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E.g. given '['Represent this title to get a news article that provides more details about it', 'Sweep of Clemson shows NC State primed to be factor in ACC']' it should be close to '['Represent the article to find a fitting news title', "FILE - In this May 24, 2015, file photo, North Carolina State head coach Elliott Avent watches his team during the ninth inning of an Atlantic Coast Conference NCAA college baseball tournament championship game against Florida State, in Durham, N.C. North Carolina State quietly built an impressive first-month record against a soft nonconference schedule. The Wolfpack’s first sweep of Clemson in 21 years has pushed them to the national forefront in college baseball. (AP Photo/Karl B DeBlaker, File) (Photo: The Associated Press)\nNorth Carolina State quietly built an impressive first-month record against a soft nonconference schedule. The Wolfpack's first sweep of Clemson in 21 years has pushed them to the national forefront in college baseball.\nAfter being ranked No. 19 or lower a week ago, they were as high as No. 6 in the polls Monday after three weekend wins over the former No. 1 RPI team.\nIt's heady times for coach Elliott Avent and a program that long has been an also-ran in the Atlantic Coast Conference. The Wolfpack (18-3), who haven't won an ACC regular-season title since 1986 or conference tournament championship since 1992, are out to their best start since the 1999 team opened 20-3.\nThe Wolfpack entered this week with the best record in the ACC and, at 5-1, lead their division by a game over Wake Forest.\nThey're third in the nation with 38 home runs — matching their 2017 total — and their .326 batting average ranks seventh. They're scoring 8.1 runs per game.\nBrett Kinneman leads the nation with 32 RBIs and is tied for first in home runs with 11. Will Wilson (.364), who has reached base in 36 straight games, and Evan Edwards (.350) each have hit six homers and are among eight everyday players batting .313 or better.\nBrian Brown (4-0) has an 0.57 ERA in 31 1/3 innings to lead a staff that has a 2.86 ERA, down from 4.13 last year, and reliever Kent Klyman has allowed no earned runs in 16 innings. Klyman and Reid Johnston have combined for seven saves.\nIN THE POLLS\nOregon State (18-1), Florida (18-4) and Stanford (14-2) remained the top three teams in the D1Baseball.com and Baseball America rankings Monday. Collegiate Baseball newspaper also has the Beavers No. 1, followed by Stanford and Auburn (19-2). The Tigers, off to their best start since 1999, won two of three against Texas A&M over the weekend.\nSEC EXPANDS REPLAY\nThe Southeastern Conference, for league games only, has expanded the use of replay review and implemented a new experimental challenge system for head coaches.\nNew types of plays that can be reviewed: force or tag plays, calls involving whether a base runner passes a preceding runner before such runner is out, hit-by-pitch calls, tag-up plays, placement of runners when the umpire's placement of runners following a boundary call, and interference for the purpose of breaking up a double play.\nThe umpire crew chief may initiate review of these six calls with a head coach's challenge at any time during a game or at the crew chief's discretion beginning with the eighth inning, or sixth inning in a designated seven-inning game.\nSix permanent reviewable calls will remain in effect for all conference and nonconference games. Those are fair or foul calls, home runs, catch plays in the outfield or foul territory, certain catch plays in the infield, spectator interference and scoring plays at home plate.\nThe crew chief can initiate review of those six calls at any time.\nUnder the head coach challenge rule, a coach is limited to two challenges per conference game.\n3 MORE NO-HITTERS\nThis season's Division I no-hitter total is up to 13 after three more last week.\nSouthern California freshman Kyle Hurt combined with Austin Manning and Connor Lunn for the Trojans' first nine-inning no-hitter since 1986 in a 2-0 win over Utah on Thursday.\nShane McClanahan and Carson Ragsdale combined for South Florida's first no-hitter since 2010 in a 12-0 win over Army on Friday. Texas Southern's Michael Villanueva threw a seven-inning no-hitter in a 10-0 win over Prairie View A&M on Saturday.\nTOUGH PATCH FOR FROGS\nTCU (10-7), which has reached the College World Series four straight years, has lost four of its last five games for its roughest stretch in five years. The Horned Frogs has hit .192 over the stretch, and nine of the 32 runs against them have been unearned. They open Big 12 play this weekend at home against Kansas State.\nRUN OF THREE-BAGGERS\nWofford had a national season-high five triples in a 12-6 win over Siena on Saturday. The Terriers had a triple in the fourth inning, one in the fifth, two in the sixth and one in the seventh. The triples led to eight of the 12 runs.\nCopyright 2018 The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed."]' but not to '['this news article should be represented to find a fitting news title:', '0\nShares\nThe Florida Gators are looking to cap off their season on a high note, but it will come with a tough test against an Iowa team they say is looking to prove something in the Outback Bowl.']'.

Question: Huntington's disease: Drug trial shows promising results

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(CNN) For the first time, an experimental drug has reduced levels of the toxic protein that causes Huntington's disease in humans.
Huntington's disease is an inherited disorder in which mutant forms of the huntingtin protein damage nerve cells in the brain.
The new drug, Ionis-HTTRx, was shown to be safe in humans and lowered levels of mutant huntingtin protein in the nervous systems of trial participants.
"The results of this trial are of groundbreaking importance for Huntington's disease patients and families," said Sarah Tabrizi, director of University College London's Huntington's Disease Centre, who led the trial. "The key now is to move quickly to a larger trial to test whether the drug slows disease progression."
The trial involved 46 patients at early stages of the disease who were enrolled across nine centers in the UK, Germany and Canada. Initial results were announced Monday.
Each patient received four doses of either the new drug or a placebo, injected directly into spinal fluid so it could easily reach the brain. For those receiving the drug, the dose was increased over time, and safety was monitored throughout, according to a statement.
Concentrations of the toxic protein were measured in the patients' spinal fluid before and after the injections.
Among people receiving Ionis-HTTRx, the team saw a significant decline in levels of mutant huntingtin, which causes symptoms of the disease, with higher doses having greater impact. This is the first time the protein has been lowered in patients with the condition.
"The results are encouraging, as it shows delivering therapeutic agents of this type is feasible and well-tolerated and the treatment has done what it said it would: namely, drop the relevant protein levels," said Roger Barker, professor of clinical neuroscience and honorary consultant neurologist at the University of Cambridge, who worked with six patients involved in the trial.
"The question is whether this is enough to make a difference to patients and their clinical course, and that we will have to wait for bigger trials," he said.
The team now plans to conduct a larger-scale trial in hundreds of patients across multiple centers, said Ed Wild, a principal researcher at UCL's Huntington's Disease Centre, who worked on the trial with Tabrizi.
Hunting down huntingtin
Huntington's disease is an inherited neurodegenerative disorder in which nerve cells in the brain are damaged, causing uncontrolled movements, changes in behavior and emotions, and altered cognition.
The disease typically begins affecting people between the ages of 30 and 50 and gets progressively worse over time. Children of a parent with the disease have a 50% chance of inheriting the mutant gene.
An estimated 30,000 Americans are living with the disease. About 10,000 people in the UK have it, and a further 25,000 are at risk.
The condition is caused by a mutation in the huntingtin gene, which encodes the huntingtin protein, which is needed for normal development before birth and thought to help brain cells function, though the exact function is unknown . The mutant form of this protein accumulates and binds together to become toxic to certain brain cells, eventually killing them.
A drug with the ability to reduce levels of the toxic protein would mean progression of the disease could be slowed or even stopped.
"The details of this study have not been peer-reviewed or published yet, so the scientific community simply does not know yet how robust the findings are," noted Tara Spires-Jones, deputy director of the Centre for Discovery Brain Sciences at the University of Edinburgh, who was not involved in the research.
"With that caveat in mind, the approach used in this trial has excellent potential to prevent Huntington's disease," she said, "and if the next stage of larger trials live up to their promise, this will be a breakthrough."
How the drug works
The drug consists of a single strand of DNA that targets genetic material within brain cells, called mRNA, that helps translate genes into proteins.
In this case, the drug specifically sought out mRNA that helps translate huntingtin genes into huntingtin proteins and stopped production of the protein -- both the healthy and toxic forms.
"Less of the protein is made," Wild said, adding that the healthy form of the protein is known to play a vital role in early childhood development but not necessarily during adulthood, whereas the toxic form damages nerve cells in adults. "That protein is the cause of all of the problems" in Huntington's disease.
'A game-changer'?
It's hoped this form of drug could be adapted to target proteins in other currently incurable brain disorders, such as Alzheimer's disease.
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By changing the DNA sequence in the drug, researchers can target any mRNA, Wild said. In other neurodegenerative diseases, "there is at least one protein you would like to partially reduce," he said. One example is tau protein in Alzheimer's disease. "This is proof of principle you can inject these drugs into spinal fluid; they get into the brain and reduce harmful proteins."
"This is a potential game-changer, not only for Huntington's disease patients but also for genomic medicine in general," said Philippa Brice of health policy think tank the PHG Foundation.
"Though more work needs to be done, if gene silencing lives up to this promise, we could be on the brink of some of the personalized treatments that patients with severe genetic diseases need so badly. But this will also raise further questions for society and for policy-makers about how best to use such a powerful technique," Brice said.
The drug was developed by Ionis Pharmaceuticals but has been taken over by Roche, which will lead the development of the next, larger trial and handle future licensing of the drug, Wild said. The full results of the trial and plans for future trials will be presented next year.

