But after a few months, their personalities start to shift.\n“They start becoming very hormonal and active little teenagers that like to poop and pee and start destroying things,” she said.\nThe executive director of Rabbit Rescue Inc. in Cambridge, Ont., said oftentimes, parents who buy the animals for their kids don’t understand what they’re getting into.\n“They’re really similar to cats and dogs, not like hamsters and gerbils,” Haviva Porter-Lush said. They can’t be kept in a small cage, for instance. Porter-Lush recommends keeping them in a pen or a dedicated room to themselves.\nAnd they’re also more like cats and dogs in terms of cost than many people realize, she added.\n“When people see them in the store for $30 or $40, they don’t realize that, say, ’in five or six months time, I’m going to need to spend $300 to $700 getting my rabbit spayed.”’\nNgo said that sometimes, a lack of veterinary care can be an issue for rabbit owners.\n“Despite being the third most popular pet in North America, they are still considered an exotic pet by many veterinarians, and it can be really, really hard to find a good veterinarian to care for the rabbit,” she said.\nBoth Hoppy Hearts and Rabbit Rescue Inc. send rabbits that are up for adoption to foster homes — neither organization has a dedicated shelter space.\n“It’s hard, because it’s a busy time of year and we get full very quickly,” said Porter-Lush, adding that they’re limited by the number of people who have agreed to act as foster families.\nIn fact, Ngo said her rescue has become so busy that it’s had to stop accepting owner-surrendered bunnies. Right now, she said, Hoppy Hearts is only taking in rabbits that have been abandoned outside.\n“Even if only temporarily, being put outside is a death sentence,” she said.\nSo when they get the call about a domestic rabbit that someone has spotted outside, they act fast. Ngo said that at least two people will go out to the scene and try to corral the rabbit into a pen.\nThen, they scan the bunny for immediate health concerns: dental issues, parasites and injuries. If it’s all clear, they go ahead and get the bunny spayed or neutered as quickly as possible.\nBoth Ngo and Porter-Lush recommend fostering a rabbit before eventually adopting one — it’s less commitment, and gives people a chance to see whether a rabbit is a good fit for their household.']' and the negative '['represent this text to find a news title for it', "2:35 Saburo Masada visits site of his internment for first time since 1942 Pause\n3:58 Boulders, concrete flown in to strengthen damaged Oroville spillway\n1:36 'The King,' (Elvis impersonator Will Kettler) is in the house for Valentine’s Day weddings\n3:02 Meet Alexander Mickelthwate, the third conductor candidate for the Fresno Philharmonic\n0:33 Fresno police arrest two after string of armed robberies\n1:39 Most babies should be exposed to peanuts earlier, according to new guidelines\n2:08 Fowler girls chase Central Section's lone unbeaten regular season\n1:31 Worn Poverello House warehouse leaks, in need of repairs\n1:17 Apartment complex in Oakhurst floods"]'

Question: White House claims Trump's policies could have prevented NYC attack

Represent this text to find a news title for it.

Washington (CNN) The White House said Monday that President Donald Trump's preferred immigration policies would have prevented the suspect in an attempted New York terrorist attack from entering the country.
The White House offered no evidence about where the suspect was radicalized.
The suspect, Akayed Ullah, 27, came to the US from Bangladesh in 2011 on a visa for children of siblings of US citizens, the Department of Homeland Security confirmed Monday. Ullah is a lawful permanent resident, or green card holder, spokesman Tyler Houlton said.
The administration also immediately pointed to so-called chain migration in relation to the attack, a term that describes immigration to the US based on family connections.
"The suspect ... benefited from extended family chain migration," Houlton said in the statement.
Shortly after that, White House press secretary Sarah Sanders made the case that Ullah would not have been in the US if Trump's preferred immigration policy were implemented.
The President has repeatedly called for an end or restrictions on "chain migration," and has endorsed a bill from Republican Sens. Tom Cotton of Arkansas and David Perdue of Georgia that would drastically reduce the number of immigrants who can get green cards to stay in the US.
"We know that the President's policy calls for an end to chain migration, which is what this individual came to the United States through, and had his policy been in place, then that attacker would not have been allowed to come into the country," Sanders said.
Sanders could not answer a follow-up question about whether the individual had been radicalized in the United States in the years he's lived here, as have recent terrorist attackers in the US who were not natural born citizens.
She said the incident -- which caused non-life-threatening injuries to three others in addition to Ullah, who had an amateur explosive device strapped to his body -- indicated the need for policy changes.
"This attack underscores the need for Congress to work with the President on immigration reforms that enhance our national security and public safety," Sanders said. "We must protect our borders, we must ensure that individuals entering our country are not coming to do harm to our people and we must move to a merit-based system."
Critics have pointed to the fact that only a small fraction of green cards are given out each year based on employment as evidence of the need to revamp the US immigration system. Family connections, including spouses, children and extended family, account for a large share of green cards given out each year.
US citizens over age 21 are able to sponsor siblings for visas to the US, and Ullah's type of visa is given to the children under 21 years of age of those siblings. Those families still must meet eligibility requirements to enter the US and are screened and interviewed.
Cotton and Perdue's bill would cut the number of green cards given out per year by roughly half, by sharply cutting the number of family-based categories for visas and by transforming the employment-based green card system from one based on employers' needs to one that heavily favors highly skilled, highly educated, English-speaking immigrants.
That bill lacks wide support in Congress, including among many Republicans, though Trump has pushed for it to be part of a deal to save the Deferred Action for Childhood Arrivals policy he has opted to end.

