In the Dictionary 'lumpy jaw' comes just before 'lunacy,' but in life there are no such clues. Suddenly, for no reason, you might start to dribble from the mouth, to howl peevishly at the moon. You might start quoting your mother, out loud and with conviction. You might lose your friends to the most uninspired of deaths. You might one day wake up and find yourself teaching at a community college; there will have been nothing to warn you. You might say things to your students like, There is only one valid theme in literature: Life will disappoint you.
Lorrie Moore, Anagrams
depression, disappointment, literature, lunacy, midlife-crisis