Merck & Co. will stop its study of an experimental Alzheimer's drug in people with mild or moderate symptoms because interim results showed "virtually no chance" of any benefit.
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Question: A third of Scotland’s roads are deemed to be in need of repair

Around a third of Scotland’s roads are in need of repair, an investigation has revealed.
The report found that around 30 per cent of A-roads in Scotland between 2015 and 2017 were classed as red or amber, which means they were either earmarked for inspection or definitely required work, while on B-roads, the figure rose to 35 per cent.
The figure was far higher than in England, where only 3 per cent of A roads and 5 per cent of minor roads were classified as being in a poor condition, although the data is collected in a different way.
A total of 2,220 kilometres of A-road in Scotland was in need of repairs, the analysis found, while a further 2,571 of B-road required attention.
However, while the amount spent on local roads per head of population in Scotland over the past five years totalled £657.61, the UK average expenditure is just £436 per head, while the per-head figure for national roads of £621.46 in Scotland, was almost twice the UK average of £312 per head.
The BBC’s Shared Data Unit analysed eight years of public data from the National Improvement Service for Local Government in Scotland. The areas of Scotland with roads potentially needing repairs across all classifications are Argyll and Bute, Eilean Siar, North Ayrshire, Inverclyde and Stirling.
Experts said that Scotland’s bad winter weather was to blame for the worse condition of roads north of the Border.
Luke Bosdet, public affairs spokesman for the AA, said: “The poor condition of Scottish roads comes as no surprise. It is a long-running problem, often illustrated by the views of AA members. Pothole location will be dictated by a number of factors, such as amount and type of traffic, amount and standard of roadworks, and nature of the road.
“As for Scotland, I don’t think they really know where to start. Filling potholes with recycled plastic bottles and bags (which one assumes will leak plastic particles into the drains) just smacks of desperation.”
Gareth Howell, executive managing director at AXA Insurance, said: “While we don’t have specific data relating to the condition of roads across the UK, from our experience it makes sense that roads in Scotland need more work as they tend to have colder and wetter weather, which damages the road surface. At the same time, even though there are more roads in need of work in Scotland compared to England, there are fewer drivers and less traffic compared to say, the south east of England, so we don’t see an increase in the proportion of claims in the area.”
In Argyll and Bute, 45 per cent of roads were classed as amber or red, while in the Western isles, 44 per cent needed repair. In West Lothian, however, the figure was only 18 per cent.
The Scottish Government has responsibility for trunk roads in Scotland, with the maintenance of local roads the domain of local authorities. Politicians warned that council’s road maintenance budget had been cut by the government.
Colin Smyth, Scottish Labour’s rural economy and connectivity spokeman, said: “Local authorities have been forced to pass on SNP government cuts by slashing the road maintenance budget by 21 per cent since 2011.”
Jamie Greene, Scottish Conservative transport spokesman, said: “Whilst this small improvement is welcome it is still shocking that around 30 per cent of main roads in Scotland are in need of repair.”
A Scottish Government spokesman said the government was “committed to the largest road investment programme that Scotland has ever seen”, citing projects including the dualling of the A9 and the Queensferry Crossing. He said: “We fully recognise the importance of a safe and reliable trunk road network and the budget for maintenance for the roads we look after has increased by around £65 million to £433m in 2018/2019.
“A recent Audit Scotland report found 87 per cent of trunk roads are in an acceptable condition. In times of financial constraint we are making significant efforts to maximise every penny that is spent on maintenance and our Road Asset Management Plan sets out how we prioritise maintenance.”

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Many residents remain unconvinced a £5million investment in repairing the roads in Lincolnshire is making any significant improvement for those travelling around the Skegness area.
Ninety thousand potholes were repaired across the county last year, according to Coun Richard Davies, Portfolio Holder Highways, Transport and ICT in his annual report.
Coun Davies said it had been a busy year in which the highways team carried out 34,000 jobs, including about 4,000 emergency repairs, around 97% of which were done within 24 hours.
He said: “Our maintenance work included a £5m year-long pothole patching programme, which eliminated some of the worst potholes across Lincolnshire and prepared some roads for future surface dressing.”
The Standard took to social media to ask readers if they had noticed an improvement in the roads.
Reader Steve Lawrence commented that Lincolnshire County Council had got it wrong, thinking using chippings ‘was a cheap way of re-surfacing the roads’.
He said: “What they failed to see was the long term damage this would do to the structure of the road.
“The old surface is just as damaged, and the damage spreads, the surface breaks up, and you end up with all the roads looking like a WW1 battlefield.”
Eleanor Stuart commented: “Well, Spilsby was half a job – and not a very good job.
“The road going into Spilsby where the deli is and the Nelson Butt looks like a quarry.
“Where you (Lincolnshire County Council) tarmac the High Street, that corner floods for England and spreads into the Butter Cross car park. So yeah you all praise yourselves job well done. Just yet to see the job.”
In his report, Coun Davies outlined work that had been done to make other transport more attractive and ease congestion. This included continued work on the £5.7m Go Skegness project, bringing the area improved bus lanes, bus stops and pedestrian crossings, along with new cycle routes and footways.
Coun Davies added the winter presented its own challenges for the team. He said: “Our team of 43 gritters were out battling the bad weather day and night, recently covering a distance equivalent to a round trip to the South Pole in just four days.”
He said 2018 promises to be equally busy.
“We will again be repairing tens of thousands of potholes across the county, and have some exciting projects lined up,” he said.
“Other plans include the £2m congestion-busting improvements planned for Lincoln’s busy Wragby Road junctions, which are due to start in February.”
l Keep up-to-date by visiting www.lincolnshire.gov.uk/roadworks.


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Question: The Latest: Moon says North Korea crisis must end peacefully

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U.S. Joint Chiefs Chairman Gen. Joseph Dunford, left, talks with South Korean Defense Minister Song Young-moo during their meeting at the Defense Ministry in Seoul, South Korea, Monday, Aug. 14, 2017. Pool Photo via AP Kim Hong-Ji

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The US are preparing military options in the event of a North Korean attack
US Joint Chiefs of Staff Joseph Dunford said that pursuing diplomacy and economic sanctions remain the US's top priority, but the unpredictable nature of North Korea means military options must be ready for the potential outbreak of war.
Dunford made the comments during a discussion with South Korean president Moon Jae-in during a meeting to discuss the recent soaring tensions between Pyongyang and Washington.
Mr Moon urged the US not to allow the situation to deteriorate to a point where war is inevitable.
The South Korean leader, who has only been in office since May, said: "There must be no more war on the Korean Peninsula. Whatever ups and downs we face, the North Korean nuclear situation must be resolved peacefully.


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Question: This Exercise Pill Could Deliver All the Benefits of Working Out Without All the Effort

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Halfpoint/fizkes/ShutterstockEveryone knows regular exercise is essential, but not everyone can pull that off. For people with painful joints or limiting disabilities, being able to hit the gym, the jogging track, or even a home treadmill may be out of the question. But thanks to Salk Institute scientists, there may be a loophole—a pill that delivers all of exercise’s benefits, no workouts necessary.
A new study, published in Cell Metabolism, builds on earlier work revealing that running triggers a specific gene pathway known as PPARD. The Salk Institute scientists chemically activated PPARD in sedentary mice, and discovered they could bring about many of the beneficial effects of exercise in those mice—including increased fat burning and stamina—without a lick of activity. The mice got the drug over a period of eight weeks, and by the end, they could run on a treadmill for 70 percent longer (about 100 more minutes) than sedentary mice who didn’t get the drug, the researchers discovered.
“We previously activated the pathway in mice through genetic engineering,” explained senior author Ronald Evans, a Howard Hughes Medical Institute investigator, “and discovered that doing so turned the animals into long-distance runners, and they gained many of the health benefits of exercise such as better responsiveness to insulin and greater resistance to weight gain, and had many other markers of good health.” However, the mice still had to be active to gain all the benefits. In the new study, the mice got a higher dose of a chemical compound (called GW1516) that activates PPARD, and they got the compound for twice as long.
“Exercise activates PPARD, but we’re showing that you can do the same thing without mechanical training. It means you can improve endurance to the equivalent level as someone in training, without all of the physical effort,” says Weiwei Fan, a Salk research associate and the paper’s first author, in a press release from Science Daily.
“The drug will provide the most benefit for people who are physically unable to exercise due to other health conditions, like having COPD, being elderly, or wheelchair-bound,” said Michael Downes, a Salk senior scientist and co-senior author of the paper. “We realize athletes may want to take this drug for a competitive advantage, but it’s really meant for people who simply don’t have the option of exercising.” Human testing is next, which means a pill for the people who need it is still a few years away. In the meantime, you can find plenty of exercise loopholes if you know where to look.