0:49 White House is 'keeping a close eye' on crisis at California's Oroville dam Pause
2:23 One arrest as protesters block DeVos from D.C. middle school
3:36 Treasury Secretary Mnuchin announces Venezuela sanctions
1:26 Who's at the door? Principal visiting homes of each of her 1,003 students
4:07 Federal judge temporarily halts Trump’s travel ban
2:19 Warren: Shocked to find 'truth was out of order' on the Senate floor
0:51 Trump administration eases Russian sanctions to allow U.S. tech exports
1:44 Trump administration putting 'Iran on notice'
1:53 French officials: Louvre attack was 'terrorist in nature'


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Question: Boomers want to retire in style

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Baby boomers are not content to retire the same way previous generations did. Just as they have since they began entering the world in 1946, they’ve got demands now — and senior housing and retirement communities are working to keep up.
As of 2016, people aged 65 and older numbered nearly 50 million across the country, according to the U.S. Census Bureau. That’s 15 percent of the total population. And the boomer generation, born between about 1946 and 1964, is well into crossing that age 65 threshold.
“One thing we know about baby boomers is that they redefine everything,” said Nancy Carr, the assistant state director of communications for AARP’s Maryland chapter. “And they’re redefining aging as well.”
What that means in practice is more options. Boomers have a strong sense of individuality, said Elinor Ginzler, Jewish Council for the Aging senior director and director of the organization’s Misler Adult Day Center.
“[There is] as much variety in the housing market [for seniors] as possible to match the variety of people,” Ginzler said. “The healthcare piece won’t go away but, in my opinion, it’s all the stuff around it — what they call amenities, but I call necessities.”
Ginzler pointed to Leading Age, an association for aging service providers, changing its term from “continuing care retirement communities” to “life plan communities” because “care” and “retirement” aren’t concepts that resonate with the boomer generation.
One of the main trends both Ginzler and Carr identified was fitness and wellness. Communities are offering not only high quality fitness facilities and classes, but also related elements like nutrition classes, jogging trails and gardening.
Leisure World, a community of 8,000 people aged 55 and older in Montgomery County, just opened a 5,400-square-foot fitness center nearly twice the size of its previous one with updated equipment, more strength training options and a studio room for barre, dance or yoga classes. So far, the response has been immensely positive, said Maureen Freeman, the director of communications for Leisure World.
“A couple weeks ago when they did the ribbon-cutting at 9 a.m., the place was just packed with people,” she said.
Leisure World will also be rolling out a new internal portal residents can access online anytime. It will allow residents to request services, directories and calendars of events. It’s not just an element incoming and current residents want, she said, but one “which I think upcoming generations will be expecting.”
Integrating technology is another place where these communities are upping their game, said Carr, pointing to smart homes and medical apps that track health and medication information.
“While use of technology and smartphones continues to grow among the senior community, for boomers it’s not a new thing and they’re going to want a place to continue that use,” Ginzler said.
Boomers are also, increasingly, avid foodies, Carr said, wanting to know where their food comes from and wanting more than one dining option. Ginzler added that many of these communities will have both high-end kitchens and chefs.
Mainly, Ginzler said, residents “want to be as enriched as they were in the life they built” outside of those communities. Leisure World, for instance, has more than 80 groups and clubs, including a popular Center for Lifelong Learning, which hosts speakers and classes on a variety of subjects.
At the center of these communities is healthcare, and that will likely remain the case, Carr said. Healthcare providers are trying to anticipate the changing health needs for coming generations.
“People are living longer,” she said, “and there’s increasing emphasis on creating dementia-friendly spaces and living situations.”
And boomers don’t want to waste those extra years. They’re prepared to demand both style and quality of life, Ginzler said. n
hmonicken@midatlanticmedia.com

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Traveling is good for the soul. We all know that. What many don't know, however, is how good it can be for Americans to travel abroad right now.
Start the conversation, or Read more at Noozhawk.


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Question: Rodgers leads Packers to NFC North title

Rodgers declared that the Packers could "run the table" when they were 4-6 and they did just that, finishing the regular season on a six-game winning streak. Green Bay (10-6) enters the NFC playoffs as the No. 4 seed and will host the No. 5 seed, the New York Giants, in the opening round of the playoffs.
Both teams qualified for the postseason earlier in the evening when Washington lost to the New York Giants. The Lions (9-7), who failed in their bid to win their first division title in 23 years, wound up as the No. 6 seed. They will travel to No. 3 Seattle in the first round.
Rodgers completed 27-of-39 passes for 300 yards. Adams caught six passes for 31 yards, while rookie Geronimo Allison caught four passes for 91 yards and a touchdown. Fullback Aaron Ripkowski had a combined 76 rushing and receiving yards, including a touchdown for GreenBay, which won its fifth division championship in six seasons.
Matthew Stafford completed 26-of-41 passes for 347 yards with two touchdowns and one interception for the Lions. Detroit running back Zach Zenner picked up a combined 110 rushing and receiving yards, including a touchdown, and Golden Tate caught six passes for 77 yards and a touchdown.
The Packers grabbed a 17-14 lead early in the third on Rodgers' 3-yard pass to Adams. Jordy Nelson, held to one catch in the first half, caught three passes on the drive.
Rodgers spun out of trouble and bought time before finding Allison on a 10-yard scoring play with 10:02 remaining. The extra point was missed, leaving the score at 23-14.
Matt Prater's 54-yard field goal with 7:52 left pulled Detroit within six.
A Detroit penalty for too many men on the field extended Green Bay's next possession. Rodgers then clinched the victory with a 9-yard strike to Adams.
Stafford heaved a 35-yard touchdown pass to Anquan Boldin with 13 seconds left. Green Bayrecovered the onside kick, ending any remaining suspense.
The Lions led 14-10 at halftime.
The game was scoreless heading into the second quarter. Detroit kicker Matt Prater hooked a 39-yard field goal try at the start of the quarter and Green Bay then drove 71 yards to take the lead.
Rodgers hit tight end Jared Cook twice on the drive and finished it off with a 7-yard scoring pass to Ripkowski. It was Ripkowski's first career receiving touchdown.
Detroit tied the score at 7-all on its next possession. Stafford's 35-yard pass to TJ Jones on a third-and-15 situation set up Zenner's 1-yard scoring run with five minutes left in the half.
The Lions' two-minute offense produced another touchdown. Stafford's 3-yard slant pass to Tate with 23 seconds remaining completed a 69-yard scoring drive.
Mason Crosby nailed a 53-yard field goal for Green Bay on the final play of the half.
NOTES: The Lions played without two of their starting offensive lineman, as RT Riley Reiff (hip) and C Travis Swanson (concussion) were inactive. RB Theo Riddick was placed on injured reserve Saturday with a wrist injury. ... The Packers did not have WR Randall Cobb (ankle) for the second straight week and C JC Tretter (knee) was also inactive. RB James Starks (concussion) was declared out earlier in the week. ... QB Matthew Stafford surpassed the 30,000 career passing yards mark during the first half. He reached that milestone in an NFL-record 109 games, five games faster than previous record-holders Dan Marino and Kurt Warner.

