safetensors license:apache-2.0 region:us
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# LAMAR
A Foundation **La**nguage **M**odel for RN**A** **R**egulation

This repository contains pre-trained and fine-tuned weights for RNA foundation language model **LAMAR**. LAMAR outperformed benchmark models in various RNA regulation tasks, helping to decipher the regulation rules of RNA.  

LAMAR was developed by Rnasys Lab and Bio-Med Big Data Center, Shanghai Institute of Nutrition and Health (SINH), Chinese Academy of Sciences (CAS).  

## Model weights

SpliceSitePred: Weight of fine-tuned LAMAR predict splice site of pre-mRNA  
UTR5TEPred: Weight of fine-tuned LAMAR predict translation efficiency of mRNA based on 5' UTR  
UTR3DegPred: Weight of fine-tuned LAMAR predict degradation rate of mRNA based on 3' UTR  
IRESPred: Weight of fine-tuned LAMAR predicting internal ribosome entry site (IRES)  

mammalian80D_2048len1mer1sw_80M: Pretrained weights of LAMAR-2k  
mammalian80D_4096len1mer1sw_80M: Pretrained weights of LAMAR-4k  

## Citation
https://www.biorxiv.org/content/10.1101/2024.10.12.617732v2

Github link: https://github.com/zhw-e8/LAMAR