These Exercises Could Keep Your Knees From Injury
We Used To Hate These Foods When We Were Kids, But Now We Love Them


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Question: Your private parts as poster art? In Sweden, having a wee bit of fun with men's proclivity to overshare

An unspecified portion of the proceeds will be donated to the United Nation’s campaign for gender equality, HeForShe, the website says. A limited-edition series of prints will feature famous “people in positions of power” who serve as a “reminder that there’s still a long way to go to stop sexual harassment.”

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So filthy we’ll need a clean-up on aisle five. In what appears to be the latest viral craze taking the web by storm, some young people are apparently flashing their private parts in public places and subsequently posting photos and videos of this lewdness on social media. The horror!
We’ve recently covered trends that ranged from amusing to borderline dangerous. But this one moves the dial to the latter, and then points down south.
Since no other place seems to get these kids going, the chosen location for this shtick happens to be the home of sausages, bottled beverages, and phallic-shaped produce. Hence, the trend was aptly named the #SupermarketFlash.
Take a look at how bad it’s gotten:
Welp. That’s one way to take your mind off those student loans.
Nothing screams empowerment like unsolicited public nudity.
We just wanna know what flavors those are. Looks good.
Now, don’t even argue with the “Oh, did you never do stupid sh*t when you were young?” line. Please. This generation grew up with a smartphone instead of a rattle in their hands; they know very well what they’re doing and that the Internet always remembers.
And if some reports are to be believed, significant others seem to be in on it. So don’t even pivot to a sexist narrative because we’re not absolving the boyfriends for this either.
Here’s a silver lining: this whole thing seems quite poetic. In the true spirit of variety that supermarkets espouse, these ladies serve as shining examples that there are billions of potential partners to settle for, employees to hire, and people we’d like to associate ourselves with.
Thanks for narrowing down our choices, girls.
Via Daily Star


Question: Ancient wrestling offers a future for some in modern India

Wearing nothing but loincloths, a group of boys warm up by climbing sturdy ropes that take them high into the trees. One teenager walks around the wrestling pit swirling incense, blessing the arena and preparing it for battle.
On this November evening, as the dusk thickens and the bugs venture out, a couple of dozen young devotees of kushti, the ancient Indian style of wrestling, have gathered to face off. They range in age from 10 to 16. The earth in the pit has been prepared as it has been for centuries, turned over and mixed with sawdust, turmeric and ghee, or clarified butter. It’s mildly fragrant and soft to the touch, making it easier on the wrestlers’ skin.
These devotees, or pehelwans, have made a commitment that extends beyond the hours they spend practicing each morning and evening. They live an ascetic lifestyle, eating specific foods like almond milkshakes and chapattis slathered with ghee. They don’t eat meat and refrain from smoking, drinking and dating.
The sport, thought to be 2,000 years old, is mentioned in ancient Hindu texts and depicted in temple carvings. Although women wrestlers have made strides recently in India, the vast majority of participants are men.
But like many traditions in a country that’s rapidly modernizing, kushti wrestling faces the threat of being left behind. It remains popular in states like Haryana, where these pehelwans are training. For many poor families, wrestling provides a glimmer of hope. Those who succeed can earn money, respect in their communities and even particular jobs. They’re often employed by the police force or India’s railways.
Fifteen-year-old Ankur Bharadwaj says it’s his dream to win an Olympic medal, like his idol Sushil Kumar, who has won two Olympic medals for India in freestyle wrestling. Bharadwag says he gets up at 4 a.m. and jogs to the wrestling pit before going to school.
“Hard work makes a man perfect,” he says. “That’s why we are practicing so regularly. There are no breaks if you want to be a wrestler.”
Inside the pit, Bharadwaj and the other wrestlers rub their hands with the earth and toss it over their bodies. Under the watchful eye of their coach, they lock arms with their opponents, lunging for their legs as they try to flip them onto their backs and into submission.
The boys aspire to be accepted into an akhada, a kind of wrestling hostel where they’re given a bed and can devote themselves to the sport fulltime if they choose. Akhadas come with shrines to the Hindu god Hanuman, who is seen as a kind of patron saint to the sport.
At dawn at a small akhada in the suburbs of Delhi, a man circles the arena dragging a thick piece of wood to smooth the earth. Another crushes almonds with a large mortar and pestle. A poster on the gate advertises a local wrestling bout with a first-place prize of about $3,000. The gate swings open and a cow noses its way inside, breaking into a trot when the wrestlers try to shoo it away.
Coach Hemand Kumar, 35, says wrestling has always been his passion. Even before he started at age 10, he would get up before dawn and watch his father wrestle. The boys who take it up are saved from “the nonsense” of the streets, he says. But he worries about the sport’s future in a country with a rapidly rising middle class.
“The rich kids, they don’t want to do it,” he says. “Those people who don’t have the money, they’re interested. But they don’t have the resources.”
Jai Prakash, a former Olympic wrestler who is president of the Delhi Amateur Wrestling Association, says it’s getting more difficult to find the land needed to set up new akhadas. And unlike the nation’s most popular sport of cricket, he says, it’s tough to find sponsors for kushti.
“Wrestling bouts in villages used to be like the festival season, with a joyous mood and crowds celebrating victories of their favorite wrestlers,” he says.
Still, he’s upbeat about the future of the sport, which is also known as pehlwani. He says wrestling authorities want to make kushti a part of some international wrestling competitions, something he hopes might begin next year.
At the renowned Guru Hanuman Akhara in Delhi there are about 25 resident pehelwans, most of them hulking men in their 20s and early 30s. Some train with giant clubs that they swing behind their backs. Others grab a rope that’s threaded through a pulley and haul into the air a bucket that’s filled with concrete.
Sitting in a chair watching the men practice is Naveen Mor, who has won a number of international wrestling fixtures, including a gold medal at the 2011 World Police and Fire Games in New York. He says his wrestling prowess helped him land a job with the Haryana state police, where he works as an inspector.
Like many Indian wrestlers, Mor started in the pit and later became proficient wrestling on a mat, which provides the standard arena for most international bouts.
He says his first love remains the pit, where bouts can sometimes last an hour until somebody finally gives up.
As he cuts back on competitions and does more coaching, Mor says he still follows the strict dietary rules of kushti, although he is more relaxed about other rules and has recently gotten married.
He says he doesn’t regret dedicating his youth to the sport.
“No working. No shopping,” he says with a grin. “Only wrestling, wrestling, wrestling. My life is wrestling. I love wrestling.”
___
Associated Press writer Ashok Sharma in New Delhi contributed to this report.

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Here is how hard it is to buy a gun in some of the biggest countries around the world.


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Question: BRIEF-Mylan provides update on Meridian Medical Technologies', expands voluntary worldwide recall of epipen auto-injector

March 31 Mylan Nv:
* Mylan provides update on meridian medical technologies', a Pfizer company, expanded voluntary worldwide recall of epipen® auto-injector
* Mylan - recall is being conducted as result of receipt of 2 previously disclosed reports of failure to activate device due to potential defect in supplier component
* Mylan NV - expanded voluntary recall is being initiated in U.S. And also will extend to additional markets in Europe, Asia, North and South America.
* Mylan NV - recall is being expanded to include additional lots as a precautionary measure
* Mylan NV says recall impacts 0.3 mg and 0.15 mg strengths of epipen auto-injector
* Mylan NV- none of recalled lots include authorized generic for epipen auto-injector, which is also manufactured by meridian medical technologies Source text for Eikon: Further company coverage:

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April 5 Jazz Pharmaceuticals Plc
* Jazz Pharmaceuticals reaches settlement with Hikma Pharmaceuticals related to Xyrem patent litigation
* Jazz pharmaceuticals - initial term of AG arrangement is six months, Hikma has option to continue sale of AG product for up to a total of five years
* Jazz pharmaceuticals- in connection with settlement, co granted Hikma and its unit right to sell authorized generic version of Xyrem in U.S. under Xyrem NDA
* Jazz pharmaceuticals plc - specific financial and other terms related to ag product are confidential
* Jazz Pharmaceuticals Plc - Hikma has been granted a license to sell its generic sodium Oxybate product under its ANDA at end of AG term
* Jazz Pharmaceuticals - co to receive meaningful royalty on net sales of AG product,with royalty rate increasing during initial AG term based on ag sales
* Jazz Pharmaceuticals - Jazz to be paid for supply of AG product, to be reimbursed for portion of service costs associated with operation of Xyrem REMS
* Jazz Pharmaceuticals- Jazz will also be reimbursed for a portion of service costs associated with distribution of AG Source text for Eikon: Further company coverage:


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Question: Big Brother viewers unimpressed to see Nicola McLean back in the house