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Subscribe to The MMQB: 10 Things Podcast and it will be waiting in your feed first thing Monday morning. (For non-subscribers, there is sometimes a lag.) The Week 17 show will be available soon…
As always, Andy and I are very available through social media channels. We moved the mailbag portion of the podcast to the Thursday show, when we’ll answer as many questions as humanly possible (playoffs, offseason, coaching carousel, draft, anything is fair game):
Andy Benoit on Twitter and Facebook
Gary Gramling on Twitter and Facebook
Thanks for listening, you are the best, and please leave a review on iTunes if you like the show!
This week’s show:
1. Washington’s collapse, what’s next for Kirk Cousins?
2. Aaron Rodgers remains unstoppable as Packers win NFC North
3. Falcons rise up to become NFC favorites
4. A job Opening in Denver, and more QB questions in Oakland
5. Chiefs win the West while Chargers (unwisely) fire Mike McCoy
6. Patriots clinch top seed behind Brady, Edelman and a new face at receiver
7. Seahawks win ugly again, 49ers become first team with back-to-back one-and-done coaches
8. Tom Savage hurt for Houston, opening up QB conundrum again
9. The Lightning-ish Round: Steve Smith Sr.’s finale (and home arcade), Cam Newton’s nightmare continues, Colts spot Jags 17 then Luck takes over, Bears D disappoints again, Romo shines in cameo at Philly (Mark Sanchez does not), Browns nearly make it a winning streak, Cards finish strong and Fitz is a league leader, Bills start GM’s QB and go nowhere
10. Week 17 Awards
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Question: A Determined Father Bravely Faces His Fear of Heights Head On In His Effort to Peer Over a Cliff

While on a family excursion to Dún Aonghasa, Inis Mor in County Galway, Ireland, a son named Alex captured footage of his father facing his crippling fear of heights head on, literally. While nervously laughing, the brave man lay flat on the ground and began slowly crawling to the edge of the cliff to get a peek at the stunning view of the sea down below. Kudos to him.
Dad faces some demons…My dad won’t let a crippling fear of heights keep him from peering over the edge. Well maybe.
via reddit

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Whoa.. a bit too freaky for me! #AGT
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Question: Froome named for Giro d'Italia as probe into test continues

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Britain's Chris Froome celebrates on the podium in Madrid after winning last year's Spanish Vuelta.
Britain's Chris Froome celebrates on the podium in Madrid after winning last year's Spanish Vuelta. Francisco Seco
TEAM Sky has named Britain's Chris Froome in their team for the Giro d'Italia, which starts next month, despite the ongoing investigation into his adverse doping test.
Briton Froome, 32, is fighting to clear his name after an increased dosage of asthma medication at the Vuelta a Espana last year threw up an adverse analytical finding from a urine sample.
The four-time Tour de France winner's sample showed double the allowed limit of Salbutamol.
He has denied any wrongdoing and is free to race because he is not suspended.
Froome, who has not ridden in the Giro since 2010 and has never won it, will be aiming to become the first rider to complete the Giro-Tour double for 20 years.
Italian Marco Pantani was the last man to achieve the feat, in 1998.
The three-week 3546.2km Giro begins in Jerusalem on May 4.
The Tour de France starts two months later.
- Reuters

