transformers pytorch deberta-v2 text-classification medical en dataset:allenai/scifact autotrain_compatible endpoints_compatible region:us
---
datasets:
- allenai/scifact
language:
- en
metrics:
- accuracy
- f1
- precision
- recall
tags:
- medical
widget:
- text: X-linked genes, particularly those related to chromatin structure/remodeling,
    segregation, and ribosomal biogenesis and translational control, may also play
    key regulatory roles in breast carcinogenesis<SEP>While contribution of X chromosome
    in the susceptibility of prostate and ovarian cancer has been demonstrated, the
    role of X-linked genes in breast carcinogenesis is not clearly known. This study
    investigated and compared the X-linked gene expression profiles of MMTV-c-myc
    transgenic mammary tumor (MT) or MMTV-c-myc/MT-tgf-alpha double transgenic mouse
    mammary tumor (DT) to lactating mammary gland. cDNA microarray analysis using
    the Affymetrix system identified 1081 genes localized on the X chromosome with
    174 and 194 genes at +/-2-fold change levels in MT and DT samples, respectively.
    Differentially expressed X-linked genes were predominantly related to chromatin
    structure/remodeling (e.g., Hdac8, Suv39h1, RbAp46 and Adr1), segregation (e.g.,
    CENP-I and smc111) and, ribosomal biogenesis and translational control (e.g.,
    Dkc1, Rpl44, Rpl39, Eif2s3x, Gspt2 and Rsk4). Confirmation of microarray data
    by semi-quantitative and quantitative RT-PCR in selected X-linked genes also showed
    similar pattern. In addition, the expression pattern of two chromosomal regions,
    XE3 and XF5, suggests that XE3 may have escaped from inactivation and XF5 subjected
    to inactivation. In conclusion, our data suggest that X-linked genes may play
    the key regulatory roles in the maintenance of chromatin structure, accurate chromosomal
    segregation and translational control; hence deregulation of X-linked genes may
    promote mammary gland tumorigenesis by promoting genetic instability and cell
    proliferation. Increased understanding of the role of X-linked genes and genetic
    pathways will provide the strategies to develop the molecular therapeutics to
    treat and prevent reproductive related cancers.
---

# Textual Entailment for biomedical texts

## Model Description

This model is fine-tuned on SciFact dataset for textual antailment task in the domain of biomedicine.