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Big Brother viewers said they were unimpressed to see Nicola McLean back in the house after she ruffled feathers during the celebrity version of the show.
Model Nicola, 35, was at the centre of plenty of bust-ups and was branded “a bully” by her housemates Jedward when she was on the Channel 5 programme earlier this year.
The star has now returned to the house alongside Marnie Simpson and Gemma Collins as part of a task in the non-celebrity series – leaving viewers rather annoyed.
Seriously! Wtf is Nicola McLean doing on #BBUK AGAIN! I'm gonna have to turn off, ruined my summer! — ♡♥♡♥laura young♡♥♡♥ (@skuewhip) June 14, 2017
Omg I can't believe #BBUK are inflicting Nicola McLean on the viewing public yet again. 😤 — -- (@cluckingduck70) June 14, 2017
Others commented on the fact Nicola – who also appeared on the show in 2012 – has had so many stays in the house.
Nicola McClean should be charged rent the amount of time she's spent in the house #bbuk @bbuk — James Wildish (@jameswildish) June 14, 2017
I'm sure Nicola McLean just makes no plans whenever big brother is going to be on, how many series has she been on now?! 😂😂 #BBUK — Louise ☺ (@louiseee_96) June 14, 2017
There was also disappointment that Nicola’s sparring partner from the last series, How Clean Is Your House? star Kim Woodburn, has not entered the house.
Wish they sent in Kim she would have slayed in that house! #BBUK — Michael Teacy (@megamouth_88) June 14, 2017
And many thought a Nicola/Kim reunion would have provided some fireworks.
One viewer pondered: “Imagine a #gogglebox special tonight around Kim Woodburns, when she sees Nicola in the house.”
“I would love so much if Kim Woodburn walked in and to see Nicola’s face would make my day,” said another.
As part of this week’s shopping task, the housemates will have to cater to the whims and diva demands of their VIP guests.

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Jess Impiazzi has finished in fourth place on this year's Celebrity Big Brother .
The former Ex on the Beach star left Shane Lynch , Ann Widdecombe and Shane Jenek to fight for the crown.
The brunette beauty, 28, left the famous house after ballet dancer Wayne Sleep , who finished in fifth place.
Fans were gutted to see her go.
One said: "Absolutely loved jess wanted her in the top 3 but she’s done so well"
"Jess was my winner," another commened.
(Image: Credit: Lia Toby/WENN)
(Image: Credit: Lia Toby/WENN)
As she chatted with host Emma Willis, Jess said she didn't expect to last so long in the house.
The reality babe revealed that she had to borrow her housemates' belongings because she ran out of face wipes and other toiletries.
Emma also told Jess that she was never nominated by any of her other housemates.
She said: "Flabbergasted! It's all so unreal to walk out and then people are all cheering at you. It is such a wonderful thing inside your tummy.
"It never really went through my mind [winning]. I knew I felt I was friends with everyone. Amanda is my idol. Ann would let me speak about some things, I thought be struck down as a stupid little girl. She never made me feel like that. She would let me speak and I would learn. And Maggie was like my mum in the house. I met some people that will be cherished forever. That experience will never got lost ever."
She added: "I do my step dad's head in in the house so I thought for sure I would have annoyed someone."
Jess said she's really going to miss the house.
(Image: Credit: Lia Toby/WENN)
(Image: Credit: Lia Toby/WENN)
She said: "I was looking around today and I thought, 'I'm really going to miss this place'."
The 2018 series has been an epic on this year - but only one celebrity can be crowned the winner.
Transgender newsreader India Willoughby was the first contestant to be evicted, followed by journalist Rachel Johnson and the lovely Maggie Oliver being booted out in a double eviction. John Barnes became the first male evictee of CBB 2018 in a shocking backdoor eviction, shortly followed by Ginuwine in week three. A shock triple eviction saw Andrew Brady , Jonny Mitchell and Dapper Laughs evicted last week.
Shane Jenek , Shane Lynch , Ann Widdecombe , Jess Impiazzi and Wayne Sleep were confirmed finalists after a triple eviction on Tuesday night saw Amanda Barrie , Ashley James and Malika Haqq leave the house.


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Question: Finally!! American Rapper, Meek Mill Has Been Released From Prison

After being incarcerated since November 2017 for violating his probation, the Supreme Court has granted Meek Mill bail.
In a statement to Billboard, Meek said the following:
“I’d like to thank God, my family, my friends, my attorneys, my team at Roc Nation including JAY-Z, Desiree Perez, my good friend Michael Rubin, my fans, The Pennsylvania Supreme Court and all my public advocates for their love, support and encouragement during this difficult time,” began Meek. “While the past five months have been a nightmare, the prayers, visits, calls, letters and rallies have helped me stay positive. To the Philadelphia District Attorney’s office, I’m grateful for your commitment to justice — not only for my case, but for others that have been wrongfully jailed due to police misconduct,” he continued. “Although I’m blessed to have the resources to fight this unjust situation, I understand that many people of color across the country don’t have that luxury and I plan to use my platform to shine a light on those issues. In the meantime, I plan to work closely with my legal team to overturn this unwarranted conviction and look forward to reuniting with my family and resuming my music career.”
Philadelphia 76ers co-owner Michael Rubin posted a picture on Instagram celebrating Meek’s release from prison.
He wrote:-
“@meekmill is FREE!!! Just left visiting Meek with @kevinhart4real and I’m on the way back to pick him up as we speak! #MeekisFree #GoSixers”.
Last week, Meek Mill told CNN’s Don Lemon that he was optimistic that he was going to get out of jail sooner than later. “I don’t really try to get my hopes up from that court room right there”.
Meek said:-
“I feel like I will be free one day. I think I’ll be able to get my chance pretty soon. My time coming.”
See what Rubin posted below:-

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Diane Kruger and Norman Reedus Hit the Beach in Costa Rica (Us Weekly)
Tamra’s Daughter To Fire Cease & Desist Letter After Judge Continues To Slam Her (RadarOnline)
Catelynn Lowell & Tyler Baltierra Welcome A New Baby Into Their Family (OK! Magazine)
Willie Nelson Stage Shocker As Star Rushed To Hospital (National Enquirer)


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Question: Ravens Williams Fends Off Potentially Dangerous Eye Disease

OWINGS MILLS, Md. (AP) — Now that he can see clearly again, Baltimore Ravens defensive tackle Brandon Williams is ready to resume his lucrative NFL career.
Williams has an eye disease called keratoconus, a degenerative disorder which warps the corneas and can potentially cause blindness if left untreated.
“It started to hinder my seeing the board when we went over plays, so I had to get it fixed,” Williams said. “Once it starts messing with your craft, your career, you definitely have to put your attention on that before you do anything else.”
The condition is rare, and there is no cure. But it can be controlled by surgery.
“I was scared,” Williams acknowledged, “but also relieved that there was a treatment out there that could help me.”
The procedure is called cross-linking, which limits the progression of the disease by strengthening the corneas. Williams had surgery on his more troublesome left eye before the 2017 season and had the right eye corrected earlier this month.
And now, the 340-pounder is eager to do his part to help the Ravens get back into the playoffs after a three-year absence.
“I can do everything I used to do,” Williams declared. “Nothing is stopping me.”
That’s good news for the Ravens, who gave Williams a five-year, $52.5 million contract last year. Selected out of Missouri Southern State in the third round of the 2013 draft, the 29-year-old has been a vital cog in a Baltimore defense built first to stop the run.
Williams missed four games with a foot injury last year. The Ravens went 1-3 without him and 8-4 when he was in the lineup.
“He’s the main piece for our defense,” Baltimore coach John Harbaugh said.
Rajesh K. Rajpal, M.D., founder of See Clearly Vision Group in Virginia and an expert on laser eye surgery, performed both operations on Williams’ eyes.
“It almost always affects both eyes — 98 to 99 percent of the time — but usually one eye will be more severe,” Rajpal said. “Now that both eyes are done, Brandon should be fine. But we will continue to monitor him to make sure it doesn’t get worse.”
Williams wears contact lenses to aid his vision, but removes them on game days.
“In his case, the lenses he’s using allow him to function well enough in day-to-day activities,” Rajpal said. “During the football season, he plays without the lens because he doesn’t want to take a chance of getting something beneath the lens and damaging his eye. That’s OK, because he’s doing things up close and a lot of it is about feel.”
Rajpal added: “A baseball pitcher or a batter, it would be really tough for them to function without the contact lenses if they have this condition.”
St. Louis Cardinals outfielder Tommy Pham has undergone cross-linking and wears contact lenses on the field.
When Williams first experienced blurry vision, he figured he needed LASIK surgery. But Rajpal says LASIK would actually further thin the cornea.
“When we’re doing the testing for LASIK, we do corneal topography, which maps the corneal curvature,” Rajpal said. “If keratoconus is significant enough, we offer the cross-linking.”
If left untreated, the disease can be dangerous.
“Then we have to a corneal transplant,” Rajpal said. “Fortunately, the vast majority don’t completely lose their vision.”
Williams nevertheless knows he avoided a potentially life-changing situation.
“I am thankful for having my sight,” he said. Then, with a chuckle, he added, “I don’t have to be blind, so that’s a plus.”
Follow @CBSBaltimore on Twitter and like WJZ-TV | CBS Baltimore on Facebook
(© Copyright 2018 The Associated Press. All Rights Reserved. This material may not be published, broadcast, rewritten or redistributed.)