With the transfer season drawing to a close, there are still a selection of talented riders without a team for 2018. We list five who are looking for a home
As the 2017 season comes to a close with Il Lombardia and stage races in Turkey and China, a handful of WorldTour riders remain without contracts for the 2018 season. Among them are Tour de France and Vuelta a España stage winners, and a Critérium du Dauphiné victor.
Here are five top riders still free to talk to teams for next season:
Alexey Vermeulen (LottoNL-Jumbo)
Alexey Vermeulen spent five hours in the escape during the Road World Championships for team USA and for a 2018 contract. The 22-year-old’s current two-year deal with Dutch WorldTour team LottoNL-Jumbo is at its end with no hope for renewal insight.
He told Peloton magazine: “I am as motivated as I have ever been to stay at the top level of the sport. I look forward to proving that they made the wrong decision!”
Teams looking for a developing helper in stage races could do well to hire Vermeulen because he climbs and time trials well. This year, he helped George Bennett win the Tour of California overall and his team-mate Koen Bouwman win the Critérium du Dauphiné stage to Tullins. After his work, he held on to place fifth in Tullins.
Marco Coledan (Trek-Segafredo)
Marco Coledan, silver medallist in the 2015 Madison World Championships with Elia Viviani, will no longer race for Trek in 2018. The team announced its roster last week without the Italian’s name.
Coledan had a string of top placings that earned him a place with Trek-Segafredo for 2015. Perhaps he is known better for his involvement in the ‘Pay-to-Race’ case in Italy, where his former team manager at Bardiani and others were found to have accepted money for team contracts and charged additional money for riders to break their contacts. Coledan was suspended for 15 days for not testifying.
>>> Cycling transfers 2018: All the ins and outs from the WorldTour
The 29-year-old, without any major results recently, may be forced to leave the top WorldTour ranks for a Professional Continental team.
Matti Breschel (Astana)
Matti Breschel for years served as a domestique in the Grand Tours and in the classics alongside Fabian Cancellara and others in teams Saxo Bank/Tinkoff, Rabobank and Cannondale. The Dane even has a Vuelta a España stage win and a trophy from the Dwars door Vlaanderen.
However, after one year with Astana, he is looking for a new team. Danish newspaper Ekstra Bladet reported an unnamed source as saying that the 33-year-old’s time is over in the team’s blue colours.
“Matti will continue to race at the top-level,” said his agent and dad, Tom Breschel. “Right now we have nothing in place, but there is some time. However, it has not been easy given teams will be cut from nine to eight riders in the Grand Tours. That means many teams will cut two to three men out of their rosters.”
Christophe Riblon (Ag2r La Mondiale)
After two stages wins and 13 years together, Ag2r La Mondiale will not continue with Frenchman Christophe Riblon in 2018. The 36-year-old is looking to continue racing, but remains doubtful.
“Honestly, I have no complaints,” he told L’Equipe. “[General Manager] Vincent Lavenu helped me to pass pro [in 2005], he believed in me when I was already 24 years old.
>>> How many Chris Froomes could you buy for Neymar’s £198m record football transfer fee?
“I’m still confident that I can be very good, that I can help a captain… If it ends here, I’d feel it’s too soon even if I’ve been doing it for 13 years.”
Riblon said that this May and June he had his best power numbers in five years. However, Ag2r is passing on handing him a new contract and is building a team around Romain Bardet, third overall in the last Tour.
Janez Brajkovic (Bahrain-Merida)
Slovenian Janez Brajkovic, 33, is looking for a new team after one year in the new Bahrain-Merida squad.
The small climber won his home race, the 2012 Tour of Slovenia, the 2010 Critérium du Dauphiné and back in 2007, the Tour of Georgia. This year, he led Bahrain in the overall classification at the Tour de France, recording 45th. The result was far from the ninth place he achieved in 2012.
The Tour of Guangxi in China is his last planned race with Bahrain. However, do not expect him to fade away. He stepped down before to the second-tier Professional Continental ranks with United Healthcare after years racing for Discovery Channel, RadioShack and Astana, and still returned to the top.
Bahrain-Merida’s Jon Insausti is looking, as well. Ondrej Cink after one year racing professional on the road, will leave the team and return to mountain bikes.


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Question: Trump’s military strikes against Syria, ISIS unlikely to keep North Korea in check

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David Ignatius echoes a lot of what we’re hearing these days when he writes that Donald Trump has tasted some foreign policy successes lately. But he’s really saying that the president is embracing what Obama called the Washington playbook.
There’s a playbook in Washington that presidents are supposed to follow. It’s a playbook that comes out of the foreign-policy establishment. And the playbook prescribes responses to different events, and these responses tend to be militarized responses.
When a president begins to use that playbook, apparently the word “success” takes on a whole different meaning. Merely the use of military force gets defined as success, whether or not any tangible progress has been made.
For example, the case most often cited as a success for Trump is his bombing of an airfield in Syria after Assad used chemical weapons against his own people. To judge whether or not that was a success, we need to know what the goals were. At this point Assad still has his chemical weapons (or the ability to manufacture them) and the airfield that was targeted was used the next day to continue bombing civilians.
Perhaps the goal was to send a message to Assad. If so, those who are calling it a success have completely ignored the fact that up until a couple of days prior to the Syrian president’s use of chemical weapons, the Trump administration had been sending the message that he was free to do whatever he wanted. Calling that a success stretches the meaning of the word beyond recognition.
Ignatius credits Trump’s successes to the fact that he has developed a competent national security team and is listening to their advice. While it might be true that they have convinced him of the importance of NATO and of the need to work with China to deal with North Korea, let’s take a look at what else they’ve been up to in just three months:
Those can hardly be called successes and, instead, indicate a very dangerous trend. The counterterrorism approach of the Obama administration (especially following his speech on the topic in May 2013) was to do everything possible to limit civilian casualties so as not to provide recruitment fodder for groups like ISIS. We saw the results with the imposition of more oversight of the use of drones and the slow, steady approach to the re-taking of Mosul from ISIS.
Perhaps because that strategy didn’t involve the use of things like the “mother of all bombs,” it didn’t garner a lot of attention. But it was working. There were even those who were predicting that, because these efforts were so successful, Trump would wind up getting credit for defeating ISIS simply because it would happen in his watch. Rather than build on that success, the president and his national security team seem intent on snatching defeat from the jaws of victory.
If talking tough and indiscriminate bombing is all it takes to convince Washington that Trump has a successful foreign policy, we are headed for exactly the kind of “dumb wars” we’ve seen in the past – the kind we were supposed to have learned from. Rather than putting a check on this kind of thing from Trump, the media seems to be cheering him on. Once again, they are heading towards making themselves culpable for the needless death and destruction that is sure to come.


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Question: California uses late run to pull away and beat Arizona State

1:06 First baby of 2017 in the Fresno area born at Clovis hospital Pause
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1:18 Troubles continue at Fresno's Hotel California
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2:45 Understanding the Electoral College: 'A process not a place'
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0:56 Baby needs a new home

The Hawks rode strong defensive efforts and the big-play ability of their offense to dethrone the Mustangs 41-21 at AT&T Stadium on Friday afternoon.


Question: Exxon CEO urges New York prosecutor to rethink climate change probe

DALLAS (Reuters) – Exxon Mobil Corp’s chief executive said on Wednesday that he hopes the new attorney general in New York “comes to a different conclusion” than predecessor Eric Schneiderman on a climate change probe into the world’s largest publicly traded oil producer.
Schneiderman, who resigned earlier this month after allegations of physical abuse by four women that he denied, had alleged Exxon withheld information about its internal climate change discussions and misled the public about what it knew. Exxon has long denied the charges.
The investigation has spread to other states, including Massachusetts, and has put Exxon squarely in the middle of the ongoing debate about fossil fuels and climate change.
CEO Darren Woods, who spoke at Exxon’s annual shareholder meeting in Dallas, said he was “committed to being part of the solution on climate change.”
Woods added he has not reached out to Barbara Underwood, who was appointed to replace Schneiderman. He said he was not sure if Exxon attorneys have talked to Underwood or her office.
“I’m real confident on where we stand. I hope whoever comes in steps back and takes an objective look … and comes to a different conclusion,” Woods said.
Underwood, a Democrat appointed by the New York State Legislature, has said she will not run for election to a full term this November. At least six candidates of various political backgrounds have announced their candidacies.
“Let’s see what that election brings,” Woods said.
New York State Comptroller Thomas DiNapoli, who oversees state pension funds that hold about 11.5 million Exxon shares, has also long criticized the company’s response to climate change and voted against a slate of 10 board nominees at the company’s annual meeting.
“The fund cannot support board directors who refuse to acknowledge substantial risks to Exxon’s bottom line and fail to help it transition to a lower carbon future,” DiNapoli said in a statement. All 10 board nominees were approved.

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0:59 Got flowers yet? Bellingham florist ready for Valentine's Day Pause
1:01 Rescued gulls are released at Tacoma Tideflats
4:25 Seattle Channel segment examines rights of sanctuary cities, features undocumented mother of three
4:11 What you need to know about the massive Oroville dam emergency in California
5:01 Trump talks about Russia accusations, business dealings in first post-election press conference
0:48 Trump counters on Putin question, says 'Our country's so innocent?'
2:43 Haley on Russia: I don't think we can trust them
1:20 Washington AG calls apellate ruling against travel ban a 'complete victory'
1:32 Press Secretary says press should focus more on leaks than Flynn's resignation


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Question: Bruce Morcombe's message to bus fare rorters

BRUCE Morcombe has a message to children rorting the "no child left behind" policy created after his son Daniel went missing at a bus stop.
"The no child left behind policy was not designed as a freebie for kids," Mr Morcombe said.
The Daniel Morcombe Foundation received "two or three calls a week" from concerned parents who felt the public transport service and "not connected or left their child behind".
Data obtained by the Sunday Mail showed TransLink received almost 1000 complaints across the southeast since the 2014 financial year about failure to pick up child passengers.
Mr Morcombe told the Daily though he was aware there was another side to the story.
"We are aware it not always the bus company's fault," he said.
"Sometimes some students at high schools play the system. They say 'I've lost my money', but there's the 'no child left behind policy.
"That's fine, if you do it maybe once a term because you couldn't afford it that week. But those who do it day after day are playing the system."
The figures obtained by the Sunday Mail under Freedom of Information showed there were 315 grievances recorded in the year to June 2016, 351 in the year to June 2015 and 321 in the year to June 2014.
TransLink said it was able to substantiate only 28 cases relating to a driver failing to pick up or drop off a child in the 2016 financial year.
"Safety is our number one priority and every incident reported involving a child is treated seriously and investigated thoroughly," a spokesman said.
Mr Morcombe said the policy was "designed to keep kids protected" after Daniel was left behind while waiting for a bus and was then abducted and murdered in 2003.
"We just think the policy is great and should continue," Mr Morcombe said.
"But it is not designed to make it free for a child to get the get bus indefinitely."
Mr Morcombe did not want the policy changed though.
"We definitely want the no child left behind policy implemented and used properly," he said.
"It is an honesty system, people abuse things all the time. It is more a reflection on them personally.
"Honestly is the best policy. The rorters need to be made aware to please not do it anymore."

A husky recovering after being dragged from a burning home, video of an Adelaide Centrelink customer's shocking racist rant, we speak to the daughter of a woman killed in a shopping centre carpark, as the driver pleads guilty, police hunting a mysterious serial bomber in Texas.


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Question: $1.18 to $1.58 a litre: Are you paying the most for gas in B.C.?