Good morning, here are our early stories:
-- U.K. Prime Minister Calls For Early Election.
-- In Japan, Pence Talks Trade And North Korea's Threat To The Region.
-- In The Rockies, Climate Change Spells Trouble For Cutthroat Trout.
And here are more early headlines:
Blanket Primary Today for Georgia Congressional Seat. (FiveThirtyEight)
U.N. Says "Staggering" Number Of People Fleeing Mosul. (UN News Centre)
Hollywood Writers Will Vote On Possible Walkout. (New York Times)
Boeing Laying Off Hundreds Of Engineers, Mechanics. (USA Today)
Suspect In Deadly Washington State Mall Shooting Kills Self. (UPI)
All 4 NHL Playoff Games Went Into Overtime Last Night. (AP)
NASA Puts 360 Degree Camera Aboard Rocket For Today's Launch. (PBS)
Sweden's 'Failure' Museum Highlights Commercial Flops. (Daily Mail)


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Question: Federal agents raid portable toilet company one week after executive was sent to prison

As many as two dozen FBI agents descended on the offices of Diamond Environmental Services in San Marcos early Wednesday morning, apparently searching for proof that the company skirted clean-air rules.
The early morning raid came just seven days after owner Arie Eric De John was sentenced to five months in federal prison for illegally dumping waste from the company’s portable toilets into city sewer systems across southern California.
De Jong, who must report to federal prison on or before July 6, could not be reached for comment. Knut Johnson, De Jong’s criminal defense attorney, said the FBI was executing a search warrant issued in an unrelated air-pollution investigation.
“In this case, they’re just starting an investigation,” Johnson said. “We don’t know what all the facts are but I do believe within the last few weeks (Diamond) had their trucks inspected by an independent inspector and I think they are all in compliance.”
Chief Operating Officer Warren Van Dam, who pleaded guilty and received five years probation in the earlier federal case, declined to discuss the FBI when reached by telephone.
“I have no comment,” he said before ending the call.
According to witnesses, FBI agents turned up at the East Mission Avenue headquarters of Diamond Environmental Services as early as 6:30 a.m. and began their search. Officers from the California Highway Patrol contributed to the effort.
They carted off boxes of paperwork, computers and other electronic goods. They also interviewed employees, especially truck drivers, about company practices that may violate U.S. Environmental Protection Agency standards.
“They interviewed all of the drivers, then they sent us home,” said one employee, who did not want to be named due to fear he might lose his job.
The employee said investigators were especially interested in whether trucks had been mechanically altered. “They said they were working with the EPA,” the employee said. “They asked me what it was like working for them, if I had seen anything and what I knew about the DPFs.”
DPFs, or diesel particulate filters, are devices that are designed to remove soot from the exhaust gases emitted from diesel engines. Under state and federal clean-air rules, trucks are supposed to be equipped with the devices to reduce air pollution.
Federal officials declined to comment on the raid.
The FBI raid came just seven days after De Jong and Van Dam faced criminal sentencing in U.S. District Court on an unrelated case that accused them of illegally dumping portable-toilet waste into municipal sewer systems across southern California.
According to federal prosecutors overseeing the recent criminal case, De Jong and Van Dam conspired to avoid discharge permit fees and save travel time to and from plants that treat the waste by pumping the sludge into city sewer systems illegally.
The scheme went on for at least four years, and saved the company at least $2 million, prosecutors and court documents said.
Both De Jong and Van Dam pleaded guilty last year. A third executive was convicted of perjury for lying to a grand jury about the company disposal practices. The company agreed to pay $6 million or more in fines, restitution and illegal profits.
In addition to the prison and probation terms, the company and its senior executives agreed to pay millions of dollars in fines, restitution and forfeited profits.
Johnson said his clients works hard to meet all environmental regulations.
“They are extremely concerned about the environment,” the criminal defense attorney said of his clients. “Diamond Environmental Services does a fantastic job in a very dirty business in keeping the environment clean.”
It is not clear how the new criminal investigation might affect the sentences handed down last week. One condition of the probation sentences received by De Jong and Van Dam was for the defendants to obey all laws.
CAPTION As a sexual-misconduct case deepens within the San Diego Sheriff’s Department -- a 10th women has come forward with a legal claim against the county -- three alleged victims are raising questions about why the accused lawman has not been arrested. As a sexual-misconduct case deepens within the San Diego Sheriff’s Department -- a 10th women has come forward with a legal claim against the county -- three alleged victims are raising questions about why the accused lawman has not been arrested. CAPTION The City of San Diego helped build a $2-million public restroom, after years of rejecting calls for toilets to address unsanitary conditions downtown. The City of San Diego helped build a $2-million public restroom, after years of rejecting calls for toilets to address unsanitary conditions downtown.
jeff.mcdonald@sduniontribune.com (619) 293-1708 @sdutMcDonald

LONDON (AP) – Big Ben will fall silent next week in London as a major restoration project gets underway.
The bongs of the iconic bell will be stopped on August 21 to protect workers during a 4 year $38 million conservation project that includes repair of the Queen Elizabeth Tower, which houses Big Ben and its clock.
Steve Jaggs, keeper of the Great Clock, said Monday that the mechanism will be dismantled piece by piece and its four dials will be cleaned and repaired.
Big Ben has been stopped several times since it first sounded in 1859, but the current restoration project will mark the longest period of silence for the bell. It will still sound on big occasions, such as Remembrance Sunday.
It will still sound on big occasions, such as Remembrance Sunday.
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Question: Dear Jacqueline Fernandez, we are fans of your moves

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Jacqueline Fernandez will also show off her moves in her upcoming film, A Gentleman Sundar Susheel Risky. Jacqueline Fernandez will also show off her moves in her upcoming film, A Gentleman Sundar Susheel Risky.
As if the pole dance in her upcoming film A Gentleman was not enough, Jacqueline Fernandez has shared another seductive video. But before you get ideas, we have to tell you that this video is of her dance practice on what we are guessing is her upcoming number Bandook Meri Laila from the Raj Nidimoru and DK Krishna directorial.
The actor shared the video on Twitter and announced a workshop. Along with the video, she wrote, “Had the pleasure of working with this mad man @bensoyza so excited for his workshop tomo along with my fav @karishmachavan be there guys it’s gonna be awesome.”
Over the years, Jacqueline has not only been grabbing eyeballs but also improving as an actor. If you compare her films, you would know that this sexy lady has come a long way.
Meanwhile, we just cannot take our eyes off how she sways. How can we not mention her pole dance! Jacky instantly made news for her pole dance sequence in the song Chandralekha from A Gentleman. The actor described it has an “awesome experience.”
Recently, amid the busy promotional schedule, Jacqueline went on a short trip to Tokyo to celebrate her birthday. Going by her updates, we can safely say that she had a gala time.
Up next in Jacky’s career is her next big film this year, Judwaa 2, which will also star Taapsee Pannu and Varun Dhawan.
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Priyanka Chopra’s beach selfie and Jacqueline Fernandez’s sport picture is just perfect. Priyanka Chopra’s beach selfie and Jacqueline Fernandez’s sport picture is just perfect.
Bollywood has welcomed New Year in full swing. While a lot of us cannot get over the Kareena Kapoor Khan- Saif Ali Khan’s house party on New Year’s eve, Priyanka Chopra, Jacqueline Fernandez, Sonam Kapoor and Hrithik Roshan have started off 2017 with breathtaking and trend-setting pictures. Priyanka shared a picture on her Instagram in which she is sunbathing on a beach. Her beach look is drool-worthy.
Along with the picture, she wrote a caption which read, “Past and Present I know well; each is a friend and sometimes an enemy to me. But it is the quiet, beckoning Future, an absolute stranger, with whom I have fallen madly in love. -Richelle E. Goodrich. 1st selfie on the last day of vacayyyy.. have a wonderful year everyone… NYC bound….”
Well, this desi girl is prepping up for her Hollywood debut Baywatch, which also stars Dwayne Johnson. Apart from that, the actor will be presenting Golden Globe Awards this year and has yet again been nominated for People’s Choice Awards 2017 for her television series Quantico season 2, in which Priyanka plays an FBI agent. But along with being busy with her overseas projects, she has also been spotted extensively promoting her Punjabi production film, Sarvann. She is likely to announce her Bollywood projects soon too.
Next up is the picture of Jacqueline Fernandez. Standing in the middle of snow-capped mountains, this picture of Jacqueline for sure makes us want to pack our bags and leave for vacations. In fact, the actor has some short videos, which totally make us fall in love with this cute actor.
Oh, by the way, this actor has her skiing game strong. Jacqueline spent her Christmas and New Years with her family at Courchevel, which is a French Alps ski resort.
The actor, who had an amazing 2016, has wrapped up the shoot of her next flick with Sidharth Malhotra. The film, called Reload, is a sequel to Bang Bang that starred Hrithik Roshan and Katrina Kaif.
Talking about skiing, how can one miss Hrithik Roshan’s picture with his sons. This adorable picture tags Hrithik as the best father one could see. The actor often spends his holidays with his sons Hrehaan and Hridhaan and every time, he ensures they experience a new adventure. Even on New Year, the actor took his children on an adventure spree.
Along with this beautiful picture, the actor wrote, “Another year. Another chance to make life even brighter and better. Work hard, play harder. Envision it, manifest it. Let’s make the most of it. A Happy New Year to all of you from me and my boys!”
The actor has a big release, Kaabil this year. Soon, he would start promoting his film, which clashes with Shah Rukh Khan’s Raees.
More from the world of Entertainment:
Last but not the least is Sonam Kapoor’s perfect picture with her bae Anand Ahuja. The actor, who is rumoured to be dating her best friend Anand, is spending some quality time in London and their first picture together of 2017 is extremely cute, setting friendship goals for the year.
Well, that’s for sure the kind of crazy bond we all have experienced. Don’t they look adorable here?
Also read | Mariah Carey’s New Year’s show is latest mishap in the spotlight, see pics
The actor won hearts for her performance in Neerja. Now, she will soon start shooting for her next films, Veerey Di Wedding and Battle for Bittora.
© The Indian Express Online Media Pvt Ltd