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Gas prices across B.C. vary, with lowest in Vernon and highest in – you guessed it – Metro Vancouver
Everyone is talking about the soaring price of gas lately – and not just in B.C.’s most gridlock-prone cities.
According to GasBuddy.com, gas stations in Vernon are offering the lowest prices across the province as of Tuesday afternoon, sitting steady at about 117.9 cents per litre. Prince George is next in line, with 119 cents per litre on average.
Some of the highest costs, meanwhile, are being recorded in Metro Vancouver, to the tune of 154 cents and above.
Dan McTeague, a senior petroleum analyst with Gasbuddy.com, has pointed to a months-long national trend in which Canadians are seeing an average increase of 15 cents a litre compared to last year.
Causes include increased demand, gas shortages, and refineries shutting down for spring maintenance.
READ MORE: B.C. gas prices to hit highest levels in years: forecast
Here’s where gas prices stand today across the province:
Cranbrook:
Victoria:
Surrey:
Vernon:
Castlegar:
100 Mile House:
Revelstoke:
Port McNeill:
Summerland:
Trail:
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After rising sharply over the past several weeks, gas prices rose just a couple of pennies last week and not at all since Friday.
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So, you're taking a road trip for the Fourth of July weekend, and you're about to leave the state.
Do you fill up on gas now, or do you wait to fill up after you cross the border?
Making the wrong decision could cost you more than $10 a tank, depending on where you're heading.
"Watch out for those state lines," says Patrick DeHaan, senior petroleum analyst at fuel-station-finding app GasBuddy.
Gas prices averaged $2.86 per gallon Tuesday, according to AAA, hitting a four-year high for Independence Day travel.
Here's some advice before you head out – all prices according to GasBuddy:
1. Fill up in Arizona, not California
The price disparity between these two states is extreme.
Arizona averaged $3.06 per gallon as of Tuesday, while California averaged $3.73, according to GasBuddy.
At those prices, a 15-gallon fill-up is $10.06 more expensive in California.
2. Fill up in Texas, not New Mexico
If you're road-tripping in the Southwest, price differences can be significant. This is another good example.
The price of fuel in Texas, where oil refineries are clustered, averaged $2.66 on Tuesday. In New Mexico, it was $2.91.
That means you'd save $3.75 in Texas on a 15-gallon tank.
3. Fill up in Louisiana, not Texas
But Texas is more expensive than Louisiana, which is also a hot spot for refineries.
Prices averaged $2.59 in Louisiana on Tuesday, compared with $2.66 in Texas.
Generally, though, "anywhere in the South" is a good place to fill up, DeHaan said. "They’re right in oil’s backyard. Plus, low taxes."
4. Fill up in Ohio, not Michigan
Ohio is much more forgiving on the pocketbook than its rival to the north.
With prices averaging $2.79 on Tuesday, Ohio was sharply lower than Michigan's $2.96.
5. Fill up in Virginia, not West Virginia
Going white-river rafting in West Virginia? Sounds fun.
But fill up first in Virginia, where prices are 21 cents lower at $2.61.
6. Fill up in West Virginia, not Pennsylvania
West Virginia doesn't look so bad when you see prices in Pennsylvania, which averaged $3.01 on Tuesday, compared with West Virginia's $2.82.
7. Fill up in Massachusetts, not Connecticut
At $2.91, Massachusetts isn't exactly an oasis of cheap gas.
But it's still cheaper than neighboring Connecticut at $3.08.
8. Fill up in South Carolina, not North Carolina
North Carolina is 14 cents higher at $2.66.
Come to think of it, fill up in South Carolina no matter where you're heading. It's the cheapest gas state in the country, according to GasBuddy.
Follow USA TODAY reporter Nathan Bomey on Twitter @NathanBomey.
Copyright 2017 USATODAY.com


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Question: Jeremy McLellan, who mocked India’s cow vigilantes, is known for his religious comedy

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Jeremy McLellan is no stranger to offending the religious sensibilities of those who don’t find some things funny. His Jeremy McLellan show (video above) explores his unique brand of religious comedy. It covers his experience of being a Christian comic performing for Muslim audiences.
Ever since the American US stand-up comedian made a Facebook post about the self-styled “cow vigilantes” who killed a man in Alwar, Rajasthan, he has faced relentless criticism from Hindutva social media activists.
McLellan explains the philosophy of his comedy thus: “...to make people feel like they are not going crazy. To make people feel not alienated or depressed or misunderstood, to understand their concerns, to laugh at the world and the ridiculousness of the situation.”
He also explains why Uber is the perfect app. “It was invented by a Jew so that when a Christian gets drunk, he can call a Muslim to come pick up him,” he said. “So it all works out very very perfectly.”
McLellan’s comedy in known to poke fun at religious absurdities and often covers controversial subjects. In the video below, he talks about police brutality, feminism, ephebophilia, marriage, and plantations.