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Question: Man facing jail after a child put ecstasy in their mouth

A seven-year-old boy was moments from “absolutely catastrophic consequences” when he popped a drug dealer’s misplaced ecstasy into his mouth thinking it was a sweet - only to spit it out because it “didn’t taste nice”.
Dean Shaw was today (Wednesday) facing a lengthy jail term after his stash was found in potentially fatal circumstances.
A handful of the class A pills inadvertently ended up in a carrier bag containing an iPad at his home in Arbroath.
That was then taken away by a woman and put on her kitchen table.
Her son, who cannot be named for legal reasons, went to play with the iPad and found the stash - and popped one of the yellow, strawberry shaped tablets into his mouth.
But fortunately the youngster spat it out because “it didn’t taste nice”.
He went off to play before his mother then entered the kitchen and found the pills strewn across the table.
Fiscal depute Vicki Bell told Dundee Sheriff Court: “She thought they were sweets and noted there were some left in the shopping bag.
“She asked the child about the sweets and he said they were not sweets as he had put one in his mouth and it didn’t taste nice so he spat it out.”
Knowing the bag had been in Shaw’s home she contacted him.
Miss Bell added: “He didn’t know why the tablets were there and stated they were ecstasy.
“The child was taken to Arbroath Minor Injuries Unit and observed but didn’t have any symptoms of ingesting the tablets.
“Police were contacted and the accused’s address was searched.”
Police found £3691 in cash, cocaine worth up to £9600 on the street and 28 ecstasy tablets worth £10 each.
The prosecutor added: “He told police he didn’t know how the tablets got in the bag.
“He said the only explanation was that he had had a party and when people left someone had put them there because they didn’t want to take them in to the street.”
Shaw, 27, of Arbroath, pleaded guilty on indictment to charges of being concerned in the supply of cocaine and possessing ecstasy on August 15 last year.
Shaw wiped away tears in the dock as defence solicitor John Hall said: “He profoundly and profusely apologises for this.
“It is not lost on him that there could have been absolutely catastrophic consequences.
“The boy came very close to suffering the ill effects.
“Had it not been for the apparently bad taste he could have suffered absolutely catastrophic consequences.
“He is fully aware that the likely outcome of this case will be a period of custody.”
Mr Hall added: “He has no previous convictions of any description.
“He is a self-employed jewellery designer.
“He previously produced reasonably sought after items of jewellery but has been unable to recently because of a cocaine addiction.
“He was supplying at a lesser level to four or five people who were well known to him.
“This was not bringing him in money - it was simply to allow him to feed his habit.”
Sheriff Lorna Drummond QC deferred sentence until next month for social work background reports and released Shaw on bail meantime.
She said: “It is a serious matter - I don’t have to remind you of that.
“Especially in combination with the other offence given the circumstances putting the child at risk.
“These are very serious matters and custody must be at the forefront of the court’s mind.”

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'I never screamed so much in my life': Woman horrified by what she finds in her luggage


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Question: Sheffield United: Wilder ready to utilise Blades squad strength

Sheffield United are poised to make changes to their starting 11 for tomorrow’s game against Bradford City.
But, after being crowned League One champions yesterday, manager Chris Wilder insisted his selections will be based on sporting needs rather than sentiment.
“We’ll have a little look,” he said. “We will try and utilise the squad over the weekend. There’s no romance or feelings involved.
“There are unique parts of the season, Christmas and Easter are two, when you have to look at the group and what’s best. You always put your best team out but you have to have half an eye on the schedule.”
Wilder’s willingness to reshuffle the options at his disposal - Billy Sharp and former City centre-forward James Hanson are among those rested in recent weeks - has enabled United to avoid unnecessary injuries during the second half of the campaign.
“It’s quite easy to pile your money into 11 or 13 players,” he added. “You hear people moan about having small squad but they choose to run with one. We feel we’ve got the right numbers and the right balance of everything.
“We’ve got a sign up on the wall in the office detailing the things we need to tick off; right -ooters, left-footers, characters and good technique.”
Meanwhile, City defender Tony McMahon has congratulated his former club on winning the title ahead of his return to Bramall Lane.
McMahon, who represented United between 2012 and 2014, said: “Credit to them, United have been the best team throughout the season.”
With City in fourth, McMahon added: “We’re in good form. Not many will want to play us in the play-offs. But we’ve got to finish the job off.”
For more news from Bramall Lane click here

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Aston Villa’s players have returned to Bodymoor Heath for pre-season training as preparations begin for a third assault on the Championship.
Villa’s first two cracks at promotion have ended unsuccessfully with the latest blow arriving in devastating fashion at Wembley in May.
Steve Bruce will be glad to return to Villa’s pristine training pitches and momentarily escape the frustrations of the transfer window.
A lot of those frustrations will need to be solved on the training ground this summer with Tony Xia unable to wave his cheque book around.
With that in mind, Bruce must use the next few days/weeks wisely.
Identify the kids
It’s our understanding that Bruce will find room in his first team for some of Villa’s most talented youngsters following cuts to the playing staff.
Callum O’Hare and Rushian Hepburn-Murphy made seven Championship appearances off the bench last season, but Bruce will have to use them more regularly next term.
O’Hare will miss pre-season through injury but Hepburn-Murphy is fit and raring to go following an injury-ravaged beginning to the 2017/18 campaign.
Bruce will take a closer look at the likes of Mitch Clark and Jake Doyle-Hayes to see if they can also make the jump.
Communication strategy
Steve Round’s exit hasn’t come as a great shock but what it has done is leave Bruce in a prickly predicament.
The manager’s two main allies in terms of transfers, Round and CEO Keith Wyness, are no longer at the club.
Wyness and Round acted as Bruce’s go-between to Xia. Bruce and Xia now need to form a clear path of communication, whether that’s done directly or through the owner’s personal assistant Rongtian He.
Take a look at Elphick
Replacing John Terry is a primary concern for Bruce this summer and Tommy Elphick appears to be the favourite for the role.
Former skipper Elphick played just three Championship matches last season before he was shipped out to Reading in January.
Reading are eager to sign Elphick permanently but Bruce wants another look at the centre-back who impressed with dominant displays against Middlesbrough and Bristol City over Christmas.
Elphick will want to be assured of his place in Villa’s first team before committing, though. The former Bournemouth defender is wary of wasting further time stagnating on the bench.
Bruce has previously sounded out German defender Robert Huth, but Elphick will be first to stake his claim to replace Terry.
Solving the McCormack riddle
Bruce isn’t Ross McCormack’s biggest fan, that much is obvious. But a club in Villa’s situation cannot afford to cast aside a £12million striker earning in excess of £40,000 per week.
The striker flourished during a stint on loan with Melbourne City last season and fired 14 goals in 17 matches - but Bruce had no interest in reintegrating him upon his return to the Second City in January.
With the club in the midst of a promotion battle at the time that was understandable, but Bruce can’t freeze him out forever.
A solution needs to be found this summer which is in Villa’s best interests. Does Bruce persevere with the forward and let bygones be bygones or does he find a way to get him off the books?
(Image: Neville Williams/Aston Villa FC via Getty Images)
Key meetings
Meetings with the club’s hierarchy won’t be Bruce’s only set of crunch talks this week. The Geordie needs to sit down with several key players and let them know where they stand.
Jack Grealish is expected to leave this summer and Bruce needs to find out where the Solihull-born playmaker sees his future so a resolution can be found quickly.
James Chester is another player whose future has been the subject of speculation. The Wales international is among Villa’s most saleable assets and Stoke City and Brighton are keeping tabs on him.


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Question: Hilary Duff back together with ex Matthew Koma?

Hilary Duff and music producer Matthew Koma have reportedly rekindled their relationship.
The Lizzie McGuire star began dating Matthew last year, shortly after her romance with her personal trainer Jason Walsh fizzled out in November, but she parted ways with the hitmaker in April.
She was seen embracing businessman Ely Sandvik in July, sparking rumours of a summer romance, but it now appears she has found love with Matthew again, according to E! News.
Hilary celebrated her 30th birthday on 28 September and Koma is featured in the pictures from her party. Matthew also posted a picture of the pair looking lovingly at each other on his Instagram page.
“#tBt (throwback Thursday) birthday girl,” he captioned the picture.
#tBt birthday girl A post shared by Matthew Koma (@matthewkoma) on Oct 5, 2017 at 3:23pm PDT
According to a source, the couple has been back together since his tour ended.
“Since Matt got back from tour, they’ve been seeing each other again,” a source told the website. “Him being gone on tour was the main reason things didn’t work out the first time around, so now that he’s back they picked up right where they left off.”
“He took her on a romantic dinner date for her birthday, bought her a guitar, and was at her 30th birthday party,” another source added. “Her friends and family really adore Matthew. Hilary also wants to get in the studio with Matthew and they have had a working relationship.”
Someone got me a guitar for my birthday. Time for some lessons.... pic.twitter.com/t9owSNNS9P — Hilary Duff (@HilaryDuff) September 29, 2017
Hilary and Matthew have not commented on the status of their relationship.
The singer and actress split from Mike Comrie, the father of her four-year-old son Luca, in 2014, after three years of marriage. They finalized their divorce in February, 2016, but remain close friends.

The Aussie model is expecting baby number two with her Snapchat founder hubby Evan Spiegel.


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Question: Turbulent Senate race now in hands of Alabama voters

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BIRMINGHAM, Ala. (AP) — Depending on who is making the case, Alabama’s special Senate election Tuesday is about either continuing the “Trump miracle” in Washington or allowing “decency” to prevail back home.
At the center is Roy Moore — “Judge Moore,” to his supporters. The 70-year-old Republican was twice ousted as state Supreme Court chief justice after flouting federal law, and now he’s attempting a political resurrection amid accusations of sexual misconduct with teenage girls when he was in his 30s.
In Moore’s path is Democrat Doug Jones, a 63-year-old former U.S. attorney best known for prosecuting two Ku Klux Klansmen who killed four black girls in a 1963 church bombing.
The winner will take the seat previously held by Attorney General Jeff Sessions. Republicans hold a narrow 52-48 Senate majority. A routine election in Republican-dominated Alabama wouldn’t be expected to alter that balance, because Alabamians haven’t sent a Democrat to the upper chamber of Congress since 1992. President Donald Trump notched a 28-point win here in 2016 and remains popular in the state.
But Moore’s baggage leaves the outcome enough in doubt that both Trump and his Democratic predecessor, Barack Obama, have weighed in with last-minute robocalls trying to sway voters.
The intensity also has spawned a steady stream of fake news stories that fill social media feeds of interested people in Alabama and beyond. An Associated Press analysis, in cooperation with Facebook, counted as many as 200 false or misleading reports heading into the weekend. One website claimed one of the women who have accused Moore of sexual misconduct had recanted. She did not. Meanwhile, Moore’s detractors took to social media to claim he had written in a 2011 textbook that women shouldn’t hold elected office. He didn’t.
In his final pitch before polls open, Jones called the choice a “crossroads” and asked that “decency” prevail.
“We’ve had this history in the past, going down the road that … has not been productive,” Jones said. “We’ve lagged behind in industry. We’ve lagged behind in education. We’ve lagged behind in health care. It’s time we take the road that’s going to get us on the path to progress.”
At his own election eve rally, Moore again denied all the allegations, calling them “disgusting” and offering voters a clear measure: “If you don’t believe in my character, don’t vote for me.” Earlier in the day, Moore cast himself as the victim. “It’s just been hard, a hard campaign,” he said.
For Alabama, the outcome could be defining.
Democrats and moderate Republicans see an opportunity to reject a politician who is already regular fodder for late-night television and enough of a curiosity that Chinese leader Xi Jinping paused a presidential meeting in Beijing recently to ask Trump through an interpreter, “Who is Roy Moore?”
Alabama’s senior senator, Richard Shelby, confirmed publicly that he wrote in a “distinguished Alabama Republican” rather than vote for Moore.
Many Republicans, however, see an opportunity to defend the state’s conservative, evangelical bent in the face of unfair liberal criticism while delivering another victory for Trump and sending an anti-establishment senator into a federal government that has been reflexively unpopular among Alabama majorities for generations.
Trump’s campaign architect and former White House adviser Steve Bannon told Moore supporters Monday evening that the race is a “national election” that will determine whether the “Trump miracle” continues. Moore says he is aligned with the president and he makes similar arguments to Trump, blasting “the elite” in the “swamp” of Washington, D.C.
For Jones to win, he must build an atypical coalition, maximizing turnout among African-American voters and white liberals who often don’t combine for more than 40 percent of the electorate, while coaxing votes from enough white Republicans who can’t pull the lever for Moore.
One of Jones’ celebrity backers framed the choice as being much less complicated.
“I love Alabama,” said Leeds native and former NBA basketball star Charles Barkley, “but at some point we’ve got to draw a line in the sand and say, ‘We’re not a bunch of damn idiots.’”
Polls open at 7 a.m. local time.

Democrat John Ossoff, left, faces off June 20 against Republican competitor Karen Handel, right, for Georgia’s 6th District congressional seat.
Roll Call political correspondent Simone Pathè explains how the most expensive House race in history, next week's contest to fill an open seat in suburban Atlanta, has already revealed plenty about the new congressional electoral landscape in the age of Trump.
Show Notes:


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Question: Athletes of the week: Top Bay Area performers

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South Bay/Peninsula
Simon Heck, Los Altos
Sport: Baseball
Position: Left field
Class: Senior
The 6-foot-7, Pomona College-bound standout had one heck of a Central Coast Section Division I championship game, going 3 for 3 with two doubles and three RBIs as 11th-seeded Los Altos completed its improbable run to the title with a 5-3 victory over top seed Bellarmine College Prep at Municipal Stadium in San Jose. Heck’s two-run double to left tied the score 2-2 in the second, and his run-scoring double well over the left fielder in the sixth padded the advantage to 5-3. Had a .455 batting average in the playoffs.
Jazlynn Shearer, Silver Creek
Sport: Track and field
Events: Jumps, hurdles
Class: Junior
Sprained her ankle in the long jump at the Central Coast Section championships and still finished second in 18 feet, 8 inches. Then won the 100 hurdles in 13.94 seconds, finished third in the triple jump in 40-3 1/4 and ran the lead leg on her school’s 4×100 relay team, which took second in 48.16. Qualified for state in all four events while helping Silver Creek win its first CCS girls team title since 1977.
East Bay
Cameron Reynolds, Clayton Valley Charter
Sport: Track and field
Events: 200, 400, 4×400 relay
Class: Junior
State leader in the 400 finished second in that event at the North Coast Section Meet of Champions in Berkeley, edged by Marin Catholic’s Max Glasser, but came back to win the 200 and anchor Clayton Valley’s victory in the 4×400 relay in 3 minutes, 15.87 seconds, a time that ranks fourth in the state. Won the 200 in in 21.58. In the 400, Reynolds ran in 47.56 — not quite as fast as his state-leading 47.09 — and Glasser won in 47.41.
Tierra Robinson-Jones, Bishop O’Dowd
Sport: Track and field
Events: 200, 400, 4×100 relay
Class: Senior
Broke an eight-year-old North Coast Section Meet of Champions record in the 400 with a personal-best time of 52.69 seconds, which ranks first in the state and fourth in the nation this season. Later, she won a third consecutive section title in the 200, breaking a meet record in that event as well, running in 23.56. That time that ranks second in the state. Also ran the second leg on O’Dowd’s winning 4×100 relay team, which ran in 47.17.
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To nominate candidates for Athlete of the Week, Highlight Reel and Movin’ On Up, email highschools@bayareanewsgroup.com by noon Monday.

Faces of Spring boys track 2018. In March, some of the sport's brightest stars from area high schools stopped by our studios for preseason portraits.


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Question: Halifax weatherman finds scorpion in his bananas

HALIFAX — A weatherman says he got more than he bargained for during a recent trip to a Costco in Halifax after finding a live scorpion in a bag of bananas.
Nathan Coleman, a reporter for The Weather Network, says he was unloading groceries when his 11-year-old daughter spotted something squirming in a plastic bag.
Coleman says he dismissed the rustling until his mother put the bananas away and noticed the barb-tailed insect.
He says he double-bagged the scorpion and drove to the Nova Scotia Museum of Natural History, where it has been jarred for observation.
Coleman says a warehouse manager has apologized to him and says Costco is looking into the incident, but he thinks the product should be pulled from the shelves in the interest of safety.
He says he’s hoping to find out whether the scorpion is venomous and how it was able to journey thousands of kilometres.