The voice of the devil belongs to a 24-year-old Englishman who just failed his driving test.
That devil is @s8n, and the man behind the boisterous Twitter account is Michael Rothwell of Manchester. Since inheriting the dormant Twitter account from an acquaintance in 2015, Rothwell has amassed more than 200,000 followers thanks to a hilarious mix of topical musings, demented life advice and more recently, President Donald Trump’s rise to the top of American politics. For Satan, Trump has become a very relevant comedic gold mine.
“I just use the hatred of Trump to my advantage really because everyone refers to him as Satan or Satan’s son, so I tried using that to my advantage to get a huge reaction from my tweets,” Rothwell told the Observer in his first formal interview.
Please stop running for president, I need you back in hell where you belong @realDonaldTrump — Satan (@s8n) November 6, 2016
I miss you son @realDonaldTrump — Satan (@s8n) August 18, 2015
Rothwell’s humble upbringing in Manchester is the exact opposite of what you’d expect the Prince of Darkness’ doppelgänger to have. His father worked for a bed manufacturer and his mother was a cleaner. The family attended church once in awhile but wasn’t very religious. Rothwell attended Elton High School before enrolling at Berry College, where he studied information technology. His favorite comedian is Scotland’s Frankie Boyle, who is best known for stirring up controversy. He works in retail and took his driving test Feb. 9 for the first time in a Mini.
Rothwell started tweeting from @s8n in July 2015. He approached each tweet as if the devil himself was thumbing a cell phone while walking the planet among us. This style was an immediate success. On Aug. 18, 2015, Rothwell’s first Trump-related tweet was retweeted 157,000 times and posted on Tumblr to the tune of 255,000 notes.
Are you coming home for Christmas this year? @realDonaldTrump — Satan (@s8n) December 21, 2016
A fellow Twitter user who’s also seen his tweets gobble up mounds of attention is Jonathan Sun, a doctoral student at MIT and comedian behind the popular @jonnysun. The social media darling believes Rothwell’s success is not just predicated on topical tweets.
“Parody accounts, by nature, are one-liners. Most are flash-in-the-pan, zeitgeisty one-liners that reflect something popular, immediate and viral, but some one-liners are evergreen,” Sun told the Observer over email. “‘What if Satan had a Twitter account’ is an evergreen one-liner for social media—it will always appeal as a parody account idea because Satan is a constant figure in society.”
Society’s endless fascination with good and evil—God and the devil—is timeless and newsworthy. A Facebook page dedicated to a wisecracking God on Facebook has more than 3.2 million followers and stirred up news coverage in early February when it lost its blue verified check mark. The God Twitter account, @TheTweetOfGod, once had more than 2.3 million followers before its founder David Javerbaum, who worked for Jon Stewart’s “The Daily Show” for 11 years, called it quits. Javerbaum parlayed his social media laughs into real world dollars in the form of the book, “The Last Testament: A Memoir By God” and the play, “An Act of God.” Exposure to this sort of Twitter success is very new to Rothwell.
In January, Rothwell was approached by the hardware company TarDisk. The Boston-based startup offered a free flash memory drive for Rothwell’s Mac in exchange for a tweet. Rothwell obliged and hopes it’s just the start of such luck.
In the meantime, fans like Lucien Greaves, co-founder and spokesman for The Satanic Temple, hopes @s8n “helps people to laugh more freely and mercilessly at superstition.”
“With an American theocracy leering just upon the horizon and the revival of mainstream paranoid Satanic Panic tales (such as the embarrassingly idiotic “PizzaGate” conspiracy theory),” Greaves said. “It’s more important now than ever that we can point at such unreasoned absurdity and laugh.”


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Question: Baird Analyst Breaks Down Apple's In-House Manufacturing, Road To $1 Trillion (NASDAQ:AAPL)

Apple Inc. (NASDAQ: AAPL) is reportedly looking to manufacturer its own screens in-house for the first time, but this shouldn't necessarily come as a surprise.
The Analyst
R.W. Baird's Will Power discussed Apple's outlook during CNBC's "Squawk Box" on Monday.
The Thesis
Reports that Apple is looking to manufacturer its own screens can be traced back to its 2014 acquisition of LuxVue, in which it acquired dozens of patents related to Micro LED displays, Power said.That's why it shouldn't necessarily come as a surprise, but for the time being, it's not clear if Apple will proceed with in-house manufacturing over time.
There are reasons for members of Apple's supply chain to be concerned, especially if they're left out of the ecosystem or seen their involvement diminish. At the same time, there's no reason why suppliers of components can't introduce their own innovation that "helps the entire ecosystem" through continuous improvements in technologies.
Power said expectations call for Apple to release two different size OLED iPhone devices in 2018. The release of new devices could come at a time when Apple continues to grow its top-line at a double-digit rate and its upcoming cycle could help support this trend.
Price Action
Shares of Apple were trading lower along with the broader market, down 1.9 percent at $174.54 Monday afternoon.
Apple supplier Universal Display Corporation (NASDAQ: OLED) was crushed, down 13.3 percent at $107.50.
Related Links:
Qorvo's Increased Competition For Apple Business Prompts Sell-Side Downgrade
BofA: Should Apple Cut iPhone Prices This Year?

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In case you missed it, here are some of Benzinga's top stories from Monday, March 19, 2018.
NVIDIA Analyst Stays Bullish
Ahead of a March 27 analyst day, B Riley FBR analyst Craig Ellis says NVIDIA Corporation (NASDAQ: NVDA) is as much of a buy as it ever was. Learn more about the analyst’s thesis in Shanthi Rexaline’s “B Riley FBR: Nvidia Remains Attractive For Growth Investors Ahead Of Analyst Day.”
The United States Vs. AT&T
Feeling confused about why the court trial AT&T Inc (NYSE: T) is facing in its bid to merge with Time Warner Inc (NYSE: TWX) is such a big deal? Get caught up by checking out Elizabeth Balboa’s “The US Vs. AT&T-Time Warner: Inside The M&A Trial Of The Decade.”
See Also: KeyBanc: The Tesla Model 3 Is Fast And Elegant, But Maybe Too Simple
Apple Supplier Falls On Rumor
Shares of Universal Display Corporation (NASDAQ: OLED) fell as much as 19 percent Monday after a report that Apple Inc (NASDAQ: AAPL) was looking to produce displays for its own devices at a secret U.S. facility. Learn more, in Jayson Derrick’s “Universal Display Under Pressure Amid Report Apple Wants To Develop Its Own Screens.”