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Question: Netflix Signs ‘Scandal’ Creator Shonda Rhimes Away from ABC, as Battle for Talent Escalates

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Netflix Inc. has recruited prolific television producer Shonda Rhimes, the creator of ABC hits such as “Scandal” and “Grey’s Anatomy,” the clearest sign yet of an arms race for talent between new and old entertainment industry giants.
Under the terms of the multiyear exclusive agreement, Netflix said Ms. Rhimes, whose credits also include “How to Get Away with Murder,” would develop new shows for the streaming service. She will move her production company ShondaLand from its current base at Walt Disney Co.’s ABC Studios...

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Question: The Latest: 41 advance to finals of National Spelling Bee

The Latest on the Scripps National Spelling Bee (all times local):
6:05 p.m.
Forty-one spellers have advanced to the finals of the Scripps National Spelling Bee out of a field of 516, by far the biggest in the 93-year history of the competition.
The finalists were announced Wednesday after two days of onstage spelling during which nearly 200 spellers were eliminated for getting words wrong. Scores on a written spelling and vocabulary test determined who advanced to the finals.
There were no perfect scores on the test. Bee executive director Paige Kimble says, "We thought it was an easy test. We were wrong."
The top scorers were Shruthika Padhy, Aisha Randhawa and Karthik Nemmani.
Shruthika already came into the bee as one of the favorites, having finished in seventh place last year.
The past 13 champions and 18 of the last 22 have been Indian-American.
5:19 p.m.
With the Scripps National Spelling Bee extended to three days this year, longtime pronouncer Jacques Bailly finally needed some help.
Bailly's understudy for the past 16 years, the Rev. Brian Sietsema, filled in for him during portions of Wednesday's competition.
Sietsema is a Greek Orthodox priest from Michigan, as well as a former linguistics professor and lexicographer.
Bailly is the longtime public face of the bee. He says it was hard to take his first-ever break, but he knew it was necessary.
This year's bee nearly doubled in size because Scripps started a wild-card program that allowed kids who didn't win their regional bees to get to nationals. More than 500 spellers competed over two days of preliminary rounds. No more than 50 finalists were to be announced later Wednesday.

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Question: Cowboys Fan Uses Obituary to Declare ‘Dez Caught It’

An 86-year-old man in Wichita Falls used his obituary to let the world know that “Dez, did, in fact, catch the ball.”
Robert Clyde Drew, a loyal Cowboys fan, died Jan. 25 “mainly, we suspect, to prevent himself from having to watch the Patriots and Eagles in the Super Bowl,” his obituary said online for Dignity Memorial funeral home.
His funeral was held yesterday where his family’s wish was “in lieu of flowers, please do something nice for someone else.”
The obituary read:
In Memory of
Robert Clyde Drew
June 21, 1931 - January 25, 2018
Robert Clyde Drew, beloved husband, father, and Papa, drew his last breath January 25, 2018, mainly, we suspect, to prevent himself from having to watch the Patriots and Eagles in the Superbowl. A loyal Cowboys fan, he died peacefully with his daughter by his side, knowing full well that Dez, did, in fact, catch the ball.
Rob was born June 21, 1931 somewhere in Maine, though none of us are sure where exactly. He grew up on the east coast before making his home in Wichita Falls, Texas. He married his sweetie pie, Barbara, in 1971, and together, raised five beautiful children.
Rob was a stylish, yet, practical man. He dressed in the fashion of a Rat Pack member and amassed quite a collection of Fedoras, yet could often be found wearing the latest couture V-neck from The Fruit of the Loom. He was an expert on flag etiquette, played the piano and guitar, and could recite almost every line from any episode of Perry Mason or Bonanza. After so many visits to the Taco Bell with his granddaughter "Shorty," Rob developed quite a passion for their tacos. He was also a connoisseur of breakfast joints and a fanatical detailer of his automobiles.
In addition to his membership in the Elks Lodge, Rob was a Master Mason with Grand Lodge of Texas Freemasons, a member of the Maskat Shriner organization and a Knight with the Knights Templar Commandery No.59. Rob proudly served and retired from the United States Air Force as a Senior Master Sergeant. His days as a jet fighter mechanic served him well in his career at Longhorn Chevrolet. However, his greatest accomplishment may have been that one time when he beat pancreatic cancer; a feat not achieved by many.
Rob leaves behind a loving family in his wife, Barbara, his children, Lorie, Robert (& wife Debbie,) Deborah (& husband Danny, deceased,) Carla (& husband Jack,) Clark (& wife Judy,) and Keith (& wife Rebecca,) as well as grandchildren David, Chris, Jackie, Jason, Courtney, Aaron, Nick, Sabrina, Brittany aka "Shorty", and his sweet Brie, along with a bunch of great-grandkids.
Rob was the life of our party and will be deeply missed.
A graveside service is planned for Thursday February 1st, 2018 at 2pm, Crestview Memorial. In lieu of flowers, please do something nice for someone else.

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This is fantastic !!! Everyone wanted to be a Toys R’ Us kid right?
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Question: Wednesdays scores, updated schedule

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Division I
Tuesdays semifinals
No. 1 De La Salle 10, No. 4 Heritage 0 (5 inn.)
No. 2 Foothill 11, No. 14 Freedom 1 (5 inn.)
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Saturdays championship at St. Marys College in Moraga
No. 1 De La Salle (25-4) vs. No. 2 Foothill (23-5), 3:30 p.m.
Division II
Wednesdays semifinals
No. 1 Alameda 1, No. 4 Drake 0
No. 2 Maria Carrillo 5, No. 11 El Cerrito 4
Saturdays championship at Diablo Valley College
No. 2 Maria Carrillo (23-6) vs. No. 1 Alameda (26-2-1), 3:30 p.m.
Division III
Tuesdays semifinals
No. 9 San Marin 7, No. 5 Bishop ODowd 4
No. 2 Campolindo 12, No. 6 Kennedy-Fremont 3
Saturdays championship at St. Marys College in Moraga
No. 2 Campolindo (15-10) vs. No. 9 San Marin (16-11), noon
Division IV
Wednesdays semifinals
No. 4 Piedmont 11, No. 1 Middletown 8
No. 10 Saint Marys (15-11) vs. No. 6 Redwood Christian (19-7) at San Leandro Ball Park, 7 p.m.
Saturdays championship at Diablo Valley College
No. 4 Piedmont (19-9-1) vs. TBA, noon
Division V
Tuesdays semifinals
No. 5 Athenian 12, No. 1 St. Vincent de Paul 5
No. 2 Branson 3, No. 6 Berean Christian 1
Saturdays championship at Marin Catholic High
No. 2 Branson (16-10) vs. No. 5 Athenian (17-4), 1 p.m.
Division VI
Fridays championship
No. 2 San Francisco Waldorf (18-6) at No. 1 South Fork (17-10), 5 p.m.

The Knights shut out the Knights on Friday, Oct. 6.
Several high school games are on tap for Saturday so stay in the know on game outcomes with the Eyewitness Sports High School Football Scoreboard.


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Question: FAA Investigating After Harrison Ford Flies Over Jetliner Awaiting Takeoff

Noted aviator and actor Harrison Ford flew his private plane over a jet airliner on the ground at a Southern California airport Monday. It's not the first time the Star Wars and Indiana Jones star has had problems landing.
The 74-year-old Ford was instructed to land on a runway at Orange County's John Wayne Airport but mistakenly landed on a parallel taxiway, passing over a Boeing 737 carrying 110 passengers and six crew members.
On a recording, Ford asked air traffic controllers, "Was that airliner meant to be underneath me?" according to NBC News, which first reported the incident.
Federal Aviation Administration spokesman Ian Gregor said the pilot heard and read back the correct landing instructions, according to The Associated Press. Gregor did not confirm it was Ford who was piloting the plane, a single-engine Aviat Husky. The AP reports that he didn't say how close Ford's plane came to hitting the jet on the ground.
No one was injured and the jet, American Airlines Flight 1456, took off for Dallas shortly after without incident.
The FAA is now investigating, which "could result in a simple warning letter to a suspension of Ford's pilot's license," NBC reports.
Ford collects vintage planes and has been flying for decades. According to NPR's Russell Lewis, Ford is "a highly-skilled and highly-rated pilot. He's qualified to fly single and twin engine planes, sea planes, helicopters and he's also an instrument-rated pilot." In 2015, Ford said he owned "eight or nine various types of airplanes," according to NTSB documents posted on AirSafe.com.
Ford reported on a medical certificate application that he had logged at least 5,200 flight hours, according to the NTSB.
He was a 2008 honoree and received the Legends Aviation Legacy Award from Kiddie Hawk Air Academy, and subsequently had an award named after him.
Ford was seriously injured in March 2015 when he crash-landed a restored World War II-era trainer plane on a golf course near the Santa Monica Airport shortly after takeoff. A National Transportation Safety Board report found the crash was caused by a loose engine part.
In 2000, Ford's plane "departed" a runway in Lincoln, Neb., because of a gust of wind, according to AirSafe.com. He was flying a Beechcraft Bonanza which "sustained minor damage," though Ford and his passenger were not injured.
And in 1999 he crash-landed a helicopter during a training flight in Ventura County, near Los Angeles, according to the AP. "Although the helicopter rolled over on its left side, neither Ford or the instructor were injured," AirSafe.com notes.

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