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Question: AstraZeneca immunotherapy wins first approval in bladder cancer

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FILE PHOTO: The logo of AstraZeneca is seen on a medication package at a pharmacy in London April 28, 2014. REUTERS/Stefan Wermuth/File Photo
U.S. regulators have approved AstraZeneca's key immunotherapy drug durvalumab as a treatment for bladder cancer, marking the first commercial green light for a product the company hopes will go on to sell billions of dollars.
The approval, while expected, marks a milestone for the British company, which expects new cancer drugs to help revive its fortunes following patent losses on older blockbuster products like cholesterol pill Crestor and Nexium for heartburn.
Bladder cancer itself is a relatively small initial market, where AstraZeneca is lagging behind rivals Bristol-Myers Squibb and Roche whose immunotherapies are already approved for the condition.
Durvalumab's big commercial opportunity lies in previously untreated lung cancer, where key clinical trial results, including with combination therapy, are due in June or July.
Leerink analyst Seamus Fernandez sees durvalumab capturing a modest 10 percent of the estimated $2.3 billion global bladder cancer market, while AstraZeneca in 2014 put the drug's peak sales in all cancers at $6.5 billion, including combination use.
The U.S. Food and Drug Administration (FDA) said late on Monday it granted accelerated approval to AstraZeneca's drug to treat advanced bladder cancer in patients whose disease had progressed despite chemotherapy.
The drug, which will have the brand name Imfinzi, works by helping the body's immune cells kill cancer, offering an alternative to toxic chemotherapy. While not without side effects, such immuno-oncology treatment has the potential of longer-lasting efficacy, although it comes at a high price.
AstraZeneca said the average wholesale acquisition cost of durvalumab would be around $15,000 a month.
"This first approval for Imfinzi is an important milestone in our return to growth," said AstraZeneca Chief Executive Pascal Soriot.
The drug belongs to a new class of medicines called PD-L1 inhibitors that block a mechanism tumors use to evade detection from the immune system.
It was approved by the FDA for use in patients with locally advanced or metastatic urothelial carcinoma, by far the most common form of bladder cancer, regardless of their status for the amount of PD-L1 protein on their cancer cells.
Durvalumab won accelerated approval, which enables the use of therapies for serious conditions to fill an unmet medical need based on data the FDA believes is likely to predict a clinical benefit. AstraZeneca is required to conduct trials to confirm actual benefit to patients.
The FDA also approved a complementary diagnostic from Roche that can be used with the drug to assess PD-L1 levels. Studies have shown patients with high PD-L1 are more likely to do well on durvalumab, although such a test is not required for its use.
Durvalumab is being tested on its own and also in combination with another immune system-boosting therapy called tremelimumab in various cancers.
The medicine is the latest immunotherapy to be approved by the FDA, after nods for treatments developed against various cancers by Bristol-Myers Squibb, Merck & Co, Roche, and a collaboration between Germany's Merck KGaA and Pfizer.
AstraZeneca shares were up 0.3 percent in early London trading on Tuesday.
(Editing by Susan Thomas and Jason Neely)

AstraZeneca Drops Phase III Asthma Drug as Company Posts Disappointing 2017 Financials
By Alex Keown
AstraZeneca saw revenues and product sales fall over the course of 2017. In a year-end financial report for 2017, AstraZeneca said its total revenues declined 2 percent to $22.46 billion and product sales fell 5 percent to $20.15 billion.
Those failing numbers put a strain on Chief Executive Officer Pascal Soriot’s pledge of achieving $45 billion of annual revenue by 2023. The company said it did see a much stronger fourth quarter in comparison with the first three and Soriot sees that as a sign things are turning around.
“AstraZeneca’s revenues improved over the course of the year, a sign of how our company is steadily turning a corner. Strong commercial execution helped us bring our science to more patients, making the most of our exciting pipeline,” Soriot said in a statement.
Soriot added that the company’s strategy is propelled by a strong pipeline that includes oncology drugs Tagrisso and Lynparza. Soriot also noted that cardiovascular drug Brillinta and diabetes drug Farxiga both hit blockbuster status this year, each bringing in more than $1 billion in revenue.
As AstraZeneca looks to drive revenue from core products, the company quietly dropped some drug candidates as well. One of the candidates it dropped was tralokinumab, a Phase III asthma drug. AstraZeneca said it discontinued development of the drug after it failed to meet endpoints in three separate trials. Tralokinumab, an IL-13 human immunoglobulin-G4 monoclonal antibody, was being developed for the treatment of uncontrolled asthma.
While AstraZeneca kept tralokinumab in its own development as a potential asthma treatment, the company did sell off rights to the drug for dermatological uses. In July 2016, Denmark-based LEO Pharma struck an agreement with AstraZeneca worth up to $1 billion for the rights to develop tralokinumab.
In addition to tralokinumab, AstraZeneca also cut another experimental asthma treatment, AZD9898. On ClinicalTrials.gov, the company noted that the therapy, which was acquired from Sweden-based Orexo, was terminated based on an interim review of Phase I data.
As the company looks to achieving that $45 billion in revenue, it will have to continue to field numerous blockbuster drugs. Its PARP inhibitor Lynparza is an example of a drug that AstraZeneca is finding new indications for. Earlier this month, the U.S. Food and Drug Administration approved Lynparza for use in patients with deleterious or suspected deleterious germline BRCA-mutated (gBRCAm), human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer who have been previously treated with chemotherapy in the neoadjuvant, adjuvant or metastatic setting. That approval makes Lynparza the first PARP inhibitor approved for metastatic breast cancer, and the only PARP inhibitor approved beyond ovarian cancer.
Another AstraZeneca cancer drug, Imfinzi (duravulumab), could generate nearly $4 billion in annual sales if it gains regulatory approval for use in lung cancer. The FDA is set to rule on the use of Imfinzi, a PD-L1 inhibitor, in lung cancer this year. The drug has been approved for some bladder cancers. The company filed the New Drug Application based on strong Phase III results.
Shares of AstraZeneca are up slightly in morning trading to $35.73 as of 9:31 a.m.
BioSpace source:
https://www.biospace.com/article/unique-astrazeneca-drops-phase-iii-asthma-drug-as-company-posts-disappointing-2017-financials